{"id":"https://openalex.org/W2067337097","doi":"https://doi.org/10.1073/pnas.0605534104","title":"A consensus view of protein dynamics","display_name":"A consensus view of protein dynamics","publication_year":2007,"publication_date":"2007-01-10","ids":{"openalex":"https://openalex.org/W2067337097","doi":"https://doi.org/10.1073/pnas.0605534104","mag":"2067337097","pmid":"https://pubmed.ncbi.nlm.nih.gov/17215349"},"language":"en","primary_location":{"id":"doi:10.1073/pnas.0605534104","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0605534104","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1783393","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5023487324","display_name":"Manuel Rueda","orcid":"https://orcid.org/0000-0001-9280-058X"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":true,"raw_author_name":"Manuel Rueda","raw_affiliation_strings":["*Molecular Modelling and Bioinformatics Unit and","Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Molecular Modelling and Bioinformatics Unit and","institution_ids":[]},{"raw_affiliation_string":"Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019450935","display_name":"Carles Ferrer\u2010Costa","orcid":"https://orcid.org/0000-0002-3779-8808"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Carles Ferrer-Costa","raw_affiliation_strings":["*Molecular Modelling and Bioinformatics Unit and","Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Molecular Modelling and Bioinformatics Unit and","institution_ids":[]},{"raw_affiliation_string":"Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040619925","display_name":"Tim Meyer","orcid":"https://orcid.org/0000-0002-0521-6711"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Tim Meyer","raw_affiliation_strings":["*Molecular Modelling and Bioinformatics Unit and","Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","Departament de Bioqu\u00edmica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Avgda Diagonal 645, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Molecular Modelling and Bioinformatics Unit and","institution_ids":[]},{"raw_affiliation_string":"Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]},{"raw_affiliation_string":"Departament de Bioqu\u00edmica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Avgda Diagonal 645, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063704705","display_name":"Alberto P\u00e9rez","orcid":"https://orcid.org/0000-0002-5054-5338"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Alberto P\u00e9rez","raw_affiliation_strings":["*Molecular Modelling and Bioinformatics Unit and","Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Molecular Modelling and Bioinformatics Unit and","institution_ids":[]},{"raw_affiliation_string":"Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101651509","display_name":"Jordi Camps","orcid":"https://orcid.org/0000-0001-8763-9947"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I4210122345","display_name":"Institute for Research in Biomedicine","ror":"https://ror.org/01z1gye03","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210122345","https://openalex.org/I4210132884","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Jordi Camps","raw_affiliation_strings":["Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","Structural Biology Node, Institut de Recerca Biom\u00e8dica, Parc Cient\u00edfic de Barcelona, Josep Samitier 1-5, 08028 Barcelona, Spain;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]},{"raw_affiliation_string":"Structural Biology Node, Institut de Recerca Biom\u00e8dica, Parc Cient\u00edfic de Barcelona, Josep Samitier 1-5, 08028 Barcelona, Spain;","institution_ids":["https://openalex.org/I4210122345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088134705","display_name":"Josep Lluis Gelp\u00ed","orcid":"https://orcid.org/0000-0002-0566-7723"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I4210122345","display_name":"Institute for Research in Biomedicine","ror":"https://ror.org/01z1gye03","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210122345","https://openalex.org/I4210132884","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Josep Lluis Gelp\u00ed","raw_affiliation_strings":["*Molecular Modelling and Bioinformatics Unit and","Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","Departament de Bioqu\u00edmica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Avgda Diagonal 645, 08028 Barcelona, Spain","Structural Biology Node, Institut de Recerca Biom\u00e8dica, Parc Cient\u00edfic de Barcelona, Josep Samitier 1-5, 08028 Barcelona, Spain;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Molecular Modelling and Bioinformatics Unit and","institution_ids":[]},{"raw_affiliation_string":"Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]},{"raw_affiliation_string":"Departament de Bioqu\u00edmica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Avgda Diagonal 645, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]},{"raw_affiliation_string":"Structural Biology Node, Institut de Recerca Biom\u00e8dica, Parc Cient\u00edfic de Barcelona, Josep Samitier 1-5, 08028 Barcelona, Spain;","institution_ids":["https://openalex.org/I4210122345"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006399866","display_name":"Modesto Orozco","orcid":"https://orcid.org/0000-0002-8608-3278"},"institutions":[{"id":"https://openalex.org/I2799803557","display_name":"Barcelona Supercomputing Center","ror":"https://ror.org/05sd8tv96","country_code":"ES","type":"facility","lineage":["https://openalex.org/I2799803557","https://openalex.org/I9617848"]},{"id":"https://openalex.org/I4210122345","display_name":"Institute for Research in