{"id":"https://openalex.org/W4416691671","doi":"https://doi.org/10.1038/s41746-025-02164-2","title":"Artificial intelligence-enabled analysis of handheld single-lead electrocardiograms to predict incident atrial fibrillation: an analysis of the VITAL-AF randomized trial","display_name":"Artificial intelligence-enabled analysis of handheld single-lead electrocardiograms to predict incident atrial fibrillation: an analysis of the VITAL-AF randomized trial","publication_year":2025,"publication_date":"2025-11-26","ids":{"openalex":"https://openalex.org/W4416691671","doi":"https://doi.org/10.1038/s41746-025-02164-2","pmid":"https://pubmed.ncbi.nlm.nih.gov/41299008"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-025-02164-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-02164-2","pdf_url":"https://www.nature.com/articles/s41746-025-02164-2_reference.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-025-02164-2_reference.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041028758","display_name":"Shaan Khurshid","orcid":"https://orcid.org/0000-0002-2840-4539"},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1285119806","display_name":"Heart Rhythm Society","ror":"https://ror.org/035m9ft70","country_code":"US","type":"other","lineage":["https://openalex.org/I1285119806"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shaan Khurshid","raw_affiliation_strings":["Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","Telemachus and Irene Demoulas Family Foundation Center for Cardiac Arrhythmias, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Telemachus and Irene Demoulas Family Foundation Center for Cardiac Arrhythmias, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I1285119806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054879244","display_name":"Sam Friedman","orcid":"https://orcid.org/0000-0002-0688-2169"},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sam F. Friedman","raw_affiliation_strings":["Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046469598","display_name":"Mostafa A. Al\u2010Alusi","orcid":"https://orcid.org/0000-0002-9359-1641"},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mostafa A. Al-Alusi","raw_affiliation_strings":["Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","Division of Cardiology, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Division of Cardiology, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020324180","display_name":"Shinwan Kany","orcid":"https://orcid.org/0000-0001-8113-733X"},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I159176309","display_name":"Universit\u00e4t Hamburg","ror":"https://ror.org/00g30e956","country_code":"DE","type":"education","lineage":["https://openalex.org/I159176309"]},{"id":"https://openalex.org/I4210108711","display_name":"University Medical Center Hamburg-Eppendorf","ror":"https://ror.org/01zgy1s35","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"id":"https://openalex.org/I4210127591","display_name":"German Centre for Cardiovascular Research","ror":"https://ror.org/031t5w623","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210127591","https://openalex.org/I4405256427"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Shinwan Kany","raw_affiliation_strings":["Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","Department of Cardiology, University Heart and Vascular Center Hamburg-Eppendorf, Hamburg, Germany","German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/L\u00fcbeck, Hamburg, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Department of Cardiology, University Heart and Vascular Center Hamburg-Eppendorf, Hamburg, Germany","institution_ids":["https://openalex.org/I159176309","https://openalex.org/I4210108711"]},{"raw_affiliation_string":"German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/L\u00fcbeck, Hamburg, Germany","institution_ids":["https://openalex.org/I4210127591"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049857964","display_name":"Thomas Sommers","orcid":"https://orcid.org/0000-0002-1300-8234"},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Sommers","raw_affiliation_strings":["Department of Medicine, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006140547","display_name":"Christopher D. Anderson","orcid":"https://orcid.org/0000-0002-0053-2002"},"institutions":[{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christopher D. Anderson","raw_affiliation_strings":["Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA","Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA","Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]},{"raw_affiliation_string":"Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I1283280774"]},{"raw_affiliation_string":"Henry and Allison McCance Center for Brain Health, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004356613","display_name":"Jennifer E. Ho","orcid":"https://orcid.org/0000-0002-7987-4768"},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer E. Ho","raw_affiliation_strings":["Cardiology Division, Beth Israel Deaconess Medical Center, Boston, MA, USA","Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiology Division, Beth Israel Deaconess Medical Center, Boston, MA, USA","institution_ids":["https://openalex.org/I1316535847"]},{"raw_affiliation_string":"Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107008179","display_name":"David D. McManus","orcid":null},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David D. McManus","raw_affiliation_strings":["Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024099354","display_name":"Leila H. Borowsky","orcid":"https://orcid.org/0000-0001-7498-4450"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leila H. Borowsky","raw_affiliation_strings":["Division