{"id":"https://openalex.org/W7154828971","doi":"https://doi.org/10.1038/s41746-026-02628-z","title":"Patch-to-slide fusion deep learning model for histological diagnosis of early pregnancy loss including hydatidiform mole","display_name":"Patch-to-slide fusion deep learning model for histological diagnosis of early pregnancy loss including hydatidiform mole","publication_year":2026,"publication_date":"2026-04-18","ids":{"openalex":"https://openalex.org/W7154828971","doi":"https://doi.org/10.1038/s41746-026-02628-z","pmid":"https://pubmed.ncbi.nlm.nih.gov/42000889"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-026-02628-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02628-z","pdf_url":"https://www.nature.com/articles/s41746-026-02628-z.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-026-02628-z.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5133945914","display_name":"Yating Zhao","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yating Zhao","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133964276","display_name":"Xinhui He","orcid":null},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xinhui He","raw_affiliation_strings":["Institute of Advanced Digital Technologies and Instrumentation, Zhejiang University, Hangzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Advanced Digital Technologies and Instrumentation, Zhejiang University, Hangzhou, P.R. China","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133945036","display_name":"Xin Ye","orcid":null},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xin Ye","raw_affiliation_strings":["Institute of Advanced Digital Technologies and Instrumentation, Zhejiang University, Hangzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Advanced Digital Technologies and Instrumentation, Zhejiang University, Hangzhou, P.R. China","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133925098","display_name":"Zhe Wang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhe Wang","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133919956","display_name":"Bo Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bo Huang","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133950936","display_name":"Jiaqi Ning","orcid":null},"institutions":[{"id":"https://openalex.org/I1328775524","display_name":"Zhejiang Sci-Tech University","ror":"https://ror.org/03893we55","country_code":"CN","type":"education","lineage":["https://openalex.org/I1328775524"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiaqi Ning","raw_affiliation_strings":["Institute of Advanced Digital Technologies and Instrumentation, Zhejiang University, Hangzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Advanced Digital Technologies and Instrumentation, Zhejiang University, Hangzhou, P.R. China","institution_ids":["https://openalex.org/I1328775524"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133940523","display_name":"Limeng Cai","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Limeng Cai","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024896098","display_name":"Peilin Han","orcid":"https://orcid.org/0000-0001-6401-3255"},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Peilin Han","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133937951","display_name":"Huifang Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huifang Zhang","raw_affiliation_strings":["Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133938594","display_name":"Hao Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I4210114400","display_name":"Hangzhou Women\u2019s Hospital","ror":"https://ror.org/021n4pk58","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210114400"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Chen","raw_affiliation_strings":["Department of Pathology, Hangzhou Women's Hospital, Hangzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Hangzhou Women's Hospital, Hangzhou, P.R. China","institution_ids":["https://openalex.org/I4210114400"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047117959","display_name":"Xiangang Yin","orcid":null},"institutions":[{"id":"https://openalex.org/I13591777","display_name":"University of Nottingham Ningbo China","ror":"https://ror.org/03y4dt428","country_code":"CN","type":"education","lineage":["https://openalex.org/I13591777","https://openalex.org/I142263535"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiangang Yin","raw_affiliation_strings":["Ningbo Clinical Pathology Diagnosis Centre, Ningbo City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ningbo Clinical Pathology Diagnosis Centre, Ningbo City, P.R. China","institution_ids":["https://openalex.org/I13591777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133963358","display_name":"Jie Dong","orcid":null},"institutions":[{"id":"https://openalex.org/I4210156985","display_name":"Huzhou Women and Children's Hospital","ror":"https://ror.org/04mrmjg19","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210156985"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Dong","raw_affiliation_strings":["Department of Gynecology, Huzhou Maternity & Child Health Care