{"id":"https://openalex.org/W2057705283","doi":"https://doi.org/10.1089/big.2012.1505","title":"Unraveling the Complexities of Life Sciences Data","display_name":"Unraveling the Complexities of Life Sciences Data","publication_year":2012,"publication_date":"2012-11-07","ids":{"openalex":"https://openalex.org/W2057705283","doi":"https://doi.org/10.1089/big.2012.1505","mag":"2057705283","pmid":"https://pubmed.ncbi.nlm.nih.gov/27447037"},"language":"en","primary_location":{"id":"doi:10.1089/big.2012.1505","is_oa":false,"landing_page_url":"https://doi.org/10.1089/big.2012.1505","pdf_url":null,"source":{"id":"https://openalex.org/S4210226731","display_name":"Big Data","issn_l":"2167-6461","issn":["2167-6461","2167-647X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443"],"host_organization_lineage_names":["Mary Ann Liebert, Inc."],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Big Data","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108222756","display_name":"Roger Higdon","orcid":null},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I2802617771","display_name":"Health Alliance International","ror":"https://ror.org/022c13n15","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I201448701","https://openalex.org/I2802617771"]},{"id":"https://openalex.org/I4210127406","display_name":"Alliance Data (United States)","ror":"https://ror.org/02gzaeb51","country_code":"US","type":"company","lineage":["https://openalex.org/I4210127406"]},{"id":"https://openalex.org/I4210151837","display_name":"High Throughput Biology (United States)","ror":"https://ror.org/05h1bjp83","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151837"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roger Higdon","raw_affiliation_strings":["Data-Enabled Life Sciences Alliance (DELSA Global)","Seattle Children's","Seattle Children's Research Institute","Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","Predictive Analytics, Seattle Children's, Seattle, Washington","High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington"],"affiliations":[{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global)","institution_ids":["https://openalex.org/I4210127406"]},{"raw_affiliation_string":"Seattle Children's","institution_ids":["https://openalex.org/I1295499534"]},{"raw_affiliation_string":"Seattle Children's Research Institute","institution_ids":[]},{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","institution_ids":["https://openalex.org/I2802617771"]},{"raw_affiliation_string":"Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]},{"raw_affiliation_string":"Predictive Analytics, Seattle Children's, Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022202018","display_name":"Winston Haynes","orcid":"https://orcid.org/0000-0002-2376-0630"},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I2802617771","display_name":"Health Alliance International","ror":"https://ror.org/022c13n15","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I201448701","https://openalex.org/I2802617771"]},{"id":"https://openalex.org/I4210127406","display_name":"Alliance Data (United States)","ror":"https://ror.org/02gzaeb51","country_code":"US","type":"company","lineage":["https://openalex.org/I4210127406"]},{"id":"https://openalex.org/I4210151837","display_name":"High Throughput Biology (United States)","ror":"https://ror.org/05h1bjp83","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151837"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Winston Haynes","raw_affiliation_strings":["Data-Enabled Life Sciences Alliance (DELSA Global)","Seattle Children's","Seattle Children's Research Institute","Predictive Analytics, Seattle Children's, Seattle, Washington","Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington"],"affiliations":[{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global)","institution_ids":["https://openalex.org/I4210127406"]},{"raw_affiliation_string":"Seattle Children's","institution_ids":["https://openalex.org/I1295499534"]},{"raw_affiliation_string":"Seattle Children's Research Institute","institution_ids":[]},{"raw_affiliation_string":"Predictive Analytics, Seattle Children's, Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]},{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","institution_ids":["https://openalex.org/I2802617771"]},{"raw_affiliation_string":"High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068385320","display_name":"Larissa Stanberry","orcid":"https://orcid.org/0000-0002-2388-0640"},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I2802617771","display_name":"Health