{"id":"https://openalex.org/W3186466455","doi":"https://doi.org/10.1080/21681163.2021.1956370","title":"3D FEM model to simulate Brownian motion inside trabecular tissue from human femoral head","display_name":"3D FEM model to simulate Brownian motion inside trabecular tissue from human femoral head","publication_year":2021,"publication_date":"2021-07-26","ids":{"openalex":"https://openalex.org/W3186466455","doi":"https://doi.org/10.1080/21681163.2021.1956370","mag":"3186466455"},"language":"en","primary_location":{"id":"doi:10.1080/21681163.2021.1956370","is_oa":false,"landing_page_url":"https://doi.org/10.1080/21681163.2021.1956370","pdf_url":null,"source":{"id":"https://openalex.org/S2764763012","display_name":"Computer Methods in Biomechanics and Biomedical Engineering Imaging & Visualization","issn_l":"2168-1163","issn":["2168-1163","2168-1171"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5069478037","display_name":"Fabiano Bini","orcid":"https://orcid.org/0000-0002-5641-1189"},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Fabiano Bini","raw_affiliation_strings":["Department of Mechanical and Aerospace Engineering, \u201cSapienza\u201d University of Rome, Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, \u201cSapienza\u201d University of Rome, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051266645","display_name":"Andrada Pica","orcid":"https://orcid.org/0000-0002-6877-4120"},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrada Pica","raw_affiliation_strings":["Department of Mechanical and Aerospace Engineering, \u201cSapienza\u201d University of Rome, Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, \u201cSapienza\u201d University of Rome, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033836407","display_name":"Simone Novelli","orcid":"https://orcid.org/0000-0003-2797-8925"},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]}],"countries":["GB","IT"],"is_corresponding":false,"raw_author_name":"Simone Novelli","raw_affiliation_strings":["Department of Mechanical and Aerospace Engineering, \u201cSapienza\u201d University of Rome, Rome, Italy","Institute for Liver and Digestive Health, University College London (UCL), London, UK"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, \u201cSapienza\u201d University of Rome, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]},{"raw_affiliation_string":"Institute for Liver and Digestive Health, University College London (UCL), London, UK","institution_ids":["https://openalex.org/I45129253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047760828","display_name":"Raffaella Pecci","orcid":"https://orcid.org/0000-0002-6500-9124"},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Raffaella Pecci","raw_affiliation_strings":["National Centre of Innovative Technologies in Public Health, Istituto Superiore Di Sanit\u00e0, Rome, Italy"],"affiliations":[{"raw_affiliation_string":"National Centre of Innovative Technologies in Public Health, Istituto Superiore Di Sanit\u00e0, Rome, Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055424652","display_name":"R. Bedini","orcid":null},"institutions":[{"id":"https://openalex.org/I27897274","display_name":"Istituto Superiore di Sanit\u00e0","ror":"https://ror.org/02hssy432","country_code":"IT","type":"government","lineage":["https://openalex.org/I27897274"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rossella Bedini","raw_affiliation_strings":["National Centre of Innovative Technologies in Public Health, Istituto Superiore Di Sanit\u00e0, Rome, Italy"],"affiliations":[{"raw_affiliation_string":"National Centre of Innovative Technologies in Public Health, Istituto Superiore Di Sanit\u00e0, Rome, Italy","institution_ids":["https://openalex.org/I27897274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022898960","display_name":"Andrea Marinozzi","orcid":"https://orcid.org/0000-0002-4631-9151"},"institutions":[{"id":"https://openalex.org/I155125353","display_name":"Universit\u00e0 Campus Bio-Medico","ror":"https://ror.org/04gqx4x78","country_code":"IT","type":"education","lineage":["https://openalex.org/I155125353"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Marinozzi","raw_affiliation_strings":["Orthopedy and Traumatology Area, \u201cCampus Bio-Medico\u201d University, Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Orthopedy and Traumatology Area, \u201cCampus Bio-Medico\u201d University, Rome, Italy","institution_ids":["https://openalex.org/I155125353"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024333391","display_name":"Franco Marinozzi","orcid":"https://orcid.org/0000-0002-4872-2980"},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Franco Marinozzi","raw_affiliation_strings":["Department of Mechanical and Aerospace