Hospital, Huzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, Huzhou Maternity & Child Health Care Hospital, Huzhou, P.R. China","institution_ids":["https://openalex.org/I4210156985"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133942478","display_name":"Ping Duan","orcid":null},"institutions":[{"id":"https://openalex.org/I27781120","display_name":"Wenzhou Medical University","ror":"https://ror.org/00rd5t069","country_code":"CN","type":"education","lineage":["https://openalex.org/I27781120"]},{"id":"https://openalex.org/I4210099512","display_name":"Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University","ror":"https://ror.org/0156rhd17","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099512"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Duan","raw_affiliation_strings":["Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynecology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, P.R. China","institution_ids":["https://openalex.org/I4210099512","https://openalex.org/I27781120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041909632","display_name":"Huafeng Shou","orcid":null},"institutions":[{"id":"https://openalex.org/I4210165441","display_name":"Hangzhou Medical College","ror":"https://ror.org/05gpas306","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210165441"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huafeng Shou","raw_affiliation_strings":["Department of Gynecology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou, P.R. China","institution_ids":["https://openalex.org/I4210165441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101860663","display_name":"Qingmei Han","orcid":"https://orcid.org/0000-0002-5892-5028"},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingmei Han","raw_affiliation_strings":["Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133945767","display_name":"Kai Yan","orcid":null},"institutions":[{"id":"https://openalex.org/I4210137217","display_name":"Women's Hospital, School of Medicine, Zhejiang University","ror":"https://ror.org/042t7yh44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210137217"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Kai Yan","raw_affiliation_strings":["Department of Reproductive Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Reproductive Genetics, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China","institution_ids":["https://openalex.org/I4210137217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133956985","display_name":"Jing Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Zhang","raw_affiliation_strings":["Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133924075","display_name":"Min Hu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210119757","display_name":"Jinhua Academy of Agricultural Sciences","ror":"https://ror.org/02n6fv369","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210119757"]},{"id":"https://openalex.org/I4210121675","display_name":"Guang Fu Hospital","ror":"https://ror.org/02ec9na09","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121675"]},{"id":"https://openalex.org/I4210162045","display_name":"Jinhua Central Hospital","ror":"https://ror.org/04z13ha89","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210162045"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Min Hu","raw_affiliation_strings":["Department of Gynecology, Jinhua Hospital of Zhejiang University, Jinhua, P.R. China","Department of Gynecology, Jinhua Maternity and Child Health Care Hospital, Jinhua Women's and Children's Hospital, Jinhua, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, Jinhua Hospital of Zhejiang University, Jinhua, P.R. China","institution_ids":["https://openalex.org/I4210162045","https://openalex.org/I4210119757","https://openalex.org/I4210121675"]},{"raw_affiliation_string":"Department of Gynecology, Jinhua Maternity and Child Health Care Hospital, Jinhua Women's and Children's Hospital, Jinhua, P.R. China","institution_ids":["https://openalex.org/I4210119757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133931374","display_name":"Ruiqi Sun","orcid":null},"institutions":[{"id":"https://openalex.org/I4210148790","display_name":"Hangzhou First People's Hospital","ror":"https://ror.org/05pwsw714","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210148790"]},{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ruiqi Sun","raw_affiliation_strings":["Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China","institution_ids":["https://openalex.org/I4210166576","https://openalex.org/I4210148790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133933976","display_name":"Qihong Wan","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qihong Wan","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133929325","display_name":"Xiupu Liu","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiupu Liu","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133929665","display_name":"Qiwei Zheng","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qiwei Zheng","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133954284","display_name":"Wanting Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wanting Huang","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133922005","display_name":"Haixia Luo","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haixia Luo","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133946035","display_name":"Jue Xie","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jue Xie","raw_affiliation_strings":["Department of Blood Transfusion, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China. zyyyxj2011@zju.