{"id":"https://openalex.org/W7155640318","doi":"https://doi.org/10.1038/s41746-026-02670-x","title":"Integrating multimodal clinical data with a large model for prostate cancer diagnosis","display_name":"Integrating multimodal clinical data with a large model for prostate cancer diagnosis","publication_year":2026,"publication_date":"2026-04-25","ids":{"openalex":"https://openalex.org/W7155640318","doi":"https://doi.org/10.1038/s41746-026-02670-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/42034911"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-026-02670-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02670-x","pdf_url":"https://www.nature.com/articles/s41746-026-02670-x_reference.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-026-02670-x_reference.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066717596","display_name":"C Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chengbang Wang","raw_affiliation_strings":["Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210097066","https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134594225","display_name":"Yuan Tian","orcid":null},"institutions":[{"id":"https://openalex.org/I4210100255","display_name":"Beijing Academy of Artificial Intelligence","ror":"https://ror.org/016a74861","country_code":"CN","type":"other","lineage":["https://openalex.org/I4210100255"]},{"id":"https://openalex.org/I4391012619","display_name":"Shanghai Artificial Intelligence Laboratory","ror":"https://ror.org/03wkvpx79","country_code":null,"type":"facility","lineage":["https://openalex.org/I4391012619"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuan Tian","raw_affiliation_strings":["Shanghai Artificial Intelligence Laboratory, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Shanghai Artificial Intelligence Laboratory, Shanghai, China","institution_ids":["https://openalex.org/I4210100255","https://openalex.org/I4391012619"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134596432","display_name":"Shaojie Yin","orcid":null},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shaojie Yin","raw_affiliation_strings":["Institute of Image Communication and Network Engineering, Shanghai Jiao Tong University, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Image Communication and Network Engineering, Shanghai Jiao Tong University, Shanghai, China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100430876","display_name":"Xi Zhang","orcid":"https://orcid.org/0000-0003-3415-5345"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuhong Zhang","raw_affiliation_strings":["Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210097066","https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134611354","display_name":"Xuedong Wei","orcid":null},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]},{"id":"https://openalex.org/I4210153519","display_name":"First Affiliated Hospital of Soochow University","ror":"https://ror.org/051jg5p78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153519"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xuedong Wei","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, China","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210153519"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053863666","display_name":"Lingfeng Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210092870","display_name":"Jiaxing University","ror":"https://ror.org/00j2a7k55","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210092870"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lingfeng Wu","raw_affiliation_strings":["Department of Urology, The Affiliated Hospital of Jiaxing University, Jiaxing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Affiliated Hospital of Jiaxing University, Jiaxing, China","institution_ids":["https://openalex.org/I4210092870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052505059","display_name":"Zhengdong Zhou","orcid":null},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]},{"id":"https://openalex.org/I4210119554","display_name":"Yancheng First People's Hospital","ror":"https://ror.org/02rbkz523","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210119554"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhengdong Zhou","raw_affiliation_strings":["Department of Urology, Yancheng First Hospital, Affiliated Hospital of Nanjing University Medical School, The First people's Hospital of Yancheng, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Yancheng First Hospital, Affiliated Hospital of Nanjing University Medical School, The First people's Hospital of Yancheng, Jiangsu, China","institution_ids":["https://openalex.org/I4210119554","https://openalex.org/I199305430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076241726","display_name":"Guijian Pang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210126060","display_name":"First Affiliated Hospital of GuangXi Medical University","ror":"https://ror.org/030sc3x20","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210126060"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guijian Pang","raw_affiliation_strings":["Department of Urology, The First People's Hospital of Yulin (the Sixth Affiliated Hospital of Guangxi Medical