{"id":"https://openalex.org/W3080345913","doi":"https://doi.org/10.1073/pnas.2013768117","title":"Reply to Semelidou and Skoulakis: \u201cShort-term\u201d habituation has multiple distinct mechanisms","display_name":"Reply to Semelidou and Skoulakis: \u201cShort-term\u201d habituation has multiple distinct mechanisms","publication_year":2020,"publication_date":"2020-08-25","ids":{"openalex":"https://openalex.org/W3080345913","doi":"https://doi.org/10.1073/pnas.2013768117","mag":"3080345913","pmid":"https://pubmed.ncbi.nlm.nih.gov/32843562"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.2013768117","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.2013768117","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"type":"letter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7456100","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014424245","display_name":"Yang Shen","orcid":"https://orcid.org/0000-0002-6344-9951"},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yang Shen","raw_affiliation_strings":["Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724;"],"affiliations":[{"raw_affiliation_string":"Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724;","institution_ids":["https://openalex.org/I2750212522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101707744","display_name":"Sanjoy Dasgupta","orcid":"https://orcid.org/0000-0002-5960-5157"},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California, San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sanjoy Dasgupta","raw_affiliation_strings":["Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA 92093"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science and Engineering, University of California San Diego, La Jolla, CA 92093","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060581759","display_name":"Saket Navlakha","orcid":"https://orcid.org/0000-0002-5505-9718"},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Saket Navlakha","raw_affiliation_strings":["Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724;"],"affiliations":[{"raw_affiliation_string":"Simons Center for Quantitative Biology, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724;","institution_ids":["https://openalex.org/I2750212522"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5060581759"],"corresponding_institution_ids":["https://openalex.org/I2750212522"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.07504052,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"117","issue":"34","first_page":"20373","last_page":"20374"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10971","display_name":"Olfactory and Sensory Function Studies","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10423","display_name":"Neurobiology and Insect Physiology Research","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10487","display_name":"Plant and animal studies","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/habituation","display_name":"Habituation","score":0.9897882342338562},{"id":"https://openalex.org/keywords/mushroom-bodies","display_name":"Mushroom bodies","score":0.5375914573669434},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5319481492042542},{"id":"https://openalex.org/keywords/term","display_name":"Term (time)","score":0.4476828873157501},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.43559786677360535},{"id":"https://openalex.org/keywords/cognitive-psychology","display_name":"Cognitive psychology","score":0.33150723576545715},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.32779690623283386},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.18634814023971558},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.07051149010658264}],"concepts":[{"id":"https://openalex.org/C50610925","wikidata":"https://www.wikidata.org/wiki/Q1136816","display_name":"Habituation","level":2,"score":0.9897882342338562},{"id":"https://openalex.org/C2776038537","wikidata":"https://www.wikidata.org/wiki/Q1362803","display_name":"Mushroom bodies","level":4,"score":0.5375914573669434},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5319481492042542},{"id":"https://openalex.org/C61797465","wikidata":"https://www.wikidata.org/wiki/Q1188986","display_name":"Term (time)","level":2,"score":0.4476828873157501},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.43559786677360535},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.33150723576545715},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32779690623283386},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.18634814023971558},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07051149010658264},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C2780104201","wikidata":"https://www.wikidata.org/wiki/Q130888","display_name":"Drosophila melanogaster","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006185","descriptor_name":"Habituation, Psychophysiologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006185","descriptor_name":"Habituation, Psychophysiologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006185","descriptor_name":"Habituation, Psychophysiologic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009812","descriptor_name":"Odorants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009812","descriptor_name":"Odorants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009812","descriptor_name":"Odorants","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1073/pnas.2013768117","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.2013768117","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:32843562","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32843562","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":null},{"id":"pmh:oai:repository.cshl.edu:39760","is_oa":false,"landing_page_url":"https://repository.cshl.edu/id/eprint/39760/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402288","display_name":"Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Paper"},{"id":"pmh:oai:pubmedcentral.nih.gov:7456100","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7456100","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:7456100","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7456100","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W2001654698","https://openalex.org/W2005811042","https://openalex.org/W2078556860","https://openalex.org/W2087349770","https://openalex.org/W2726159424","https://openalex.org/W2767902147","https://openalex.org/W2905989589","https://openalex.org/W2953571514","https://openalex.org/W3026672761","https://openalex.org/W3080508047"],"related_works":["https://openalex.org/W1974089501","https://openalex.org/W2611753819","https://openalex.org/W2088977183","https://openalex.org/W2132921858","https://openalex.org/W2052143611","https://openalex.org/W2018610517","https://openalex.org/W2147292125","https://openalex.org/W78964092","https://openalex.org/W2072371975","https://openalex.org/W2155662890"],"abstract_inverted_index":{"The":[0],"Letter":[1,27],"by":[2,89],"Semelidou":[3],"and":[4,28],"Skoulakis":[5],"(1)":[6],"questions":[7],"the":[8,23,43,48,55,63,80,86],"congruence":[9],"of":[10,18,42,57],"our":[11,52],"model":[12,53],"(2)":[13],"with":[14],"current":[15],"experimental":[16],"evidence":[17],"olfactory":[19],"habituation.":[20],"We":[21,68],"thank":[22],"authors":[24,49],"for":[25],"their":[26],"would":[29],"like":[30],"to":[31],"make":[32],"three":[33],"points":[34],"in":[35],"response.\n\n#####":[36],"1)":[37],"Re:":[38],"\u201cand":[39],"is":[40],"independent":[41],"mushroom":[44,64],"bodies,":[45],"unlike":[46],"what":[47],"propose.\u201d\n\nTo":[50],"clarify,":[51],"studied":[54],"effect":[56],"antennae":[58],"lobe":[59],"(AL)":[60],"habituation":[61,74],"on":[62],"body":[65],"(MB)":[66],"downstream.":[67],"did":[69],"not":[70],"propose":[71],"that":[72],"30-min":[73],"itself":[75],"occurs":[76],"in,":[77],"or":[78],"requires,":[79],"MB.":[81],"Indeed,":[82],"we":[83],"directly":[84],"followed":[85],"mechanism":[87],"proposed":[88],"\u2026":[90],"\n\n[\u21b5][1]1To":[91],"whom":[92],"correspondence":[93],"may":[94],"be":[95],"addressed.":[96],"Email:":[97],"navlakha{at}cshl.edu.\n\n":[98],"[1]:":[99],"#xref-corresp-1-1":[100]},"counts_by_year":[],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}