{"id":"https://openalex.org/W2934973407","doi":"https://doi.org/10.1080/03610918.2019.1592191","title":"A new design of the continual reassessment method","display_name":"A new design of the continual reassessment method","publication_year":2019,"publication_date":"2019-04-03","ids":{"openalex":"https://openalex.org/W2934973407","doi":"https://doi.org/10.1080/03610918.2019.1592191","mag":"2934973407"},"language":"en","primary_location":{"id":"doi:10.1080/03610918.2019.1592191","is_oa":false,"landing_page_url":"https://doi.org/10.1080/03610918.2019.1592191","pdf_url":null,"source":{"id":"https://openalex.org/S153329750","display_name":"Communications in Statistics - Simulation and Computation","issn_l":"0361-0918","issn":["0361-0918","1532-4141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Communications in Statistics - Simulation and Computation","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100457938","display_name":"Weijia Zhang","orcid":"https://orcid.org/0000-0001-8103-5325"},"institutions":[{"id":"https://openalex.org/I46247651","display_name":"University of Manitoba","ror":"https://ror.org/02gfys938","country_code":"CA","type":"education","lineage":["https://openalex.org/I46247651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Weijia Zhang","raw_affiliation_strings":["Department of Statistics, University of Manitoba, Winnipeg, Manitoba, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Statistics, University of Manitoba, Winnipeg, Manitoba, Canada","institution_ids":["https://openalex.org/I46247651"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008086724","display_name":"Xikui Wang","orcid":"https://orcid.org/0000-0002-4157-396X"},"institutions":[{"id":"https://openalex.org/I46247651","display_name":"University of Manitoba","ror":"https://ror.org/02gfys938","country_code":"CA","type":"education","lineage":["https://openalex.org/I46247651"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Xikui Wang","raw_affiliation_strings":["Department of Statistics, University of Manitoba, Winnipeg, Manitoba, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Statistics, University of Manitoba, Winnipeg, Manitoba, Canada","institution_ids":["https://openalex.org/I46247651"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046017507","display_name":"Po Yang","orcid":"https://orcid.org/0000-0002-2976-2047"},"institutions":[{"id":"https://openalex.org/I46247651","display_name":"University of Manitoba","ror":"https://ror.org/02gfys938","country_code":"CA","type":"education","lineage":["https://openalex.org/I46247651"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Po Yang","raw_affiliation_strings":["Department of Statistics, University of Manitoba, Winnipeg, Manitoba, Canada"],"affiliations":[{"raw_affiliation_string":"Department of Statistics, University of Manitoba, Winnipeg, Manitoba, Canada","institution_ids":["https://openalex.org/I46247651"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5008086724"],"corresponding_institution_ids":["https://openalex.org/I46247651"],"apc_list":null,"apc_paid":null,"fwci":0.3961,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.6556499,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"50","issue":"7","first_page":"2015","last_page":"2024"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11798","display_name":"Optimal Experimental Design Methods","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1803","display_name":"Management Science and Operations Research"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11798","display_name":"Optimal Experimental Design Methods","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/1803","display_name":"Management Science and Operations Research"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.9778000116348267,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.904699981212616,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/safeguarding","display_name":"Safeguarding","score":0.8070512413978577},{"id":"https://openalex.org/keywords/benchmark","display_name":"Benchmark (surveying)","score":0.6785187721252441},{"id":"https://openalex.org/keywords/reliability","display_name":"Reliability (semiconductor)","score":0.6528379917144775},{"id":"https://openalex.org/keywords/reliability-engineering","display_name":"Reliability engineering","score":0.584347128868103},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.575823962688446},{"id":"https://openalex.org/keywords/risk-analysis","display_name":"Risk analysis (engineering)","score":0.43271970748901367},{"id":"https://openalex.org/keywords/management-science","display_name":"Management science","score":0.3339994549751282},{"id":"https://openalex.org/keywords/operations-research","display_name":"Operations