{"id":"https://openalex.org/W4410716600","doi":"https://doi.org/10.1080/09540091.2025.2508357","title":"PSPNet EPO-SEB: a novel attention-enhanced hybrid model for accurate histopathological image segmentation","display_name":"PSPNet EPO-SEB: a novel attention-enhanced hybrid model for accurate histopathological image segmentation","publication_year":2025,"publication_date":"2025-05-24","ids":{"openalex":"https://openalex.org/W4410716600","doi":"https://doi.org/10.1080/09540091.2025.2508357"},"language":"en","primary_location":{"id":"doi:10.1080/09540091.2025.2508357","is_oa":true,"landing_page_url":"https://doi.org/10.1080/09540091.2025.2508357","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/09540091.2025.2508357?needAccess=true","source":{"id":"https://openalex.org/S4210188800","display_name":"Connection Science","issn_l":"0954-0091","issn":["0954-0091","1360-0494"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Connection Science","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.tandfonline.com/doi/pdf/10.1080/09540091.2025.2508357?needAccess=true","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015640979","display_name":"Prem Purusottam Jena","orcid":null},"institutions":[{"id":"https://openalex.org/I193073490","display_name":"Siksha O Anusandhan University","ror":"https://ror.org/056ep7w45","country_code":"IN","type":"education","lineage":["https://openalex.org/I193073490"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Prem Purusottam Jena","raw_affiliation_strings":["Siksha \u2018O\u2019 Anusandhan (Deemed to be University)","Department of Computer Science and Engineering, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Siksha \u2018O\u2019 Anusandhan (Deemed to be University)","institution_ids":["https://openalex.org/I193073490"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, India","institution_ids":["https://openalex.org/I193073490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108016465","display_name":"Debahuti Mishra","orcid":"https://orcid.org/0000-0002-6827-6121"},"institutions":[{"id":"https://openalex.org/I193073490","display_name":"Siksha O Anusandhan University","ror":"https://ror.org/056ep7w45","country_code":"IN","type":"education","lineage":["https://openalex.org/I193073490"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Debahuti Mishra","raw_affiliation_strings":["Siksha \u2018O\u2019 Anusandhan (Deemed to be University)","Department of Computer Science and Engineering, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Siksha \u2018O\u2019 Anusandhan (Deemed to be University)","institution_ids":["https://openalex.org/I193073490"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, India","institution_ids":["https://openalex.org/I193073490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004788462","display_name":"Kaberi Das","orcid":"https://orcid.org/0000-0002-4974-6300"},"institutions":[{"id":"https://openalex.org/I193073490","display_name":"Siksha O Anusandhan University","ror":"https://ror.org/056ep7w45","country_code":"IN","type":"education","lineage":["https://openalex.org/I193073490"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Kaberi Das","raw_affiliation_strings":["Department of Computer Application, Siksha \u2018O\u2019 Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India","Department of Computer Application, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Application, Siksha \u2018O\u2019 Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India","institution_ids":["https://openalex.org/I193073490"]},{"raw_affiliation_string":"Department of Computer Application, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India","institution_ids":["https://openalex.org/I193073490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085316306","display_name":"Sashikala Mishra","orcid":"https://orcid.org/0000-0002-5433-4917"},"institutions":[{"id":"https://openalex.org/I244572783","display_name":"Symbiosis International University","ror":"https://ror.org/005r2ww51","country_code":"IN","type":"education","lineage":["https://openalex.org/I244572783"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sashikala Mishra","raw_affiliation_strings":["Symbiosis International (Deemed to be) University","Department of Computer Science and Engineering, Symbiosis Institute of Technology, Symbiosis International (Deemed to be) University, Pune, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Symbiosis International (Deemed to be) University","institution_ids":["https://openalex.org/I244572783"]},{"raw_affiliation_string":"Department of Computer Science and Engineering, Symbiosis Institute of Technology, Symbiosis International (Deemed to be) University, Pune, India","institution_ids":["https://openalex.org/I244572783"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081109716","display_name":"Mandakini Priyadarshani Behera","orcid":"https://orcid.org/0000-0001-5930-9262"},"institutions":[{"id":"https://openalex.org/I67357951","display_name":"KIIT University","ror":"https://ror.org/00k8zt527","country_code":"IN","type":"education","lineage":["https://openalex.org/I67357951"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mandakini Priyadarshani Behera","raw_affiliation_strings":["KIIT Deemed to be University","School of Computer Engineering, KIIT Deemed to be University, Bhubaneswar, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"KIIT Deemed to be University","institution_ids":["https://openalex.org/I67357951"]},{"raw_affiliation_string":"School of Computer Engineering, KIIT Deemed to be University, Bhubaneswar, India","institution_ids":["https://openalex.org/I67357951"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015640979"],"corresponding_institution_ids":["https://openalex.org/I193073490"],"apc_list":{"value":1270,"currency":"USD","value_usd":1270},"apc_paid":{"value":1270,"currency":"USD","value_usd":1270},"fwci":1.396,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.83743509,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"37","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6656723022460938},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6355191469192505},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.5489228367805481},{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.537545919418335},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.5099812746047974},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.4942777156829834},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.4123415946960449}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6656723022460938},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6355191469192505},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.5489228367805481},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.537545919418335},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.5099812746047974},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.4942777156829834},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.4123415946960449}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1080/09540091.2025.2508357","is_oa":true,"landing_page_url":"https://doi.org/10.1080/09540091.2025.2508357","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/09540091.2025.2508357?needAccess=true","source":{"id":"https://openalex.org/S4210188800","display_name":"Connection Science","issn_l":"0954-0091","issn":["0954-0091","1360-0494"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Connection Science","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1080/09540091.2025.2508357","is_oa":true,"landing_page_url":"https://doi.org/10.1080/09540091.2025.2508357","pdf_url":"https://www.tandfonline.com/doi/pdf/10.1080/09540091.2025.2508357?needAccess=true","source":{"id":"https://openalex.org/S4210188800","display_name":"Connection Science","issn_l":"0954-0091","issn":["0954-0091","1360-0494"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Connection Science","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410716600.pdf","grobid_xml":"https://content.openalex.org/works/W4410716600.grobid-xml"},"referenced_works_count":58,"referenced_works":["https://openalex.org/W401943522","https://openalex.org/W2752782242","https://openalex.org/W2807821935","https://openalex.org/W2964741087","https://openalex.org/W3002798547","https://openalex.org/W3108513211","https://openalex.org/W3169911935","https://openalex.org/W3184090563","https://openalex.org/W3185052070","https://openalex.org/W4206693420","https://openalex.org/W4211121719","https://openalex.org/W4220896502","https://openalex.org/W4221165903","https://openalex.org/W4285061598","https://openalex.org/W4285135672","https://openalex.org/W4285505938