Engineering, \u201cSapienza\u201d University of Rome, Rome, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Mechanical and Aerospace Engineering, \u201cSapienza\u201d University of Rome, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5069478037"],"corresponding_institution_ids":["https://openalex.org/I861853513"],"apc_list":null,"apc_paid":null,"fwci":0.3949,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.583451,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"10","issue":"5","first_page":"500","last_page":"507"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10264","display_name":"Asphalt Pavement Performance Evaluation","score":0.9933000206947327,"subfield":{"id":"https://openalex.org/subfields/2205","display_name":"Civil and Structural Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10264","display_name":"Asphalt Pavement Performance Evaluation","score":0.9933000206947327,"subfield":{"id":"https://openalex.org/subfields/2205","display_name":"Civil and Structural Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10716","display_name":"Soil and Unsaturated Flow","score":0.9909999966621399,"subfield":{"id":"https://openalex.org/subfields/2205","display_name":"Civil and Structural Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trabecular-bone","display_name":"Trabecular bone","score":0.7124539613723755},{"id":"https://openalex.org/keywords/cancellous-bone","display_name":"Cancellous bone","score":0.6714572906494141},{"id":"https://openalex.org/keywords/finite-element-method","display_name":"Finite element method","score":0.6514276266098022},{"id":"https://openalex.org/keywords/particle","display_name":"Particle (ecology)","score":0.5544643402099609},{"id":"https://openalex.org/keywords/mechanics","display_name":"Mechanics","score":0.4914659261703491},{"id":"https://openalex.org/keywords/diffusion","display_name":"Diffusion","score":0.46198612451553345},{"id":"https://openalex.org/keywords/brownian-motion","display_name":"Brownian motion","score":0.45125094056129456},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.42652034759521484},{"id":"https://openalex.org/keywords/head","display_name":"Head (geology)","score":0.4214448630809784},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.41460463404655457},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.3859522044658661},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3553588390350342},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2473239004611969},{"id":"https://openalex.org/keywords/geology","display_name":"Geology","score":0.22652855515480042},{"id":"https://openalex.org/keywords/anatomy","display_name":"Anatomy","score":0.1943587064743042},{"id":"https://openalex.org/keywords/acoustics","display_name":"Acoustics","score":0.14779210090637207},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.14129051566123962},{"id":"https://openalex.org/keywords/structural-engineering","display_name":"Structural engineering","score":0.12373441457748413}],"concepts":[{"id":"https://openalex.org/C3018268312","wikidata":"https://www.wikidata.org/wiki/Q2671642","display_name":"Trabecular bone","level":3,"score":0.7124539613723755},{"id":"https://openalex.org/C2776350087","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cancellous bone","level":2,"score":0.6714572906494141},{"id":"https://openalex.org/C135628077","wikidata":"https://www.wikidata.org/wiki/Q220184","display_name":"Finite element method","level":2,"score":0.6514276266098022},{"id":"https://openalex.org/C2778517922","wikidata":"https://www.wikidata.org/wiki/Q7140482","display_name":"Particle (ecology)","level":2,"score":0.5544643402099609},{"id":"https://openalex.org/C57879066","wikidata":"https://www.wikidata.org/wiki/Q41217","display_name":"Mechanics","level":1,"score":0.4914659261703491},{"id":"https://openalex.org/C69357855","wikidata":"https://www.wikidata.org/wiki/Q163214","display_name":"Diffusion","level":2,"score":0.46198612451553345},{"id":"https://openalex.org/C112401455","wikidata":"https://www.wikidata.org/wiki/Q178036","display_name":"Brownian motion","level":2,"score":0.45125094056129456},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.42652034759521484},{"id":"https://openalex.org/C2780312720","wikidata":"https://www.wikidata.org/wiki/Q5689100","display_name":"Head (geology)","level":2,"score":0.4214448630809784},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.41460463404655457},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.3859522044658661},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3553588390350342},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2473239004611969},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.22652855515480042},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.1943587064743042},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.14779210090637207},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.14129051566123962},{"id":"https://openalex.org/C66938386","wikidata":"https://www.wikidata.org/wiki/Q633538","display_name":"Structural