{"id":"https://openalex.org/W7162878388","doi":"https://doi.org/10.1038/s41746-026-02821-0","title":"Sensor wide association studies in digital medicine","display_name":"Sensor wide association studies in digital medicine","publication_year":2026,"publication_date":"2026-05-30","ids":{"openalex":"https://openalex.org/W7162878388","doi":"https://doi.org/10.1038/s41746-026-02821-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/42218250"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-026-02821-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02821-0","pdf_url":"https://www.nature.com/articles/s41746-026-02821-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-026-02821-0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088871320","display_name":"Nico Steckhan","orcid":"https://orcid.org/0000-0003-0245-2046"},"institutions":[{"id":"https://openalex.org/I143288331","display_name":"Hasso Plattner Institute","ror":"https://ror.org/058rn5r42","country_code":"DE","type":"facility","lineage":["https://openalex.org/I143288331","https://openalex.org/I176453806"]},{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]},{"id":"https://openalex.org/I96424156","display_name":"Federal Institute for Occupational Safety and Health","ror":"https://ror.org/01aa1sn70","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I96424156"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Nico Steckhan","raw_affiliation_strings":["Department for Prevention and Care of Diabetes, Department of Medicine III, Faculty of Medicine Carl Gustav Carus, Technische Universit\u00e4t Dresden, Dresden, Germany. nico.steckhan@hpi.de","Digital Health - Connected Healthcare, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany. nico.steckhan@hpi.de","Federal Institute for Occupational Safety and Health, Dresden, Germany. nico.steckhan@hpi.de"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department for Prevention and Care of Diabetes, Department of Medicine III, Faculty of Medicine Carl Gustav Carus, Technische Universit\u00e4t Dresden, Dresden, Germany. nico.steckhan@hpi.de","institution_ids":["https://openalex.org/I4210162051"]},{"raw_affiliation_string":"Digital Health - Connected Healthcare, Hasso Plattner Institute, University of Potsdam, Potsdam, Germany. nico.steckhan@hpi.de","institution_ids":["https://openalex.org/I143288331"]},{"raw_affiliation_string":"Federal Institute for Occupational Safety and Health, Dresden, Germany. nico.steckhan@hpi.de","institution_ids":["https://openalex.org/I96424156"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034258709","display_name":"Felix Broghammer","orcid":null},"institutions":[{"id":"https://openalex.org/I4210162051","display_name":"University Hospital Carl Gustav Carus","ror":"https://ror.org/04za5zm41","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210162051"]},{"id":"https://openalex.org/I78650965","display_name":"Technische Universit\u00e4t Dresden","ror":"https://ror.org/042aqky30","country_code":"DE","type":"education","lineage":["https://openalex.org/I78650965"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Felix Broghammer","raw_affiliation_strings":["Department for Prevention and Care of Diabetes, Department of Medicine III, Faculty of Medicine Carl Gustav Carus, Technische Universit\u00e4t Dresden, Dresden, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department for Prevention and Care of Diabetes, Department of Medicine III, Faculty of Medicine Carl Gustav Carus, Technische Universit\u00e4t Dresden, Dresden, Germany","institution_ids":["https://openalex.org/I4210162051","https://openalex.org/I78650965"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034401148","display_name":"Dylan Powell","orcid":"https://orcid.org/0000-0003-1233-5468"},"institutions":[{"id":"https://openalex.org/I12093191","display_name":"University of Stirling","ror":"https://ror.org/045wgfr59","country_code":"GB","type":"education","lineage":["https://openalex.org/I12093191"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dylan Powell","raw_affiliation_strings":["Faculty of Health Sciences & Sport, University of Stirling, Stirling, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences & Sport, University of Stirling, Stirling, UK","institution_ids":["https://openalex.org/I12093191"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5088871320"],"corresponding_institution_ids":["https://openalex.org/I143288331","https://openalex.org/I4210162051","https://openalex.org/I96424156"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":{"value":3590,"currency":"USD","value_usd":3590},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.66385822,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.3930000066757202,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11519","display_name":"Digital Mental Health Interventions","score":0.3930000066757202,"subfield":{"id":"https://openalex.org/subfields/3202","display_name":"Applied Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11446","display_name":"Mobile Health and mHealth Applications","score":0.09019999951124191,"subfield":{"id":"https://openalex.org/subfields/3600","display_name":"General Health Professions"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14393","display_name":"Health, Environment, Cognitive Aging","score":0.07530000060796738,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/association","display_name":"Association (psychology)","score":0.6406999826431274},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.5454999804496765},{"id":"https://openalex.org/keywords/perspective","display_name":"Perspective (graphical)","score":0.5253000259399414},{"id":"https://openalex.org/keywords/digital-health","display_name":"Digital health","score":0.49869999289512634},{"id":"https://openalex.org/keywords/precision-medicine","display_name":"Precision medicine","score":0.3921999931335449},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.3465999960899353},{"id":"https://openalex.org/keywords/personalized-medicine","display_name":"Personalized medicine","score":0.329800009727478},{"id":"https://openalex.org/keywords/longitudinal-data","display_name":"Longitudinal data","score":0.31369999051094055}],"concepts":[{"id":"https://openalex.org/C142853389","wikidata":"https://www.wikidata.org/wiki/Q744778","display_name":"Association (psychology)","level":2,"score":0.6406999826431274},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.5454999804496765},{"id":"https://openalex.org/C12713177","wikidata":"https://www.wikidata.org/wiki/Q1900281","display_name":"Perspective (graphical)","level":2,"score":0.5253000259399414},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5002999901771545},{"id":"https://openalex.org/C2780433410","wikidata":"https://www.wikidata.org/wiki/Q5276090","display_name":"Digital health","level":3,"score":0.49869999289512634},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.40720000863075256},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40470001101493835},{"id":"https://openalex.org/C163763905","wikidata":"https://www.wikidata.org/wiki/Q17075943","display_name":"Precision medicine","level":2,"score":0.3921999931335449},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.36809998750686646},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.3465999960899353},{"id":"https://openalex.org/C32220436","wikidata":"https://www.wikidata.org/wiki/Q2072214","display_name":"Personalized medicine","level":2,"score":0.329800009727478},{"id":"https://openalex.org/C3020672099","wikidata":"https://www.wikidata.org/wiki/Q857354","display_name":"Longitudinal data","level":2,"score":0.31369999051094055},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.30720001459121704},{"id":"https://openalex.org/C193524817","wikidata":"https://www.wikidata.org/wiki/Q386780","display_name":"Association rule learning","level":2,"score":0.2793999910354614},{"id":"https://openalex.org/C2778864079","wikidata":"https://www.wikidata.org/wiki/Q173285","display_name":"Digital data","level":3,"score":0.2791000008583069},{"id":"https://openalex.org/C2780966255","wikidata":"https://www.wikidata.org/wiki/Q5474306","display_name":"Foundation (evidence)","level":2,"score":0.27900001406669617},{"id":"https://openalex.org/C148483581","wikidata":"https://www.wikidata.org/wiki/Q446488","display_name":"Feature selection","level":2,"score":0.2727999985218048},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.26019999384880066},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.25999999046325684},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.25850000977516174},{"id":"https://openalex.org/C168167062","wikidata":"https://www.wikidata.org/wiki/Q1117970","display_name":"Component (thermodynamics)","level":2,"score":0.2563999891281128},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.2549000084400177},{"id":"https://openalex.org/C126082660","wikidata":"https://www.wikidata.org/wiki/Q4252370","display_name":"Digital transformation","level":2,"score":0.25209999084472656}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-026-02821-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02821-0","pdf_url":"https://www.nature.com/articles/s41746-026-02821-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:42218250","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42218250","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:b3d3d089a0c94986afa32906400c2df1","is_oa":true,"landing_page_url":"https://doaj.org/article/b3d3d089a0c94986afa32906400c2df1","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 9, Iss 1 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13222335","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13222335/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-026-02821-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02821-0","pdf_url":"https://www.nature.com/articles/s41746-026-02821-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6563891172409058,"display_name":"Good health and well-being"}],"awards":[],"funders":[{"id":"https://openalex.org/F5720118025","display_name":"Deutsches Zentrum f\u00fcr Diabetesforschung","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7162878388.pdf","grobid_xml":"https://content.openalex.org/works/W7162878388.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1986705681","https://openalex.org/W2009187570","https://openalex.org/W2064675550","https://openalex.org/W2082246284","https://openalex.org/W2118502261","https://openalex.org/W2149860264","https://openalex.org/W2575460524","https://openalex.org/W3023519397","https://openalex.org/W3025060722","https://openalex.org/W3042750741","https://openalex.org/W3095708005","https://openalex.org/W4221073130","https://openalex.org/W4231057675","https://openalex.org/W4286560842","https://openalex.org/W4294168018","https://openalex.org/W4304080209","https://openalex.org/W4318669539","https://openalex.org/W4385236202","https://openalex.org/W4391747349","https://openalex.org/W4391997539","https://openalex.org/W4392138070","https://openalex.org/W4399731507","https://openalex.org/W4399793782","https://openalex.org/W4405567015","https://openalex.org/W4411282918"],"related_works":[],"abstract_inverted_index":{"Assoziation":[0],"studies":[1],"revolutionized":[2],"genomics":[3],"by":[4],"rigorously":[5],"screening":[6],"large":[7],"feature":[8,54],"sets":[9],"against":[10,45],"health":[11],"outcomes.":[12],"Digital":[13],"medicine":[14],"now":[15],"produces":[16],"similarly":[17],"high-dimensional,":[18],"longitudinal":[19,57],"sensor":[20],"data":[21],"from":[22],"wearables,":[23],"smartphones,":[24],"and":[25,59,72,85],"connected":[26],"environments.":[27],"We":[28],"propose":[29],"Sensor-Wide":[30],"Association":[31],"Studies":[32],"(SWAS):":[33],"structured,":[34],"feature-wide,":[35],"hypothesis-generating":[36],"scans":[37],"of":[38,42,62],"a":[39,79],"pre-specified":[40],"library":[41],"sensor-derived":[43],"features":[44],"one":[46],"or":[47],"more":[48],"pre-defined":[49],"clinical":[50],"phenotypes,":[51],"with":[52],"transparent":[53],"documentation,":[55],"appropriate":[56],"modeling,":[58],"principled":[60],"control":[61],"multiplicity.":[63],"This":[64],"perspective":[65],"outlines":[66],"minimal":[67],"standards,":[68],"common":[69],"failure":[70],"modes,":[71],"ethical":[73],"considerations":[74],"to":[75],"help":[76],"SWAS":[77],"become":[78],"reproducible":[80],"foundation":[81],"for":[82],"digital":[83],"epidemiology":[84],"personalized":[86],"medicine.":[87]},"counts_by_year":[],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2026-05-31T00:00:00"}