{"id":"https://openalex.org/W3111471842","doi":"https://doi.org/10.1093/bib/bbaa311","title":"Clinical significance and immunogenomic landscape analyses of the immune cell signature based prognostic model for patients with breast cancer","display_name":"Clinical significance and immunogenomic landscape analyses of the immune cell signature based prognostic model for patients with breast cancer","publication_year":2020,"publication_date":"2020-10-14","ids":{"openalex":"https://openalex.org/W3111471842","doi":"https://doi.org/10.1093/bib/bbaa311","mag":"3111471842","pmid":"https://pubmed.ncbi.nlm.nih.gov/33302293"},"language":"en","primary_location":{"id":"doi:10.1093/bib/bbaa311","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbaa311","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100640301","display_name":"Shiyuan Wang","orcid":"https://orcid.org/0000-0002-5028-5839"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shiyuan Wang","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043807380","display_name":"Yuqiang Xiong","orcid":null},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuqiang Xiong","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101819733","display_name":"Qi Zhang","orcid":"https://orcid.org/0000-0003-0692-1815"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qi Zhang","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012353128","display_name":"Dongqing Su","orcid":"https://orcid.org/0000-0003-2101-1852"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dongqing Su","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101085303","display_name":"Chunlu Yu","orcid":null},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chunlu Yu","raw_affiliation_strings":["Public Health College, Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Public Health College, Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085429158","display_name":"Yiyin Cao","orcid":null},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yiyin Cao","raw_affiliation_strings":["Public Health College, Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Public Health College, Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011343666","display_name":"Yi Pan","orcid":"https://orcid.org/0000-0002-0725-5685"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yi Pan","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000700883","display_name":"Qianzi Lu","orcid":null},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qianzi Lu","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001300435","display_name":"Yongchun Zuo","orcid":"https://orcid.org/0000-0002-6065-7835"},"institutions":[{"id":"https://openalex.org/I190774190","display_name":"Mongolian University of Life Sciences","ror":"https://ror.org/04ycjft64","country_code":"MN","type":"education","lineage":["https://openalex.org/I190774190"]},{"id":"https://openalex.org/I2722730","display_name":"Inner Mongolia University","ror":"https://ror.org/0106qb496","country_code":"CN","type":"education","lineage":["https://openalex.org/I2722730"]}],"countries":["CN","MN"],"is_corresponding":true,"raw_author_name":"Yongchun Zuo","raw_affiliation_strings":["State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University"],"raw_orcid":"https://orcid.org/0000-0002-6065-7835","affiliations":[{"raw_affiliation_string":"State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, College of Life Sciences, Inner Mongolia University","institution_ids":["https://openalex.org/I190774190","https://openalex.org/I2722730"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057225835","display_name":"Lei Yang","orcid":"https://orcid.org/0000-0002-1133-9099"},"institutions":[{"id":"https://openalex.org/I156144747","display_name":"Harbin Medical University","ror":"https://ror.org/05jscf583","country_code":"CN","type":"education","lineage":["https://openalex.org/I156144747"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Lei Yang","raw_affiliation_strings":["College of Bioinformatics Science and Technology, Harbin Medical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Bioinformatics Science and Technology, Harbin Medical