{"id":"https://openalex.org/W4362633463","doi":"https://doi.org/10.1080/21681163.2023.2197086","title":"Segmentation of cervical nuclei using convolutional neural network for conventional cytology","display_name":"Segmentation of cervical nuclei using convolutional neural network for conventional cytology","publication_year":2023,"publication_date":"2023-04-05","ids":{"openalex":"https://openalex.org/W4362633463","doi":"https://doi.org/10.1080/21681163.2023.2197086"},"language":"en","primary_location":{"id":"doi:10.1080/21681163.2023.2197086","is_oa":false,"landing_page_url":"https://doi.org/10.1080/21681163.2023.2197086","pdf_url":null,"source":{"id":"https://openalex.org/S2764763012","display_name":"Computer Methods in Biomechanics and Biomedical Engineering Imaging & Visualization","issn_l":"2168-1163","issn":["2168-1163","2168-1171"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045411426","display_name":"J\u00falia Beatriz A. Teixeira","orcid":null},"institutions":[{"id":"https://openalex.org/I10824318","display_name":"Universidade Federal de Ouro Preto","ror":"https://ror.org/056s65p46","country_code":"BR","type":"education","lineage":["https://openalex.org/I10824318"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"J\u00falia Beatriz A. Teixeira","raw_affiliation_strings":["Departamento de Computa\u00e7\u00e3o, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil"],"affiliations":[{"raw_affiliation_string":"Departamento de Computa\u00e7\u00e3o, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil","institution_ids":["https://openalex.org/I10824318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021316241","display_name":"Mariana T. Rezende","orcid":"https://orcid.org/0000-0002-9514-9312"},"institutions":[{"id":"https://openalex.org/I10824318","display_name":"Universidade Federal de Ouro Preto","ror":"https://ror.org/056s65p46","country_code":"BR","type":"education","lineage":["https://openalex.org/I10824318"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Mariana T. Rezende","raw_affiliation_strings":["Departamento de An\u00e1lises Cl\u00ednicas, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil"],"affiliations":[{"raw_affiliation_string":"Departamento de An\u00e1lises Cl\u00ednicas, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil","institution_ids":["https://openalex.org/I10824318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018693324","display_name":"D\u00e9bora N. Diniz","orcid":"https://orcid.org/0000-0002-1951-8868"},"institutions":[{"id":"https://openalex.org/I10824318","display_name":"Universidade Federal de Ouro Preto","ror":"https://ror.org/056s65p46","country_code":"BR","type":"education","lineage":["https://openalex.org/I10824318"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"D\u00e9bora N. Diniz","raw_affiliation_strings":["Departamento de Computa\u00e7\u00e3o, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil"],"affiliations":[{"raw_affiliation_string":"Departamento de Computa\u00e7\u00e3o, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil","institution_ids":["https://openalex.org/I10824318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046030524","display_name":"Cl\u00e1udia Martins Carneiro","orcid":"https://orcid.org/0000-0002-6002-857X"},"institutions":[{"id":"https://openalex.org/I10824318","display_name":"Universidade Federal de Ouro Preto","ror":"https://ror.org/056s65p46","country_code":"BR","type":"education","lineage":["https://openalex.org/I10824318"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Cl\u00e1udia M. Carneiro","raw_affiliation_strings":["Departamento de An\u00e1lises Cl\u00ednicas, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil"],"affiliations":[{"raw_affiliation_string":"Departamento de An\u00e1lises Cl\u00ednicas, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil","institution_ids":["https://openalex.org/I10824318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015475283","display_name":"Eduardo Luz","orcid":"https://orcid.org/0000-0001-5249-1559"},"institutions":[{"id":"https://openalex.org/I10824318","display_name":"Universidade Federal de Ouro Preto","ror":"https://ror.org/056s65p46","country_code":"BR","type":"education","lineage":["https://openalex.org/I10824318"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Eduardo J. da S. Luz","raw_affiliation_strings":["Departamento de Computa\u00e7\u00e3o, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil"],"affiliations":[{"raw_affiliation_string":"Departamento de Computa\u00e7\u00e3o, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil","institution_ids":["https://openalex.org/I10824318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006915301","display_name":"Marcone Jamilson Freitas Souza","orcid":"https://orcid.org/0000-0002-7141-357X"},"institutions":[{"id":"https://openalex.org/I10824318","display_name":"Universidade Federal de Ouro Preto","ror":"https://ror.org/056s65p46","country_code":"BR","type":"education","lineage":["https://openalex.org/I10824318"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"Marcone J. F. Souza","raw_affiliation_strings":["Departamento de Computa\u00e7\u00e3o, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil"],"affiliations":[{"raw_affiliation_string":"Departamento de Computa\u00e7\u00e3o, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil","institution_ids":["https://openalex.org/I10824318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050276927","display_name":"Daniela