of General Internal Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General Internal Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042245461","display_name":"Jeffrey M. Ashburner","orcid":"https://orcid.org/0000-0002-5600-3492"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey M. Ashburner","raw_affiliation_strings":["Division of General Internal Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General Internal Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107906618","display_name":"Steven A. Lubitz","orcid":null},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1285119806","display_name":"Heart Rhythm Society","ror":"https://ror.org/035m9ft70","country_code":"US","type":"other","lineage":["https://openalex.org/I1285119806"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven A. Lubitz","raw_affiliation_strings":["Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","Telemachus and Irene Demoulas Family Foundation Center for Cardiac Arrhythmias, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Telemachus and Irene Demoulas Family Foundation Center for Cardiac Arrhythmias, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I1285119806"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061398003","display_name":"Steven J. Atlas","orcid":"https://orcid.org/0000-0002-2297-9614"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven J. Atlas","raw_affiliation_strings":["Division of General Internal Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General Internal Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084779220","display_name":"Mahnaz Maddah","orcid":"https://orcid.org/0000-0002-9837-6000"},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mahnaz Maddah","raw_affiliation_strings":["Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Data Sciences Platform, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020290782","display_name":"Daniel E. Singer","orcid":"https://orcid.org/0000-0001-6145-4848"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel E. Singer","raw_affiliation_strings":["Division of General Internal Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General Internal Medicine, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107931391","display_name":"Patrick T. Ellinor","orcid":null},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1285119806","display_name":"Heart Rhythm Society","ror":"https://ror.org/035m9ft70","country_code":"US","type":"other","lineage":["https://openalex.org/I1285119806"]},{"id":"https://openalex.org/I48633490","display_name":"Mass General Brigham","ror":"https://ror.org/04py2rh25","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I48633490"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick T. Ellinor","raw_affiliation_strings":["Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA. ellinor@mgh.harvard.edu","Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA. ellinor@mgh.harvard.edu","Telemachus and Irene Demoulas Family Foundation Center for Cardiac Arrhythmias, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA. ellinor@mgh.harvard.edu","Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","Telemachus and Irene Demoulas Family Foundation Center for Cardiac Arrhythmias, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA. ellinor@mgh.harvard.edu","institution_ids":["https://openalex.org/I107606265"]},{"raw_affiliation_string":"Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA. ellinor@mgh.harvard.edu","institution_ids":["https://openalex.org/I48633490"]},{"raw_affiliation_string":"Telemachus and Irene Demoulas Family Foundation Center for Cardiac Arrhythmias, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA. ellinor@mgh.harvard.edu","institution_ids":["https://openalex.org/I1285119806"]},{"raw_affiliation_string":"Cardiovascular Disease Initiative, Broad Institute of Harvard and the Massachusetts Institute of Technology, Cambridge, MA, USA","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I63966007"]},{"raw_affiliation_string":"Telemachus and Irene Demoulas Family Foundation Center for Cardiac Arrhythmias, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I1285119806"]},{"raw_affiliation_string":"Cardiovascular Research Center, Heart and Vascular Institute, Mass General Brigham, Boston, MA, USA","institution_ids":["https://openalex.org/I48633490"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5041028758"],"corresponding_institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1285119806","https://openalex.org/I48633490","https://openalex.org/I63966007"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":4.8445,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.95884199,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"8","issue":"1","first_page":"776","last_page":"776"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11021","display_name":"ECG Monitoring and Analysis","score":0.9072999954223633,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11021","display_name":"ECG Monitoring and Analysis","score":0.9072999954223633,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10065","display_name":"Atrial Fibrillation Management and Outcomes","score":0.06239999830722809,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.005200000014156103,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/receiver-operating-characteristic","display_name":"Receiver operating characteristic","score":0.6687999963760376},{"id":"https://openalex.org/keywords/randomized-controlled-trial","display_name":"Randomized controlled trial","score":0.6044999957084656},{"id":"https://openalex.org/keywords/atrial-fibrillation","display_name":"Atrial