{"id":"https://openalex.org/W4319164454","doi":"https://doi.org/10.1093/bib/bbad033","title":"Bioinformatics toolbox for exploring target mutation-induced drug resistance","display_name":"Bioinformatics toolbox for exploring target mutation-induced drug resistance","publication_year":2023,"publication_date":"2023-02-04","ids":{"openalex":"https://openalex.org/W4319164454","doi":"https://doi.org/10.1093/bib/bbad033","pmid":"https://pubmed.ncbi.nlm.nih.gov/36738254"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbad033","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbad033","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062116671","display_name":"Yuanqin Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I178232147","display_name":"Guizhou University","ror":"https://ror.org/02wmsc916","country_code":"CN","type":"education","lineage":["https://openalex.org/I178232147"]},{"id":"https://openalex.org/I4210113472","display_name":"Shanghai Pesticide Research Institute","ror":"https://ror.org/024aa1608","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210113472"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan-Qin Huang","raw_affiliation_strings":["Guizhou University , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","National Key Laboratory of Green Pesticide , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guizhou University , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","institution_ids":["https://openalex.org/I178232147"]},{"raw_affiliation_string":"National Key Laboratory of Green Pesticide , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","institution_ids":["https://openalex.org/I4210113472"]},{"raw_affiliation_string":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P. R. China","institution_ids":["https://openalex.org/I178232147"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100614097","display_name":"Ping Sun","orcid":"https://orcid.org/0000-0003-4607-0592"},"institutions":[{"id":"https://openalex.org/I178232147","display_name":"Guizhou University","ror":"https://ror.org/02wmsc916","country_code":"CN","type":"education","lineage":["https://openalex.org/I178232147"]},{"id":"https://openalex.org/I4210113472","display_name":"Shanghai Pesticide Research Institute","ror":"https://ror.org/024aa1608","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210113472"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Sun","raw_affiliation_strings":["Guizhou University , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","National Key Laboratory of Green Pesticide , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guizhou University , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","institution_ids":["https://openalex.org/I178232147"]},{"raw_affiliation_string":"National Key Laboratory of Green Pesticide , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","institution_ids":["https://openalex.org/I4210113472"]},{"raw_affiliation_string":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P. R. China","institution_ids":["https://openalex.org/I178232147"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087644493","display_name":"Yi Chen","orcid":"https://orcid.org/0000-0003-3452-8412"},"institutions":[{"id":"https://openalex.org/I178232147","display_name":"Guizhou University","ror":"https://ror.org/02wmsc916","country_code":"CN","type":"education","lineage":["https://openalex.org/I178232147"]},{"id":"https://openalex.org/I4210113472","display_name":"Shanghai Pesticide Research Institute","ror":"https://ror.org/024aa1608","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210113472"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Chen","raw_affiliation_strings":["Guizhou University , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","National Key Laboratory of Green Pesticide , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guizhou University , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","institution_ids":["https://openalex.org/I178232147"]},{"raw_affiliation_string":"National Key Laboratory of Green Pesticide , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","institution_ids":["https://openalex.org/I4210113472"]},{"raw_affiliation_string":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P. R. China","institution_ids":["https://openalex.org/I178232147"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054987508","display_name":"Huanxiang Liu","orcid":"https://orcid.org/0000-0002-9284-3667"},"institutions":[{"id":"https://openalex.org/I49835588","display_name":"Macao Polytechnic University","ror":"https://ror.org/02sf5td35","country_code":"MO","type":"education","lineage":["https://openalex.org/I49835588"]}],"countries":["MO"],"is_corresponding":false,"raw_author_name":"Huan-Xiang