Alliance International","ror":"https://ror.org/022c13n15","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I201448701","https://openalex.org/I2802617771"]},{"id":"https://openalex.org/I4210127406","display_name":"Alliance Data (United States)","ror":"https://ror.org/02gzaeb51","country_code":"US","type":"company","lineage":["https://openalex.org/I4210127406"]},{"id":"https://openalex.org/I4210151837","display_name":"High Throughput Biology (United States)","ror":"https://ror.org/05h1bjp83","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151837"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Larissa Stanberry","raw_affiliation_strings":["Data-Enabled Life Sciences Alliance (DELSA Global)","Seattle Children's","Seattle Children's Research Institute","Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","Predictive Analytics, Seattle Children's, Seattle, Washington","High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington"],"affiliations":[{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global)","institution_ids":["https://openalex.org/I4210127406"]},{"raw_affiliation_string":"Seattle Children's","institution_ids":["https://openalex.org/I1295499534"]},{"raw_affiliation_string":"Seattle Children's Research Institute","institution_ids":[]},{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","institution_ids":["https://openalex.org/I2802617771"]},{"raw_affiliation_string":"Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]},{"raw_affiliation_string":"Predictive Analytics, Seattle Children's, Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064747721","display_name":"Elizabeth Stewart","orcid":"https://orcid.org/0000-0002-9366-9138"},"institutions":[{"id":"https://openalex.org/I2802617771","display_name":"Health Alliance International","ror":"https://ror.org/022c13n15","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I201448701","https://openalex.org/I2802617771"]},{"id":"https://openalex.org/I4210127406","display_name":"Alliance Data (United States)","ror":"https://ror.org/02gzaeb51","country_code":"US","type":"company","lineage":["https://openalex.org/I4210127406"]},{"id":"https://openalex.org/I4210151837","display_name":"High Throughput Biology (United States)","ror":"https://ror.org/05h1bjp83","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151837"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeth Stewart","raw_affiliation_strings":["Data-Enabled Life Sciences Alliance (DELSA Global)","Seattle Children's Research Institute","Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington"],"affiliations":[{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global)","institution_ids":["https://openalex.org/I4210127406"]},{"raw_affiliation_string":"Seattle Children's Research Institute","institution_ids":[]},{"raw_affiliation_string":"Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]},{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","institution_ids":["https://openalex.org/I2802617771"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043688719","display_name":"Gregory Yandl","orcid":null},"institutions":[{"id":"https://openalex.org/I2802617771","display_name":"Health Alliance International","ror":"https://ror.org/022c13n15","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I201448701","https://openalex.org/I2802617771"]},{"id":"https://openalex.org/I4210127406","display_name":"Alliance Data (United States)","ror":"https://ror.org/02gzaeb51","country_code":"US","type":"company","lineage":["https://openalex.org/I4210127406"]},{"id":"https://openalex.org/I4210151837","display_name":"High Throughput Biology (United States)","ror":"https://ror.org/05h1bjp83","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151837"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory Yandl","raw_affiliation_strings":["Data-Enabled Life Sciences Alliance (DELSA Global)","Seattle Children's Research Institute","Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington","Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington"],"affiliations":[{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global)","institution_ids":["https://openalex.org/I4210127406"]},{"raw_affiliation_string":"Seattle Children's Research Institute","institution_ids":[]},{"raw_affiliation_string":"Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]},{"raw_affiliation_string":"High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]},{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","institution_ids":["https://openalex.org/I2802617771"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073650344","display_name":"Chris