{"id":"https://openalex.org/W3193314306","doi":"https://doi.org/10.1093/bib/bbab320","title":"Application of artificial intelligence and machine learning for COVID-19 drug discovery and vaccine design","display_name":"Application of artificial intelligence and machine learning for COVID-19 drug discovery and vaccine design","publication_year":2021,"publication_date":"2021-07-24","ids":{"openalex":"https://openalex.org/W3193314306","doi":"https://doi.org/10.1093/bib/bbab320","mag":"3193314306","pmid":"https://pubmed.ncbi.nlm.nih.gov/34410360"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbab320","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbab320","pdf_url":"https://academic.oup.com/bib/article-pdf/22/6/bbab320/41090150/bbab320.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://academic.oup.com/bib/article-pdf/22/6/bbab320/41090150/bbab320.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025728076","display_name":"Hao Lv","orcid":"https://orcid.org/0000-0002-7580-0155"},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Lv","raw_affiliation_strings":["Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018223305","display_name":"Lei Shi","orcid":"https://orcid.org/0000-0001-5709-6515"},"institutions":[{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Shi","raw_affiliation_strings":["Department of Spine Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200433, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Spine Surgery, Changzheng Hospital, Naval Medical University, Shanghai 200433, China","institution_ids":["https://openalex.org/I4210099558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069367626","display_name":"Joshua William Berkenpas","orcid":null},"institutions":[{"id":"https://openalex.org/I60065076","display_name":"Pacific Lutheran University","ror":"https://ror.org/01vh5nd96","country_code":"US","type":"education","lineage":["https://openalex.org/I60065076"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua William Berkenpas","raw_affiliation_strings":["Department of Computer Science, Pacific Lutheran University, Tacoma 98447, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Pacific Lutheran University, Tacoma 98447, USA","institution_ids":["https://openalex.org/I60065076"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050257316","display_name":"Fanny Dao","orcid":"https://orcid.org/0000-0001-5285-6044"},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fu-Ying Dao","raw_affiliation_strings":["Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026505260","display_name":"Hasan Zulfiqar","orcid":"https://orcid.org/0000-0002-8526-371X"},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hasan Zulfiqar","raw_affiliation_strings":["Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062628676","display_name":"Hui Ding","orcid":"https://orcid.org/0000-0002-9607-9571"},"institutions":[{"id":"https://openalex.org/I150229711","display_name":"University of Electronic Science and Technology of China","ror":"https://ror.org/04qr3zq92","country_code":"CN","type":"education","lineage":["https://openalex.org/I150229711"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Ding","raw_affiliation_strings":["Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu 610054, China","institution_ids":["https://openalex.org/I150229711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100354636","display_name":"Yang Zhang","orcid":"https://orcid.org/0000-0002-1317-120X"},"institutions":[{"id":"https://openalex.org/I53411278","display_name":"Chengdu University of Traditional Chinese Medicine","ror":"https://ror.org/00pcrz470","country_code":"CN","type":"education","lineage":["https://openalex.org/I53411278"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yang Zhang","raw_affiliation_strings":["Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China","institution_ids":["https://openalex.org/I53411278"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100662124","display_name":"Liming Yang","orcid":"https://orcid.org/0000-0002-0390-8845"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Liming Yang","raw_affiliation_strings":["Department of Pathophysiology, Harbin Medical University-Daqing, Daqing, 163319, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathophysiology, Harbin Medical University-Daqing, Daqing, 163319, China","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085487073","display_name":"Renzhi Cao","orcid":"https://orcid.org/0000-0002-8345-343X"},"institutions":[{"id":"https://openalex.org/I60065076","display_name":"Pacific Lutheran University","ror":"https://ror.org/01vh5nd96","country_code":"US","type":"education","lineage":["https://openalex.org/I60065076"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Renzhi Cao","raw_affiliation_strings":["Department of Computer Science, Pacific Lutheran University, Tacoma 98447, USA"],"raw_orcid":"https://orcid.org/0000-0002-8345-343X","affiliations":[{"raw_affiliation_string":"Department of Computer Science, Pacific Lutheran University, Tacoma 98447, USA","institution_ids":["https://openalex.org/I60065076"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5085487073","https://openalex.org/A5100354636","https://openalex.org/A5100662124"],"corresponding_institution_ids":["https://openalex.org/I156144747","https://openalex.org/I53411278","https://openalex.org/I60065076"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":5.2828,"has_fulltext":true,"cited_by_count":105,"citation_normalized_percentile":{"value":0.96621597,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"22","issue":"6","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9933000206947327,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coronavirus-disease-2019","display_name":"Coronavirus