{"id":"https://openalex.org/W2038171185","doi":"https://doi.org/10.1080/03610910903249510","title":"A Comparison of Procedures for Controlling the False Discovery Rate in the Presence of Small Variance Genes: A Simulation Study","display_name":"A Comparison of Procedures for Controlling the False Discovery Rate in the Presence of Small Variance Genes: A Simulation Study","publication_year":2009,"publication_date":"2009-09-29","ids":{"openalex":"https://openalex.org/W2038171185","doi":"https://doi.org/10.1080/03610910903249510","mag":"2038171185"},"language":"en","primary_location":{"id":"doi:10.1080/03610910903249510","is_oa":false,"landing_page_url":"https://doi.org/10.1080/03610910903249510","pdf_url":null,"source":{"id":"https://openalex.org/S153329750","display_name":"Communications in Statistics - Simulation and Computation","issn_l":"0361-0918","issn":["0361-0918","1532-4141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Communications in Statistics - Simulation and Computation","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://hal.science/hal-00524862","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017049788","display_name":"Dan Lin","orcid":"https://orcid.org/0000-0001-8064-5666"},"institutions":[{"id":"https://openalex.org/I878454856","display_name":"Hasselt University","ror":"https://ror.org/04nbhqj75","country_code":"BE","type":"education","lineage":["https://openalex.org/I878454856"]}],"countries":["BE"],"is_corresponding":true,"raw_author_name":"Dan Lin","raw_affiliation_strings":["I-Biostat, Hasselt University , Diepenbeek , Belgium","I-Biostat, Hasselt University, Diepenbeek, Belgium;"],"affiliations":[{"raw_affiliation_string":"I-Biostat, Hasselt University , Diepenbeek , Belgium","institution_ids":["https://openalex.org/I878454856"]},{"raw_affiliation_string":"I-Biostat, Hasselt University, Diepenbeek, Belgium;","institution_ids":["https://openalex.org/I878454856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084282661","display_name":"Ziv Shkedy","orcid":"https://orcid.org/0000-0002-6306-0823"},"institutions":[{"id":"https://openalex.org/I878454856","display_name":"Hasselt University","ror":"https://ror.org/04nbhqj75","country_code":"BE","type":"education","lineage":["https://openalex.org/I878454856"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Ziv Shkedy","raw_affiliation_strings":["I-Biostat, Hasselt University , Diepenbeek , Belgium","I-Biostat, Hasselt University, Diepenbeek, Belgium;"],"affiliations":[{"raw_affiliation_string":"I-Biostat, Hasselt University , Diepenbeek , Belgium","institution_ids":["https://openalex.org/I878454856"]},{"raw_affiliation_string":"I-Biostat, Hasselt University, Diepenbeek, Belgium;","institution_ids":["https://openalex.org/I878454856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066953797","display_name":"Tomasz Burzykowski","orcid":"https://orcid.org/0000-0003-3378-975X"},"institutions":[{"id":"https://openalex.org/I878454856","display_name":"Hasselt University","ror":"https://ror.org/04nbhqj75","country_code":"BE","type":"education","lineage":["https://openalex.org/I878454856"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Tomasz Burzykowski","raw_affiliation_strings":["I-Biostat, Hasselt University , Diepenbeek , Belgium","I-Biostat, Hasselt University, Diepenbeek, Belgium;"],"affiliations":[{"raw_affiliation_string":"I-Biostat, Hasselt University , Diepenbeek , Belgium","institution_ids":["https://openalex.org/I878454856"]},{"raw_affiliation_string":"I-Biostat, Hasselt University, Diepenbeek, Belgium;","institution_ids":["https://openalex.org/I878454856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071375822","display_name":"Willem Talloen","orcid":"https://orcid.org/0000-0003-1762-5755"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Willem Talloen","raw_affiliation_strings":["J&JPRD, Biometrics and Clinical Informatics , Beerse , Belgium"],"affiliations":[{"raw_affiliation_string":"J&JPRD, Biometrics and Clinical Informatics , Beerse , Belgium","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091674188","display_name":"Luc Bijnens","orcid":"https://orcid.org/0000-0002-4126-3152"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luc Bijnens","raw_affiliation_strings":["J&JPRD, Biometrics and Clinical Informatics , Beerse , Belgium"],"affiliations":[{"raw_affiliation_string":"J&JPRD, Biometrics and