{"id":"https://openalex.org/W3110828293","doi":"https://doi.org/10.1093/bib/bbaa312","title":"Large-scale comparative review and assessment of computational methods for anti-cancer peptide identification","display_name":"Large-scale comparative review and assessment of computational methods for anti-cancer peptide identification","publication_year":2020,"publication_date":"2020-10-19","ids":{"openalex":"https://openalex.org/W3110828293","doi":"https://doi.org/10.1093/bib/bbaa312","mag":"3110828293","pmid":"https://pubmed.ncbi.nlm.nih.gov/33316035"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbaa312","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbaa312","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8294543","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088119866","display_name":"Xiao Liang","orcid":"https://orcid.org/0000-0003-1967-362X"},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiao Liang","raw_affiliation_strings":["College of Information Engineering, Northwest A&F University, Yangling, 712100, China","Shaanxi Key Laboratory of Agricultural Information Perception and Intelligent Service, Yangling, Shaanxi 712100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Information Engineering, Northwest A&F University, Yangling, 712100, China","institution_ids":["https://openalex.org/I89652312"]},{"raw_affiliation_string":"Shaanxi Key Laboratory of Agricultural Information Perception and Intelligent Service, Yangling, Shaanxi 712100, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063409460","display_name":"Fuyi Li","orcid":"https://orcid.org/0000-0001-5216-3213"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]},{"id":"https://openalex.org/I4210105123","display_name":"Peter Doherty Institute","ror":"https://ror.org/016899r71","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1320473756","https://openalex.org/I165779595","https://openalex.org/I4210105123","https://openalex.org/I4210158168"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Fuyi Li","raw_affiliation_strings":["Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia","Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC 3800, Australia","Monash Centre for Data Science, Monash University, Melbourne, VIC 3800, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia","institution_ids":["https://openalex.org/I4210105123","https://openalex.org/I165779595"]},{"raw_affiliation_string":"Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC 3800, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Monash Centre for Data Science, Monash University, Melbourne, VIC 3800, Australia","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101556251","display_name":"Jin-Xiang Chen","orcid":"https://orcid.org/0000-0002-3963-0718"},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinxiang Chen","raw_affiliation_strings":["College of Information Engineering, Northwest A&F University, Yangling, 712100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Information Engineering, Northwest A&F University, Yangling, 712100, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100757066","display_name":"Jun\u2010Long Li","orcid":"https://orcid.org/0000-0002-4700-0142"},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junlong Li","raw_affiliation_strings":["College of Information Engineering, Northwest A&F University, Yangling, 712100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Information Engineering, Northwest A&F University, Yangling, 712100, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036176693","display_name":"Hao Wu","orcid":"https://orcid.org/0000-0003-2340-9258"},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Wu","raw_affiliation_strings":["College of Information Engineering, Northwest A&F University, Yangling, 712100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Information Engineering, Northwest A&F University, Yangling, 712100, China","institution_ids":["https://openalex.org/I89652312"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100778782","display_name":"Shuqin Li","orcid":"https://orcid.org/0000-0003-3647-442X"},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shuqin Li","raw_affiliation_strings":["College of Information Engineering, Northwest A&F University, Yangling, 712100, China","Shaanxi Key Laboratory of Agricultural Information Perception and Intelligent Service, Yangling, Shaanxi 712100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Information Engineering, Northwest A&F University, Yangling, 712100, China","institution_ids":["https://openalex.org/I89652312"]},{"raw_affiliation_string":"Shaanxi Key Laboratory of Agricultural Information Perception and Intelligent Service, Yangling, Shaanxi 