Howard","orcid":"https://orcid.org/0000-0002-6061-0826"},"institutions":[{"id":"https://openalex.org/I2802617771","display_name":"Health Alliance International","ror":"https://ror.org/022c13n15","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I201448701","https://openalex.org/I2802617771"]},{"id":"https://openalex.org/I4210127406","display_name":"Alliance Data (United States)","ror":"https://ror.org/02gzaeb51","country_code":"US","type":"company","lineage":["https://openalex.org/I4210127406"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chris Howard","raw_affiliation_strings":["Data-Enabled Life Sciences Alliance (DELSA Global)","Seattle Children's Research Institute","Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington"],"affiliations":[{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global)","institution_ids":["https://openalex.org/I4210127406"]},{"raw_affiliation_string":"Seattle Children's Research Institute","institution_ids":[]},{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","institution_ids":["https://openalex.org/I2802617771"]},{"raw_affiliation_string":"Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056533315","display_name":"William Broomall","orcid":null},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I2802617771","display_name":"Health Alliance International","ror":"https://ror.org/022c13n15","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I201448701","https://openalex.org/I2802617771"]},{"id":"https://openalex.org/I4210127406","display_name":"Alliance Data (United States)","ror":"https://ror.org/02gzaeb51","country_code":"US","type":"company","lineage":["https://openalex.org/I4210127406"]},{"id":"https://openalex.org/I4210151837","display_name":"High Throughput Biology (United States)","ror":"https://ror.org/05h1bjp83","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151837"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William Broomall","raw_affiliation_strings":["Data-Enabled Life Sciences Alliance (DELSA Global)","Seattle Children's","Seattle Children's Research Institute","Predictive Analytics, Seattle Children's, Seattle, Washington","Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington"],"affiliations":[{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global)","institution_ids":["https://openalex.org/I4210127406"]},{"raw_affiliation_string":"Seattle Children's","institution_ids":["https://openalex.org/I1295499534"]},{"raw_affiliation_string":"Seattle Children's Research Institute","institution_ids":[]},{"raw_affiliation_string":"Predictive Analytics, Seattle Children's, Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","institution_ids":["https://openalex.org/I2802617771"]},{"raw_affiliation_string":"High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026653925","display_name":"Natali Kolker","orcid":null},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I2802617771","display_name":"Health Alliance International","ror":"https://ror.org/022c13n15","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I201448701","https://openalex.org/I2802617771"]},{"id":"https://openalex.org/I4210127406","display_name":"Alliance Data (United States)","ror":"https://ror.org/02gzaeb51","country_code":"US","type":"company","lineage":["https://openalex.org/I4210127406"]},{"id":"https://openalex.org/I4210151837","display_name":"High Throughput Biology (United States)","ror":"https://ror.org/05h1bjp83","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151837"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Natali Kolker","raw_affiliation_strings":["Data-Enabled Life Sciences Alliance (DELSA Global)","Seattle Children's","Seattle Children's Research Institute","Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington","Predictive Analytics, Seattle Children's, Seattle, Washington"],"affiliations":[{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global)","institution_ids":["https://openalex.org/I4210127406"]},{"raw_affiliation_string":"Seattle Children's","institution_ids":["https://openalex.org/I1295499534"]},{"raw_affiliation_string":"Seattle Children's Research Institute","institution_ids":[]},{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","institution_ids":["https://openalex.org/I2802617771"]},{"raw_affiliation_string":"High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]},{"raw_affiliation_string":"Predictive Analytics, Seattle Children's, Seattle, Washington","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087861388","display_name":"Eugene