","https://openalex.org/W4288077770","https://openalex.org/W4292415246","https://openalex.org/W4297942012","https://openalex.org/W4308366198","https://openalex.org/W4308946502","https://openalex.org/W4312297640","https://openalex.org/W4313478178","https://openalex.org/W4316661229","https://openalex.org/W4319300655","https://openalex.org/W4319987526","https://openalex.org/W4321350881","https://openalex.org/W4323309632","https://openalex.org/W4323841380","https://openalex.org/W4361829758","https://openalex.org/W4365453246","https://openalex.org/W4378221994","https://openalex.org/W4384519501","https://openalex.org/W4386069665","https://openalex.org/W4386608828","https://openalex.org/W4386824998","https://openalex.org/W4387033190","https://openalex.org/W4387247694","https://openalex.org/W4387350602","https://openalex.org/W4390204228","https://openalex.org/W4390502208","https://openalex.org/W4390577002","https://openalex.org/W4390659995","https://openalex.org/W4391697718","https://openalex.org/W4399618918","https://openalex.org/W4400229045","https://openalex.org/W4400310003","https://openalex.org/W4400314717","https://openalex.org/W4401235470","https://openalex.org/W4401326637","https://openalex.org/W4401559981","https://openalex.org/W4402062094","https://openalex.org/W4402282873","https://openalex.org/W4402445510","https://openalex.org/W4402558950","https://openalex.org/W4402580640","https://openalex.org/W4403827483","https://openalex.org/W6967056376"],"related_works":["https://openalex.org/W4379231730","https://openalex.org/W4389858081","https://openalex.org/W2501551404","https://openalex.org/W4298131179","https://openalex.org/W2113201962","https://openalex.org/W4385583601","https://openalex.org/W4395685956","https://openalex.org/W3159516372","https://openalex.org/W4398146871","https://openalex.org/W1522196789"],"abstract_inverted_index":{"Precise":[0],"histopathological":[1,51,197],"image":[2,198],"segmentation":[3,33,62,183],"is":[4],"vital":[5],"for":[6,31,195],"accurate":[7],"diagnosis":[8],"and":[9,27,45,49,70,72,80,85,118,128,142,156,178,185],"treatment":[10],"planning.":[11],"This":[12],"manuscript":[13],"proposes":[14],"a":[15,169,191],"hybrid":[16],"framework,":[17],"PSPNet":[18,21,58,106,189],"EPO-SEB,":[19],"combining":[20],"with":[22,105,146],"an":[23,28],"emperor":[24],"penguin":[25],"optimizer":[26],"attention-enhanced":[29],"module":[30],"improved":[32],"performance.":[34],"The":[35],"model":[36,135],"was":[37],"rigorously":[38],"evaluated":[39],"on":[40,82,126,130,154,158],"two":[41],"prominent":[42],"datasets,":[43,87],"BACH":[44,84,127,155],"Camelyon17,":[46,159],"encompassing":[47],"high-resolution":[48],"whole-slide":[50],"images,":[52],"respectively.":[53,88],"Experimental":[54],"results":[55],"demonstrate":[56],"that":[57],"EPO-SEB":[59,107,190],"outperforms":[60],"conventional":[61],"models,":[63],"achieving":[64],"dice":[65],"coefficients":[66],"(DC)":[67],"of":[68,78,93],"0.9237":[69],"0.9186,":[71],"intersection":[73],"over":[74],"union":[75],"(IoU)":[76],"values":[77],"0.8629":[79],"0.8622":[81],"the":[83,133,181],"Camelyon17":[86],"These":[89],"metrics":[90],"surpass":[91],"those":[92],"competing":[94],"models":[95],"such":[96],"as":[97,150,152],"U-Net,":[98],"V-Net,":[99],"PA-Net,":[100],"FANet18,":[101],"Mask":[102],"R-CNN,":[103],"R2UNet,":[104],"showing":[108],"enhanced":[109,182],"boundary":[110,144,186],"accuracy,":[111],"True":[112],"positive":[113,121],"rates":[114,122,140],"(TPR)":[115],"above":[116],"0.93,":[117],"minimized":[119],"false":[120],"(FPR)":[123],"at":[124],"0.1211":[125],"0.1108":[129],"Camelyon17.":[131],"Furthermore,":[132],"proposed":[134],"maintains":[136],"low":[137,151],"average":[138],"error":[139],"(AER)":[141],"achieves":[143],"precision":[145,184],"Hausdorff":[147],"distances":[148],"(HD)":[149],"12.68":[153],"13.04":[157],"underscoring":[160],"its":[161],"accuracy":[162],"in":[163,172],"delineating":[164],"complex":[165,196],"tissue":[166],"structures.":[167],"Despite":[168],"slight":[170],"increase":[171],"computational":[173],"time":[174],"due":[175],"to":[176],"optimization":[177],"attention":[179],"mechanisms,":[180],"adherence":[187],"make":[188],"highly":[192],"effective":[193],"solution":[194],"analysis.":[199]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-06-15T08:34:33.830935","created_date":"2025-10-10T00:00:00"}
