{"id":"https://openalex.org/W2069668754","doi":"https://doi.org/10.1080/00207720412331303660","title":"Searching oligo sets of human chromosome 12 using evolutionary strategies","display_name":"Searching oligo sets of human chromosome 12 using evolutionary strategies","publication_year":2004,"publication_date":"2004-10-20","ids":{"openalex":"https://openalex.org/W2069668754","doi":"https://doi.org/10.1080/00207720412331303660","mag":"2069668754"},"language":"en","primary_location":{"id":"doi:10.1080/00207720412331303660","is_oa":false,"landing_page_url":"https://doi.org/10.1080/00207720412331303660","pdf_url":null,"source":{"id":"https://openalex.org/S129640837","display_name":"International Journal of Systems Science","issn_l":"0020-7721","issn":["0020-7721","1464-5319"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Systems Science","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066476052","display_name":"Yeonsoo Joe","orcid":"https://orcid.org/0009-0007-1939-853X"},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":true,"raw_author_name":"Yen-Yen Joe","raw_affiliation_strings":["Department of Electrical and Computer Engineering , National University of Singapore , 4 Engineering Drive 3, Singapore 117576"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering , National University of Singapore , 4 Engineering Drive 3, Singapore 117576","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085887197","display_name":"Arthur Tay","orcid":"https://orcid.org/0000-0002-3197-2369"},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Arthur Tay *","raw_affiliation_strings":["Department of Electrical and Computer Engineering , National University of Singapore , 4 Engineering Drive 3, Singapore 117576"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering , National University of Singapore , 4 Engineering Drive 3, Singapore 117576","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112415925","display_name":"Zhaoyang Dong","orcid":null},"institutions":[{"id":"https://openalex.org/I165143802","display_name":"University of Queensland","ror":"https://ror.org/00rqy9422","country_code":"AU","type":"education","lineage":["https://openalex.org/I165143802"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Zhao-Yang Dong","raw_affiliation_strings":["School of Information Technology and Electrical Engineering, University of Queensland , St. Lucia, QLD 4072, Australia"],"affiliations":[{"raw_affiliation_string":"School of Information Technology and Electrical Engineering, University of Queensland , St. Lucia, QLD 4072, Australia","institution_ids":["https://openalex.org/I165143802"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018084310","display_name":"Huck\u2010Hui Ng","orcid":"https://orcid.org/0000-0001-6352-8417"},"institutions":[{"id":"https://openalex.org/I66068411","display_name":"Genome Institute of Singapore","ror":"https://ror.org/05k8wg936","country_code":"SG","type":"facility","lineage":["https://openalex.org/I115228651","https://openalex.org/I2801752549","https://openalex.org/I66068411"]},{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Huck-Hui Ng","raw_affiliation_strings":["Department of Biological Sciences , National University of Singapore , 14 Science Drive 4, Singapore 117543; Genome Institute of Singapore , 1 Science Park Road, The Capricorn, #05-01, Singapore 117528","Genome Institute of Singapore , 1 Science Park Road, The Capricorn, #05-01, Singapore 117528","Department of Biological Sciences , National University of Singapore , 14 Science Drive 4, Singapore 117543"],"affiliations":[{"raw_affiliation_string":"Department of Biological Sciences , National University of Singapore , 14 Science Drive 4, Singapore 117543; Genome Institute of Singapore , 1 Science Park Road, The Capricorn, #05-01, Singapore 117528","institution_ids":["https://openalex.org/I66068411"]},{"raw_affiliation_string":"Genome Institute of Singapore , 1 Science Park Road, The Capricorn, #05-01, Singapore 117528","institution_ids":["https://openalex.org/I66068411"]},{"raw_affiliation_string":"Department of Biological Sciences , National University of Singapore , 14 Science Drive 4, Singapore 117543","institution_ids":["https://openalex.org/I165932596"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101817120","display_name":"Huan Xu","orcid":"https://orcid.org/0000-0002-5712-0308"},"institutions":[{"id":"https://openalex.org/I165932596","display_name":"National University of Singapore","ror":"https://ror.org/01tgyzw49","country_code":"SG","type":"education","lineage":["https://openalex.org/I165932596"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Huan Xu","raw_affiliation_strings":["Department of Electrical and Computer Engineering , National University of Singapore , 4 Engineering Drive 3, Singapore 117576"],"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering , National University of Singapore , 4 Engineering Drive 3, Singapore 117576","institution_ids":["https://openalex.org/I165932596"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5066476052"],"corresponding_institution_ids":["https://openalex.org/I165932596"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.10067651,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"35","issue":"13-14","first_page":"787","last_page":"800"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.995199978351593,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.9922999739646912,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nucleic-acid","display_name":"Nucleic