University","institution_ids":["https://openalex.org/I156144747"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":10,"corresponding_author_ids":["https://openalex.org/A5001300435","https://openalex.org/A5057225835"],"corresponding_institution_ids":["https://openalex.org/I156144747","https://openalex.org/I190774190","https://openalex.org/I2722730"],"apc_list":{"value":4011,"currency":"USD","value_usd":4011},"apc_paid":null,"fwci":8.2651,"has_fulltext":false,"cited_by_count":108,"citation_normalized_percentile":{"value":0.98302362,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"22","issue":"4","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.7786059379577637},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.7747576832771301},{"id":"https://openalex.org/keywords/nomogram","display_name":"Nomogram","score":0.7497892379760742},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.7323283553123474},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.656662106513977},{"id":"https://openalex.org/keywords/immunotherapy","display_name":"Immunotherapy","score":0.5968536138534546},{"id":"https://openalex.org/keywords/cohort","display_name":"Cohort","score":0.5837661027908325},{"id":"https://openalex.org/keywords/malignancy","display_name":"Malignancy","score":0.5336300730705261},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.49069225788116455},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.45670175552368164},{"id":"https://openalex.org/keywords/biomarker","display_name":"Biomarker","score":0.4239910840988159},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"Tumor microenvironment","score":0.42361217737197876},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.26722025871276855},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.08236914873123169}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7786059379577637},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.7747576832771301},{"id":"https://openalex.org/C34626388","wikidata":"https://www.wikidata.org/wiki/Q721129","display_name":"Nomogram","level":2,"score":0.7497892379760742},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.7323283553123474},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.656662106513977},{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.5968536138534546},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5837661027908325},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5336300730705261},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.49069225788116455},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.45670175552368164},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.4239910840988159},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.42361217737197876},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.26722025871276855},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08236914873123169},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016246","descriptor_name":"Lymphocytes, Tumor-Infiltrating","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016246","descriptor_name":"Lymphocytes, Tumor-Infiltrating","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D016246","descriptor_name":"Lymphocytes, Tumor-Infiltrating","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D018448","descriptor_name":"Models, Immunological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018448","descriptor_name":"Models, Immunological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018448","descriptor_name":"Models, Immunological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D059016","descriptor_name":"Tumor Microenvironment","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1093/bib/bbaa311","is_oa":false,"landing_page_url":"https://doi.org/10.1093/bib/bbaa311","pdf_url":null,"source":{"id":"https://openalex.org/S91767247","display_name":"Briefings in Bioinformatics","issn_l":"1467-5463","issn":["1467-5463","1477-4054"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in Bioinformatics","raw_type":"journal-article"},{"id":"pmid:33302293","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33302293","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Briefings in bioinformatics","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7300000190734863}],"awards":[{"id":"https://openalex.org/G3499448240","display_name":null,"funder_award_id":"LH2020C100","funder_id":"https://openalex.org/F4320323085","funder_display_name":"Natural Science Foundation of Heilongjiang Province"},{"id":"https://openalex.org/G8619683445","display_name":null,"funder_award_id":"32000473","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323085","display_name":"Natural Science Foundation of Heilongjiang