712100, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012709797","display_name":"Jiangning Song","orcid":"https://orcid.org/0000-0001-8031-9086"},"institutions":[{"id":"https://openalex.org/I4210146297","display_name":"ARC Centre of Excellence in Advanced Molecular Imaging","ror":"https://ror.org/051e7s436","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1337719021","https://openalex.org/I2801453606","https://openalex.org/I4210132349","https://openalex.org/I4210146297","https://openalex.org/I56590836"]},{"id":"https://openalex.org/I56590836","display_name":"Monash University","ror":"https://ror.org/02bfwt286","country_code":"AU","type":"education","lineage":["https://openalex.org/I56590836"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Jiangning Song","raw_affiliation_strings":["ARC Centre of Excellence in Advanced Molecular Imaging, Monash University, Melbourne, VIC 3800, Australia","Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC 3800, Australia","Monash Centre for Data Science, Monash University, Melbourne, VIC 3800, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ARC Centre of Excellence in Advanced Molecular Imaging, Monash University, Melbourne, VIC 3800, Australia","institution_ids":["https://openalex.org/I4210146297","https://openalex.org/I56590836"]},{"raw_affiliation_string":"Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC 3800, Australia","institution_ids":["https://openalex.org/I56590836"]},{"raw_affiliation_string":"Monash Centre for Data Science, Monash University, Melbourne, VIC 3800, Australia","institution_ids":["https://openalex.org/I56590836"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101569366","display_name":"Quanzhong Liu","orcid":"https://orcid.org/0000-0002-6217-6285"},"institutions":[{"id":"https://openalex.org/I89652312","display_name":"Northwest A&F University","ror":"https://ror.org/0051rme32","country_code":"CN","type":"education","lineage":["https://openalex.org/I89652312"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Quanzhong Liu","raw_affiliation_strings":["College of Information Engineering, Northwest A&F University, Yangling, 712100, China","Shaanxi Key Laboratory of Agricultural Information Perception and Intelligent Service, Yangling, Shaanxi 712100, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Information Engineering, Northwest A&F University, Yangling, 712100, China","institution_ids":["https://openalex.org/I89652312"]},{"raw_affiliation_string":"Shaanxi Key Laboratory of Agricultural Information Perception and Intelligent Service, Yangling, Shaanxi 712100, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5012709797","https://openalex.org/A5100778782","https://openalex.org/A5101569366"],"corresponding_institution_ids":["https://openalex.org/I4210146297","https://openalex.org/I56590836","https://openalex.org/I89652312"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":3.4309,"has_fulltext":false,"cited_by_count":105,"citation_normalized_percentile":{"value":0.94048961,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"22","issue":"4","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.994700014591217,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8052229881286621},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.6993749141693115},{"id":"https://openalex.org/keywords/feature-selection","display_name":"Feature selection","score":0.6482391357421875},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6215592622756958},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5095944404602051},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.5006699562072754},{"id":"https://openalex.org/keywords/benchmarking","display_name":"Benchmarking","score":0.4736258387565613},{"id":"https://openalex.org/keywords/ensemble-learning","display_name":"Ensemble learning","score":0.45431825518608093},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.45004427433013916},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.44529300928115845},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.432010293006897},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.07815584540367126}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8052229881286621},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.6993749141693115},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.6482391357421875},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6215592622756958},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5095944404602051},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.5006699562072754},{"id":"https://openalex.org/C86251818","wikidata":"https://www.wikidata.org/wiki/Q816754","display_name":"Benchmarking","level":2,"score":0.4736258387565613},{"id":"https://openalex.org/C45942800","wikidata":"https://www.wikidata.org/wiki/Q245652","display_name":"Ensemble