University), Yulin, Guangxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First People's Hospital of Yulin (the Sixth Affiliated Hospital of Guangxi Medical University), Yulin, Guangxi, China","institution_ids":["https://openalex.org/I4210126060"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100633632","display_name":"Yue Wang","orcid":"https://orcid.org/0000-0003-0098-5359"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Wang","raw_affiliation_strings":["Department of Urology, Changhai Hospital, Second Military Medical University (Naval Medical University), Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Changhai Hospital, Second Military Medical University (Naval Medical University), Shanghai, China","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210115928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134577543","display_name":"Wangjian Wu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210092870","display_name":"Jiaxing University","ror":"https://ror.org/00j2a7k55","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210092870"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wangjian Wu","raw_affiliation_strings":["Department of Urology, The Affiliated Hospital of Jiaxing University, Jiaxing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Affiliated Hospital of Jiaxing University, Jiaxing, China","institution_ids":["https://openalex.org/I4210092870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134593342","display_name":"Shukai Zhao","orcid":null},"institutions":[{"id":"https://openalex.org/I3923682","display_name":"Soochow University","ror":"https://ror.org/05t8y2r12","country_code":"CN","type":"education","lineage":["https://openalex.org/I3923682"]},{"id":"https://openalex.org/I4210153519","display_name":"First Affiliated Hospital of Soochow University","ror":"https://ror.org/051jg5p78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153519"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shukai Zhao","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital of Soochow University, Suzhou, China","institution_ids":["https://openalex.org/I3923682","https://openalex.org/I4210153519"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100389372","display_name":"Ziwei Wang","orcid":"https://orcid.org/0000-0002-3237-1522"},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ziwei Wang","raw_affiliation_strings":["Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China","institution_ids":["https://openalex.org/I4210097066","https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080931518","display_name":"Jiangnan Xu","orcid":"https://orcid.org/0000-0002-8957-948X"},"institutions":[{"id":"https://openalex.org/I199305430","display_name":"Nantong University","ror":"https://ror.org/02afcvw97","country_code":"CN","type":"education","lineage":["https://openalex.org/I199305430"]},{"id":"https://openalex.org/I4210119554","display_name":"Yancheng First People's Hospital","ror":"https://ror.org/02rbkz523","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210119554"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiangnan Xu","raw_affiliation_strings":["Department of Urology, Yancheng First Hospital, Affiliated Hospital of Nanjing University Medical School, The First people's Hospital of Yancheng, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Yancheng First Hospital, Affiliated Hospital of Nanjing University Medical School, The First people's Hospital of Yancheng, Jiangsu, China","institution_ids":["https://openalex.org/I4210119554","https://openalex.org/I199305430"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100775950","display_name":"He He","orcid":"https://orcid.org/0000-0002-1513-3987"},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao He","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134570167","display_name":"Minglun Li","orcid":null},"institutions":[{"id":"https://openalex.org/I4210117663","display_name":"Klinikum L\u00fcneburg","ror":"https://ror.org/02k57ty04","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210117663"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Minglun Li","raw_affiliation_strings":["Department of Radiation Oncology, Hospital L\u00fcneburg, L\u00fcneburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Hospital L\u00fcneburg, L\u00fcneburg, Germany","institution_ids":["https://openalex.org/I4210117663"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134606348","display_name":"Zhankui Jia","orcid":null},"institutions":[{"id":"https://openalex.org/I4210156804","display_name":"First Affiliated Hospital of Zhengzhou University","ror":"https://ror.org/056swr059","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156804"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhankui Jia","raw_affiliation_strings":["Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. jiazhankui@126.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China. jiazhankui@126.com","institution_ids":["https://openalex.org/I4210156804"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134618650","display_name":"Xu Gao","orcid":null},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xu Gao","raw_affiliation_strings":["Department of Urology, Changhai Hospital, Second Military Medical University (Naval Medical University), Shanghai, China. gaoxu.changhai@foxmail.