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Blood Transfusion, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, P.R. China. zyyyxj2011@zju.edu.cn","institution_ids":["https://openalex.org/I4210166576"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133961138","display_name":"Xiaofei Zhang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210137217","display_name":"Women's Hospital, School of Medicine, Zhejiang University","ror":"https://ror.org/042t7yh44","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210137217"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaofei Zhang","raw_affiliation_strings":["Department of Pathology, The Zhejiang University School of Medicine Women's Hospital, Hangzhou, P.R. China. pathozxf@zju.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, The Zhejiang University School of Medicine Women's Hospital, Hangzhou, P.R. China. pathozxf@zju.edu.cn","institution_ids":["https://openalex.org/I4210137217"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5133943708","display_name":"Xiang Tian","orcid":null},"institutions":[{"id":"https://openalex.org/I76130692","display_name":"Zhejiang University","ror":"https://ror.org/00a2xv884","country_code":"CN","type":"education","lineage":["https://openalex.org/I76130692"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiang Tian","raw_affiliation_strings":["Institute of Advanced Digital Technologies and Instrumentation, Zhejiang University, Hangzhou, P.R. China. tianx@zju.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Advanced Digital Technologies and Instrumentation, Zhejiang University, Hangzhou, P.R. China. tianx@zju.edu.cn","institution_ids":["https://openalex.org/I76130692"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5133926611","display_name":"Jianhua Qian","orcid":null},"institutions":[{"id":"https://openalex.org/I4210166576","display_name":"First Affiliated Hospital Zhejiang University","ror":"https://ror.org/05m1p5x56","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210166576"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jianhua Qian","raw_affiliation_strings":["Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China. qianjianhua@zju.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gynecology, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou City, P.R. China. qianjianhua@zju.edu.cn","institution_ids":["https://openalex.org/I4210166576"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5133926611","https://openalex.org/A5133943708","https://openalex.org/A5133946035","https://openalex.org/A5133961138"],"corresponding_institution_ids":["https://openalex.org/I4210137217","https://openalex.org/I4210166576","https://openalex.org/I76130692"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.47390312,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12587","display_name":"Gestational Trophoblastic Disease Studies","score":0.9921000003814697,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12587","display_name":"Gestational Trophoblastic Disease Studies","score":0.9921000003814697,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12096","display_name":"Ectopic Pregnancy Diagnosis and Management","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/early-pregnancy-factor","display_name":"Early pregnancy factor","score":0.6223999857902527},{"id":"https://openalex.org/keywords/early-pregnancy-loss","display_name":"Early Pregnancy Loss","score":0.527999997138977},{"id":"https://openalex.org/keywords/pregnancy","display_name":"Pregnancy","score":0.4336000084877014},{"id":"https://openalex.org/keywords/deep-learning","display_name":"Deep learning","score":0.40619999170303345},{"id":"https://openalex.org/keywords/fusion","display_name":"Fusion","score":0.2802000045776367}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7311000227928162},{"id":"https://openalex.org/C68557331","wikidata":"https://www.wikidata.org/wiki/Q14865007","display_name":"Early pregnancy factor","level":4,"score":0.6223999857902527},{"id":"https://openalex.org/C2909731803","wikidata":"https://www.wikidata.org/wiki/Q28693","display_name":"Early Pregnancy Loss","level":4,"score":0.527999997138977},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.47760000824928284},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.4336000084877014},{"id":"https://openalex.org/C29456083","wikidata":"https://www.wikidata.org/wiki/Q1221899","display_name":"Gynecology","level":1,"score":0.4203999936580658},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.40619999170303345},{"id":"https://openalex.org/C158525013","wikidata":"https://www.wikidata.org/wiki/Q2593739","display_name":"Fusion","level":2,"score":0.2802000045776367},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.23489999771118164},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.22139999270439148}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-026-02628-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02628-z","pdf_url":"https://www.nature.com/articles/s41746-026-02628-z.