{"id":"https://openalex.org/W4392201057","doi":"https://doi.org/10.1038/s43588-024-00594-8","title":"Characterizing emerging companies in computational drug development","display_name":"Characterizing emerging companies in computational drug development","publication_year":2024,"publication_date":"2024-02-26","ids":{"openalex":"https://openalex.org/W4392201057","doi":"https://doi.org/10.1038/s43588-024-00594-8","pmid":"https://pubmed.ncbi.nlm.nih.gov/38413778"},"language":"en","primary_location":{"id":"doi:10.1038/s43588-024-00594-8","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s43588-024-00594-8","pdf_url":null,"source":{"id":"https://openalex.org/S4210228084","display_name":"Nature Computational Science","issn_l":"2662-8457","issn":["2662-8457"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Computational Science","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5094013608","display_name":"Chloe Markey","orcid":"https://orcid.org/0009-0006-4176-3145"},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Chloe Markey","raw_affiliation_strings":["Department of Biomedical Engineering, Duke University, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050861360","display_name":"Samuel Croset","orcid":"https://orcid.org/0000-0002-9591-0060"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Samuel Croset","raw_affiliation_strings":["Bellevue Asset Management, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bellevue Asset Management, Zurich, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108314675","display_name":"Olivia Woolley","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Olivia Ruth Woolley","raw_affiliation_strings":["Bellevue Asset Management, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bellevue Asset Management, Zurich, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113128488","display_name":"Can Martin Buldun","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Can Martin Buldun","raw_affiliation_strings":["Bellevue Asset Management, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bellevue Asset Management, Zurich, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101471696","display_name":"Christian Koch","orcid":"https://orcid.org/0009-0003-4741-4171"},"institutions":[{"id":"https://openalex.org/I174135032","display_name":"Bellevue College","ror":"https://ror.org/05gr4yv49","country_code":"US","type":"education","lineage":["https://openalex.org/I174135032"]},{"id":"https://openalex.org/I58064216","display_name":"Bellevue University","ror":"https://ror.org/00b7ckn36","country_code":"US","type":"education","lineage":["https://openalex.org/I58064216"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christian Koch","raw_affiliation_strings":["Bellevue Asset Management, Zurich, Switzerland. cko@bellevue.ch","Bellevue Asset Management, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0009-0003-4741-4171","affiliations":[{"raw_affiliation_string":"Bellevue Asset Management, Zurich, Switzerland. cko@bellevue.ch","institution_ids":["https://openalex.org/I58064216","https://openalex.org/I174135032"]},{"raw_affiliation_string":"Bellevue Asset Management, Zurich, Switzerland","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5094013609","display_name":"Daniel Koller","orcid":"https://orcid.org/0009-0002-3388-3295"},"institutions":[{"id":"https://openalex.org/I174135032","display_name":"Bellevue College","ror":"https://ror.org/05gr4yv49","country_code":"US","type":"education","lineage":["https://openalex.org/I174135032"]},{"id":"https://openalex.org/I58064216","display_name":"Bellevue University","ror":"https://ror.org/00b7ckn36","country_code":"US","type":"education","lineage":["https://openalex.org/I58064216"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Koller","raw_affiliation_strings":["Bellevue Asset Management, Zurich, Switzerland. dk@bellevue.ch","Bellevue Asset Management, Zurich, Switzerland"],"raw_orcid":"https://orcid.org/0009-0002-3388-3295","affiliations":[{"raw_affiliation_string":"Bellevue Asset Management, Zurich, Switzerland. dk@bellevue.ch","institution_ids":["https://openalex.org/I58064216","https://openalex.org/I174135032"]},{"raw_affiliation_string":"Bellevue Asset Management, Zurich, Switzerland","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020392456","display_name":"Daniel Reker","orcid":"https://orcid.org/0000-0003-4789-7380"},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Reker","raw_affiliation_strings":["Department of Biomedical Engineering, Duke University, Durham, NC, USA. daniel.reker@duke.edu","Department of Biomedical Engineering, Duke University, Durham, NC, USA"],"raw_orcid":"https://orcid.org/0000-0003-4789-7380","affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Duke University, Durham, NC, USA. daniel.reker@duke.edu","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Biomedical Engineering, Duke University, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5094013608"],"corresponding_institution_ids":["https://openalex.org/I170897317"],"apc_list":{"value":9750,"currency":"EUR","value_usd":11690},"apc_paid":null,"fwci":3.8027,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.9373932,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"4","issue":"2","first_page":"96","last_page":"103"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9864000082015991,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9864000082015991,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.9544000029563904,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11407","display_name":"Innovative Microfluidic and Catalytic Techniques Innovation","score":0.9369999766349792,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-development","display_name":"Drug development","score":0.5939080715179443},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.4813445508480072},{"id":"https://openalex.org/keywords/business","display_name":"Business","score":0.4286733865737915},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3832717537879944},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.19794529676437378},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.1269146203994751}],"concepts":[{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.5939080715179443},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4813445508480072},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.4286733865737915},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3832717537879944},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.19794529676437378},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.1269146203994751}],"mesh":[{"descriptor_ui":"D000076722","descriptor_name":"Drug Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076722","descriptor_name":"Drug Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076722","descriptor_name":"Drug Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076722","descriptor_name":"Drug Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076722","descriptor_name":"Drug Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076722","descriptor_name":"Drug Development","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004345","descriptor_name":"Drug Industry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004345","descriptor_name":"Drug Industry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004345","descriptor_name":"Drug Industry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004345","descriptor_name":"Drug Industry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004345","descriptor_name":"Drug Industry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004345","descriptor_name":"Drug Industry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1038/s43588-024-00594-8","is_oa":false,"landing_page_url":"https://doi.org/10.1038/s43588-024-00594-8","pdf_url":null,"source":{"id":"https://openalex.org/S4210228084","display_name":"Nature Computational Science","issn_l":"2662-8457","issn":["2662-8457"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Computational Science","raw_type":"journal-article"},{"id":"pmid:38413778","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38413778","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature computational science","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3180533204","display_name":null,"funder_award_id":"R35GM151255","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6825827435","display_name":null,"funder_award_id":"NIH T32 GM133352-4","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1979847955","https://openalex.org/W2104334710","https://openalex.org/W2169055592","https://openalex.org/W2180898434","https://openalex.org/W2806547269","https://openalex.org/W2918813360","https://openalex.org/W2972497960","https://openalex.org/W3014780529","https://openalex.org/W3023882637","https://openalex.org/W3031603244","https://openalex.org/W3043005121","https://openalex.org/W3111015203","https://openalex.org/W3113150977","https://openalex.org/W3123782511","https://openalex.org/W3139275483","https://openalex.org/W4247084342","https://openalex.org/W4296526508","https://openalex.org/W4309198190","https://openalex.org/W4315927809","https://openalex.org/W4318958140","https://openalex.org/W4319944262","https://openalex.org/W4366823237","https://openalex.org/W6966959916"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W1585256759"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":4}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}