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Changhai Hospital, Second Military Medical University (Naval Medical University), Shanghai, China. gaoxu.changhai@foxmail.com","institution_ids":["https://openalex.org/I177933477","https://openalex.org/I4210115928"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039085769","display_name":"Fubo Wang","orcid":"https://orcid.org/0000-0002-2209-9932"},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fubo Wang","raw_affiliation_strings":["Center for Genomic and Personalized Medicine, Guangxi key Laboratory for Genomic and Personalized Medicine, University Engineering Research Center of Digital Medicine and Healthcare, School of Life Science, Guangxi Medical University, Nanning, Guangxi, China. wangfubo@gxmu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genomic and Personalized Medicine, Guangxi key Laboratory for Genomic and Personalized Medicine, University Engineering Research Center of Digital Medicine and Healthcare, School of Life Science, Guangxi Medical University, Nanning, Guangxi, China. wangfubo@gxmu.edu.cn","institution_ids":["https://openalex.org/I160354086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5134594180","display_name":"Guangtao Zhai","orcid":null},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210100255","display_name":"Beijing Academy of Artificial Intelligence","ror":"https://ror.org/016a74861","country_code":"CN","type":"other","lineage":["https://openalex.org/I4210100255"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guangtao Zhai","raw_affiliation_strings":["Institute of Image Communication and Network Engineering, Shanghai Jiao Tong University, Shanghai, China. zhaiguangtao@sjtu.edu.cn","Shanghai Artificial Intelligence Laboratory, Shanghai, China. zhaiguangtao@sjtu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Image Communication and Network Engineering, Shanghai Jiao Tong University, Shanghai, China. zhaiguangtao@sjtu.edu.cn","institution_ids":["https://openalex.org/I183067930"]},{"raw_affiliation_string":"Shanghai Artificial Intelligence Laboratory, Shanghai, China. zhaiguangtao@sjtu.edu.cn","institution_ids":["https://openalex.org/I4210100255"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5134609539","display_name":"Bin Xu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210097066","display_name":"Shanghai Ninth People's Hospital","ror":"https://ror.org/010826a91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210097066"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bin Xu","raw_affiliation_strings":["Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. chxb2004@shsmu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. chxb2004@shsmu.edu.cn","institution_ids":["https://openalex.org/I4210097066"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5134609539"],"corresponding_institution_ids":["https://openalex.org/I4210097066"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":7.972,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.9716496,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"9","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.17980000376701355,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.17980000376701355,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.149399995803833,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.12759999930858612,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prostate-cancer","display_name":"Prostate cancer","score":0.8278999924659729},{"id":"https://openalex.org/keywords/multimodal-therapy","display_name":"Multimodal therapy","score":0.48159998655319214},{"id":"https://openalex.org/keywords/cohort","display_name":"Cohort","score":0.4618000090122223},{"id":"https://openalex.org/keywords/clinical-practice","display_name":"Clinical Practice","score":0.4537999927997589},{"id":"https://openalex.org/keywords/prostate-specific-antigen","display_name":"Prostate-specific antigen","score":0.352400004863739},{"id":"https://openalex.org/keywords/principal-component-analysis","display_name":"Principal component analysis","score":0.3418000042438507},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.3411000072956085}],"concepts":[{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.8278999924659729},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6230000257492065},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5573999881744385},{"id":"https://openalex.org/C4441509","wikidata":"https://www.wikidata.org/wiki/Q6418787","display_name":"Multimodal therapy","level":2,"score":0.48159998655319214},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.4618000090122223},{"id":"https://openalex.org/C2779974597","wikidata":"https://www.wikidata.org/wiki/Q28448986","display_name":"Clinical Practice","level":2,"score":0.4537999927997589},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3682999908924103},{"id":"https://openalex.org/C2781406297","wikidata":"https://www.wikidata.org/wiki/Q409450","display_name":"Prostate-specific antigen","level":4,"score":0.352400004863739},{"id":"https://openalex.org/C27438332","wikidata":"https://www.wikidata.org/wiki/Q2873","display_name":"Principal