research","score":0.3326804041862488},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.20477235317230225},{"id":"https://openalex.org/keywords/business","display_name":"Business","score":0.15279728174209595},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.11434996128082275}],"concepts":[{"id":"https://openalex.org/C2776743756","wikidata":"https://www.wikidata.org/wiki/Q5097921","display_name":"Safeguarding","level":2,"score":0.8070512413978577},{"id":"https://openalex.org/C185798385","wikidata":"https://www.wikidata.org/wiki/Q1161707","display_name":"Benchmark (surveying)","level":2,"score":0.6785187721252441},{"id":"https://openalex.org/C43214815","wikidata":"https://www.wikidata.org/wiki/Q7310987","display_name":"Reliability (semiconductor)","level":3,"score":0.6528379917144775},{"id":"https://openalex.org/C200601418","wikidata":"https://www.wikidata.org/wiki/Q2193887","display_name":"Reliability engineering","level":1,"score":0.584347128868103},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.575823962688446},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.43271970748901367},{"id":"https://openalex.org/C539667460","wikidata":"https://www.wikidata.org/wiki/Q2414942","display_name":"Management science","level":1,"score":0.3339994549751282},{"id":"https://openalex.org/C42475967","wikidata":"https://www.wikidata.org/wiki/Q194292","display_name":"Operations research","level":1,"score":0.3326804041862488},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.20477235317230225},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.15279728174209595},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11434996128082275},{"id":"https://openalex.org/C163258240","wikidata":"https://www.wikidata.org/wiki/Q25342","display_name":"Power (physics)","level":2,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1080/03610918.2019.1592191","is_oa":false,"landing_page_url":"https://doi.org/10.1080/03610918.2019.1592191","pdf_url":null,"source":{"id":"https://openalex.org/S153329750","display_name":"Communications in Statistics - Simulation and Computation","issn_l":"0361-0918","issn":["0361-0918","1532-4141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Communications in Statistics - Simulation and Computation","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311952","display_name":"University of Manitoba","ror":"https://ror.org/02gfys938"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W603816075","https://openalex.org/W1973396713","https://openalex.org/W1975592428","https://openalex.org/W1998887752","https://openalex.org/W2000705046","https://openalex.org/W2004133377","https://openalex.org/W2005718639","https://openalex.org/W2006990152","https://openalex.org/W2042990006","https://openalex.org/W2045985885","https://openalex.org/W2054383376","https://openalex.org/W2063214645","https://openalex.org/W2073911899","https://openalex.org/W2075236916","https://openalex.org/W2075757568","https://openalex.org/W2076108528","https://openalex.org/W2084986158","https://openalex.org/W2098980231","https://openalex.org/W2117963308","https://openalex.org/W2118701470","https://openalex.org/W2125102557","https://openalex.org/W2126551611","https://openalex.org/W2141086589","https://openalex.org/W2152155324","https://openalex.org/W2162300921","https://openalex.org/W2168881814","https://openalex.org/W2301770695","https://openalex.org/W2312270541","https://openalex.org/W2324021516","https://openalex.org/W2600484105","https://openalex.org/W2799795409","https://openalex.org/W2952060368"],"related_works":["https://openalex.org/W2033512842","https://openalex.org/W4233600955","https://openalex.org/W4322734194","https://openalex.org/W3116237489","https://openalex.org/W2913665393","https://openalex.org/W2369695847","https://openalex.org/W3005535424","https://openalex.org/W2994319598","https://openalex.org/W2047067935","https://openalex.org/W1607054433"],"abstract_inverted_index":{"We":[0],"propose":[1],"a":[2],"new":[3,35,51],"design":[4,36,52],"of":[5,23],"the":[6,21,34,50,67],"continual":[7],"reassessment":[8],"method":[9],"and":[10,25,55],"systematically":[11],"evaluate":[12],"its":[13],"performance":[14],"on":[15,41],"certain":[16],"operating":[17],"measures":[18],"to":[19,32],"satisfy":[20],"requirements":[22],"collective":[24,73],"individual":[26,62],"ethics.":[27],"Simulation":[28],"results":[29],"are":[30],"derived":[31],"compare":[33],"with":[37],"currently":[38],"available":[39],"designs":[40],"criteria":[42],"BEARS:":[43],"Benchmark,":[44],"Efficiency,":[45],"Accuracy,":[46],"Reliability,":[47],"Safety.":[48],"Overall,":[49],"performs":[53],"well":[54],"safely":[56],"avoids":[57],"toxic":[58],"doses":[59],"(hence":[60,71],"safeguarding":[61],"ethics)":[63],"while":[64],"reliably":[65],"identifying":[66],"maximum":[68],"tolerated":[69],"dose":[70],"protecting":[72],"ethics).":[74]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}