{"id":"https://openalex.org/W4282923450","doi":"https://doi.org/10.1089/brain.2021.0157","title":"Changes in the Cerebello-Thalamo-Cortical Network After Magnetic Resonance-Guided Focused Ultrasound Thalamotomy","display_name":"Changes in the Cerebello-Thalamo-Cortical Network After Magnetic Resonance-Guided Focused Ultrasound Thalamotomy","publication_year":2022,"publication_date":"2022-06-09","ids":{"openalex":"https://openalex.org/W4282923450","doi":"https://doi.org/10.1089/brain.2021.0157","pmid":"https://pubmed.ncbi.nlm.nih.gov/35678063"},"language":"en","primary_location":{"id":"doi:10.1089/brain.2021.0157","is_oa":false,"landing_page_url":"https://doi.org/10.1089/brain.2021.0157","pdf_url":null,"source":{"id":"https://openalex.org/S2764941518","display_name":"Brain Connectivity","issn_l":"2158-0014","issn":["2158-0014","2158-0022"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Connectivity","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9942176/pdf/brain.2021.0157.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001955282","display_name":"Christian Thaler","orcid":"https://orcid.org/0000-0002-7102-9316"},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["DE","US"],"is_corresponding":true,"raw_author_name":"Christian Thaler","raw_affiliation_strings":["Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany","Department of Radiology, Stanford University, Stanford, California, USA"],"raw_orcid":"https://orcid.org/0000-0002-7102-9316","affiliations":[{"raw_affiliation_string":"Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"Department of Radiology, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066843175","display_name":"Qiyuan Tian","orcid":"https://orcid.org/0000-0002-8350-5295"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210127055","display_name":"Athinoula A. Martinos Center for Biomedical Imaging","ror":"https://ror.org/032q5ym94","country_code":"US","type":"facility","lineage":["https://openalex.org/I136199984","https://openalex.org/I4210087915","https://openalex.org/I4210127055","https://openalex.org/I48633490","https://openalex.org/I63966007"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Qiyuan Tian","raw_affiliation_strings":["Department of Electrical Engineering, Stanford University, Stanford, California, USA","Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA","Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA","Department of Radiology, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I4210127055"]},{"raw_affiliation_string":"Department of Radiology, Harvard Medical School, Boston, Massachusetts, USA","institution_ids":["https://openalex.org/I136199984"]},{"raw_affiliation_string":"Department of Radiology, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052087773","display_name":"Max Wintermark","orcid":"https://orcid.org/0000-0002-6726-3951"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Max Wintermark","raw_affiliation_strings":["Department of Radiology, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000304926","display_name":"Pejman Ghanouni","orcid":"https://orcid.org/0000-0002-6393-0964"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pejman Ghanouni","raw_affiliation_strings":["Department of Radiology, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083415417","display_name":"Casey H. Halpern","orcid":"https://orcid.org/0000-0003-3907-216X"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Casey H. Halpern","raw_affiliation_strings":["Department of Neurosurgery, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009856256","display_name":"Jaimie M. Henderson","orcid":"https://orcid.org/0000-0002-3276-2267"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jaimie M. Henderson","raw_affiliation_strings":["Department of Neurosurgery, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022335287","display_name":"Raag D. Airan","orcid":"https://orcid.org/0000-0001-5259-5606"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raag D. Airan","raw_affiliation_strings":["Department of Radiology, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002024060","display_name":"Michael Zeineh","orcid":"https://orcid.org/0000-0002-6940-9096"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Zeineh","raw_affiliation_strings":["Department of Radiology, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056005902","display_name":"Maged Goubran","orcid":"https://orcid.org/0000-0001-5880-0818"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maged Goubran","raw_affiliation_strings":["Department of Radiology, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068194964","display_name":"Christoph Leuze","orcid":"https://orcid.org/0000-0003-4564-8014"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christoph Leuze","raw_affiliation_strings":["Department of Radiology, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061175108","display_name":"Jens Fiehler","orcid":"https://orcid.org/0000-0001-8533-7478"},"institutions":[{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jens