Ushizima","orcid":"https://orcid.org/0000-0002-7363-9468"},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniela M. Ushizima","raw_affiliation_strings":["Department of Energy, University of California - Berkeley, Berkeley CA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Energy, University of California - Berkeley, Berkeley CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018707025","display_name":"F\u00e1tima N. S. de Medeiros","orcid":"https://orcid.org/0000-0003-3075-8771"},"institutions":[{"id":"https://openalex.org/I243754102","display_name":"Universidade Federal do Cear\u00e1","ror":"https://ror.org/03srtnf24","country_code":"BR","type":"education","lineage":["https://openalex.org/I243754102"]}],"countries":["BR"],"is_corresponding":false,"raw_author_name":"F\u00e1tima N. S. de Medeiros","raw_affiliation_strings":["Departamento de Engenharia de Teleinform\u00e1tica, Universidade Federal do Cear\u00e1, Fortaleza, CE, Brazil"],"affiliations":[{"raw_affiliation_string":"Departamento de Engenharia de Teleinform\u00e1tica, Universidade Federal do Cear\u00e1, Fortaleza, CE, Brazil","institution_ids":["https://openalex.org/I243754102"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040077481","display_name":"Andrea Bianchi","orcid":"https://orcid.org/0000-0001-7949-1188"},"institutions":[{"id":"https://openalex.org/I10824318","display_name":"Universidade Federal de Ouro Preto","ror":"https://ror.org/056s65p46","country_code":"BR","type":"education","lineage":["https://openalex.org/I10824318"]}],"countries":["BR"],"is_corresponding":true,"raw_author_name":"Andrea G. Campos Bianchi","raw_affiliation_strings":["Departamento de Computa\u00e7\u00e3o, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil"],"affiliations":[{"raw_affiliation_string":"Departamento de Computa\u00e7\u00e3o, Universidade Federal de Ouro Preto, Ouro Preto-MG, Brazil","institution_ids":["https://openalex.org/I10824318"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5040077481"],"corresponding_institution_ids":["https://openalex.org/I10824318"],"apc_list":null,"apc_paid":null,"fwci":0.8908,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.78203917,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"11","issue":"5","first_page":"1876","last_page":"1888"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10146","display_name":"Cervical Cancer and HPV Research","score":0.9908000230789185,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12874","display_name":"Digital Imaging for Blood Diseases","score":0.9733999967575073,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.636101484298706},{"id":"https://openalex.org/keywords/convolutional-neural-network","display_name":"Convolutional neural network","score":0.6193678379058838},{"id":"https://openalex.org/keywords/false-positive-paradox","display_name":"False positive paradox","score":0.6033908128738403},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.5796762704849243},{"id":"https://openalex.org/keywords/cytology","display_name":"Cytology","score":0.5298397541046143},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5152176022529602},{"id":"https://openalex.org/keywords/cervical-cancer","display_name":"Cervical cancer","score":0.49743083119392395},{"id":"https://openalex.org/keywords/cervix","display_name":"Cervix","score":0.4751703143119812},{"id":"https://openalex.org/keywords/automation","display_name":"Automation","score":0.47365033626556396},{"id":"https://openalex.org/keywords/s\u00f8rensen\u2013dice-coefficient","display_name":"S\u00f8rensen\u2013Dice coefficient","score":0.45493870973587036},{"id":"https://openalex.org/keywords/dice","display_name":"Dice","score":0.41124504804611206},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4005398154258728},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.308870404958725},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.2498045265674591},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.15916645526885986},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.14337092638015747},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.12115165591239929},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.1076829731464386},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.10198241472244263}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.636101484298706},{"id":"https://openalex.org/C81363708","wikidata":"https://www.wikidata.org/wiki/Q17084460","display_name":"Convolutional neural network","level":2,"score":0.6193678379058838},{"id":"https://openalex.org/C64869954","wikidata":"https://www.wikidata.org/wiki/Q1859747","display_name":"False positive paradox","level":2,"score":0.6033908128738403},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.5796762704849243},{"id":"https://openalex.org/C18823058","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cytology","level":2,"score":0.5298397541046143},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5152176022529602},{"id":"https://openalex.org/C2778220009","wikidata":"https://www.wikidata.org/wiki/Q160105","display_name":"Cervical cancer","level":3,"score":0.49743083119392395},{"id":"https://openalex.org/C2777740455","wikidata":"https://www.wikidata.org/wiki/Q666412","display_name":"Cervix","level":3,"score":0.4751703143119812},{"id":"https://openalex.org/C115901376","wikidata":"https://www.wikidata.org/wiki/Q184199","display_name":"Automation","level":2,"score":0.47365033626556396},{"id":"https://openalex.org/C163892561","wikidata":"https://www.wikidata.org/wiki/Q2613728","display_name":"S\u00f8rensen\u2013Dice