{"id":"https://openalex.org/W7129012204","doi":"https://doi.org/10.1038/s41746-026-02430-x","title":"Health economic simulation modeling of an AI-enabled clinical decision support system for coronary revascularization","display_name":"Health economic simulation modeling of an AI-enabled clinical decision support system for coronary revascularization","publication_year":2026,"publication_date":"2026-02-16","ids":{"openalex":"https://openalex.org/W7129012204","doi":"https://doi.org/10.1038/s41746-026-02430-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/41699068"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-026-02430-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02430-x","pdf_url":"https://www.nature.com/articles/s41746-026-02430-x_reference.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-026-02430-x_reference.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061024562","display_name":"Tom Mullie","orcid":null},"institutions":[{"id":"https://openalex.org/I2801827850","display_name":"Alberta Bible College","ror":"https://ror.org/00fj6he94","country_code":"CA","type":"education","lineage":["https://openalex.org/I2801827850"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Tom Mullie","raw_affiliation_strings":["Acute Care Alberta, Calgary, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Acute Care Alberta, Calgary, AB, Canada","institution_ids":["https://openalex.org/I2801827850"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012965436","display_name":"Arjun Puri","orcid":"https://orcid.org/0000-0003-1122-1442"},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Arjun Puri","raw_affiliation_strings":["Data Intelligence for Health Lab, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada","Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Data Intelligence for Health Lab, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054080628","display_name":"Emma Bogner","orcid":null},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Emma Bogner","raw_affiliation_strings":["Data Intelligence for Health Lab, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada","Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Data Intelligence for Health Lab, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035288402","display_name":"Bryan Har","orcid":"https://orcid.org/0000-0003-2760-8967"},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I56478863","display_name":"Libin Cardiovascular Institute of Alberta","ror":"https://ror.org/02qthww36","country_code":"CA","type":"facility","lineage":["https://openalex.org/I56478863"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Bryan Har","raw_affiliation_strings":["Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada","Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada","institution_ids":["https://openalex.org/I56478863","https://openalex.org/I168635309"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090747924","display_name":"Colm J. Murphy","orcid":null},"institutions":[{"id":"https://openalex.org/I4210147836","display_name":"Collaborative Drug Discovery (United States)","ror":"https://ror.org/04b4sq284","country_code":"US","type":"company","lineage":["https://openalex.org/I4210147836"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Colm J. Murphy","raw_affiliation_strings":["Golden State Heart and Vascular, Burlingame, CA, US"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Golden State Heart and Vascular, Burlingame, CA, US","institution_ids":["https://openalex.org/I4210147836"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126096961","display_name":"Robert C. Welsh","orcid":null},"institutions":[{"id":"https://openalex.org/I154425047","display_name":"University of Alberta","ror":"https://ror.org/0160cpw27","country_code":"CA","type":"education","lineage":["https://openalex.org/I154425047"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Robert C. Welsh","raw_affiliation_strings":["Mazankowski Alberta Heart Institute, Division of Cardiology, University of Alberta, Edmonton, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mazankowski Alberta Heart Institute, Division of Cardiology, University of Alberta, Edmonton, AB, Canada","institution_ids":["https://openalex.org/I154425047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126095921","display_name":"Benjamin Tyrrell","orcid":null},"institutions":[{"id":"https://openalex.org/I4210098043","display_name":"Royal Alexandra Hospital","ror":"https://ror.org/00wyx7h61","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I126859394","https://openalex.org/I4210098043"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Benjamin Tyrrell","raw_affiliation_strings":["Royal Alexandra