{"id":"https://openalex.org/W7131096556","doi":"https://doi.org/10.1038/s43588-026-00957-3","title":"Self-optimized spectral distance for low-light high-throughput Raman hyperspectral imaging","display_name":"Self-optimized spectral distance for low-light high-throughput Raman hyperspectral imaging","publication_year":2026,"publication_date":"2026-02-23","ids":{"openalex":"https://openalex.org/W7131096556","doi":"https://doi.org/10.1038/s43588-026-00957-3","pmid":"https://pubmed.ncbi.nlm.nih.gov/41731036"},"language":"en","primary_location":{"id":"doi:10.1038/s43588-026-00957-3","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s43588-026-00957-3","pdf_url":null,"source":{"id":"https://openalex.org/S4210228084","display_name":"Nature Computational Science","issn_l":"2662-8457","issn":["2662-8457"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Computational Science","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101508336","display_name":"Yuehua Chen","orcid":"https://orcid.org/0000-0002-4646-4017"},"institutions":[{"id":"https://openalex.org/I4210121405","display_name":"Centre for Artificial Intelligence and Robotics","ror":"https://ror.org/01xnbq218","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I4210121405","https://openalex.org/I4210150591"]},{"id":"https://openalex.org/I4210144102","display_name":"Wuhu Hit Robot Technology Research Institute","ror":"https://ror.org/049w4dp92","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210144102"]}],"countries":["CN","IN"],"is_corresponding":false,"raw_author_name":"Yurong Chen","raw_affiliation_strings":["National Engineering Research Center of Robot Visual Perception and Control Technology, Changsha, China","School of Artificial Intelligence and Robotics, Hunan University, Changsha, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Engineering Research Center of Robot Visual Perception and Control Technology, Changsha, China","institution_ids":["https://openalex.org/I4210144102"]},{"raw_affiliation_string":"School of Artificial Intelligence and Robotics, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I4210121405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126605364","display_name":"Shen Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shen Wang","raw_affiliation_strings":["College of Chemistry and Chemical Engineering, Hunan University, Changsha, China","College of Environmental Science and Engineering, Hunan University, Changsha, China","Molecular Science and Biomedicine Laboratory (MBL), Hunan University, Changsha, China","State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Chemistry and Chemical Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"College of Environmental Science and Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"Molecular Science and Biomedicine Laboratory (MBL), Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126639237","display_name":"Yaonan Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]},{"id":"https://openalex.org/I4210144102","display_name":"Wuhu Hit Robot Technology Research Institute","ror":"https://ror.org/049w4dp92","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210144102"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yaonan Wang","raw_affiliation_strings":["National Engineering Research Center of Robot Visual Perception and Control Technology, Changsha, China. yaonan@hnu.edu.cn","School of Artificial Intelligence and Robotics, Hunan University, Changsha, China. yaonan@hnu.edu.cn"],"raw_orcid":"https://orcid.org/0000-0002-0519-6458","affiliations":[{"raw_affiliation_string":"National Engineering Research Center of Robot Visual Perception and Control Technology, Changsha, China. yaonan@hnu.edu.cn","institution_ids":["https://openalex.org/I4210144102"]},{"raw_affiliation_string":"School of Artificial Intelligence and Robotics, Hunan University, Changsha, China. yaonan@hnu.edu.cn","institution_ids":["https://openalex.org/I16609230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065039433","display_name":"Jianxu Mao","orcid":"https://orcid.org/0000-0003-2267-5415"},"institutions":[{"id":"https://openalex.org/I4210121405","display_name":"Centre for Artificial Intelligence and Robotics","ror":"https://ror.org/01xnbq218","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I4210121405","https://openalex.org/I4210150591"]},{"id":"https://openalex.org/I4210144102","display_name":"Wuhu Hit Robot Technology Research Institute","ror":"https://ror.org/049w4dp92","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210144102"]}],"countries":["CN","IN"],"is_corresponding":false,"raw_author_name":"Jianxu Mao","raw_affiliation_strings":["National Engineering Research Center of Robot Visual Perception and Control Technology, Changsha, China","School of Artificial Intelligence and Robotics, Hunan University, Changsha, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Engineering Research Center of Robot Visual Perception and Control Technology, Changsha, China","institution_ids":["https://openalex.org/I4210144102"]},{"raw_affiliation_string":"School of Artificial Intelligence and Robotics, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I4210121405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126586907","display_name":"Lizhu Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210121405","display_name":"Centre for Artificial Intelligence and Robotics","ror":"https://ror.org/01xnbq218","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I4210121405","https://openalex.org/I4210150591"]},{"id":"https://openalex.org/I4210144102","display_name":"Wuhu Hit Robot Technology Research Institute","ror":"https://ror.org/049w4dp92","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210144102"]}],"countries":["CN","IN"],"is_corresponding":false,"raw_author_name":"Lizhu