Liu","raw_affiliation_strings":["Faculty of Applied Science, Macao Polytechnic University , Macao 999078, SAR , China"],"raw_orcid":"https://orcid.org/0000-0002-9284-3667","affiliations":[{"raw_affiliation_string":"Faculty of Applied Science, Macao Polytechnic University , Macao 999078, SAR , China","institution_ids":["https://openalex.org/I49835588"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068847247","display_name":"Ge\u2010Fei Hao","orcid":"https://orcid.org/0000-0003-4090-8411"},"institutions":[{"id":"https://openalex.org/I178232147","display_name":"Guizhou University","ror":"https://ror.org/02wmsc916","country_code":"CN","type":"education","lineage":["https://openalex.org/I178232147"]},{"id":"https://openalex.org/I4210113472","display_name":"Shanghai Pesticide Research Institute","ror":"https://ror.org/024aa1608","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210113472"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ge-Fei Hao","raw_affiliation_strings":["Guizhou University , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","National Key Laboratory of Green Pesticide , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guizhou University , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","institution_ids":["https://openalex.org/I178232147"]},{"raw_affiliation_string":"National Key Laboratory of Green Pesticide , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","institution_ids":["https://openalex.org/I4210113472"]},{"raw_affiliation_string":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P. R. China","institution_ids":["https://openalex.org/I178232147"]}]},{"author_position":"last","author":{"id":null,"display_name":"Bao-An Song","orcid":null},"institutions":[{"id":"https://openalex.org/I178232147","display_name":"Guizhou University","ror":"https://ror.org/02wmsc916","country_code":"CN","type":"education","lineage":["https://openalex.org/I178232147"]},{"id":"https://openalex.org/I4210113472","display_name":"Shanghai Pesticide Research Institute","ror":"https://ror.org/024aa1608","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210113472"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bao-An Song","raw_affiliation_strings":["Guizhou University , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","National Key Laboratory of Green Pesticide , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P. R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guizhou University , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","institution_ids":["https://openalex.org/I178232147"]},{"raw_affiliation_string":"National Key Laboratory of Green Pesticide , Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, , Guiyang 550025 , P. R. China","institution_ids":["https://openalex.org/I4210113472"]},{"raw_affiliation_string":"National Key Laboratory of Green Pesticide, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, P. R. China","institution_ids":["https://openalex.org/I178232147"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5068847247"],"corresponding_institution_ids":["https://openalex.org/I178232147","https://openalex.org/I4210113472"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":1.478,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.81498756,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":98},"biblio":{"volume":"24","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9799000024795532,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.9639999866485596,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/toolbox","display_name":"Toolbox","score":0.9098643064498901},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6215608716011047},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"Drug resistance","score":0.5429099202156067},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.48480120301246643},{"id":"https://openalex.org/keywords/resistance","display_name":"Resistance (ecology)","score":0.4824386537075043},{"id":"https://openalex.org/keywords/risk-analysis","display_name":"Risk analysis (engineering)","score":0.44556087255477905},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.44021451473236084},{"id":"https://openalex.org/keywords/drug-development","display_name":"Drug