Hospital, Edmonton, AB, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Royal Alexandra Hospital, Edmonton, AB, Canada","institution_ids":["https://openalex.org/I4210098043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5126081726","display_name":"Christopher L. F. Sun","orcid":null},"institutions":[{"id":"https://openalex.org/I153718931","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16","country_code":"CA","type":"education","lineage":["https://openalex.org/I153718931"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Christopher L. F. Sun","raw_affiliation_strings":["Telfer School of Management, University of Ottawa, Ottawa, ON, Canada","University of Ottawa Heart Institute, Ottawa, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Telfer School of Management, University of Ottawa, Ottawa, ON, Canada","institution_ids":["https://openalex.org/I153718931"]},{"raw_affiliation_string":"University of Ottawa Heart Institute, Ottawa, ON, Canada","institution_ids":["https://openalex.org/I153718931"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047889959","display_name":"Lee Jc","orcid":"https://orcid.org/0000-0002-1502-8693"},"institutions":[{"id":"https://openalex.org/I168635309","display_name":"University of Calgary","ror":"https://ror.org/03yjb2x39","country_code":"CA","type":"education","lineage":["https://openalex.org/I168635309"]},{"id":"https://openalex.org/I56478863","display_name":"Libin Cardiovascular Institute of Alberta","ror":"https://ror.org/02qthww36","country_code":"CA","type":"facility","lineage":["https://openalex.org/I56478863"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Joon Lee","raw_affiliation_strings":["Data Intelligence for Health Lab, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. joon.lee@ucalgary.ca","Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. joon.lee@ucalgary.ca","Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. joon.lee@ucalgary.ca","Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. joon.lee@ucalgary.ca"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Data Intelligence for Health Lab, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. joon.lee@ucalgary.ca","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. joon.lee@ucalgary.ca","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. joon.lee@ucalgary.ca","institution_ids":["https://openalex.org/I168635309"]},{"raw_affiliation_string":"Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada. joon.lee@ucalgary.ca","institution_ids":["https://openalex.org/I56478863"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5047889959"],"corresponding_institution_ids":["https://openalex.org/I168635309","https://openalex.org/I56478863"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13807424,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"9","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.37959998846054077,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.37959998846054077,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10675","display_name":"Mechanical Circulatory Support Devices","score":0.13339999318122864,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.05460000038146973,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/revascularization","display_name":"Revascularization","score":0.6245999932289124},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"Coronary artery disease","score":0.5849000215530396},{"id":"https://openalex.org/keywords/bypass-grafting","display_name":"Bypass grafting","score":0.5115000009536743},{"id":"https://openalex.org/keywords/decision-support-system","display_name":"Decision support system","score":0.5072000026702881},{"id":"https://openalex.org/keywords/economic-evaluation","display_name":"Economic evaluation","score":0.4909000098705292},{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention","display_name":"Percutaneous coronary intervention","score":0.43290001153945923},{"id":"https://openalex.org/keywords/clinical-decision-support-system","display_name":"Clinical decision support system","score":0.41519999504089355},{"id":"https://openalex.org/keywords/economic-model","display_name":"Economic model","score":0.3968000113964081},{"id":"https://openalex.org/keywords/coronary-disease","display_name":"Coronary disease","score":0.3765999972820282},{"id":"https://openalex.org/keywords/quality-adjusted-life-year","display_name":"Quality-adjusted life year","score":0.3752000033855438}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7623000144958496},{"id":"https://openalex.org/C2779464278","wikidata":"https://www.wikidata.org/wiki/Q7317735","display_name":"Revascularization","level":3,"score":0.6245999932289124},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.5849000215530396},{"id":"https://openalex.org/C3017915907","wikidata":"https://www.wikidata.org/wiki/Q186020","display_name":"Bypass