acid","score":0.5748257637023926},{"id":"https://openalex.org/keywords/delegate","display_name":"Delegate","score":0.5286536812782288},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5198776721954346},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.4614642262458801},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.442172110080719},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4277694821357727},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.4108712375164032},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.40661507844924927},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3506345748901367},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3357839584350586},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.29304951429367065}],"concepts":[{"id":"https://openalex.org/C24107716","wikidata":"https://www.wikidata.org/wiki/Q123619","display_name":"Nucleic acid","level":2,"score":0.5748257637023926},{"id":"https://openalex.org/C143273055","wikidata":"https://www.wikidata.org/wiki/Q2382794","display_name":"Delegate","level":2,"score":0.5286536812782288},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5198776721954346},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.4614642262458801},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.442172110080719},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4277694821357727},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4108712375164032},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40661507844924927},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3506345748901367},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3357839584350586},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29304951429367065},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1080/00207720412331303660","is_oa":false,"landing_page_url":"https://doi.org/10.1080/00207720412331303660","pdf_url":null,"source":{"id":"https://openalex.org/S129640837","display_name":"International Journal of Systems Science","issn_l":"0020-7721","issn":["0020-7721","1464-5319"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547"],"host_organization_lineage_names":["Taylor & Francis"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Systems Science","raw_type":"journal-article"},{"id":"pmh:oai:scholarbank.nus.edu.sg:10635/51032","is_oa":false,"landing_page_url":"http://scholarbank.nus.edu.sg/handle/10635/51032","pdf_url":null,"source":{"id":"https://openalex.org/S7407052290","display_name":"National University of Singapore","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scopus","raw_type":"Article"},{"id":"pmh:oai:espace.library.uq.edu.au:UQ:72385","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":{"id":"https://openalex.org/S4306402388","display_name":"Queensland's institutional digital repository (The University of Queensland)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I165143802","host_organization_name":"The University of Queensland","host_organization_lineage":["https://openalex.org/I165143802"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Responsible consumption and production","score":0.550000011920929,"id":"https://metadata.un.org/sdg/12"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1498178627","https://openalex.org/W1592614241","https://openalex.org/W1970663985","https://openalex.org/W1972936421","https://openalex.org/W2008907996","https://openalex.org/W2009095852","https://openalex.org/W2029441111","https://openalex.org/W2052729310","https://openalex.org/W2055043387","https://openalex.org/W2073850430","https://openalex.org/W2116390865","https://openalex.org/W2166187656","https://openalex.org/W2547213816","https://openalex.org/W4255988860"],"related_works":["https://openalex.org/W2031284701","https://openalex.org/W3141203889","https://openalex.org/W1969486489","https://openalex.org/W2156039046","https://openalex.org/W2418771911","https://openalex.org/W3140622617","https://openalex.org/W2994187804","https://openalex.org/W2960441665","https://openalex.org/W2070558560","https://openalex.org/W17472890"],"abstract_inverted_index":{"DNA":[0,63,94],"Microarray":[1],"is":[2,44,121],"a":[3,11,76,90,98,111],"powerful":[4],"tool":[5],"to":[6,33,46,59,70,110],"measure":[7],"the":[8,107],"level":[9],"of":[10,14,27,86,92,128],"mixed":[12],"population":[13],"nucleic":[15,35],"acids":[16,36],"at":[17],"one":[18],"time,":[19],"which":[20],"has":[21],"great":[22],"impact":[23],"in":[24],"many":[25],"aspects":[26],"life":[28],"sciences":[29],"research.":[30],"In":[31],"order":[32],"distinguish":[34],"with":[37,50,72],"very":[38],"similar":[39],"composition":[40],"by":[41,125],"hybridization,":[42],"it":[43],"necessary":[45],"design":[47],"microarray":[48],"probes":[49,57,60,68,88],"high":[51],"specificities":[52],"and":[53,79],"sensitivities.":[54],"Highly":[55],"specific":[56],"correspond":[58,69],"having":[61,80],"unique":[62],"sequences;":[64],"whereas":[65],"highly":[66],"sensitive":[67],"those":[71],"melting":[73],"temperature":[74],"within":[75],"desired":[77],"range":[78],"no":[81],"secondary":[82],"structure.":[83],"The":[84,118],"selection":[85],"these":[87],"from":[89],"set":[91],"functional":[93],"sequences":[95],"(exons)":[96],"constitutes":[97],"computationally":[99],"expensive":[100],"discrete":[101],"non-linear":[102],"search":[103,108],"problem.":[104],"We":[105],"delegate":[106],"task":[109],"simple":[112],"yet":[113],"effective":[114],"Evolution":[115],"Strategy":[116],"algorithm.":[117],"computational":[119],"efficiency":[120],"also":[122],"greatly":[123],"improved":[124],"making":[126],"use":[127],"an":[129],"available":[130],"bioinformatics":[131],"tool.":[132]},"counts_by_year":[],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}