learning","level":2,"score":0.45431825518608093},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.45004427433013916},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.44529300928115845},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.432010293006897},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.07815584540367126},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D010455","descriptor_name":"Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1093/bib/bbaa312","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbaa312","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33316035","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33316035","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null},{"id":"pmh:oai:digital.library.adelaide.edu.au:2440/139586","is_oa":false,"landing_page_url":"https://hdl.handle.net/2440/139586","pdf_url":null,"source":{"id":"https://openalex.org/S4306401835","display_name":"Adelaide Research & Scholarship (AR&S) (University of Adelaide)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I5681781","host_organization_name":"The University of Adelaide","host_organization_lineage":["https://openalex.org/I5681781"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://dx.doi.org/10.1093/bib/bbaa312","raw_type":"Journal article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8294543","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8294543","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:8294543","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8294543","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brief Bioinform","raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1127919792","display_name":"Stochastic modelling of telomere length regulation in ageing research","funder_award_id":"DP120104460","funder_id":"https://openalex.org/F4320334704","funder_display_name":"Australian Research Council"},{"id":"https://openalex.org/G241248248","display_name":"Characterisation of plant cysteine proteases with therapeutic potential","funder_award_id":"LP110200333","funder_id":"https://openalex.org/F4320334704","funder_display_name":"Australian Research Council"},{"id":"https://openalex.org/G5076668117","display_name":null,"funder_award_id":"R01 AI111965","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G715904284","display_name":"\u4e09\u7ef4\u57fa\u56e0\u7ec4\u8c03\u63a7\u5c42\u9762\u7684\u764c\u75c7\u81f4\u75c5\u901a\u8def\u6316\u6398\u65b9\u6cd5\u7814\u7a76","funder_award_id":"61972322","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7921690166","display_name":null,"funder_award_id":"R01 AI111965","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320320971","display_name":"Monash University","ror":"https://ror.org/02bfwt286"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334704","display_name":"Australian Research Council","ror":"https://ror.org/05mmh0f86"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":77,"referenced_works":["https://openalex.org/W572368116","https://openalex.org/W605727707","https://openalex.org/W1977241485","https://openalex.org/W1984020445","https://openalex.org/W1992450378","https://openalex.org/W1995757481","https://openalex.org/W2015490529","https://openalex.org/W2034070267","https://openalex.org/W2038681300","https://openalex.org/W2042619042","https://openalex.org/W2044573154","https://openalex.org/W2072026441","https://openalex.org/W2074196504","https://openalex.org/W2094403468","https://openalex.org/W2097606916","https://openalex.org/W2099153308","https://openalex.org/W2103525038","https://openalex.org/W2118911320","https://openalex.org/W2120026469","https://openalex.org/W2129115651","https://openalex.org/W2139709150","https://openalex.org/W2145957695","https://openalex.org/W2147454197","https://openalex.org/W2152365098","https://openalex.org/W2152800101","https://openalex.org/W2167917621","https://openalex.org/W2187089797","https://openalex.org/W2222575139","https://openalex.org/W2337731955","https://openalex.org/W2339719866","https://openalex.org/W2340970647","https://openalex.org/W2527519129","https://openalex.org/W2528774686","https://openalex.org/W2625609557","https://openalex.org/W2747758005","https://openalex.org/W2766389776","https://openalex.org/W2793168264","https://openalex.org/W2793278326","https://openalex.org/W2799462250","https://openalex.org/W2806146459","https://openalex.org/W2810225085","https://openalex.org/W2883467144","https://openalex.org/W2890951984","https://openalex.org/W2891164245","https://openalex.org/W2891420113","https://openalex.org/W2901754076","https://openalex.org/W2911188335","https://openalex.org/W2912678142","https://openalex