Clinical Informatics , Beerse , Belgium","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5017049788"],"corresponding_institution_ids":["https://openalex.org/I878454856"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11755341,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"38","issue":"10","first_page":"2111","last_page":"2122"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11798","display_name":"Optimal Experimental Design Methods","score":0.9750999808311462,"subfield":{"id":"https://openalex.org/subfields/1803","display_name":"Management Science and Operations Research"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/false-discovery-rate","display_name":"False discovery rate","score":0.6746253967285156},{"id":"https://openalex.org/keywords/multiple-comparisons-problem","display_name":"Multiple comparisons problem","score":0.5312539935112},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.5113029479980469},{"id":"https://openalex.org/keywords/statistic","display_name":"Statistic","score":0.46518081426620483},{"id":"https://openalex.org/keywords/resampling","display_name":"Resampling","score":0.44905734062194824},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3809959888458252},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.36451399326324463},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.199812114238739},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1966472566127777},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.14837023615837097}],"concepts":[{"id":"https://openalex.org/C193244246","wikidata":"https://www.wikidata.org/wiki/Q5432696","display_name":"False discovery rate","level":3,"score":0.6746253967285156},{"id":"https://openalex.org/C183905921","wikidata":"https://www.wikidata.org/wiki/Q1038757","display_name":"Multiple comparisons problem","level":2,"score":0.5312539935112},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.5113029479980469},{"id":"https://openalex.org/C89128539","wikidata":"https://www.wikidata.org/wiki/Q1949963","display_name":"Statistic","level":2,"score":0.46518081426620483},{"id":"https://openalex.org/C150921843","wikidata":"https://www.wikidata.org/wiki/Q1170431","display_name":"Resampling","level":2,"score":0.44905734062194824},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3809959888458252},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.36451399326324463},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.199812114238739},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1966472566127777},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14837023615837097}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1080/03610910903249510","is_oa":false,"landing_page_url":"https://doi.org/10.1080/03610910903249510","pdf_url":null,"source":{"id":"https://openalex.org/S153329750","display_name":"Communications in Statistics - Simulation and Computation","issn_l":"0361-0918","issn":["0361-0918","1532-4141"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Communications in Statistics - Simulation and Computation","raw_type":"journal-article"},{"id":"pmh:oai:HAL:hal-00524862v1","is_oa":true,"landing_page_url":"https://hal.science/hal-00524862","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Communications in Statistics - Simulation and Computation, 2009, 38 (10), pp.2111-2122. ⟨10.1080/03610910903249510⟩","raw_type":"Journal articles"},{"id":"pmh:oai:documentserver.uhasselt.be:1942/10000","is_oa":false,"landing_page_url":"http://hdl.handle.net/1942/10000","pdf_url":null,"source":{"id":"https://openalex.org/S4306401926","display_name":"Document Server@UHasselt (UHasselt)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I878454856","host_organization_name":"Hasselt University","host_organization_lineage":["https://openalex.org/I878454856"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:tara.tcd.ie:2262/46787","is_oa":false,"landing_page_url":"http://hdl.handle.net/2262/46787","pdf_url":null,"source":{"id":"https://openalex.org/S4306400387","display_name":"Trinity's Access to Research Output (TARA) (Trinity College Dublin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205274468","host_organization_name":"Trinity College Dublin","host_organization_lineage":["https://openalex.org/I205274468"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""}],"best_oa_location":{"id":"pmh:oai:HAL:hal-00524862v1","is_oa":true,"landing_page_url":"https://hal.science/hal-00524862","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Communications