{"id":"https://openalex.org/W4311860438","doi":"https://doi.org/10.1093/bib/bbac550","title":"dSCOPE: a software to detect sequences critical for liquid\u2013liquid phase separation","display_name":"dSCOPE: a software to detect sequences critical for liquid\u2013liquid phase separation","publication_year":2022,"publication_date":"2022-12-17","ids":{"openalex":"https://openalex.org/W4311860438","doi":"https://doi.org/10.1093/bib/bbac550","pmid":"https://pubmed.ncbi.nlm.nih.gov/36528388"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbac550","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbac550","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100692622","display_name":"Kai Yu","orcid":"https://orcid.org/0000-0003-3343-2902"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kai Yu","raw_affiliation_strings":["Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113426106","display_name":"Zekun Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zekun Liu","raw_affiliation_strings":["Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082089454","display_name":"Haoyang Cheng","orcid":"https://orcid.org/0000-0002-0756-6475"},"institutions":[{"id":"https://openalex.org/I889458895","display_name":"University of Hong Kong","ror":"https://ror.org/02zhqgq86","country_code":"HK","type":"education","lineage":["https://openalex.org/I889458895"]}],"countries":["HK"],"is_corresponding":false,"raw_author_name":"Haoyang Cheng","raw_affiliation_strings":["The University of Hong Kong Department of Computer Science, , Hong Kong 999077 , China"],"affiliations":[{"raw_affiliation_string":"The University of Hong Kong Department of Computer Science, , Hong Kong 999077 , China","institution_ids":["https://openalex.org/I889458895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100618287","display_name":"Shihua Li","orcid":"https://orcid.org/0000-0003-1775-6536"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shihua Li","raw_affiliation_strings":["Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100751896","display_name":"Qingfeng Zhang","orcid":"https://orcid.org/0000-0002-7004-9040"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingfeng Zhang","raw_affiliation_strings":["Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100409757","display_name":"Jia Liu","orcid":"https://orcid.org/0000-0003-2217-6982"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia Liu","raw_affiliation_strings":["Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050581018","display_name":"Huai\u2010Qiang Ju","orcid":"https://orcid.org/0000-0003-1713-5465"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huai-Qiang Ju","raw_affiliation_strings":["Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090129059","display_name":"Zhixiang Zuo","orcid":"https://orcid.org/0000-0002-2492-2689"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhixiang Zuo","raw_affiliation_strings":["Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055435419","display_name":"Qi Zhao","orcid":"https://orcid.org/0000-0002-8683-6145"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi Zhao","raw_affiliation_strings":["Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112226438","display_name":"Shiyang Kang","orcid":null},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shiyang Kang","raw_affiliation_strings":["Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027890976","display_name":"Zexian Liu","orcid":"https://orcid.org/0000-0001-9698-0610"},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ze-Xian Liu","raw_affiliation_strings":["Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China"],"affiliations":[{"raw_affiliation_string":"Sun Yat-sen University Cancer Center State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, , Guangzhou 510060 , China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5027890976","https://openalex.org/A5112226438"],"corresponding_institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":2.1662,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.88493532,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"24","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.982200026512146,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chromatography","display_name":"Chromatography","score":0.5662230253219604},{"id":"https://openalex.org/keywords/liquid-liquid","display_name":"Liquid liquid","score":0.5556089878082275},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.5454195737838745},{"id":"https://openalex.org/keywords/separation","display_name":"Separation (statistics)","score":0.5047811269760132},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.501239538192749},{"id":"https://openalex.org/keywords/liquid-phase","display_name":"Liquid phase","score":0.4981987476348877},{"id":"https://openalex.org/keywords/phase","display_name":"Phase (matter)","score":0.48370224237442017},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.3222699761390686},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.17792826890945435},{"id":"https://openalex.org/keywords/thermodynamics","display_name":"Thermodynamics","score":0.08089634776115417},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.05899035930633545},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.043608516454696655}],"concepts":[{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.5662230253219604},{"id":"https://openalex.org/C3017397382","wikidata":"https://www.wikidata.org/wiki/Q3242293","display_name":"Liquid liquid","level":2,"score":0.5556089878082275},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.5454195737838745},{"id":"https://openalex.org/C2776061190","wikidata":"https://www.wikidata.org/wiki/Q7451805","display_name":"Separation (statistics)","level":2,"score":0.5047811269760132},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.501239538192749},{"id":"https://openalex.org/C3020315061","wikidata":"https://www.wikidata.org/wiki/Q11435","display_name":"Liquid phase","level":2,"score":0.4981987476348877},{"id":"https://openalex.org/C44280652","wikidata":"https://www.wikidata.org/wiki/Q104837","display_name":"Phase (matter)","level":2,"score":0.48370224237442017},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3222699761390686},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.17792826890945435},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.08089634776115417},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.05899035930633545},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.043608516454696655},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bib/bbac550","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbac550","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:36528388","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36528388","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.7699999809265137,"display_name":"Life in Land","id":"https://metadata.un.org/sdg/15"}],"awards":[{"id":"https://openalex.org/G3183247085","display_name":null,"funder_award_id":"2021YFA1302100","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4207602180","display_name":null,"funder_award_id":"91953123","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5813784428","display_name":null,"funder_award_id":"2019TQ05Y351","funder_id":"https://openalex.org/F4320327806","funder_display_name":"Tip-top Scientific and Technical Innovative Youth Talents of Guangdong Special Support Program"},{"id":"https://openalex.org/G5877473216","display_name":null,"funder_award_id":"202206080011","funder_id":"https://openalex.org/F4320334898","funder_display_name":"Guangzhou Science and Technology Program key projects"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320327806","display_name":"Tip-top Scientific and Technical Innovative Youth Talents of Guangdong Special Support Program","ror":null},{"id":"https://openalex.org/F4320334898","display_name":"Guangzhou Science and Technology Program key projects","ror":"https://ror.org/00tjzgn92"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":76,"referenced_works":["https://openalex.org/W1952608303","https://openalex.org/W1972475361","https://openalex.org/W1975304761","https://openalex.org/W2027847170","https://openalex.org/W2035618305","https://openalex.org/W2047496561","https://openalex.org/W2049765837","https://openalex.org/W2053820259","https://openalex.org/W2076586303","https://openalex.org/W2081862209","https://openalex.org/W2102898524","https://openalex.org/W2105045982","https://openalex.org/W2107677817","https://openalex.org/W2111796925","https://openalex.org/W2115746733","https://openalex.org/W2133943800","https://openalex.org/W2139066576","https://openalex.org/W2139995722","https://openalex.org/W2140453812","https://openalex.org/W2143197682","https://openalex.org/W2153187042","https://openalex.org/W2155521690","https://openalex.org/W2156407548","https://openalex.org/W2157658519","https://openalex.org/W2162172965","https://openalex.org/W2163485494","https://openalex.org/W2168012258","https://openalex.org/W2223413920","