Fiehler","raw_affiliation_strings":["Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Kim Butts Pauly","orcid":null},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kim Butts Pauly","raw_affiliation_strings":["Department of Electrical Engineering, Stanford University, Stanford, California, USA","Department of Radiology, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical Engineering, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Department of Radiology, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5062751557","display_name":"Jennifer A. McNab","orcid":"https://orcid.org/0000-0002-1763-0792"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer A. McNab","raw_affiliation_strings":["Department of Radiology, Stanford University, Stanford, California, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Stanford University, Stanford, California, USA","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5001955282","https://openalex.org/A5066843175"],"corresponding_institution_ids":["https://openalex.org/I136199984","https://openalex.org/I159176309","https://openalex.org/I4210087915","https://openalex.org/I4210108711","https://openalex.org/I4210127055","https://openalex.org/I97018004"],"apc_list":null,"apc_paid":null,"fwci":1.4257,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.82700168,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"13","issue":"1","first_page":"28","last_page":"38"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11304","display_name":"Advanced Neuroimaging Techniques and Applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thalamotomy","display_name":"Thalamotomy","score":0.7985214591026306},{"id":"https://openalex.org/keywords/diffusion-mri","display_name":"Diffusion MRI","score":0.722195029258728},{"id":"https://openalex.org/keywords/fractional-anisotropy","display_name":"Fractional anisotropy","score":0.6708049774169922},{"id":"https://openalex.org/keywords/essential-tremor","display_name":"Essential tremor","score":0.5970727205276489},{"id":"https://openalex.org/keywords/corticospinal-tract","display_name":"Corticospinal tract","score":0.5849682688713074},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"Magnetic resonance imaging","score":0.5752373337745667},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4911041259765625},{"id":"https://openalex.org/keywords/white-matter","display_name":"White matter","score":0.444158136844635},{"id":"https://openalex.org/keywords/tractography","display_name":"Tractography","score":0.4415279030799866},{"id":"https://openalex.org/keywords/nuclear-medicine","display_name":"Nuclear medicine","score":0.431330144405365},{"id":"https://openalex.org/keywords/pyramidal-tracts","display_name":"Pyramidal tracts","score":0.42799919843673706},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.3716418147087097},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.3277943730354309},{"id":"https://openalex.org/keywords/physical-medicine-and-rehabilitation","display_name":"Physical medicine and rehabilitation","score":0.19528573751449585},{"id":"https://openalex.org/keywords/parkinsons-disease","display_name":"Parkinson's disease","score":0.1782831847667694},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.16308262944221497},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.09633755683898926},{"id":"https://openalex.org/keywords/deep-brain-stimulation","display_name":"Deep brain stimulation","score":0.08776795864105225}],"concepts":[{"id":"https://openalex.org/C2775841352","wikidata":"https://www.wikidata.org/wiki/Q1772023","display_name":"Thalamotomy","level":5,"score":0.7985214591026306},{"id":"https://openalex.org/C149550507","wikidata":"https://www.wikidata.org/wiki/Q899360","display_name":"Diffusion MRI","level":3,"score":0.722195029258728},{"id":"https://openalex.org/C89916169","wikidata":"https://www.wikidata.org/wiki/Q17014600","display_name":"Fractional anisotropy","level":4,"score":0.6708049774169922},{"id":"https://openalex.org/C2780112193","wikidata":"https://www.wikidata.org/wiki/Q693519","display_name":"Essential tremor","level":2,"score":0.5970727205276489},{"id":"https://openalex.org/C2779779279","wikidata":"https://www.wikidata.org/wiki/Q19915308","display_name":"Corticospinal tract","level":4,"score":0.5849682688713074},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.5752373337745667},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4911041259765625},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.444158136844635},{"id":"https://openalex.org/C84787856","wikidata":"https://www.wikidata.org/wiki/Q3076659","display_name":"Tractography","level":4,"score":0.4415279030799866},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.431330144405365},{"id":"https://openalex.org/C2778583998","wikidata":"https://www.wikidata.org/wiki/Q968731","display_name":"Pyramidal