coefficient","level":4,"score":0.45493870973587036},{"id":"https://openalex.org/C22029948","wikidata":"https://www.wikidata.org/wiki/Q45089","display_name":"Dice","level":2,"score":0.41124504804611206},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4005398154258728},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.308870404958725},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2498045265674591},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.15916645526885986},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.14337092638015747},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.12115165591239929},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1076829731464386},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.10198241472244263},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1080/21681163.2023.2197086","is_oa":false,"landing_page_url":"https://doi.org/10.1080/21681163.2023.2197086","pdf_url":null,"source":{"id":"https://openalex.org/S2764763012","display_name":"Computer Methods in Biomechanics and Biomedical Engineering Imaging & Visualization","issn_l":"2168-1163","issn":["2168-1163","2168-1171"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8799999952316284,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G8181033481","display_name":null,"funder_award_id":"905103/2020","funder_id":"https://openalex.org/F4320322836","funder_display_name":"Ministry of Health, British Columbia"}],"funders":[{"id":"https://openalex.org/F4320306084","display_name":"U.S. Department of Energy","ror":"https://ror.org/01bj3aw27"},{"id":"https://openalex.org/F4320322836","display_name":"Ministry of Health, British Columbia","ror":"https://ror.org/05smbmp94"},{"id":"https://openalex.org/F4320332359","display_name":"Office of Science","ror":"https://ror.org/00mmn6b08"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1901129140","https://openalex.org/W2155813740","https://openalex.org/W2161381512","https://openalex.org/W2343237073","https://openalex.org/W2412782625","https://openalex.org/W2474583162","https://openalex.org/W2549139847","https://openalex.org/W2561675875","https://openalex.org/W2606147825","https://openalex.org/W2728813321","https://openalex.org/W2734583741","https://openalex.org/W2790916948","https://openalex.org/W2887280559","https://openalex.org/W2890567626","https://openalex.org/W2912449434","https://openalex.org/W2932122572","https://openalex.org/W2963200645","https://openalex.org/W2964309882","https://openalex.org/W2969980243","https://openalex.org/W2980633381","https://openalex.org/W3009289191","https://openalex.org/W3009901339","https://openalex.org/W3015258803","https://openalex.org/W3015870511","https://openalex.org/W3020678160","https://openalex.org/W3026868384","https://openalex.org/W3033728548","https://openalex.org/W3099661372","https://openalex.org/W3124470488","https://openalex.org/W3126624898","https://openalex.org/W3161285534","https://openalex.org/W3169873017","https://openalex.org/W3171746194","https://openalex.org/W3183269049","https://openalex.org/W4225923070"],"related_works":["https://openalex.org/W3104750253","https://openalex.org/W3021239166","https://openalex.org/W4402926319","https://openalex.org/W4389060404","https://openalex.org/W2973136608","https://openalex.org/W3012828488","https://openalex.org/W4286233748","https://openalex.org/W4254054209","https://openalex.org/W4200334192","https://openalex.org/W2952835238"],"abstract_inverted_index":{"Although":[0],"implementing":[1],"the":[2,8,21,24,27,33,39,44,77,155,162,166],"Pap":[3],"smear":[4],"has":[5],"drastically":[6],"reduced":[7],"mortality":[9],"rates":[10],"from":[11,105],"cervical":[12,89,141],"cancer,":[13],"false":[14],"positives":[15],"and":[16,26,62,81,100,108,125,150],"negatives":[17],"are":[18],"related":[19],"to":[20,42,70],"quality":[22,40],"of":[23,35,59,79,121,136,140,148,157,161],"analysis":[25,164],"cytopathologist":[28],"experience.":[29],"An":[30],"alternative":[31],"is":[32,49],"insertion":[34],"digital":[36],"cytology":[37,48,112],"in":[38,88,146,165],"monitoring":[41],"assist":[43],"screening.":[45],"However,":[46],"conventional":[47],"still":[50],"a":[51,57,118,133],"major":[52],"challenge,":[53],"as":[54,159],"it":[55,68],"presents":[56],"lot":[58],"cellular":[60],"overlap":[61,149],"several":[63],"epithelial":[64],"structures":[65],"that":[66],"make":[67],"difficult":[69],"implement":[71],"computational":[72],"methodologies.":[73],"This":[74],"article":[75],"compares":[76],"performance":[78],"U-net":[80],"SegNet":[82],"neural":[83],"networks":[84],"for":[85,123,127],"nuclei":[86,142],"segmentation":[87],"images.":[90],"Experiments":[91],"were":[92],"performed":[93],"with":[94,143],"different":[95],"activation":[96],"functions,":[97],"batch":[98],"sizes,":[99],"datasets,":[101],"ISBI":[102],"(synthetic":[103],"images":[104,139],"liquid":[106],"cytology)":[107],"CRIC":[109,128],"Cervix-Seg":[110],"(conventional":[111],"real":[113,138],"images).":[114],"The":[115],"models":[116],"achieved":[117],"Dice":[119],"coefficient":[120],"0.9783":[122],"ISBI2015":[124],"0.9429":[126],"Cervix-Seg.":[129],"These":[130],"results":[131],"suggest":[132],"methodology":[134],"capable":[135],"segmenting":[137],"quality,":[144],"even":[145],"situations":[147],"artefacts,":[151],"advancing":[152],"efforts":[153],"towards":[154],"automation":[156],"tasks":[158],"part":[160],"cytopathological":[163],"laboratory":[167],"work":[168],"routine.":[169]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-03-08T08:50:53.379069","created_date":"2025-10-10T00:00:00"}