disease 2019 (COVID-19)","score":0.874893307685852},{"id":"https://openalex.org/keywords/pandemic","display_name":"Pandemic","score":0.8180749416351318},{"id":"https://openalex.org/keywords/severe-acute-respiratory-syndrome-coronavirus-2","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","score":0.7112679481506348},{"id":"https://openalex.org/keywords/2019-20-coronavirus-outbreak","display_name":"2019-20 coronavirus outbreak","score":0.6727880835533142},{"id":"https://openalex.org/keywords/coronavirus","display_name":"Coronavirus","score":0.591960072517395},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.5791205763816833},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5032066702842712},{"id":"https://openalex.org/keywords/outbreak","display_name":"Outbreak","score":0.48088768124580383},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.46961408853530884},{"id":"https://openalex.org/keywords/virology","display_name":"Virology","score":0.4209687113761902},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.369340181350708},{"id":"https://openalex.org/keywords/intensive-care-medicine","display_name":"Intensive care medicine","score":0.3425687551498413},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.28150343894958496},{"id":"https://openalex.org/keywords/infectious-disease","display_name":"Infectious disease (medical specialty)","score":0.2786555290222168},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.1620287001132965},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1480167806148529}],"concepts":[{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.874893307685852},{"id":"https://openalex.org/C89623803","wikidata":"https://www.wikidata.org/wiki/Q12184","display_name":"Pandemic","level":5,"score":0.8180749416351318},{"id":"https://openalex.org/C3007834351","wikidata":"https://www.wikidata.org/wiki/Q82069695","display_name":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)","level":5,"score":0.7112679481506348},{"id":"https://openalex.org/C3006700255","wikidata":"https://www.wikidata.org/wiki/Q81068910","display_name":"2019-20 coronavirus outbreak","level":3,"score":0.6727880835533142},{"id":"https://openalex.org/C2777648638","wikidata":"https://www.wikidata.org/wiki/Q57751738","display_name":"Coronavirus","level":5,"score":0.591960072517395},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.5791205763816833},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5032066702842712},{"id":"https://openalex.org/C116675565","wikidata":"https://www.wikidata.org/wiki/Q3241045","display_name":"Outbreak","level":2,"score":0.48088768124580383},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.46961408853530884},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.4209687113761902},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.369340181350708},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3425687551498413},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.28150343894958496},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.2786555290222168},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.1620287001132965},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1480167806148529},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000086663","descriptor_name":"COVID-19 Vaccines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086663","descriptor_name":"COVID-19 Vaccines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086663","descriptor_name":"COVID-19 Vaccines","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000086663","descriptor_name":"COVID-19 Vaccines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000086663","descriptor_name":"COVID-19 Vaccines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000086663","descriptor_name":"COVID-19 Vaccines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000093485","descriptor_name":"COVID-19 Drug Treatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000093485","descriptor_name":"COVID-19 Drug Treatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000093485","descriptor_name":"COVID-19 Drug Treatment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001185","descriptor_name":"Artificial Intelligence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D058873","descriptor_name":"Pandemics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058873","descriptor_name":"Pandemics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058873","descriptor_name":"Pandemics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1093/bib/bbab320","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbab320","pdf_url":"https://academic.oup.com/bib/article-pdf/22/6/bbab320/41090150/bbab320.