Kolker","orcid":null},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]},{"id":"https://openalex.org/I2801852214","display_name":"University of Washington Medical Center","ror":"https://ror.org/00wbzw723","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801852214"]},{"id":"https://openalex.org/I2802617771","display_name":"Health Alliance International","ror":"https://ror.org/022c13n15","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I201448701","https://openalex.org/I2802617771"]},{"id":"https://openalex.org/I4210127406","display_name":"Alliance Data (United States)","ror":"https://ror.org/02gzaeb51","country_code":"US","type":"company","lineage":["https://openalex.org/I4210127406"]},{"id":"https://openalex.org/I4210151837","display_name":"High Throughput Biology (United States)","ror":"https://ror.org/05h1bjp83","country_code":"US","type":"company","lineage":["https://openalex.org/I4210151837"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eugene Kolker","raw_affiliation_strings":["Data-Enabled Life Sciences Alliance (DELSA Global)","Seattle Children's","Seattle Children's Research Institute","University of Washington","Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","Departments of Biomedical Informatics & Medical Education and Pediatrics, University of Washington, Seattle, Washington","Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","Predictive Analytics, Seattle Children's, Seattle, Washington","High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington"],"affiliations":[{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global)","institution_ids":["https://openalex.org/I4210127406"]},{"raw_affiliation_string":"Seattle Children's","institution_ids":["https://openalex.org/I1295499534"]},{"raw_affiliation_string":"Seattle Children's Research Institute","institution_ids":[]},{"raw_affiliation_string":"University of Washington","institution_ids":["https://openalex.org/I201448701"]},{"raw_affiliation_string":"Bioinformatics and High-throughput Analysis Laboratory, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]},{"raw_affiliation_string":"Departments of Biomedical Informatics & Medical Education and Pediatrics, University of Washington, Seattle, Washington","institution_ids":["https://openalex.org/I2801852214"]},{"raw_affiliation_string":"Data-Enabled Life Sciences Alliance (DELSA Global), Seattle, Washington","institution_ids":["https://openalex.org/I2802617771"]},{"raw_affiliation_string":"Predictive Analytics, Seattle Children's, Seattle, Washington","institution_ids":[]},{"raw_affiliation_string":"High-throughput Analysis Core, Center for Developmental Therapeutics, Seattle Children's Research Institute, Seattle, Washington","institution_ids":["https://openalex.org/I4210151837"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5087861388"],"corresponding_institution_ids":["https://openalex.org/I1295499534","https://openalex.org/I201448701","https://openalex.org/I2801852214","https://openalex.org/I2802617771","https://openalex.org/I4210127406","https://openalex.org/I4210151837"],"apc_list":null,"apc_paid":null,"fwci":2.6819,"has_fulltext":false,"cited_by_count":49,"citation_normalized_percentile":{"value":0.9046589,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"1","issue":"1","first_page":"42","last_page":"50"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications","score":0.9889000058174133,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.7172300815582275},{"id":"https://openalex.org/keywords/big-data","display_name":"Big data","score":0.6214888691902161},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5822651386260986},{"id":"https://openalex.org/keywords/variety","display_name":"Variety (cybernetics)","score":0.5807398557662964},{"id":"https://openalex.org/keywords/biological-data","display_name":"Biological data","score":0.4830073118209839},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.4687899053096771},{"id":"https://openalex.org/keywords/resource","display_name":"Resource (disambiguation)","score":0.4610298275947571},{"id":"https://openalex.org/keywords/data-integration","display_name":"Data integration","score":0.4444376230239868},{"id":"https://openalex.org/keywords/cloud-computing","display_name":"Cloud computing","score":0.437865287065506},{"id":"https://openalex.org/keywords/implementation","display_name":"Implementation","score":0.43345585465431213},{"id":"https://openalex.org/keywords/data-management","display_name":"Data