{"id":"https://openalex.org/W4210882326","doi":"https://doi.org/10.1093/bib/bbac066","title":"Research progress of miRNA\u2013disease association prediction and comparison of related algorithms","display_name":"Research progress of miRNA\u2013disease association prediction and comparison of related algorithms","publication_year":2022,"publication_date":"2022-02-09","ids":{"openalex":"https://openalex.org/W4210882326","doi":"https://doi.org/10.1093/bib/bbac066","pmid":"https://pubmed.ncbi.nlm.nih.gov/35246678"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbac066","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbac066","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054977113","display_name":"Liang Yu","orcid":"https://orcid.org/0000-0002-8351-3332"},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Liang Yu","raw_affiliation_strings":["School of Computer Science and Technology, Xidian University, Xi\u2019an, China","School of Computer Science and Technology, Xidian University, Xi'an, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi\u2019an, China","institution_ids":["https://openalex.org/I149594827"]},{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi'an, China","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004130985","display_name":"Yujia Zheng","orcid":"https://orcid.org/0009-0003-5225-6366"},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yujia Zheng","raw_affiliation_strings":["School of Computer Science and Technology, Xidian University, Xi\u2019an, China","School of Computer Science and Technology, Xidian University, Xi'an, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi\u2019an, China","institution_ids":["https://openalex.org/I149594827"]},{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi'an, China","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034905535","display_name":"Bingyi Ju","orcid":null},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bingyi Ju","raw_affiliation_strings":["School of Computer Science and Technology, Xidian University, Xi\u2019an, China","School of Computer Science and Technology, Xidian University, Xi'an, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi\u2019an, China","institution_ids":["https://openalex.org/I149594827"]},{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi'an, China","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016729401","display_name":"Chunyan Ao","orcid":"https://orcid.org/0000-0002-3008-6357"},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunyan Ao","raw_affiliation_strings":["School of Computer Science and Technology, Xidian University, Xi\u2019an, China","School of Computer Science and Technology, Xidian University, Xi'an, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi\u2019an, China","institution_ids":["https://openalex.org/I149594827"]},{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi'an, China","institution_ids":["https://openalex.org/I149594827"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060109811","display_name":"Lin Gao","orcid":"https://orcid.org/0000-0001-6396-0787"},"institutions":[{"id":"https://openalex.org/I149594827","display_name":"Xidian University","ror":"https://ror.org/05s92vm98","country_code":"CN","type":"education","lineage":["https://openalex.org/I149594827"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lin Gao","raw_affiliation_strings":["School of Computer Science and Technology, Xidian University, Xi\u2019an, China","School of Computer Science and Technology, Xidian University, Xi'an, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi\u2019an, China","institution_ids":["https://openalex.org/I149594827"]},{"raw_affiliation_string":"School of Computer Science and Technology, Xidian University, Xi'an, China","institution_ids":["https://openalex.org/I149594827"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5054977113"],"corresponding_institution_ids":["https://openalex.org/I149594827"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":1.8991,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.8677161,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"23","issue":"3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6757301092147827},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.5459976196289062},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5278744101524353},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.4975138008594513},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.497285395860672},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.47563982009887695},{"id":"https://openalex.org/keywords/predictive-modelling","display_name":"Predictive modelling","score":0.4640912413597107},{"id":"https://openalex.org/keywords/association","display_name":"Association (psychology)","score":0.44114065170288086},{"id":"https://openalex.org/keywords/function","display_name":"Function (biology)","score":0.43894582986831665},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.39307737350463867},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.33892959356307983},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13506576418876648},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.11142736673355103}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6757301092147827},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.5459976196289062},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5278744101524353},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.4975138008594513},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.497285395860672},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.47563982009887695},{"id":"https://openalex.org/C45804977","wikidata":"https://www.wikidata.org/wiki/Q7239673","display_name":"Predictive