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:34410360","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34410360","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8511807","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8511807","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/bib/bbab320","is_oa":true,"landing_page_url":"https://doi.org/10.1093/bib/bbab320","pdf_url":"https://academic.oup.com/bib/article-pdf/22/6/bbab320/41090150/bbab320.pdf","source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8600000143051147}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3193314306.pdf","grobid_xml":"https://content.openalex.org/works/W3193314306.grobid-xml"},"referenced_works_count":83,"referenced_works":["https://openalex.org/W1991244466","https://openalex.org/W2735922348","https://openalex.org/W2806146459","https://openalex.org/W2813360597","https://openalex.org/W2903899730","https://openalex.org/W2913961829","https://openalex.org/W2914971047","https://openalex.org/W2917923243","https://openalex.org/W2945027804","https://openalex.org/W2946099214","https://openalex.org/W2955298953","https://openalex.org/W2963018604","https://openalex.org/W2980754856","https://openalex.org/W2989670486","https://openalex.org/W2997008807","https://openalex.org/W2999580270","https://openalex.org/W3000834295","https://openalex.org/W3004874934","https://openalex.org/W3005045669","https://openalex.org/W3005560263","https://openalex.org/W3006541846","https://openalex.org/W3008785685","https://openalex.org/W3009548091","https://openalex.org/W3009609618","https://openalex.org/W3009970748","https://openalex.org/W3012994592","https://openalex.org/W3015059505","https://openalex.org/W3017271475","https://openalex.org/W3022285953","https://openalex.org/W3023906977","https://openalex.org/W3032843171","https://openalex.org/W3032892710","https://openalex.org/W3040508291","https://openalex.org/W3040868792","https://openalex.org/W3041467169","https://openalex.org/W3043611443","https://openalex.org/W3047350847","https://openalex.org/W3048531412","https://openalex.org/W3048600721","https://openalex.org/W3080576869","https://openalex.org/W3088524524","https://openalex.org/W3089346069","https://openalex.org/W3090171308","https://openalex.org/W3090236114","https://openalex.org/W3090504776","https://openalex.org/W3098521774","https://openalex.org/W3101796750","https://openalex.org/W3103820312","https://openalex.org/W3105440156","https://openalex.org/W3107281945","https://openalex.org/W3111643303","https://openalex.org/W3114967583","https://openalex.org/W3115254893","https://openalex.org/W3119705197","https://openalex.org/W3120003509","https://openalex.org/W3127277789","https://openalex.org/W3127588251","https://openalex.org/W3127707417","https://openalex.org/W3128378288","https://openalex.org/W3128822439","https://openalex.org/W3128961456","https://openalex.org/W3131121088","https://openalex.org/W3132273599","https://openalex.org/W3135521497","https://openalex.org/W3158868742","https://openalex.org/W3159193120","https://openalex.org/W3159592735","https://openalex.org/W3160549636","https://openalex.org/W3160988990","https://openalex.org/W3164716914","https://openalex.org/W3167419454","https://openalex.org/W3177553934","https://openalex.org/W4281570112","https://openalex.org/W4322577643","https://openalex.org/W4384007969","https://openalex.org/W6759104856","https://openalex.org/W6774211881","https://openalex.org/W6774259129","https://openalex.org/W6774652378","https://openalex.org/W6775330246","https://openalex.org/W6776733866","https://openalex.org/W6795904548","https://openalex.org/W6850298084"],"related_works":["https://openalex.org/W4200329650","https://openalex.org/W3127156785","https://openalex.org/W3009669391","https://openalex.org/W4206669628","https://openalex.org/W3113664224","https://openalex.org/W4205317059","https://openalex.org/W3005417802","https://openalex.org/W3084498529","https://openalex.org/W3022409537","https://openalex.org/W4226296940"],"abstract_inverted_index":{"The":[0],"global":[1],"pandemic":[2],"of":[3,22,31,61,78],"coronavirus":[4,14],"disease":[5],"2019":[6],"(COVID-19),":[7],"caused":[8],"by":[9,65],"severe":[10],"acute":[11],"respiratory":[12],"syndrome":[13],"2,":[15],"has":[16],"led":[17],"to":[18,104],"a":[19],"dramatic":[20],"loss":[21],"human":[23],"life":[24],"worldwide.":[25],"Despite":[26],"many":[27],"efforts,":[28],"the":[29,57,76,87,95,107,121,130],"development":[30],"effective":[32],"drugs":[33],"and":[34,47,59,80,97,124,127],"vaccines":[35],"for":[36,82],"this":[37,68,113],"novel":[38],"virus":[39],"will":[40],"take":[41],"considerable":[42],"time.":[43],"Artificial":[44],"intelligence":[45],"(AI)":[46],"machine":[48],"learning":[49],"(ML)":[50],"offer":[51],"promising":[52],"solutions":[53,103],"that":[54,112],"could":[55],"accelerate":[56],"discovery":[58],"optimization":[60],"new":[62,118],"antivirals.":[63],"Motivated":[64],"this,":[66],"in":[67],"paper,":[69],"we":[70,92],"present":[71],"an":[72],"extensive":[73],"survey":[74],"on":[75,86],"application":[77],"AI":[79,123],"ML":[81,125],"combating":[83],"COVID-19":[84,108,131],"based":[85],"rapidly":[88],"emerging":[89],"literature.":[90],"Particularly,":[91],"point":[93],"out":[94],"challenges":[96],"future":[98],"directions":[99],"associated":[100],"with":[101,117],"state-of-the-art":[102],"effectively":[105],"control":[106],"pandemic.":[109],"We":[110],"hope":[111],"review":[114],"provides":[115],"researchers":[116],"insights":[119],"into":[120],"ways":[122],"fight":[126],"have":[128],"fought":[129],"outbreak.":[132]},"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":28},{"year":2023,"cited_by_count":24},{"year":2022,"cited_by_count":29},{"year":2021,"cited_by_count":1}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}