grafting","level":3,"score":0.5115000009536743},{"id":"https://openalex.org/C107327155","wikidata":"https://www.wikidata.org/wiki/Q330268","display_name":"Decision support system","level":2,"score":0.5072000026702881},{"id":"https://openalex.org/C2776125615","wikidata":"https://www.wikidata.org/wiki/Q18391886","display_name":"Economic evaluation","level":2,"score":0.4909000098705292},{"id":"https://openalex.org/C2780400711","wikidata":"https://www.wikidata.org/wiki/Q2008344","display_name":"Percutaneous coronary intervention","level":3,"score":0.43290001153945923},{"id":"https://openalex.org/C63527458","wikidata":"https://www.wikidata.org/wiki/Q5133829","display_name":"Clinical decision support system","level":3,"score":0.41519999504089355},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.40389999747276306},{"id":"https://openalex.org/C119693030","wikidata":"https://www.wikidata.org/wiki/Q2180497","display_name":"Economic model","level":2,"score":0.3968000113964081},{"id":"https://openalex.org/C2994432733","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary disease","level":3,"score":0.3765999972820282},{"id":"https://openalex.org/C64332521","wikidata":"https://www.wikidata.org/wiki/Q614165","display_name":"Quality-adjusted life year","level":3,"score":0.3752000033855438},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.358599990606308},{"id":"https://openalex.org/C127454912","wikidata":"https://www.wikidata.org/wiki/Q942582","display_name":"Cost\u2013benefit analysis","level":2,"score":0.35589998960494995},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.34450000524520874},{"id":"https://openalex.org/C2985697011","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economic analysis","level":2,"score":0.3393999934196472},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.3391000032424927},{"id":"https://openalex.org/C2994510025","wikidata":"https://www.wikidata.org/wiki/Q179661","display_name":"Medical therapy","level":2,"score":0.32519999146461487},{"id":"https://openalex.org/C145096142","wikidata":"https://www.wikidata.org/wiki/Q5333450","display_name":"Economic cost","level":2,"score":0.3206000030040741},{"id":"https://openalex.org/C188897","wikidata":"https://www.wikidata.org/wiki/Q5333508","display_name":"Economic impact analysis","level":2,"score":0.31290000677108765},{"id":"https://openalex.org/C3020452639","wikidata":"https://www.wikidata.org/wiki/Q454812","display_name":"Clinical judgment","level":2,"score":0.310699999332428},{"id":"https://openalex.org/C2780813298","wikidata":"https://www.wikidata.org/wiki/Q2071287","display_name":"Percutaneous","level":2,"score":0.30959999561309814},{"id":"https://openalex.org/C2780409771","wikidata":"https://www.wikidata.org/wiki/Q2624498","display_name":"Life support","level":2,"score":0.30480000376701355},{"id":"https://openalex.org/C2776291640","wikidata":"https://www.wikidata.org/wiki/Q2912517","display_name":"Value (mathematics)","level":2,"score":0.3043000102043152},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.2976999878883362},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.289000004529953},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.27559998631477356},{"id":"https://openalex.org/C3018906752","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary heart disease","level":2,"score":0.275299996137619},{"id":"https://openalex.org/C186116695","wikidata":"https://www.wikidata.org/wiki/Q5249226","display_name":"Decision analysis","level":2,"score":0.2678999900817871},{"id":"https://openalex.org/C2775901492","wikidata":"https://www.wikidata.org/wiki/Q186020","display_name":"Coronary artery bypass surgery","level":3,"score":0.26669999957084656},{"id":"https://openalex.org/C2983241795","wikidata":"https://www.wikidata.org/wiki/Q6806500","display_name":"Medical decision making","level":2,"score":0.2619999945163727},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.259799987077713},{"id":"https://openalex.org/C3019080777","wikidata":"https://www.wikidata.org/wiki/Q1754768","display_name":"Cost effectiveness","level":2,"score":0.25690001249313354},{"id":"https://openalex.org/C207386681","wikidata":"https://www.wikidata.org/wiki/Q451323","display_name":"Derivation","level":3,"score":0.25519999861717224},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.2549999952316284},{"id":"https://openalex.org/C2989179672","wikidata":"https://www.wikidata.org/wiki/Q6806500","display_name":"Clinical decision making","level":2,"score":0.251800000667572}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-026-02430-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02430-x","pdf_url":"https://www.nature.com/articles/s41746-026-02430-x_reference.