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:42000889","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/42000889","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:9f9c96e0d22b4af098994718c91bdb70","is_oa":false,"landing_page_url":"https://doaj.org/article/9f9c96e0d22b4af098994718c91bdb70","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 9, Iss 1 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13275801","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13275801/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-026-02628-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02628-z","pdf_url":"https://www.nature.com/articles/s41746-026-02628-z.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1886326360","display_name":null,"funder_award_id":"2023YFC2705801","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G3490326018","display_name":null,"funder_award_id":"2025C02115","funder_id":"https://openalex.org/F8142712028","funder_display_name":"Key Research and Development Program of Zhejiang Province"},{"id":"https://openalex.org/G6457895994","display_name":null,"funder_award_id":"82071665","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8827284285","display_name":null,"funder_award_id":"82371669","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null},{"id":"https://openalex.org/F8142712028","display_name":"Key Research and Development Program of Zhejiang Province","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7154828971.pdf","grobid_xml":"https://content.openalex.org/works/W7154828971.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1513797916","https://openalex.org/W1993866784","https://openalex.org/W2027123781","https://openalex.org/W2028063483","https://openalex.org/W2029916401","https://openalex.org/W2062571119","https://openalex.org/W2132162500","https://openalex.org/W2144623119","https://openalex.org/W2194775991","https://openalex.org/W2343051383","https://openalex.org/W2413833375","https://openalex.org/W2498651201","https://openalex.org/W2902815834","https://openalex.org/W2952481429","https://openalex.org/W2956228567","https://openalex.org/W2964930844","https://openalex.org/W2983301251","https://openalex.org/W2985735457","https://openalex.org/W2995276890","https://openalex.org/W3115168802","https://openalex.org/W3134334167","https://openalex.org/W3135547872","https://openalex.org/W3211647829","https://openalex.org/W3216119570","https://openalex.org/W4200071875","https://openalex.org/W4293199755","https://openalex.org/W4295754180","https://openalex.org/W4317478289","https://openalex.org/W4322754504","https://openalex.org/W4366818789","https://openalex.org/W4386693652","https://openalex.org/W4399897259","https://openalex.org/W4400949331","https://openalex.org/W4402220065","https://openalex.org/W7116990507"],"related_works":[],"abstract_inverted_index":{"Distinguishing":[0],"histological":[1,38],"subtypes":[2],"of":[3,42,87,91,99,103],"early":[4],"pregnancy":[5],"loss":[6],"is":[7],"crucial":[8],"for":[9,62,137],"clinical":[10],"practice.":[11],"Current":[12],"gold":[13],"standards":[14],"combining":[15],"pathological":[16],"and":[17,45,50,65,79,89,97,122,124,140],"molecular":[18],"profiling":[19],"are":[20],"costly,":[21],"limiting":[22],"implementation.":[23],"We":[24],"developed":[25],"a":[26],"patch-to-slide":[27],"fusion":[28],"artificial":[29],"intelligence":[30],"(AI)":[31],"model":[32,83,119],"with":[33,101],"adaptive":[34],"masking":[35],"to":[36],"predict":[37],"diagnosis.":[39],"A":[40],"total":[41],"1380":[43],"haematoxylin":[44,121],"eosin":[46,123],"stained,":[47],"1057":[48],"p57":[49,125],"646":[51],"Ki-67":[52],"immunohistochemistry":[53],"stained":[54],"whole-slide":[55],"images":[56],"from":[57],"1287":[58],"patients":[59],"were":[60,68],"used":[61],"multicenter":[63],"development":[64,95],"validation.":[66],"Cases":[67],"classified":[69],"as":[70],"complete":[71],"hydatidiform":[72,75],"moles,":[73,76],"partial":[74],"hydropic":[77],"abortion,":[78],"normal":[80],"control.":[81],"The":[82,117],"achieved":[84],"slide-level":[85],"accuracy":[86,98],"0.843":[88],"AUROC":[90,102],"0.959":[92],"in":[93,105],"the":[94],"test,":[96],"0.801":[100],"0.930":[104],"independent":[106],"testing.":[107],"AI-assisted":[108],"diagnosis":[109],"significantly":[110],"improved":[111],"pathologist":[112],"performance":[113],"(p":[114],"<":[115],"0.05).":[116],"multi-stain":[118],"integrating":[120],"outperformed":[126],"single-stain":[127],"models.":[128],"This":[129],"tool":[130],"may":[131],"improve":[132],"diagnostic":[133],"precision,":[134],"assist":[135],"triage":[136],"genetic":[138],"testing,":[139],"reduce":[141],"costs.":[142]},"counts_by_year":[],"updated_date":"2026-06-19T15:47:20.252518","created_date":"2026-04-19T00:00:00"}