engineering","level":1,"score":0.12373441457748413},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.0},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C114793014","wikidata":"https://www.wikidata.org/wiki/Q52109","display_name":"Geomorphology","level":1,"score":0.0},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.0},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1080/21681163.2021.1956370","is_oa":false,"landing_page_url":"https://doi.org/10.1080/21681163.2021.1956370","pdf_url":null,"source":{"id":"https://openalex.org/S2764763012","display_name":"Computer Methods in Biomechanics and Biomedical Engineering Imaging & Visualization","issn_l":"2168-1163","issn":["2168-1163","2168-1171"],"is_oa":false,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computer Methods in Biomechanics and Biomedical Engineering: Imaging & Visualization","raw_type":"journal-article"},{"id":"pmh:oai:iris.uniroma1.it:11573/1579650","is_oa":false,"landing_page_url":"https://hdl.handle.net/11573/1579650","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.800000011920929,"id":"https://metadata.un.org/sdg/6","display_name":"Clean water and sanitation"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1064607210","https://openalex.org/W1488940286","https://openalex.org/W1877580752","https://openalex.org/W1975613888","https://openalex.org/W1980863483","https://openalex.org/W1993288936","https://openalex.org/W2007220143","https://openalex.org/W2023218131","https://openalex.org/W2044651364","https://openalex.org/W2059633577","https://openalex.org/W2066646366","https://openalex.org/W2077921297","https://openalex.org/W2088170172","https://openalex.org/W2113938951","https://openalex.org/W2148453117","https://openalex.org/W2166079767","https://openalex.org/W2171759639","https://openalex.org/W2202919106","https://openalex.org/W2263556947","https://openalex.org/W2556028656","https://openalex.org/W2559774873","https://openalex.org/W2604604403","https://openalex.org/W2729724031","https://openalex.org/W2741550508","https://openalex.org/W2759839148","https://openalex.org/W2773740976","https://openalex.org/W2789343580","https://openalex.org/W2807635598","https://openalex.org/W2890216231","https://openalex.org/W2905632471","https://openalex.org/W2916196459","https://openalex.org/W2921397124","https://openalex.org/W2921687834","https://openalex.org/W2963872238","https://openalex.org/W2966213259","https://openalex.org/W2975919065","https://openalex.org/W3015705213","https://openalex.org/W4211160782"],"related_works":["https://openalex.org/W1657151843","https://openalex.org/W1618612856","https://openalex.org/W3155097668","https://openalex.org/W2601222103","https://openalex.org/W2019465331","https://openalex.org/W2951427856","https://openalex.org/W1672129004","https://openalex.org/W2763024822","https://openalex.org/W91110341","https://openalex.org/W2085696967"],"abstract_inverted_index":{"The":[0,51,80,121],"assessment":[1],"of":[2,5,25,41,45,59,88,112,130],"spatio-temporal":[3],"distribution":[4],"water":[6,46,60,90,100,113],"within":[7,93,102],"the":[8,17,39,43,57,85,89,94,99,103,109,128],"cancellous":[9],"bone":[10,49,119,132],"structure":[11],"remains":[12],"a":[13,20,26],"challenging":[14],"issue.":[15],"In":[16],"present":[18],"study,":[19],"3D":[21],"finite":[22],"element":[23],"model":[24,53,122],"trabecular":[27,95,118],"region":[28],"with":[29,38,134],"pore":[30],"morphology":[31,105],"reconstructed":[32,104],"from":[33,56],"micro-CT":[34],"scans":[35],"is":[36,71],"developed":[37],"aim":[40],"evaluating":[42],"dynamics":[44,76,101],"diffusion":[47,55],"through":[48],"tissue.":[50],"proposed":[52],"formulates":[54],"perspective":[58],"particles":[61],"motion.":[62],"Newton\u2019s":[63],"second":[64],"law":[65],"adapted":[66],"to":[67,73,83,107],"consider":[68],"Brownian":[69],"motion":[70],"used":[72],"describe":[74],"particle":[75,91],"in":[77],"Lagrangian":[78],"framework.":[79],"outcomes":[81],"allow":[82],"investigate":[84],"temporal":[86],"evolution":[87],"positions":[92],"network.":[96],"Knowledge":[97],"concerning":[98],"contributes":[106],"optimise":[108],"experimental":[110],"setup":[111],"uptake":[114],"investigations":[115],"on":[116],"specific":[117],"samples.":[120],"could":[123],"provide":[124],"valuable":[125],"information":[126],"for":[127],"design":[129],"mimetic":[131],"scaffolds":[133],"optimised":[135],"fluid":[136],"management":[137],"properties.":[138]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2021-08-02T00:00:00"}