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:41699068","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41699068","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:cb110974970f4141a7af515619a1be76","is_oa":true,"landing_page_url":"https://doaj.org/article/cb110974970f4141a7af515619a1be76","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 9, Iss 1 (2026)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:13022373","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC13022373/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-026-02430-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-026-02430-x","pdf_url":"https://www.nature.com/articles/s41746-026-02430-x_reference.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G5990209255","display_name":null,"funder_award_id":"212200473","funder_id":"https://openalex.org/F4320325651","funder_display_name":"Alberta Innovates"},{"id":"https://openalex.org/G7836683790","display_name":null,"funder_award_id":"PJT 178027","funder_id":"https://openalex.org/F4320334506","funder_display_name":"Canadian Institutes of Health Research"}],"funders":[{"id":"https://openalex.org/F4320325651","display_name":"Alberta Innovates","ror":null},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7129012204.pdf","grobid_xml":"https://content.openalex.org/works/W7129012204.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W1946152282","https://openalex.org/W1995314235","https://openalex.org/W2031744162","https://openalex.org/W2098674170","https://openalex.org/W2105345588","https://openalex.org/W2117419474","https://openalex.org/W2143368051","https://openalex.org/W2160414137","https://openalex.org/W2786107187","https://openalex.org/W2801677840","https://openalex.org/W2994638107","https://openalex.org/W2996102097","https://openalex.org/W3092494313","https://openalex.org/W3118632980","https://openalex.org/W3206003576","https://openalex.org/W3211501701","https://openalex.org/W4200376377","https://openalex.org/W4210661901","https://openalex.org/W4224267054","https://openalex.org/W4308635427","https://openalex.org/W4366235587","https://openalex.org/W4367173225","https://openalex.org/W4380345421","https://openalex.org/W4398615623","https://openalex.org/W4401560185","https://openalex.org/W4407445136"],"related_works":[],"abstract_inverted_index":{"While":[0],"artificial":[1],"intelligence":[2],"(AI)":[3],"models":[4,18],"have":[5],"been":[6,20],"developed":[7],"to":[8,46,75,113,133,135,150,166,168],"support":[9,57],"coronary":[10,40,54,66,69],"revascularization":[11,55],"decision-making,":[12],"health":[13,26,116,177],"economic":[14,27,49,180],"evaluation":[15],"of":[16,51,81,95,107,126,154,182,188],"such":[17],"has":[19],"rare.":[21],"We":[22],"conducted":[23],"a":[24,93,114,129,141],"retrospective":[25],"simulation":[28],"modeling":[29],"study":[30],"using":[31],"real-world":[32],"data":[33],"from":[34,192],"25,942":[35],"adult":[36],"patients":[37],"with":[38,78],"obstructive":[39],"artery":[41,70],"disease":[42],"in":[43,121,140,160,185],"Alberta,":[44],"Canada":[45],"evaluate":[47],"the":[48,155,176,186],"value":[50,181],"an":[52,122,161],"AI-enabled":[53],"decision":[56],"system.":[58],"Clinicians":[59],"deciding":[60],"among":[61],"medical":[62],"therapy":[63],"only,":[64],"percutaneous":[65],"intervention,":[67],"and":[68,83,89,128,196],"bypass":[71],"grafting":[72],"were":[73],"simulated":[74],"be":[76,151],"provided":[77],"AI":[79,146,172],"predictions":[80],"3-":[82],"5-year":[84],"major":[85],"adverse":[86],"cardiovascular":[87],"events":[88],"all-cause":[90],"mortality.":[91],"At":[92],"willingness-to-pay":[94],"$50,000":[96],"per":[97,137,170],"quality":[98],"adjusted":[99],"life":[100],"year":[101],"(QALY),":[102],"as":[103,105],"many":[104],"72.4%":[106],"all":[108],"actual":[109,156],"treatment":[110,183],"decisions":[111,157,184],"shifted":[112],"different":[115],"economically":[117],"optimized":[118],"treatment,":[119],"resulting":[120,159],"average":[123,162],"cost":[124],"saving":[125],"$22,960":[127],"QALY":[130,163],"gain":[131,164],"equivalent":[132,165],"up":[134,167],"$22,439":[136],"patient.":[138,171],"Even":[139],"conservative":[142],"scenario":[143],"where":[144],"clinicians'":[145],"adoption":[147],"was":[148],"assumed":[149],"limited,":[152],"53.2%":[153],"shifted,":[158],"$32,214":[169],"can":[173],"potentially":[174],"optimize":[175],"system":[178],"level":[179],"form":[187],"reduced":[189],"costs":[190],"stemming":[191],"fewer":[193],"future":[194],"complications":[195],"improved":[197],"patient":[198],"outcomes.":[199]},"counts_by_year":[],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2026-02-17T00:00:00"}