development","score":0.43114417791366577},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.4251408874988556},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.4244579076766968},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.37843018770217896},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.33722037076950073},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1861238181591034},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1834123134613037},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.12263938784599304},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.0940314531326294}],"concepts":[{"id":"https://openalex.org/C2777655017","wikidata":"https://www.wikidata.org/wiki/Q1501161","display_name":"Toolbox","level":2,"score":0.9098643064498901},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6215608716011047},{"id":"https://openalex.org/C114851261","wikidata":"https://www.wikidata.org/wiki/Q12147416","display_name":"Drug resistance","level":2,"score":0.5429099202156067},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.48480120301246643},{"id":"https://openalex.org/C57473165","wikidata":"https://www.wikidata.org/wiki/Q7315604","display_name":"Resistance (ecology)","level":2,"score":0.4824386537075043},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.44556087255477905},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.44021451473236084},{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.43114417791366577},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.4251408874988556},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4244579076766968},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.37843018770217896},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33722037076950073},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1861238181591034},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1834123134613037},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.12263938784599304},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0940314531326294},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D004351","descriptor_name":"Drug Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004351","descriptor_name":"Drug Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004351","descriptor_name":"Drug Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bib/bbad033","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbad033","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:36738254","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36738254","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.7799999713897705}],"awards":[{"id":"https://openalex.org/G2663285484","display_name":null,"funder_award_id":"32125033","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":125,"referenced_works":["https://openalex.org/W1549816642","https://openalex.org/W1965037740","https://openalex.org/W1982754849","https://openalex.org/W1987093848","https://openalex.org/W2020727616","https://openalex.org/W2027184506","https://openalex.org/W2042107321","https://openalex.org/W2050013640","https://openalex.org/W2064488723","https://openalex.org/W2070171305","https://openalex.org/W2076484532","https://openalex.org/W2090488060","https://openalex.org/W2094142315","https://openalex.org/W2099837668","https://openalex.org/W2101478678","https://openalex.org/W2103459989","https://openalex.org/W2121322641","https://openalex.org/W2125158282","https://openalex.org/W2125359610","https://openalex.org/W2129656399","https://openalex.org/W2131321938","https://openalex.org/W2131487381","https://openalex.org/W2153080167","https://openalex.org/W2154400082","https://openalex.org/W2155458048","https://openalex.org/W2158100429","https://openalex.org/W2169077388","https://openalex.org/W2194586233","https://openalex.org/W2236299009","https://openalex.org/W2272802268","https://openalex.org/W2291050268","https://openalex.org/W2300011769","https://openalex.org/W2305932671","https://openalex.org/W2335773464","https://openalex.org/W2419548415","https://openalex.org/W2428593791","https://openalex.org/W2460324897","https://openalex.org/W2475308546","https://openalex.org/W2528395340","https://openalex.org/W2544493586","https://openalex.org/W2553990959","https://openalex.org/W2557776122","https://openalex.org/W2558941103","https://openalex.org/W2573647331","https://openalex.org/W2594084827","https://openalex.org/W2606138983","https://openalex.org/W2615841538","https://openalex.org/W2722321450","https://openalex.org/W2735540821","https://openalex.org/W2739323458","https://openalex.org/W2790977261","https://openalex.org/W2792218462","https://openalex.org/W2792415891","https://openalex.org/W2792821195","https://openalex.org/W2793296617","https://openalex.org/W2795065364","https://openalex.org/W2798338906","https://openalex.org/W2801491392","https://openalex.org/W2803532708","https://openalex.org/W2804572516","https://openalex.org/W2889178232","https://openalex.org/W2897092933","https://openalex.org/W2898789672","https://openalex.org/W2913905751","https://openalex.org/W2914787675","https://openalex.org/W2919609620","https://openalex.org/W2920744809