{"id":"https://openalex.org/W4200424115","doi":"https://doi.org/10.1093/bib/bbab500","title":"Dual-Network Collaborative Matrix Factorization for predicting small molecule-miRNA associations","display_name":"Dual-Network Collaborative Matrix Factorization for predicting small molecule-miRNA associations","publication_year":2021,"publication_date":"2021-11-02","ids":{"openalex":"https://openalex.org/W4200424115","doi":"https://doi.org/10.1093/bib/bbab500","pmid":"https://pubmed.ncbi.nlm.nih.gov/34864865"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbab500","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbab500","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100648787","display_name":"Shuhao Wang","orcid":"https://orcid.org/0000-0002-5467-3548"},"institutions":[{"id":"https://openalex.org/I25757504","display_name":"China University of Mining and Technology","ror":"https://ror.org/01xt2dr21","country_code":"CN","type":"education","lineage":["https://openalex.org/I25757504"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shu-Hao Wang","raw_affiliation_strings":["Artificial Intelligence Research Institute, China University of Mining and Technology, Xuzhou, 221116, China","School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, 221116, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Artificial Intelligence Research Institute, China University of Mining and Technology, Xuzhou, 221116, China","institution_ids":["https://openalex.org/I25757504"]},{"raw_affiliation_string":"School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, 221116, China","institution_ids":["https://openalex.org/I25757504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027613930","display_name":"Chun-Chun Wang","orcid":"https://orcid.org/0000-0002-6795-4007"},"institutions":[{"id":"https://openalex.org/I25757504","display_name":"China University of Mining and Technology","ror":"https://ror.org/01xt2dr21","country_code":"CN","type":"education","lineage":["https://openalex.org/I25757504"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chun-Chun Wang","raw_affiliation_strings":["Artificial Intelligence Research Institute, China University of Mining and Technology, Xuzhou, 221116, China","School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, 221116, China"],"raw_orcid":"https://orcid.org/0000-0002-6795-4007","affiliations":[{"raw_affiliation_string":"Artificial Intelligence Research Institute, China University of Mining and Technology, Xuzhou, 221116, China","institution_ids":["https://openalex.org/I25757504"]},{"raw_affiliation_string":"School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, 221116, China","institution_ids":["https://openalex.org/I25757504"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100744865","display_name":"Huang Li","orcid":"https://orcid.org/0000-0003-4669-3466"},"institutions":[{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Li Huang","raw_affiliation_strings":["Academy of Arts and Design, Tsinghua University, Beijing, 10084, China","The Future Laboratory, Tsinghua University, Beijing, 10084, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Academy of Arts and Design, Tsinghua University, Beijing, 10084, China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"The Future Laboratory, Tsinghua University, Beijing, 10084, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109952481","display_name":"Lianying Miao","orcid":null},"institutions":[{"id":"https://openalex.org/I25757504","display_name":"China University of Mining and Technology","ror":"https://ror.org/01xt2dr21","country_code":"CN","type":"education","lineage":["https://openalex.org/I25757504"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lian-Ying Miao","raw_affiliation_strings":["School of Mathematics, China University of Mining and Technology, Xuzhou, 221116, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Mathematics, China University of Mining and Technology, Xuzhou, 221116, China","institution_ids":["https://openalex.org/I25757504"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036210249","display_name":"Xing Chen","orcid":"https://orcid.org/0000-0001-9028-5342"},"institutions":[{"id":"https://openalex.org/I25757504","display_name":"China University of Mining and Technology","ror":"https://ror.org/01xt2dr21","country_code":"CN","type":"education","lineage":["https://openalex.org/I25757504"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xing Chen","raw_affiliation_strings":["Artificial Intelligence Research Institute, China University of Mining and Technology, Xuzhou, 221116, China","School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, 221116, China"],"raw_orcid":"https://orcid.org/0000-0001-9028-5342","affiliations":[{"raw_affiliation_string":"Artificial Intelligence Research Institute, China University of Mining and Technology, Xuzhou, 221116, China","institution_ids":["https://openalex.org/I25757504"]},{"raw_affiliation_string":"School of Information and Control Engineering, China University of Mining and Technology, Xuzhou, 