tracts","level":2,"score":0.42799919843673706},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3716418147087097},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3277943730354309},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.19528573751449585},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.1782831847667694},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.16308262944221497},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.09633755683898926},{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.08776795864105225},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014202","descriptor_name":"Tremor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014202","descriptor_name":"Tremor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014202","descriptor_name":"Tremor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014202","descriptor_name":"Tremor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020329","descriptor_name":"Essential Tremor","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D020329","descriptor_name":"Essential Tremor","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D020329","descriptor_name":"Essential Tremor","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D020329","descriptor_name":"Essential Tremor","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D020329","descriptor_name":"Essential Tremor","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D020329","descriptor_name":"Essential Tremor","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D020329","descriptor_name":"Essential Tremor","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D020329","descriptor_name":"Essential Tremor","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056324","descriptor_name":"Diffusion Tensor Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1089/brain.2021.0157","is_oa":false,"landing_page_url":"https://doi.org/10.1089/brain.2021.0157","pdf_url":null,"source":{"id":"https://openalex.org/S2764941518","display_name":"Brain Connectivity","issn_l":"2158-0014","issn":["2158-0014","2158-0022"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Connectivity","raw_type":"journal-article"},{"id":"pmid:35678063","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/35678063","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain connectivity","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9942176","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9942176","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9942176/pdf/brain.2021.0157.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brain Connect","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:9942176","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9942176","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9942176/pdf/brain.2021.0157.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Brain Connect","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7400000095367432,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1504471852","display_name":null,"funder_award_id":"R01NS095985","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G1535246123","display_name":"Integration of Advanced Diffusion MRI and 3D Histology for Improved Neurosurgical Targeting","funder_award_id":"2r01ns095985-04a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2036358624","display_name":null,"funder_award_id":"P41-EB015891","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G358049434","display_name":null,"funder_award_id":"R01MH/111444","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G376371285","display_name":null,"funder_award_id":"S10 RR026351","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G3990740972","display_name":"Training and Dissemination","funder_award_id":"5p41eb015891-25","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G669025608","display_name":null,"funder_award_id":"TH 2235/1-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G7288184987","display_name":null,"funder_award_id":"R01MH/111444","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8334758219","display_name":"Next Generation 7T MRI Platform Upgrade with Parallel Transmit Capabilities","funder_award_id":"1s10rr026351-01a1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320309171","display_name":"Focused Ultrasound Foundation","ror":"https://ror.org/04qjbd269"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4282923450.pdf","grobid_xml":"https://content.openalex.org/works/W4282923450.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1976901839","https://openalex.org/W1995604247","https://openalex.org/W2005495240","https://openalex.org/W2008655880","https://openalex.org/W2025162361","https://openalex.org/W2026752633","https://openalex.org/W2031012798","https://openalex.org/W2039861760","https://openalex.org/W2062436542","https://openalex.org/W2063001897","https://openalex.org/W2073956340","https://openalex.org/W2091910928","https://openalex.org/W2107956652","https://openalex.org/W2113682105","https://openalex.org/W2117987496","https://openalex.org/W2119177807","https://openalex.org/W2131979090","https://openalex.org/W2136145485","https://openalex.org/W2139267748","https://openalex.org/W2157192500","https://openalex.org/W2168445584","https://openalex.org/W2517769867","https://openalex.org/W2537797682","https://openalex.org/W2590552552","https://openalex.org/W2592940266","https://openalex.org/W2593946404","https://openalex.org/W2604465905","https://openalex.org/W2604621060","https://openalex.org/W2737966001","https://openalex.org/W2765093840","https://openalex.org/W2765156562","https://openalex.org/W2766790529","https://openalex.org/W2775672813","https://openalex.org/W2781303375","https://openalex.org/W2790291981","https://openalex.org/W2791991822","https://openalex.org/W2800619871","https://openalex.org/W2920974414","https://openalex.org/W2934400003","https://openalex.org/W2977883299","https://openalex.org/W3005723313","https://openalex.org/W3103756113","https://openalex.org/W3212346033"],"related_works":["https://openalex.org/W4225005357","https://openalex.org/W4391804798","https://openalex.org/W2943593955","https://openalex.org/W2613895879","https://openalex.org/W2738045572","https://openalex.org/W4232352638","https://openalex.org/W4387044589","https://openalex.org/W4237839515","https://openalex.org/W3013115952","https://openalex.org/W2028797269"],"abstract_inverted_index":{"Objective:":[0],"In":[1],"recent":[2],"years,":[3],"transcranial":[4],"magnetic":[5,81],"resonance-guided":[6],"focused":[7,332,363],"ultrasound":[8,333,364],"(tcMRgFUS)":[9],"has":[10],"been":[11],"established":[12],"as":[13,105,107],"a":[14,232],"potential":[15],"treatment":[16,308,372],"option":[17],"for":[18,98,236,361],"movement":[19],"disorders,":[20],"including":[21,86,151],"essential":[22],"tremor":[23],"(ET).":[24],"So":[25],"far,":[26],"however,":[27],"little":[28],"is":[29,295],"known":[30],"about":[31],"the":[32,94,103,111,120,124,128,165,168,184,189,192,203,237,245,277,299,307,325,340,355,371],"impact":[33],"of":[34,41,177,199,241,302,318,357,374],"tcMRgFUS":[35,61,73],"on":[36,134,191],"structural":[37,87],"connectivity.":[38],"The":[39,174,316],"objective":[40],"this":[42,72,319],"study":[43,320],"was":[44,100,116,234],"to":[45,118,142,297,312,369],"detect":[46,298],"microstructural":[47,300,322,337],"changes":[48,240,273,283,323,338],"in":[49,56,71,131,167,188],"tremor-":[50],"and":[51,88,93,127,158,170,187,247,281,310],"motor-related":[52],"white":[53],"matter":[54],"tracts":[55,166],"ET":[57,68],"patients":[58,65],"treated":[59,193],"with":[60,67,207,286,345],"thalamotomy.":[62,334],"Methods:":[63],"Eleven":[64],"diagnosed":[66],"were":[69,91,140,162,274],"enrolled":[70],"thalamotomy":[74,365],"study.":[75],"For":[76],"each":[77],"patient,":[78],"3":[79],"Tesla":[80],"resonance":[82],"imaging":[83,148],"(3T":[84],"MRI)":[85],"diffusion":[89,144,293],"MRI":[90,114,294],"acquired":[92],"Clinical":[95],"Rating":[96],"Scale":[97],"Tremor":[99],"assessed":[101],"before":[102],"procedure":[104],"well":[106,206,285],"1":[108,328],"year":[109,329],"after":[110,279,330],"treatment.":[112],"Diffusion":[113,146],"tractography":[115,138],"performed":[117],"identify":[119],"cerebello-thalamo-cortical":[121,326,341],"tract":[122,130],"(CTCT),":[123],"medial":[125],"lemniscus,":[126],"corticospinal":[129],"both":[132],"hemispheres":[133],"pre-treatment":[135],"data.":[136,145,172],"Pre-treatment":[137],"results":[139,290,317],"co-registered":[141],"post-treatment":[143,171],"tensor":[147],"(DTI)":[149],"metrics,":[150],"fractional":[152],"anisotropy":[153],"(FA),":[154],"mean":[155,175],"diffusivity":[156,160],"(MD)":[157],"radial":[159],"(RD),":[161],"averaged":[163],"across":[164],"pre-":[169],"Results:":[173],"value":[176],"tract-specific":[178],"DTI":[179],"metrics":[180],"changed":[181],"significantly":[182,344],"within":[183,202,244,276,324,339],"thalamic":[185],"lesion":[186,208],"CTCT":[190,204,246,278],"side":[194],"(p":[195],"<":[196],"0.05).":[197],"Changes":[198],"DTI-derived":[200,242],"indices":[201,243],"correlated":[205,284,343],"overlap":[209],"(FA:":[210,250],"r":[211,218,225,251,258,265],"=":[212,215,219,222,226,229,252,255,259,262,266,269],"\u22120.54,":[213],"p":[214,221,228,254,261,268],"0.04;":[216],"MD:":[217,257],"0.57,":[220],"0.04);":[223],"RD:":[224,264],"0.67,":[227],"0.036).":[230],"Further,":[231],"trend":[233],"seen":[235],"correlation":[238],"between":[239],"clinical":[248,346],"improvement":[249],"0.58;":[253],"0.062;":[256],"\u22120.52,":[260],"0.64;":[263],"\u22120.61":[267],"0.090).":[270],"Conclusions:":[271],"Microstructural":[272],"detected":[275],"tcMRgFUS,":[280,303],"these":[282],"lesion-tract":[287],"overlap.":[288],"Our":[289],"show":[291],"that":[292],"able":[296],"effects":[301],"thereby":[304],"further":[305],"elucidating":[306],"mechanism,":[309],"ultimately":[311],"improve":[313],"targeting":[314,359],"prospectively.":[315],"demonstrate":[321],"pathways":[327,342],"MR-guided":[331,362],"Even":[335],"more,":[336],"outcome.":[347],"These":[348],"findings":[349],"do":[350],"not":[351],"only":[352],"highly":[353],"emphasize":[354],"need":[356],"new":[358],"strategies":[360],"but":[366],"also":[367],"help":[368],"elucidate":[370],"mechanism":[373],"it.":[375]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":2}],"updated_date":"2026-08-25T07:29:55.448023","created_date":"2025-10-10T00:00:00"}