","https://openalex.org/W2920984376","https://openalex.org/W2921872415","https://openalex.org/W2937307539","https://openalex.org/W2941644628","https://openalex.org/W2943163666","https://openalex.org/W2943288764","https://openalex.org/W2945879841","https://openalex.org/W2947097964","https://openalex.org/W2951274106","https://openalex.org/W2952463453","https://openalex.org/W2954336754","https://openalex.org/W2967710850","https://openalex.org/W2982531601","https://openalex.org/W2983351185","https://openalex.org/W2983394854","https://openalex.org/W2986396864","https://openalex.org/W2988773550","https://openalex.org/W2999053232","https://openalex.org/W3004759689","https://openalex.org/W3007942792","https://openalex.org/W3022475467","https://openalex.org/W3028862763","https://openalex.org/W3031514813","https://openalex.org/W3033857285","https://openalex.org/W3042334871","https://openalex.org/W3046554421","https://openalex.org/W3093944744","https://openalex.org/W3096333766","https://openalex.org/W3097358871","https://openalex.org/W3108162704","https://openalex.org/W3109430993","https://openalex.org/W3112882148","https://openalex.org/W3117622225","https://openalex.org/W3133351047","https://openalex.org/W3165081806","https://openalex.org/W3165511231","https://openalex.org/W3170689505","https://openalex.org/W3183009512","https://openalex.org/W3189831819","https://openalex.org/W3196915693","https://openalex.org/W3199170050","https://openalex.org/W3199496883","https://openalex.org/W3206616748","https://openalex.org/W3210331473","https://openalex.org/W3213766511","https://openalex.org/W3213922610","https://openalex.org/W4210556001","https://openalex.org/W4210601364","https://openalex.org/W4236479494","https://openalex.org/W4297914773","https://openalex.org/W6647221310","https://openalex.org/W6679731850","https://openalex.org/W6686825414","https://openalex.org/W6751036913","https://openalex.org/W6760517126","https://openalex.org/W6769556952","https://openalex.org/W6799305659","https://openalex.org/W6803585655"],"related_works":["https://openalex.org/W4205140848","https://openalex.org/W2068663075","https://openalex.org/W2978678743","https://openalex.org/W2797837731","https://openalex.org/W4393677513","https://openalex.org/W4390832911","https://openalex.org/W829257147","https://openalex.org/W4385302116","https://openalex.org/W2127264463","https://openalex.org/W2764191054"],"abstract_inverted_index":{"Drug":[0],"resistance":[1,26,61,180],"is":[2],"increasingly":[3],"among":[4],"the":[5,37,127,147,162],"main":[6],"issues":[7],"affecting":[8],"human":[9],"health":[10],"and":[11,14,53,68,76,78,81,88,107,130,142,166,170],"threatening":[12],"agriculture":[13],"food":[15],"security.":[16],"In":[17],"particular,":[18],"developing":[19],"approaches":[20],"to":[21,46,176],"overcome":[22],"target":[23,101],"mutation-induced":[24,102],"drug":[25,51,60,103,179],"has":[27],"long":[28],"been":[29,44,85],"an":[30],"essential":[31],"part":[32],"of":[33,50,133],"biological":[34],"research.":[35],"During":[36],"past":[38],"decade,":[39],"many":[40],"bioinformatics":[41,97,165],"tools":[42,98,141],"have":[43,55,83],"developed":[45],"explore":[47],"this":[48,151],"type":[49],"resistance,":[52],"they":[54],"become":[56],"popular":[57],"for":[58,99,158,174],"elucidating":[59],"mechanisms":[62],"in":[63,161],"a":[64,155,171],"low":[65],"cost,":[66],"fast":[67],"effective":[69],"way.":[70],"However,":[71],"these":[72,109,134],"resources":[73,110],"are":[74],"scattered":[75],"underutilized,":[77],"their":[79,113],"strengths":[80],"limitations":[82,129],"not":[84],"systematically":[86,92],"analyzed":[87,106],"compared.":[89],"Here,":[90],"we":[91,124,137],"surveyed":[93],"59":[94],"freely":[95],"available":[96],"exploring":[100],"resistance.":[104],"We":[105],"summarized":[108],"based":[111],"on":[112],"functionality,":[114],"data":[115,117],"volume,":[116],"source,":[118],"operating":[119],"principle,":[120],"performance,":[121],"etc.":[122],"And":[123],"concisely":[125],"discussed":[126],"strengths,":[128],"application":[131],"examples":[132],"tools.":[135],"Specifically,":[136],"tested":[138],"some":[139,144],"predictive":[140],"offered":[143],"thoughts":[145],"from":[146],"clinician's":[148],"perspective.":[149],"Hopefully,":[150],"work":[152],"will":[153],"provide":[154],"useful":[156],"toolbox":[157],"researchers":[159],"working":[160],"biomedical,":[163],"pesticide,":[164],"pharmaceutical":[167],"engineering":[168],"fields,":[169],"good":[172],"platform":[173],"non-specialists":[175],"quickly":[177],"understand":[178],"prediction.":[181]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":5}],"updated_date":"2026-07-14T08:27:34.040176","created_date":"2025-10-10T00:00:00"}