Liu","raw_affiliation_strings":["National Engineering Research Center of Robot Visual Perception and Control Technology, Changsha, China","School of Artificial Intelligence and Robotics, Hunan University, Changsha, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Engineering Research Center of Robot Visual Perception and Control Technology, Changsha, China","institution_ids":["https://openalex.org/I4210144102"]},{"raw_affiliation_string":"School of Artificial Intelligence and Robotics, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I4210121405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019297044","display_name":"Xiaoxu Cao","orcid":"https://orcid.org/0000-0002-9562-1234"},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoxu Cao","raw_affiliation_strings":["College of Chemistry and Chemical Engineering, Hunan University, Changsha, China","College of Environmental Science and Engineering, Hunan University, Changsha, China","Molecular Science and Biomedicine Laboratory (MBL), Hunan University, Changsha, China","State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Chemistry and Chemical Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"College of Environmental Science and Engineering, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"Molecular Science and Biomedicine Laboratory (MBL), Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China","institution_ids":["https://openalex.org/I16609230"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126643094","display_name":"Zhuo Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuo Chen","raw_affiliation_strings":["College of Chemistry and Chemical Engineering, Hunan University, Changsha, China. zhuochen@hnu.edu.cn","College of Environmental Science and Engineering, Hunan University, Changsha, China. zhuochen@hnu.edu.cn","Molecular Science and Biomedicine Laboratory (MBL), Hunan University, Changsha, China. zhuochen@hnu.edu.cn","State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China. zhuochen@hnu.edu.cn"],"raw_orcid":"https://orcid.org/0000-0002-9943-2262","affiliations":[{"raw_affiliation_string":"College of Chemistry and Chemical Engineering, Hunan University, Changsha, China. zhuochen@hnu.edu.cn","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"College of Environmental Science and Engineering, Hunan University, Changsha, China. zhuochen@hnu.edu.cn","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"Molecular Science and Biomedicine Laboratory (MBL), Hunan University, Changsha, China. zhuochen@hnu.edu.cn","institution_ids":["https://openalex.org/I16609230"]},{"raw_affiliation_string":"State Key Laboratory of Chemo and Biosensing, Hunan University, Changsha, China. zhuochen@hnu.edu.cn","institution_ids":["https://openalex.org/I16609230"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5126652012","display_name":"Hui Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I16609230","display_name":"Hunan University","ror":"https://ror.org/05htk5m33","country_code":"CN","type":"education","lineage":["https://openalex.org/I16609230"]},{"id":"https://openalex.org/I4210144102","display_name":"Wuhu Hit Robot Technology Research Institute","ror":"https://ror.org/049w4dp92","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210144102"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Hui Zhang","raw_affiliation_strings":["National Engineering Research Center of Robot Visual Perception and Control Technology, Changsha, China. zhanghui1983@hnu.edu.cn","School of Artificial Intelligence and Robotics, Hunan University, Changsha, China. zhanghui1983@hnu.edu.cn"],"raw_orcid":"https://orcid.org/0000-0002-1803-3148","affiliations":[{"raw_affiliation_string":"National Engineering Research Center of Robot Visual Perception and Control Technology, Changsha, China. zhanghui1983@hnu.edu.cn","institution_ids":["https://openalex.org/I4210144102"]},{"raw_affiliation_string":"School of Artificial Intelligence and Robotics, Hunan University, Changsha, China. zhanghui1983@hnu.edu.cn","institution_ids":["https://openalex.org/I16609230"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5126639237","https://openalex.org/A5126652012"],"corresponding_institution_ids":["https://openalex.org/I16609230","https://openalex.org/I4210144102"],"apc_list":{"value":9750,"currency":"EUR","value_usd":11690},"apc_paid":null,"fwci":8.6595,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.9560924,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"6","issue":"6","first_page":"603","last_page":"616"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11324","display_name":"Spectroscopy Techniques in Biomedical and Chemical Research","score":0.9771000146865845,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.008299999870359898,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10131","display_name":"Gold and Silver Nanoparticles Synthesis and Applications","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2504","display_name":"Electronic, Optical and Magnetic Materials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hyperspectral-imaging","display_name":"Hyperspectral imaging","score":0.8974000215530396},{"id":"https://openalex.org/keywords/raman-spectroscopy","display_name":"Raman spectroscopy","score":0.8238999843597412},{"id":"https://openalex.org/keywords/raman-scattering","display_name":"Raman scattering","score":0.7001000046730042},{"id":"https://openalex.org/keywords/chemical-imaging","display_name":"Chemical imaging","score":0.6031000018119812},{"id":"https://openalex.org/keywords/spectral-imaging","display_name":"Spectral imaging","score":0.5023000240325928},{"id":"https://openalex.org/keywords/signal","display_name":"SIGNAL (programming language)","score":0.4634999930858612},{"id":"https://openalex.org/keywords/limiting","display_name":"Limiting","score":0.367900013923645},{"id":"https://openalex.org/keywords/coherent-anti-stokes-raman-spectroscopy","display_name":"Coherent anti-Stokes Raman spectroscopy","score":0.329800009727478}],"concepts":[{"id":"https://openalex.org/C159078339","wikidata":"https://www.wikidata.org/wiki/Q959005","display_name":"Hyperspectral imaging","level":2,"score":0.8974000215530396},{"id":"https://openalex.org/C40003534","wikidata":"https://www.wikidata.org/wiki/Q862228","display_name":"Raman spectroscopy","level":2,"score":0.8238999843597412},{"id":"https://openalex.org/C169573571","wikidata":"https://www.wikidata.org/wiki/Q466824","display_name":"Raman scattering","level":3,"score":0.7001000046730042},{"id":"https://openalex.org/C65597285","wikidata":"https://www.wikidata.org/wiki/Q5090469","display_name":"Chemical imaging","level":3,"score":0.6031000018119812},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.5162000060081482},{"id":"https://openalex.org/C3232514","wikidata":"https://www.wikidata.org/wiki/Q7575196","display_name":"Spectral imaging","level":2,"score":0.5023000240325928},{"id":"https://openalex.org/C2779843651","wikidata":"https://www.wikidata.org/wiki/Q7390335","display_name":"SIGNAL (programming language)","level":2,"score":0.4634999930858612},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.42500001192092896},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3711000084877014},{"id":"https://openalex.org/C188198153","wikidata":"https://www.wikidata.org/wiki/Q1613840","display_name":"Limiting","level":2,"score":0.367900013923645},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33959999680519104},{"id":"https://openalex.org/C205309187","wikidata":"https://www.wikidata.org/wiki/Q903528","display_name":"Coherent anti-Stokes Raman spectroscopy","level":4,"score":0.329800009727478},{"id":"https://openalex.org/C176641082","wikidata":"https://www.wikidata.org/wiki/Q2446767","display_name":"Spectral signature","level":2,"score":0.320499986410141},{"id":"https://openalex.org/C163985040","wikidata":"https://www.wikidata.org/wiki/Q1172399","display_name":"Data acquisition","level":2,"score":0.3197000026702881},{"id":"https://openalex.org/C158479148","wikidata":"https://www.wikidata.org/wiki/Q609991","display_name":"Imaging spectroscopy","level":3,"score":0.3165999948978424},{"id":"https://openalex.org/C78660771","wikidata":"https://www.wikidata.org/wiki/Q5508206","display_name":"Full spectral imaging","level":3,"score":0.3052000105381012},{"id":"https://openalex.org/C83581075","wikidata":"https://www.wikidata.org/wiki/Q1361503","display_name":"Excitation","level":2,"score":0.3019999861717224},{"id":"https://openalex.org/C2993001476","wikidata":"https://www.wikidata.org/wiki/Q13553575","display_name":"Excitation wavelength","level":3,"score":0.3001999855041504},{"id":"https://openalex.org/C205372480","wikidata":"https://www.wikidata.org/wiki/Q210521","display_name":"Image resolution","level":2,"score":0.2992999851703644},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2833000123500824},{"id":"https://openalex.org/C163258240","wikidata":"https://www.wikidata.org/wiki/Q25342","display_name":"Power (physics)","level":2,"score":0.2827000021934509},{"id":"https://openalex.org/C32891209","wikidata":"https://www.wikidata.org/wiki/Q483666","display_name":"Spectroscopy","level":2,"score":0.2750000059604645},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.2587999999523163}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1038/s43588-026-00957-3","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s43588-026-00957-3","pdf_url":null,"source":{"id":"https://openalex.org/S4210228084","display_name":"Nature Computational Science","issn_l":"2662-8457","issn":["2662-8457"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Computational Science","raw_type":"journal-article"},{"id":"pmid:41731036","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41731036","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature computational science","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1963973293","https://openalex.org/W2045901799","https://openalex.org/W2057428057","https://openalex.org/W2072443063","https://openalex.org/W2074880343","https://openalex.org/W2090511991","https://openalex.org/W2104460891","https://openalex.org/W2114486983","https://openalex.org/W2115318086","https://openalex.org/W2127062304","https://openalex.org/W2133665775","https://openalex.org/W2136035751","https://openalex.org/W2157321686","https://openalex.org/W2168187747","https://openalex.org/W2194775991","https://openalex.org/W2591646821","https://openalex.org/W2604425999","https://openalex.org/W2752782242","https://openalex.org/W2799842393","https://openalex.org/W2884585870","https://openalex.org/W2963571608","https://openalex.org/W2964013315","https://openalex.org/W2970018556","https://openalex.org/W2982827138","https://openalex.org/W2989757802","https://openalex.org/W3034902810","https://openalex.org/W3195625084","https://openalex.org/W3212784736","https://openalex.org/W4292363360","https://openalex.org/W4311675337","https://openalex.org/W4313546446","https://openalex.org/W4327858945","https://openalex.org/W4362673666","https://openalex.org/W4387969737","https://openalex.org/W4388623498","https://openalex.org/W4389574259","https://openalex.org/W4391215304","https://openalex.org/W4394565732","https://openalex.org/W4396925879","https://openalex.org/W4396948308","https://openalex.org/W7106581262"],"related_works":[],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-06-25T06:16:34.145877","created_date":"2026-02-24T00:00:00"}