.org/W2913961829","https://openalex.org/W2922210059","https://openalex.org/W2936599975","https://openalex.org/W2937145808","https://openalex.org/W2943935116","https://openalex.org/W2945375732","https://openalex.org/W2946682182","https://openalex.org/W2965679756","https://openalex.org/W2967960129","https://openalex.org/W2969086705","https://openalex.org/W2977235223","https://openalex.org/W2977291005","https://openalex.org/W2987660980","https://openalex.org/W2995915627","https://openalex.org/W2999580270","https://openalex.org/W3012898475","https://openalex.org/W3021404320","https://openalex.org/W3024086681","https://openalex.org/W3026425509","https://openalex.org/W3048086963","https://openalex.org/W4232478844","https://openalex.org/W4249920046","https://openalex.org/W6654483831","https://openalex.org/W6680606795","https://openalex.org/W6703930214","https://openalex.org/W6727623720","https://openalex.org/W6728150723","https://openalex.org/W6759104856","https://openalex.org/W6771801627"],"related_works":["https://openalex.org/W4238897586","https://openalex.org/W435179959","https://openalex.org/W2619091065","https://openalex.org/W2059640416","https://openalex.org/W1490753184","https://openalex.org/W2284465472","https://openalex.org/W2291782699","https://openalex.org/W1993948687","https://openalex.org/W2000169967","https://openalex.org/W2112883198"],"abstract_inverted_index":{"Anti-cancer":[0],"peptides":[1],"(ACPs)":[2],"are":[3,32],"known":[4],"as":[5,52],"potential":[6,196],"therapeutics":[7,79],"for":[8,60,131,156,198,213,250],"cancer.":[9],"Due":[10],"to":[11,15,82,116,140,179],"their":[12,96,161],"unique":[13],"ability":[14],"target":[16],"cancer":[17,81],"cells":[18,22],"without":[19],"affecting":[20],"healthy":[21],"directly,":[23],"they":[24],"have":[25,66],"been":[26,67],"extensively":[27],"studied.":[28],"Many":[29],"peptide-based":[30],"drugs":[31],"currently":[33],"evaluated":[34],"in":[35,49,61,90,93,147,158],"the":[36,72,75,118,123,132,181,186,199,214,224,240],"preclinical":[37],"and":[38,108,120,129,134,142,170,183,234,255,265],"clinical":[39],"trials.":[40],"Accurate":[41],"identification":[42,63,216],"of":[43,56,64,77,95,122,136,160,185,217,258],"ACPs":[44,65,78,157],"has":[45],"received":[46],"considerable":[47],"attention":[48],"recent":[50],"years;":[51],"such,":[53],"a":[54,87,190,206,247],"number":[55],"machine":[57,99],"learning-based":[58],"methods":[59,70,92,107,242],"silico":[62],"developed.":[68],"These":[69],"promote":[71],"research":[73],"on":[74,223],"mechanism":[76],"against":[80,239],"some":[83],"extent.":[84],"There":[85],"is":[86,114,177,220,260],"vast":[88],"difference":[89],"these":[91],"terms":[94,159],"training/testing":[97],"datasets,":[98],"learning":[100,209],"algorithms,":[101,163],"feature":[102,105,164],"encoding":[103,165],"schemes,":[104,166],"selection":[106],"evaluation":[109,168],"strategies":[110,197],"used.":[111],"Therefore,":[112],"it":[113],"desirable":[115],"summarize":[117],"advantages":[119],"disadvantages":[121],"existing":[124,187],"methods,":[125],"provide":[126,195],"useful":[127],"insights":[128],"suggestions":[130],"development":[133],"improvement":[135],"novel":[137,207],"computational":[138],"tools":[139],"characterize":[141],"identify":[143],"ACPs.":[144,218,252],"With":[145],"this":[146],"mind,":[148],"we":[149,204],"firstly":[150],"comprehensively":[151],"investigate":[152],"16":[153],"state-of-the-art":[154,241],"predictors":[155,188],"core":[162],"performance":[167,175,201,249],"metrics":[169],"webserver/software":[171],"usability.":[172],"Then,":[173],"comprehensive":[174],"assessment":[176],"conducted":[178],"evaluate":[180],"robustness":[182],"scalability":[184],"using":[189],"well-prepared":[191],"benchmark":[192],"dataset.":[193],"We":[194],"model":[200],"improvement.":[202],"Moreover,":[203],"propose":[205],"ensemble":[208,226],"framework,":[210],"termed":[211],"ACPredStackL,":[212],"accurate":[215],"ACPredStackL":[219,245,259],"developed":[221],"based":[222],"stacking":[225],"strategy":[227],"combined":[228],"with":[229],"SVM,":[230],"Na\u00efve":[231],"Bayesian,":[232],"lightGBM":[233],"KNN.":[235],"Empirical":[236],"benchmarking":[237],"experiments":[238],"demonstrate":[243],"that":[244],"achieves":[246],"comparative":[248],"predicting":[251],"The":[253],"webserver":[254],"source":[256],"code":[257],"freely":[261],"available":[262],"at":[263],"http://bigdata.biocie.cn/ACPredStackL/":[264],"https://github.com/liangxiaoq/ACPredStackL,":[266],"respectively.":[267]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":37},{"year":2023,"cited_by_count":14},{"year":2022,"cited_by_count":22},{"year":2021,"cited_by_count":10}],"updated_date":"2026-07-15T18:14:33.161393","created_date":"2025-10-10T00:00:00"}