Biomedicine","ror":"https://ror.org/01z1gye03","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210122345","https://openalex.org/I4210132884","https://openalex.org/I4387153040"]},{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]},{"id":"https://openalex.org/I9617848","display_name":"Universitat Polit\u00e8cnica de Catalunya","ror":"https://ror.org/03mb6wj31","country_code":"ES","type":"education","lineage":["https://openalex.org/I9617848"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Modesto Orozco","raw_affiliation_strings":["*Molecular Modelling and Bioinformatics Unit and","Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","Departament de Bioqu\u00edmica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Avgda Diagonal 645, 08028 Barcelona, Spain","Structural Biology Node, Institut de Recerca Biom\u00e8dica, Parc Cient\u00edfic de Barcelona, Josep Samitier 1-5, 08028 Barcelona, Spain;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"*Molecular Modelling and Bioinformatics Unit and","institution_ids":[]},{"raw_affiliation_string":"Computational Biology Program, Barcelona Supercomputing Center, Jordi Girona 31, Edifici Nexus II, 08028 Barcelona, Spain; and","institution_ids":["https://openalex.org/I9617848","https://openalex.org/I2799803557"]},{"raw_affiliation_string":"Departament de Bioqu\u00edmica i Biologia Molecular, Facultat de Biologia, Universitat de Barcelona, Avgda Diagonal 645, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]},{"raw_affiliation_string":"Structural Biology Node, Institut de Recerca Biom\u00e8dica, Parc Cient\u00edfic de Barcelona, Josep Samitier 1-5, 08028 Barcelona, Spain;","institution_ids":["https://openalex.org/I4210122345"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5023487324"],"corresponding_institution_ids":["https://openalex.org/I2799803557","https://openalex.org/I9617848"],"apc_list":null,"apc_paid":null,"fwci":9.1495,"has_fulltext":false,"cited_by_count":227,"citation_normalized_percentile":{"value":0.9869771,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"104","issue":"3","first_page":"796","last_page":"801"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11177","display_name":"Spectroscopy and Quantum Chemical Studies","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12748","display_name":"Molecular spectroscopy and chirality","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-dynamics","display_name":"Molecular dynamics","score":0.6715915203094482},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6627009510993958},{"id":"https://openalex.org/keywords/terabyte","display_name":"Terabyte","score":0.5899936556816101},{"id":"https://openalex.org/keywords/protein-dynamics","display_name":"Protein dynamics","score":0.5741040110588074},{"id":"https://openalex.org/keywords/dynamics","display_name":"Dynamics (music)","score":0.5065077543258667},{"id":"https://openalex.org/keywords/aqueous-solution","display_name":"Aqueous solution","score":0.49437832832336426},{"id":"https://openalex.org/keywords/computational-science","display_name":"Computational science","score":0.4937337338924408},{"id":"https://openalex.org/keywords/opls","display_name":"OPLS","score":0.4217129945755005},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.4013289213180542},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.343191921710968},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.335695743560791},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.321649968624115},{"id":"https://openalex.org/keywords/water-model","display_name":"Water model","score":0.320654034614563},{"id":"https://openalex.org/keywords/computational-chemistry","display_name":"Computational chemistry","score":0.23774266242980957},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.19835472106933594},{"id":"https://openalex.org/keywords/physical-chemistry","display_name":"Physical chemistry","score":0.12461432814598083},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.09324046969413757}],"concepts":[{"id":"https://openalex.org/C59593255","wikidata":"https://www.wikidata.org/wiki/Q901663","display_name":"Molecular dynamics","level":2,"score":0.6715915203094482},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6627009510993958},{"id":"https://openalex.org/C199683683","wikidata":"https://www.wikidata.org/wiki/Q8799","display_name":"Terabyte","level":2,"score":0.5899936556816101},{"id":"https://openalex.org/C2775981520","wikidata":"https://www.wikidata.org/wiki/Q17156992","display_name":"Protein dynamics","level":3,"score":0.5741040110588074},{"id":"https://openalex.org/C145912823","wikidata":"https://www.wikidata.org/wiki/Q113558","display_name":"Dynamics (music)","level":2,"score":0.5065077543258667},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.49437832832336426},{"id":"https://openalex.org/C459310","wikidata":"https://www.wikidata.org/wiki/Q117801","display_name":"Computational science","level":1,"score":0.4937337338924408},{"id":"https://openalex.org/C38660458","wikidata":"https://www.wikidata.org/wiki/Q7072834","display_name":"OPLS","level":4,"score":0.4217129945755005},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.4013289213180542},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.343191921710968},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.335695743560791},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.321649968624115},{"id":"https://openalex.org/C119049451","wikidata":"https://www.wikidata.org/wiki/Q3318070","display_name":"Water