management","score":0.42372092604637146},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.2195957899093628},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.1611703336238861},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.13259917497634888},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11827769875526428},{"id":"https://openalex.org/keywords/software-engineering","display_name":"Software engineering","score":0.10064801573753357}],"concepts":[{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.7172300815582275},{"id":"https://openalex.org/C75684735","wikidata":"https://www.wikidata.org/wiki/Q858810","display_name":"Big data","level":2,"score":0.6214888691902161},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5822651386260986},{"id":"https://openalex.org/C136197465","wikidata":"https://www.wikidata.org/wiki/Q1729295","display_name":"Variety (cybernetics)","level":2,"score":0.5807398557662964},{"id":"https://openalex.org/C201797286","wikidata":"https://www.wikidata.org/wiki/Q4914986","display_name":"Biological data","level":2,"score":0.4830073118209839},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.4687899053096771},{"id":"https://openalex.org/C206345919","wikidata":"https://www.wikidata.org/wiki/Q20380951","display_name":"Resource (disambiguation)","level":2,"score":0.4610298275947571},{"id":"https://openalex.org/C72634772","wikidata":"https://www.wikidata.org/wiki/Q386824","display_name":"Data integration","level":2,"score":0.4444376230239868},{"id":"https://openalex.org/C79974875","wikidata":"https://www.wikidata.org/wiki/Q483639","display_name":"Cloud computing","level":2,"score":0.437865287065506},{"id":"https://openalex.org/C26713055","wikidata":"https://www.wikidata.org/wiki/Q245962","display_name":"Implementation","level":2,"score":0.43345585465431213},{"id":"https://openalex.org/C1668388","wikidata":"https://www.wikidata.org/wiki/Q1149776","display_name":"Data management","level":2,"score":0.42372092604637146},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.2195957899093628},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.1611703336238861},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.13259917497634888},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11827769875526428},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.10064801573753357},{"id":"https://openalex.org/C31258907","wikidata":"https://www.wikidata.org/wiki/Q1301371","display_name":"Computer network","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1089/big.2012.1505","is_oa":false,"landing_page_url":"https://doi.org/10.1089/big.2012.1505","pdf_url":null,"source":{"id":"https://openalex.org/S4210226731","display_name":"Big Data","issn_l":"2167-6461","issn":["2167-6461","2167-647X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443"],"host_organization_lineage_names":["Mary Ann Liebert, Inc."],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Big Data","raw_type":"journal-article"},{"id":"pmid:27447037","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/27447037","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Big data","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","score":0.46000000834465027,"display_name":"Partnerships for the goals"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":92,"referenced_works":["https://openalex.org/W1526857120","https://openalex.org/W1542719686","https://openalex.org/W1966792579","https://openalex.org/W1968436111","https://openalex.org/W1974316742","https://openalex.org/W1979196241","https://openalex.org/W1984160169","https://openalex.org/W1987777080","https://openalex.org/W1990073900","https://openalex.org/W1993647605","https://openalex.org/W1996763260","https://openalex.org/W1997140139","https://openalex.org/W2002458103","https://openalex.org/W2003647795","https://openalex.org/W2008270505","https://openalex.org/W2014328430","https://openalex.org/W2017409020","https://openalex.org/W2017608260","https://openalex.org/W2019227019","https://openalex.org/W2020755839","https://openalex.org/W2021920388","https://openalex.org/W2024799741","https://openalex.org/W2028567538","https://openalex.org/W2035575075","https://openalex.org/W2038743372","https://openalex.org/W2039261408","https://openalex.org/W2042604928","https://openalex.org/W2050160299","https://openalex.org/W2050451112","https://openalex.org/W2052087727","https://openalex.org/W2055701877","https://openalex.org/W2055736116","https://openalex.org/W2059133370","https://openalex.org/W2063159471","https://openalex.org/W2064190604","https://openalex.org/W2065783627","https://openalex.org/W2075729202","https://openalex.org/W2076048958","https://openalex.org/W2076735582","https://openalex.org/W2079859830","https://