modelling","level":2,"score":0.4640912413597107},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.44114065170288086},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.43894582986831665},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.39307737350463867},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.33892959356307983},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13506576418876648},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11142736673355103},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bib/bbac066","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbac066","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:35246678","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35246678","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1903355035","display_name":null,"funder_award_id":"61672406","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3591579384","display_name":null,"funder_award_id":"JB180307","funder_id":"https://openalex.org/F4320335787","funder_display_name":"Fundamental Research Funds for the Central Universities"},{"id":"https://openalex.org/G375568310","display_name":null,"funder_award_id":"62072353","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335787","display_name":"Fundamental Research Funds for the Central Universities","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W1436642346","https://openalex.org/W1594951361","https://openalex.org/W1763867024","https://openalex.org/W1967087625","https://openalex.org/W1987236914","https://openalex.org/W2004824191","https://openalex.org/W2014946489","https://openalex.org/W2022732522","https://openalex.org/W2027684023","https://openalex.org/W2048460015","https://openalex.org/W2053761479","https://openalex.org/W2060464767","https://openalex.org/W2077327925","https://openalex.org/W2100761975","https://openalex.org/W2106029302","https://openalex.org/W2125118217","https://openalex.org/W2128768066","https://openalex.org/W2130979840","https://openalex.org/W2132694427","https://openalex.org/W2141222510","https://openalex.org/W2145361279","https://openalex.org/W2146292498","https://openalex.org/W2152970345","https://openalex.org/W2158135353","https://openalex.org/W2257354231","https://openalex.org/W2258129851","https://openalex.org/W2410390867","https://openalex.org/W2416873003","https://openalex.org/W2511620854","https://openalex.org/W2537429907","https://openalex.org/W2601934706","https://openalex.org/W2607159126","https://openalex.org/W2609468276","https://openalex.org/W2735278091","https://openalex.org/W2750900465","https://openalex.org/W2752943586","https://openalex.org/W2765950793","https://openalex.org/W2766935102","https://openalex.org/W2767546566","https://openalex.org/W2771545712","https://openalex.org/W2780584018","https://openalex.org/W2781702232","https://openalex.org/W2795540478","https://openalex.org/W2799307902","https://openalex.org/W2805950880","https://openalex.org/W2809363952","https://openalex.org/W2890728516","https://openalex.org/W2895927009","https://openalex.org/W2896010121","https://openalex.org/W2896172590","https://openalex.org/W2898250372","https://openalex.org/W2902116368","https://openalex.org/W2903730942","https://openalex.org/W2904881507","https://openalex.org/W2913427136","https://openalex.org/W2915154887","https://openalex.org/W2915339508","https://openalex.org/W2923922207","https://openalex.org/W2926326388","https://openalex.org/W2926842391","https://openalex.org/W2927302367","https://openalex.org/W2942082579","https://openalex.org/W2942820662","https://openalex.org/W2967648188","https://openalex.org/W2969457906","https://openalex.org/W2972066899","https://openalex.org/W2976262099","https://openalex.org/W3048676704","https://openalex.org/W3099000562","https://openalex.org/W3215843819","https://openalex.org/W4246271082","https://openalex.org/W6638057232","https://openalex.org/W6749595737","https://openalex.org/W6758742563"],"related_works":["https://openalex.org/W2352440174","https://openalex.org/W4309440960","https://openalex.org/W2062168445","https://openalex.org/W2348940229","https://openalex.org/W2898732673","https://openalex.org/W2363046693","https://openalex.org/W2389491697","https://openalex.org/W4318612353","https://openalex.org/W4390939596","https://openalex.org/W4389829534"],"abstract_inverted_index":{"With":[0],"an":[1,17],"in-depth":[2],"understanding":[3],"of":[4,69,176],"noncoding":[5],"ribonucleic":[6],"acid":[7],"(RNA),":[8],"many":[9],"studies":[10],"have":[11,34],"shown":[12],"that":[13,129,173],"microRNA":[14],"(miRNA)":[15],"plays":[16],"important":[18],"role":[19],"in":[20,56,201],"human":[21],"diseases.":[22,44],"Because":[23],"traditional":[24],"biological":[25],"experiments":[26],"are":[27],"time-consuming":[28],"and":[29,43,59,81,88,100,110,136,181,193,195],"laborious,":[30],"new":[31],"calculation":[32,93],"methods":[33,131],"recently":[35],"been":[36],"developed":[37],"to":[38,65,114,179,197],"predict":[39],"associations":[40],"between":[41,191],"miRNA":[42,180,192],"In":[45,103],"this":[46,104],"review,":[47],"we":[48,74],"collected":[49],"various":[50,92],"miRNA-disease":[51,86,123],"association":[52],"prediction":[53,71,120,162],"models":[54,94],"proposed":[55],"recent":[57],"years":[58],"used":[60,79],"two":[61,106,169],"common":[62],"data":[63,83],"sets":[64],"evaluate":[66,116],"the":[67,70,77,91,130,137,160,167,174,189,202],"performance":[68],"models.":[72],"First,":[73],"systematically":[75,115],"summarized":[76],"commonly":[78],"databases":[80],"similarity":[82],"for":[84,98,122,187],"predicting":[85,188],"associations,":[87],"then":[89],"divided":[90],"into":[95],"four":[96],"categories":[97],"summary":[99,175],"detailed":[101],"introduction.":[102],"study,":[105],"independent":[107],"datasets":[108],"(D5430":[109],"D6088)":[111],"were":[112],"compiled":[113],"11":[117],"publicly":[118],"available":[119],"tools":[121,200],"associations.":[124],"The":[125,147],"experimental":[126],"results":[127],"indicate":[128],"based":[132,139,149],"on":[133,140,150],"information":[134],"dissemination":[135],"method":[138,148],"scoring":[141],"function":[142],"require":[143],"shorter":[144],"running":[145,157],"time.":[146],"matrix":[151],"transformation":[152],"often":[153],"requires":[154],"a":[155],"longer":[156],"time,":[158],"but":[159],"overall":[161],"result":[163],"is":[164],"better":[165],"than":[166],"previous":[168],"methods.":[170],"We":[171],"hope":[172],"work":[177],"related":[178],"disease":[182,194],"will":[183],"provide":[184],"comprehensive":[185],"knowledge":[186],"relationship":[190],"contribute":[196],"advanced":[198],"computation":[199],"future.":[203]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":2}],"updated_date":"2026-03-12T08:34:05.389933","created_date":"2025-10-10T00:00:00"}