221116, China","institution_ids":["https://openalex.org/I25757504"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5036210249"],"corresponding_institution_ids":["https://openalex.org/I25757504"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":2.3874,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.90169532,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"23","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11765","display_name":"Circular RNAs in diseases","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/matrix-decomposition","display_name":"Matrix decomposition","score":0.5669583678245544},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.5555324554443359},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5495058298110962},{"id":"https://openalex.org/keywords/dual","display_name":"Dual (grammatical number)","score":0.5346402525901794},{"id":"https://openalex.org/keywords/cross-validation","display_name":"Cross-validation","score":0.5149641633033752},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.49408987164497375},{"id":"https://openalex.org/keywords/matrix","display_name":"Matrix (chemical analysis)","score":0.49055999517440796},{"id":"https://openalex.org/keywords/non-negative-matrix-factorization","display_name":"Non-negative matrix factorization","score":0.46065422892570496},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4574820399284363},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4158284366130829},{"id":"https://openalex.org/keywords/association","display_name":"Association (psychology)","score":0.41494956612586975},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.39230841398239136},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.3499454855918884}],"concepts":[{"id":"https://openalex.org/C42355184","wikidata":"https://www.wikidata.org/wiki/Q1361088","display_name":"Matrix decomposition","level":3,"score":0.5669583678245544},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.5555324554443359},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5495058298110962},{"id":"https://openalex.org/C2780980858","wikidata":"https://www.wikidata.org/wiki/Q110022","display_name":"Dual (grammatical number)","level":2,"score":0.5346402525901794},{"id":"https://openalex.org/C27181475","wikidata":"https://www.wikidata.org/wiki/Q541014","display_name":"Cross-validation","level":2,"score":0.5149641633033752},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.49408987164497375},{"id":"https://openalex.org/C106487976","wikidata":"https://www.wikidata.org/wiki/Q685816","display_name":"Matrix (chemical analysis)","level":2,"score":0.49055999517440796},{"id":"https://openalex.org/C152671427","wikidata":"https://www.wikidata.org/wiki/Q10843505","display_name":"Non-negative matrix factorization","level":4,"score":0.46065422892570496},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4574820399284363},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4158284366130829},{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.41494956612586975},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.39230841398239136},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.3499454855918884},{"id":"https://openalex.org/C158693339","wikidata":"https://www.wikidata.org/wiki/Q190524","display_name":"Eigenvalues and eigenvectors","level":2,"score":0.0},{"id":"https://openalex.org/C124952713","wikidata":"https://www.wikidata.org/wiki/Q8242","display_name":"Literature","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020022","descriptor_name":"Genetic Predisposition to Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bib/bbab500","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbab500","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:34864865","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34864865","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Partnerships for the goals","score":0.4399999976158142,"id":"https://metadata.un.org/sdg/17"}],"awards":[{"id":"https://openalex.org/G3220252743","display_name":"\u57fa\u4e8e\u56fe\u4e0e\u7ec4\u5408\u4f18\u5316\u7684\u751f\u7269\u6570\u636e\u548c\u7f51\u7edc\u6570\u636e\u6316\u6398\u7b97\u6cd5\u7814\u7a76","funder_award_id":"11931008","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G579333840","display_name":"\u57fa\u4e8e\u591a\u6e90\u6570\u636e\u878d\u5408\u7684\u836f\u7269\u54cd\u5e94\u548c\u836f\u7269\u76f8\u5173\u975e\u7f16\u7801RNA\u9776\u70b9\u9884\u6d4b\u7814\u7a76","funder_award_id":"61972399","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":70,"referenced_works":["https://openalex.org/W144423133","https://openalex.org/W1889514258","https://openalex.org/W1975441976","https://openalex.org/W1979537657","https://openalex.org/W1986903527","https://openalex.org/W1989454102","https://openalex.org/W1989872688","https://openalex.org/W1994415948","https://openalex.org/W2008926604","https://openalex.org/W2014946489","https://openalex.org/W2015858554","https://openalex.org/W2023316880","https://openalex.org/W2027744584","https://openalex.org/W2040960125","https://openalex.org/W2047146433","https://openalex.org/W2047967134","https://openalex.org/W2053861881","https://openalex.org/W2062290101","https://openalex.org/W2070777085","https://openalex.org/W2087438476","https://openalex.org/W2087975583","https://openalex.org/W2090863707","https://openalex.org/W2097226863","https://openalex.org/W2106210472","https://openalex.org/W2107101690","https://openalex.org/W2109115947","https://openalex.org/W2113072832","https://openalex.org/W2117391818","https://openalex.org/W2120653843","https://openalex.org/W2123602182","https://openalex.org/W2127553917","https://openalex.org/W2128768066","https://openalex.org/W2130979840","https://openalex.org/W2135007932","https://openalex.org/W2137052779","https://openalex.org/W2138664009","https://openalex.org/W2142572836","https://openalex.org/W2153210075","https://openalex.org/W2154654747","https://openalex.org/W2160467221","https://openalex.org/W2162674813","https://openalex.org/W2163169932","https://openalex.org/W2167398093","https://openalex.org/W2171296186","https://openalex.org/W2203231406","https://openalex.org/W2259538443","https://openalex.org/W2343107734","https://openalex.org/W2364692879","https://openalex.org/W2395168605","https://openalex.org/W2443187137","https://openalex.org/W2502698579","https://openalex.org/W2591668896","https://openalex.org/W2606619264","https://openalex.org/W2736520162","https://openalex.org/W2750900465","https://openalex.org/W2759279048","https://openalex.org/W2765950793","https://openalex.org/W2773303607","https://openalex.org/W2809893308","https://openalex.org/W2884985642","https://openalex.org/W2896829849","https://openalex.org/W2896907688","https://openalex.org/W2912204568","https://openalex.org/W2945357511","https://openalex.org/W2946952196","https://openalex.org/W3138771162","https://openalex.org/W4238185726","https://openalex.org/W6753198614","https://openalex.org/W6755952022","https://openalex.org/W6792221166"],"related_works":["https://openalex.org/W2127243424","https://openalex.org/W4390394189","https://openalex.org/W2037504162","https://openalex.org/W2539013788","https://openalex.org/W2792706544","https://openalex.org/W1568451138","https://openalex.org/W2156699640","https://openalex.org/W2045265907","https://openalex.org/W2972997031","https://openalex.org/W34555840"],"abstract_inverted_index":{"MicroRNAs":[0],"(miRNAs)":[1],"play":[2],"crucial":[3],"roles":[4],"in":[5,207],"multiple":[6],"biological":[7,24],"processes":[8],"and":[9,12,33,98,140,172,200,219],"human":[10],"diseases":[11],"can":[13,132,146],"be":[14],"considered":[15],"as":[16],"therapeutic":[17],"targets":[18],"of":[19,96,115,122,129,137,143,158,193,227],"small":[20],"molecules":[21],"(SMs).":[22],"Because":[23],"experiments":[25],"used":[26],"to":[27,38,43,77,88,243],"verify":[28],"SM-miRNA":[29,46,64,79,104,246],"associations":[30,229],"are":[31],"time-consuming":[32],"expensive,":[34],"it":[35],"is":[36,239],"urgent":[37],"propose":[39],"new":[40,45],"computational":[41],"models":[42],"predict":[44,244],"associations.":[47,65,247],"Here,":[48],"we":[49,67,83,160],"proposed":[50],"a":[51],"novel":[52],"method":[53,76,124,131],"called":[54],"Dual-network":[55],"Collaborative":[56],"Matrix":[57],"Factorization":[58],"(DCMF)":[59],"for":[60],"predicting":[61],"the":[62,69,102,112,127,134,141,156],"potential":[63,245],"Firstly,":[66],"utilized":[68],"Weighted":[70],"K":[71],"Nearest":[72],"Known":[73],"Neighbors":[74],"(WKNKN)":[75],"preprocess":[78,133],"association":[80,105,138],"matrix.":[81],"Then,":[82],"constructed":[84],"matrix":[85,107,139],"factorization":[86],"model":[87],"obtain":[89],"two":[90,116,169,173],"feature":[91,117],"matrices":[92],"containing":[93],"latent":[94],"features":[95],"SM":[97],"miRNA,":[99],"respectively.":[100,222],"Finally,":[101,177],"predicted":[103,228],"score":[106],"was":[108],"obtained":[109],"by":[110,233],"calculating":[111],"inner":[113],"product":[114],"matrices.":[118],"The":[119],"main":[120],"innovations":[121],"this":[123],"were":[125],"that":[126],"use":[128],"WKNKN":[130],"missing":[135],"values":[136],"introduction":[142],"dual":[144],"network":[145],"integrate":[147],"more":[148],"diverse":[149],"similarity":[150],"information":[151],"into":[152],"DCMF.":[153],"For":[154,223],"evaluating":[155],"validity":[157],"DCMF,":[159],"implemented":[161],"four":[162],"different":[163,174],"cross":[164],"validations":[165],"(CVs)":[166],"based":[167,178],"on":[168,179],"distinct":[170],"datasets":[171],"case":[175,224],"studies.":[176],"dataset":[180],"1":[181],"(dataset":[182],"2),":[183],"DCMF":[184,238],"achieved":[185],"Area":[186],"Under":[187],"receiver":[188],"operating":[189],"characteristic":[190],"Curves":[191],"(AUC)":[192],"0.9868":[194],"(0.8770),":[195],"0.9833":[196],"(0.8836),":[197],"0.8377":[198],"(0.7591)":[199],"0.9836":[201],"\u00b1":[202,205],"0.0030":[203],"(0.8632":[204],"0.0042)":[206],"global":[208],"Leave-One-Out":[209],"Cross":[210],"Validation":[211],"(LOOCV),":[212],"miRNA-fixed":[213],"local":[214,217],"LOOCV,":[215],"SM-fixed":[216],"LOOCV":[218],"5-fold":[220],"CV,":[221],"studies,":[225],"plenty":[226],"have":[230],"been":[231],"confirmed":[232],"published":[234],"experimental":[235],"literature.":[236],"Therefore,":[237],"an":[240],"effective":[241],"tool":[242]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":6}],"updated_date":"2026-06-18T10:00:31.954636","created_date":"2025-10-10T00:00:00"}