https://openalex.org/W2268103735","https://openalex.org/W2404387744","https://openalex.org/W2517195794","https://openalex.org/W2590568317","https://openalex.org/W2694038906","https://openalex.org/W2722642526","https://openalex.org/W2743471889","https://openalex.org/W2765486298","https://openalex.org/W2767649956","https://openalex.org/W2784022040","https://openalex.org/W2788827529","https://openalex.org/W2792541660","https://openalex.org/W2794654572","https://openalex.org/W2798156059","https://openalex.org/W2810866092","https://openalex.org/W2883701024","https://openalex.org/W2887741043","https://openalex.org/W2889261354","https://openalex.org/W2898416998","https://openalex.org/W2900206619","https://openalex.org/W2901209536","https://openalex.org/W2913249938","https://openalex.org/W2914907359","https://openalex.org/W2917988060","https://openalex.org/W2943245415","https://openalex.org/W2945883683","https://openalex.org/W2949137513","https://openalex.org/W2949713051","https://openalex.org/W2950374603","https://openalex.org/W2954388258","https://openalex.org/W2955829592","https://openalex.org/W2958423850","https://openalex.org/W2971594646","https://openalex.org/W2973290848","https://openalex.org/W2977849281","https://openalex.org/W2980646921","https://openalex.org/W2989157079","https://openalex.org/W2991067665","https://openalex.org/W3003463974","https://openalex.org/W3136595937","https://openalex.org/W3136918052","https://openalex.org/W3156051371","https://openalex.org/W3166654832","https://openalex.org/W3191096373","https://openalex.org/W4281490610","https://openalex.org/W4281765256","https://openalex.org/W4292263320","https://openalex.org/W6799643758"],"related_works":["https://openalex.org/W2037754013","https://openalex.org/W2020371648","https://openalex.org/W4396829328","https://openalex.org/W2951203094","https://openalex.org/W1979676511","https://openalex.org/W1992508107","https://openalex.org/W2793485971","https://openalex.org/W1534710769","https://openalex.org/W2600010790","https://openalex.org/W2799927946"],"abstract_inverted_index":{"Membrane-based":[0],"cells":[1],"are":[2],"the":[3,22,41,57,77,82,138,151,168,181],"fundamental":[4],"structural":[5,104],"and":[6,31,105,147,150],"functional":[7],"units":[8],"of":[9,24,43,130],"organisms,":[10],"while":[11],"evidences":[12],"demonstrate":[13],"that":[14,60,90,137],"liquid-liquid":[15],"phase":[16,45],"separation":[17,46],"(LLPS)":[18],"is":[19],"associated":[20],"with":[21,175],"formation":[23],"membraneless":[25],"organelles,":[26],"such":[27],"as":[28],"P-bodies,":[29],"nucleoli":[30],"stress":[32],"granules.":[33],"Many":[34],"studies":[35,50],"have":[36],"been":[37],"undertaken":[38],"to":[39,55,75,114,123,183],"explore":[40],"functions":[42],"protein":[44,144,169],"(PS),":[47],"but":[48],"these":[49],"lacked":[51],"an":[52],"effective":[53],"tool":[54],"identify":[56],"sequence":[58,88,99,170],"segments":[59,89,171],"critical":[61,159,172],"for":[62,173],"LLPS.":[63],"In":[64],"this":[65],"study,":[66],"we":[67,84],"presented":[68],"a":[69],"novel":[70],"software":[71],"called":[72],"dSCOPE":[73,120,135,165],"(http://dscope.omicsbio.info)":[74],"predict":[76],"PS-driving":[78,140,156],"regions.":[79],"To":[80],"develop":[81],"predictor,":[83],"curated":[85],"experimentally":[86],"identified":[87],"can":[91],"drive":[92],"LLPS":[93],"from":[94],"published":[95],"literature.":[96],"Then":[97],"sliding":[98],"window":[100],"based":[101,133],"physiological,":[102],"biochemical,":[103],"coding":[106],"features":[107],"were":[108],"integrated":[109],"by":[110],"random":[111],"forest":[112],"algorithm":[113],"perform":[115],"prediction.":[116],"Through":[117],"rigorous":[118],"evaluation,":[119],"was":[121],"demonstrated":[122],"achieve":[124],"satisfactory":[125],"performance.":[126],"Furthermore,":[127],"large-scale":[128],"analysis":[129],"human":[131],"proteome":[132],"on":[134],"showed":[136],"predicted":[139,155,167],"regions":[141,157],"enriched":[142,158],"various":[143,176],"post-translational":[145],"modifications":[146],"cancer":[148],"mutations,":[149],"proteins":[152],"which":[153],"contain":[154],"cellular":[160],"signaling":[161],"pathways.":[162],"Taken":[163],"together,":[164],"precisely":[166],"LLPS,":[174],"helpful":[177],"information":[178],"visualized":[179],"in":[180],"webserver":[182],"facilitate":[184],"LLPS-related":[185],"research.":[186]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":7}],"updated_date":"2026-03-29T08:15:47.926485","created_date":"2025-10-10T00:00:00"}