component analysis","level":2,"score":0.3418000042438507},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3411000072956085},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.33899998664855957},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3375999927520752},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.3116999864578247},{"id":"https://openalex.org/C3018822202","wikidata":"https://www.wikidata.org/wiki/Q1324077","display_name":"Patient data","level":2,"score":0.3009999990463257},{"id":"https://openalex.org/C2983449737","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Clinical diagnosis","level":2,"score":0.30000001192092896},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.2890999913215637},{"id":"https://openalex.org/C3019813237","wikidata":"https://www.wikidata.org/wiki/Q65089264","display_name":"Model validation","level":2,"score":0.28600001335144043},{"id":"https://openalex.org/C168167062","wikidata":"https://www.wikidata.org/wiki/Q1117970","display_name":"Component (thermodynamics)","level":2,"score":0.28299999237060547},{"id":"https://openalex.org/C2989179672","wikidata":"https://www.wikidata.org/wiki/Q6806500","display_name":"Clinical decision making","level":2,"score":0.26969999074935913},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25110000371932983}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-026-02670-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02670-x","pdf_url":"https://www.nature.com/articles/s41746-026-02670-x_reference.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:42034911","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42034911","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:bfb8a7a29a114867aba58dd6828e6f2b","is_oa":false,"landing_page_url":"https://doaj.org/article/bfb8a7a29a114867aba58dd6828e6f2b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 9, Iss 1 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13324722","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13324722/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-026-02670-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02670-x","pdf_url":"https://www.nature.com/articles/s41746-026-02670-x_reference.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Quality Education","score":0.6336309909820557,"id":"https://metadata.un.org/sdg/4"}],"awards":[{"id":"https://openalex.org/G3335513644","display_name":null,"funder_award_id":"M-0171","funder_id":"https://openalex.org/F4320326177","funder_display_name":"Chinesisch-Deutsche Zentrum f\u00fcr Wissenschaftsf\u00f6rderung"},{"id":"https://openalex.org/G4280597270","display_name":null,"funder_award_id":"2021015","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5032025657","display_name":null,"funder_award_id":"M-0171","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G6841327762","display_name":null,"funder_award_id":"62501337","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8668751174","display_name":null,"funder_award_id":"62225112","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320326177","display_name":"Chinesisch-Deutsche Zentrum f\u00fcr Wissenschaftsf\u00f6rderung","ror":"https://ror.org/03ny8r668"},{"id":"https://openalex.org/F4320327301","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7155640318.pdf","grobid_xml":"https://content.openalex.org/works/W7155640318.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"Accurate":[0],"prostate":[1],"cancer":[2],"(PCa)":[3],"diagnosis":[4,121],"remains":[5],"difficult":[6],"because":[7],"of":[8,14,57,70,100],"tumor":[9],"heterogeneity":[10],"and":[11,35,50,122],"the":[12,103],"challenge":[13],"integrating":[15],"multimodal":[16,23,127],"clinical":[17,37,111],"information.":[18],"We":[19],"developed":[20],"Prost-LM,":[21],"a":[22,40,53],"large":[24,54],"language":[25],"model":[26,104],"that":[27],"jointly":[28],"embeds":[29],"MRI-derived":[30],"features,":[31],"numerical":[32],"PSA":[33],"values,":[34],"free-text":[36],"reports":[38],"into":[39],"unified":[41],"semantic":[42],"space":[43],"to":[44,109],"enable":[45],"deep":[46],"cross-modal":[47],"reasoning.":[48],"Trained":[49],"validated":[51],"on":[52],"multi-center":[55],"cohort":[56],"3940":[58],"patients,":[59],"Prost-LM":[60,96,116],"achieved":[61],"strong":[62],"diagnostic":[63,107],"performance,":[64],"with":[65],"an":[66,98],"internal":[67],"validation":[68],"AUC":[69,99],"0.954":[71],"for":[72],"distinguishing":[73],"PCa":[74,91,120],"from":[75],"benign":[76],"conditions,":[77],"outperforming":[78],"MRI-only":[79],"models":[80],"(AUC":[81],"=":[82],"0.868,":[83],"P":[84],"<":[85],"0.001).":[86],"For":[87],"detecting":[88],"clinically":[89],"significant":[90],"(Gleason":[92],"score":[93],"\u2265":[94],"7),":[95],"reached":[97],"0.955.":[101],"Additionally,":[102],"provides":[105],"interpretable":[106],"decisions":[108],"support":[110,123],"verification.":[112],"These":[113],"results":[114],"suggest":[115],"can":[117],"improve":[118],"automated":[119],"precision":[124],"oncology":[125],"through":[126],"AI.":[128]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-07-17T09:13:05.818461","created_date":"2026-04-26T00:00:00"}