Province","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":66,"referenced_works":["https://openalex.org/W1498931318","https://openalex.org/W1601821256","https://openalex.org/W1906698094","https://openalex.org/W1908864745","https://openalex.org/W1966107523","https://openalex.org/W1985987855","https://openalex.org/W1992468678","https://openalex.org/W2005895632","https://openalex.org/W2021733365","https://openalex.org/W2025738474","https://openalex.org/W2028433016","https://openalex.org/W2035618305","https://openalex.org/W2046505430","https://openalex.org/W2056828743","https://openalex.org/W2076356585","https://openalex.org/W2091415498","https://openalex.org/W2098683355","https://openalex.org/W2112316706","https://openalex.org/W2112434826","https://openalex.org/W2114104545","https://openalex.org/W2116634113","https://openalex.org/W2130430382","https://openalex.org/W2132413371","https://openalex.org/W2132619562","https://openalex.org/W2134539328","https://openalex.org/W2135046866","https://openalex.org/W2140628034","https://openalex.org/W2143523733","https://openalex.org/W2146512944","https://openalex.org/W2157076315","https://openalex.org/W2157840751","https://openalex.org/W2159707944","https://openalex.org/W2160450758","https://openalex.org/W2169353806","https://openalex.org/W2172358623","https://openalex.org/W2291298003","https://openalex.org/W2308639964","https://openalex.org/W2412980992","https://openalex.org/W2461271870","https://openalex.org/W2521963431","https://openalex.org/W2533508881","https://openalex.org/W2567668099","https://openalex.org/W2588416433","https://openalex.org/W2599245250","https://openalex.org/W2612805962","https://openalex.org/W2761575992","https://openalex.org/W2771978163","https://openalex.org/W2781525129","https://openalex.org/W2784448860","https://openalex.org/W2785803176","https://openalex.org/W2787835497","https://openalex.org/W2792135005","https://openalex.org/W2796207838","https://openalex.org/W2804841700","https://openalex.org/W2885091354","https://openalex.org/W2892597528","https://openalex.org/W2892951532","https://openalex.org/W2910579854","https://openalex.org/W2911188335","https://openalex.org/W2940010972","https://openalex.org/W2992466184","https://openalex.org/W2999417355","https://openalex.org/W3005889306","https://openalex.org/W3009386543","https://openalex.org/W6762653448","https://openalex.org/W6774181438"],"related_works":["https://openalex.org/W1970018641","https://openalex.org/W4226494765","https://openalex.org/W2063908487","https://openalex.org/W1993821226","https://openalex.org/W4233588653","https://openalex.org/W4200022043","https://openalex.org/W2112727616","https://openalex.org/W4296613612","https://openalex.org/W2884525857","https://openalex.org/W4322720888"],"abstract_inverted_index":{"Breast":[0],"cancer":[1,33,67,90,174],"is":[2],"one":[3],"of":[4,9,15,27,72,107,159],"the":[5,12,40,44,56,82,87,97,104,112,125,157],"most":[6],"common":[7],"types":[8],"cancers":[10],"and":[11,62,86,99,124,129,162,164],"leading":[13],"cause":[14],"death":[16],"from":[17],"malignancy":[18],"among":[19],"women":[20],"worldwide.":[21],"Tumor-infiltrating":[22],"lymphocytes":[23,42],"are":[24],"a":[25,48,149],"source":[26],"important":[28],"prognostic":[29,51,70,76,151],"biomarkers":[30],"for":[31,59,156,168],"breast":[32,66,173],"patients.":[34,68,175],"In":[35],"this":[36,73,108,142],"study,":[37],"based":[38],"on":[39,135],"tumor-infiltrating":[41,120],"in":[43,55,65,81,96,172],"tumor":[45],"immune":[46,118,121],"microenvironment,":[47],"risk":[49,60,74,113,143],"score":[50,75,144],"model":[52,77,145],"was":[53,78],"developed":[54],"training":[57,98],"cohort":[58],"stratification":[61],"prognosis":[63],"prediction":[64],"The":[69],"value":[71],"also":[79,94,132],"verified":[80],"two":[83],"testing":[84,100],"cohorts":[85,101],"TCGA":[88],"pan":[89],"cohort.":[91],"Nomograms":[92],"were":[93,131],"established":[95],"to":[102,127],"validate":[103],"clinical":[105,169],"use":[106],"model.":[109],"Relationships":[110],"between":[111],"score,":[114],"intrinsic":[115],"molecular":[116],"subtypes,":[117],"checkpoints,":[119],"cell":[122],"abundances":[123],"response":[126],"chemotherapy":[128,161],"immunotherapy":[130],"evaluated.":[133],"Based":[134],"these":[136],"results,":[137],"we":[138],"can":[139],"conclude":[140],"that":[141],"could":[146],"serve":[147],"as":[148],"robust":[150],"biomarker,":[152],"provide":[153],"therapeutic":[154],"benefits":[155],"development":[158],"novel":[160],"immunotherapy,":[163],"may":[165],"be":[166],"helpful":[167],"decision":[170],"making":[171]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":20},{"year":2023,"cited_by_count":26},{"year":2022,"cited_by_count":33},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":2}],"updated_date":"2026-05-21T09:19:25.381259","created_date":"2025-10-10T00:00:00"}