openalex.org/W2080347313","https://openalex.org/W2081294880","https://openalex.org/W2083188317","https://openalex.org/W2084115201","https://openalex.org/W2086528005","https://openalex.org/W2091821191","https://openalex.org/W2093666160","https://openalex.org/W2093850775","https://openalex.org/W2098425296","https://openalex.org/W2104120081","https://openalex.org/W2116027790","https://openalex.org/W2116128039","https://openalex.org/W2119738171","https://openalex.org/W2120725895","https://openalex.org/W2122822084","https://openalex.org/W2130358901","https://openalex.org/W2130406402","https://openalex.org/W2131399825","https://openalex.org/W2134367256","https://openalex.org/W2136439301","https://openalex.org/W2136704415","https://openalex.org/W2137488129","https://openalex.org/W2141868008","https://openalex.org/W2145262276","https://openalex.org/W2146827656","https://openalex.org/W2147714160","https://openalex.org/W2151186216","https://openalex.org/W2154364831","https://openalex.org/W2155606054","https://openalex.org/W2156467546","https://openalex.org/W2156923894","https://openalex.org/W2158520060","https://openalex.org/W2159482845","https://openalex.org/W2159874791","https://openalex.org/W2161062388","https://openalex.org/W2167244132","https://openalex.org/W2168413498","https://openalex.org/W2169328938","https://openalex.org/W2169877598","https://openalex.org/W2170014507","https://openalex.org/W2173213060","https://openalex.org/W2186813747","https://openalex.org/W2410049139","https://openalex.org/W2620485168","https://openalex.org/W2912046302","https://openalex.org/W3126065083","https://openalex.org/W3144526075","https://openalex.org/W4205350350","https://openalex.org/W4213060373","https://openalex.org/W4239419596","https://openalex.org/W4252737679","https://openalex.org/W4255355434"],"related_works":["https://openalex.org/W2307569040","https://openalex.org/W2366067673","https://openalex.org/W2060096282","https://openalex.org/W2131941936","https://openalex.org/W2541393756","https://openalex.org/W2385643360","https://openalex.org/W4375944314","https://openalex.org/W2167730203","https://openalex.org/W1906884313","https://openalex.org/W3120201329"],"abstract_inverted_index":{"The":[0],"life":[1,181],"sciences":[2],"have":[3,177],"entered":[4],"into":[5,111,142],"the":[6,24,27,53,82,95,112,135,143,173,180,184,187],"realm":[7],"of":[8,26,30,85,98,116,120,122,128,134,154,159],"big":[9,31],"data":[10,15,22,64,77,156,176,188],"and":[11,37,41,66,94,118,132,157,169,192],"data-enabled":[12],"science,":[13],"where":[14],"can":[16],"either":[17],"empower":[18],"or":[19],"overwhelm.":[20],"These":[21],"bring":[23,190],"challenges":[25,65],"5":[28],"Vs":[29],"data:":[32],"volume,":[33],"veracity,":[34],"velocity,":[35],"variety,":[36],"value.":[38],"Both":[39],"independently":[40],"through":[42,125],"our":[43,147,149],"involvement":[44],"with":[45,146],"DELSA":[46],"Global":[47],"(Data-Enabled":[48],"Life":[49],"Sciences":[50],"Alliance,":[51],"DELSAglobal.org),":[52],"Kolker":[54],"Lab":[55],"(":[56],"kolkerlab.org":[57],")":[58,93],"is":[59,151],"creating":[60],"partnerships":[61],"that":[62],"identify":[63],"solve":[67],"community":[68,83],"needs.":[69],"We":[70],"specialize":[71],"in":[72,186],"solutions":[73,171],"to":[74,167,172,179],"complex":[75],"biological":[76,160],"challenges,":[78],"as":[79,162,164],"exemplified":[80],"by":[81],"resource":[84],"MOPED":[86],"(Model":[87],"Organism":[88],"Protein":[89,101,136],"Expression":[90],"Database,":[91],"MOPED.proteinspire.org":[92],"analysis":[96,117],"pipeline":[97],"SPIRE":[99],"(Systematic":[100],"Investigative":[102],"Research":[103],"Environment,":[104],"PROTEINSPIRE.org":[105],").":[106],"Our":[107],"collaborative":[108],"work":[109],"extends":[110],"computationally":[113],"intensive":[114],"tasks":[115],"visualization":[119],"millions":[121],"protein":[123],"sequences":[124],"innovative":[126],"implementations":[127],"sequence":[129],"alignment":[130],"algorithms":[131],"creation":[133],"Sequence":[137],"Universe":[138],"tool":[139],"(PSU).":[140],"Pushing":[141],"future":[144],"together":[145],"collaborators,":[148],"lab":[150],"pursuing":[152],"integration":[153],"multi-omics":[155],"exploration":[158],"pathways,":[161],"well":[163],"assigning":[165],"function":[166],"proteins":[168],"porting":[170],"cloud.":[174],"Big":[175],"come":[178],"sciences;":[182],"discovering":[183],"knowledge":[185],"will":[189],"breakthroughs":[191],"benefits.":[193]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":8}],"updated_date":"2026-03-13T14:20:09.374765","created_date":"2025-10-10T00:00:00"}