model","level":3,"score":0.320654034614563},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.23774266242980957},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.19835472106933594},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.12461432814598083},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09324046969413757},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D011506","descriptor_name":"Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017510","descriptor_name":"Protein Folding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019906","descriptor_name":"Nuclear Magnetic Resonance, Biomolecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019906","descriptor_name":"Nuclear Magnetic Resonance, Biomolecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019906","descriptor_name":"Nuclear Magnetic Resonance, Biomolecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019906","descriptor_name":"Nuclear Magnetic Resonance, Biomolecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1073/pnas.0605534104","is_oa":false,"landing_page_url":"https://doi.org/10.1073/pnas.0605534104","pdf_url":null,"source":{"id":"https://openalex.org/S125754415","display_name":"Proceedings of the National Academy of Sciences","issn_l":"0027-8424","issn":["0027-8424","1091-6490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320052","host_organization_name":"National Academy of Sciences","host_organization_lineage":["https://openalex.org/P4310320052"],"host_organization_lineage_names":["National Academy of Sciences"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences","raw_type":"journal-article"},{"id":"pmid:17215349","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17215349","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Proceedings of the National Academy of Sciences of the United States of America","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:1783393","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1783393","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1783393","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1783393","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Proc Natl Acad Sci U S A","raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":58,"referenced_works":["https://openalex.org/W1491824558","https://openalex.org/W1969505913","https://openalex.org/W1974225312","https://openalex.org/W1976499671","https://openalex.org/W1977482735","https://openalex.org/W1979046104","https://openalex.org/W1980705414","https://openalex.org/W1981021420","https://openalex.org/W1986191025","https://openalex.org/W1989939737","https://openalex.org/W1998643862","https://openalex.org/W2003329164","https://openalex.org/W2005477948","https://openalex.org/W2008708467","https://openalex.org/W2011691446","https://openalex.org/W2012907468","https://openalex.org/W2017727500","https://openalex.org/W2018046436","https://openalex.org/W2027408247","https://openalex.org/W2031616354","https://openalex.org/W2040503203","https://openalex.org/W2041902442","https://openalex.org/W2042243687","https://openalex.org/W2050956052","https://openalex.org/W2050956531","https://openalex.org/W2051101876","https://openalex.org/W2051381895","https://openalex.org/W2052500616","https://openalex.org/W2054881399","https://openalex.org/W2058206198","https://openalex.org/W2061776631","https://openalex.org/W2063750781","https://openalex.org/W2066196541","https://openalex.org/W2067174909","https://openalex.org/W2076961986","https://openalex.org/W2077042715","https://openalex.org/W2079199763","https://openalex.org/W2081431207","https://openalex.org/W2085277871","https://openalex.org/W2087596773","https://openalex.org/W2093221728","https://openalex.org/W2103815459","https://openalex.org/W2106140689","https://openalex.org/W2118619377","https://openalex.org/W2122199548","https://openalex.org/W2125725297","https://openalex.org/W2132589721","https://openalex.org/W2148077714","https://openalex.org/W2150981663","https://openalex.org/W2157165549","https://openalex.org/W2159010139","https://openalex.org/W2160975112","https://openalex.org/W2161151688","https://openalex.org/W2168606024","https://openalex.org/W2171268876","https://openalex.org/W2171807422","https://openalex.org/W4234347480","https://openalex.org/W6756564037"],"related_works":["https://openalex.org/W4221044347","https://openalex.org/W2033901909","https://openalex.org/W2170876386","https://openalex.org/W2056226223","https://openalex.org/W3118625909","https://openalex.org/W3175401845","https://openalex.org/W3105414059","https://openalex.org/W1990520598","https://openalex.org/W2611887774","https://openalex.org/W2181561360"],"abstract_inverted_index":{"The":[0],"dynamics":[1,21,69],"of":[2,17,43,47,51,58,67],"proteins":[3],"in":[4,70],"aqueous":[5,71],"solution":[6],"has":[7],"been":[8],"investigated":[9],"through":[10],"a":[11,64],"massive":[12,45],"approach":[13],"based":[14],"on":[15],"\"state":[16],"the":[18,29,44],"art\"":[19],"molecular":[20],"simulations":[22],"performed":[23],"for":[24],"all":[25],"protein":[26,68],"metafolds":[27],"using":[28,54],"four":[30],"most":[31],"popular":[32],"force":[33],"fields":[34],"(OPLS,":[35],"CHARMM,":[36],"AMBER,":[37],"and":[38],"GROMOS).":[39],"A":[40],"detailed":[41],"analysis":[42],"database":[46],"trajectories":[48],"(>1.5":[49],"terabytes":[50],"data":[52],"obtained":[53],"approximately":[55],"50":[56],"years":[57],"CPU)":[59],"allowed":[60],"us":[61],"to":[62],"obtain":[63],"robust-consensus":[65],"picture":[66],"solution.":[72]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":11},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":15},{"year":2016,"cited_by_count":12},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":16},{"year":2012,"cited_by_count":22}],"updated_date":"2026-06-07T08:38:57.713557","created_date":"2025-10-10T00:00:00"}