in Statistics - Simulation and Computation, 2009, 38 (10), pp.2111-2122. ⟨10.1080/03610910903249510⟩","raw_type":"Journal articles"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W103269551","https://openalex.org/W1549870369","https://openalex.org/W2032892178","https://openalex.org/W2060449515","https://openalex.org/W2063978378","https://openalex.org/W2074089196","https://openalex.org/W2091841926","https://openalex.org/W2105381419","https://openalex.org/W2110065044","https://openalex.org/W2120865735","https://openalex.org/W2135046866","https://openalex.org/W2137807839","https://openalex.org/W2145261680","https://openalex.org/W2157795344","https://openalex.org/W2168611083","https://openalex.org/W2497297917","https://openalex.org/W4294107304","https://openalex.org/W4299437137"],"related_works":["https://openalex.org/W4293336298","https://openalex.org/W2467227750","https://openalex.org/W2093104131","https://openalex.org/W2178204436","https://openalex.org/W4300887971","https://openalex.org/W2143079975","https://openalex.org/W2333750400","https://openalex.org/W1986765826","https://openalex.org/W2113381189","https://openalex.org/W2058846847"],"abstract_inverted_index":{"The":[0,94],"Significance":[1,25,162,278],"Analysis":[2],"of":[3,27,37,41,51,79,83,90,96,110,119,164,169,189,210,226,280,285,305,344,347],"Microarrays":[4],"(SAM;":[5],"Tusher":[6,10],"et":[7,122,238],"al.,":[8],"2001":[9,23],",":[11,14,16,18,20,54,126,128,130,132,134,136,138,142,145,147,149,151,153,155,157,192,242,244,246,248,250,252,254,258,261,263,265,267,269,271,273,308],"V.":[12],"G.":[13,21],"Tibshirani":[15],"R.":[17],"Chu":[19],"(":[22,159,180,275,296],").":[24,161,277],"analysis":[26,163,279],"microarrys":[28],"applied":[29],"to":[30,100,114,215,318,337],"the":[31,38,68,75,80,84,88,91,97,101,107,115,198,205,208,211,216,220,224,232,324,328,339,342,345,348],"ionizing":[32],"radiation":[33],"response":[34],".":[35,175,291],"Proceedings":[36],"National":[39],"Academy":[40],"Sciences":[42],"98":[43],":":[44],"5116":[45],"\u2013":[46,184,300],"5121":[47],".[Crossref],":[48,186,302],"[PubMed],":[49,187,303],"[Web":[50,188,304],"Science":[52,190,306],"\u00ae]":[53,191,307],"[Google":[55,193,309],"Scholar])":[56,194],"method":[57],"is":[58,87],"widely":[59],"used":[60],"in":[61,74,223,236,311,327],"analyzing":[62],"gene":[63],"expression":[64],"data":[65],"while":[66],"controlling":[67],"FDR":[69,212,346],"by":[70,231],"using":[71],"resampling-based":[72],"procedure":[73,86,218],"microarray":[76,165,281],"setting.":[77],"One":[78],"main":[81],"components":[82],"SAM":[85,217],"adjustment":[89],"test":[92,102,111,331],"statistic.":[93],"introduction":[95],"fudge":[98,199,221,325],"factor":[99,200,222,326],"statistic":[103],"aims":[104],"at":[105],"deflating":[106],"large":[108],"value":[109],"statistics":[112,332],"due":[113],"small":[116,227],"standard":[117],"error":[118],"gene-expression.":[120],"Lin":[121,125,237,241],"al.":[123,239],"(2008":[124,240],"D.":[127,243],"Shkedy":[129,245],"Z.":[131,247],"Burzykowski":[133,249],"T.":[135,150,154,251,266,270],"G\u00f6hlmann":[137,253],"H.":[139,141,255,257],"W.":[140,256],"De":[143,259],"Bondt":[144,260],"A.":[146,262],"Perera":[148,264],"Geerts":[152,268],"Bijnens":[156,272],"L.":[158,274],"2008":[160,276],"(SAM)":[166,282],"for":[167,283,322],"comparisons":[168,284],"several":[170,286,320],"treatments":[171,287],"with":[172,288],"one":[173,289],"control":[174,209,290,343],"Biometric":[176,292],"Journal,":[177,293],"MCP":[178,294],"50":[179,295],"5":[181,297],"):":[182,298],"801":[183,299],"823":[185,301],"pointed":[195],"out":[196],"that":[197],"does":[201],"not":[202],"effectively":[203],"improve":[204],"power":[206,340],"and":[207,333,341],"as":[213],"compared":[214],"without":[219],"presence":[225],"variance":[228],"genes.":[229],"Motivated":[230],"simulation":[233,335],"results":[234],"presented":[235],"Scholar]),":[310],"this":[312],"article,":[313],"we":[314],"extend":[315],"our":[316],"study":[317],"compare":[319],"methods":[321],"choosing":[323],"modified":[329],"t-type":[330],"use":[334],"studies":[336],"investigate":[338],"considered":[349],"methods.":[350]},"counts_by_year":[],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2016-06-24T00:00:00"}