fibrillation","score":0.3508000075817108},{"id":"https://openalex.org/keywords/primary-care","display_name":"Primary care","score":0.35040000081062317},{"id":"https://openalex.org/keywords/sample-size-determination","display_name":"Sample size determination","score":0.32260000705718994},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.31459999084472656},{"id":"https://openalex.org/keywords/electrocardiography","display_name":"Electrocardiography","score":0.3140000104904175}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8187000155448914},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.6687999963760376},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.6044999957084656},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41990000009536743},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.4133000075817108},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.3508000075817108},{"id":"https://openalex.org/C2984752397","wikidata":"https://www.wikidata.org/wiki/Q3259956","display_name":"Primary care","level":2,"score":0.35040000081062317},{"id":"https://openalex.org/C129848803","wikidata":"https://www.wikidata.org/wiki/Q2564360","display_name":"Sample size determination","level":2,"score":0.32260000705718994},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.31459999084472656},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.3140000104904175},{"id":"https://openalex.org/C198531522","wikidata":"https://www.wikidata.org/wiki/Q485146","display_name":"Sample (material)","level":2,"score":0.30090001225471497},{"id":"https://openalex.org/C186967261","wikidata":"https://www.wikidata.org/wiki/Q5082128","display_name":"Mobile device","level":2,"score":0.3003999888896942},{"id":"https://openalex.org/C76318530","wikidata":"https://www.wikidata.org/wiki/Q16833590","display_name":"Area under the curve","level":2,"score":0.29490000009536743},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.29109999537467957},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.2782999873161316},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.27799999713897705},{"id":"https://openalex.org/C3020225094","wikidata":"https://www.wikidata.org/wiki/Q80091","display_name":"Area under curve","level":3,"score":0.2655999958515167},{"id":"https://openalex.org/C2993769353","wikidata":"https://www.wikidata.org/wiki/Q7598360","display_name":"Standard of care","level":2,"score":0.26010000705718994},{"id":"https://openalex.org/C2988455589","wikidata":"https://www.wikidata.org/wiki/Q189331","display_name":"Cardiac arrhythmia","level":3,"score":0.25}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-025-02164-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-02164-2","pdf_url":"https://www.nature.com/articles/s41746-025-02164-2_reference.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:41299008","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41299008","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:10e0b7c2852d491db7f1f6db52193769","is_oa":true,"landing_page_url":"https://doaj.org/article/10e0b7c2852d491db7f1f6db52193769","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 8, Iss 1, Pp 1-12 (2025)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12722369","is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12722369/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-025-02164-2","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-02164-2","pdf_url":"https://www.nature.com/articles/s41746-025-02164-2_reference.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G102488861","display_name":null,"funder_award_id":"23CDA1050571","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1422020304","display_name":null,"funder_award_id":"MAESTRIA 965286","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G1445764998","display_name":null,"funder_award_id":"961045","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1904825286","display_name":null,"funder_award_id":"18SFRN34250007","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G1972255387","display_name":null,"funder_award_id":"R01HL139731","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4077987447","display_name":null,"funder_award_id":"18SFRN34110082","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4904173694","display_name":null,"funder_award_id":"T32HL007208","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5068758199","display_name":null,"funder_award_id":"521832260","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G5342260708","display_name":null,"funder_award_id":"R01HL092577","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5573957870","display_name":null,"funder_award_id":"R01HL157635","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5821201378","display_name":null,"funder_award_id":"K23HL169839","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6199015224","display_name":null,"funder_award_id":"K23HL169839","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6369611890","display_name":null,"funder_award_id":"18SFRN34110082","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G6967075033","display_name":null,"funder_award_id":"965286","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G7263423286","display_name":null,"funder_award_id":"R01HL092577","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7493452529","display_name":null,"funder_award_id":"T32HL007208","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7910446648","display_name":null,"funder_award_id":"965286","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G8422410150","display_name":"Electrocardiogram-based deep learning and decision analysis to improve atrial fibrillation risk estimation","funder_award_id":"23CDA1050571","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G8630864450","display_name":null,"funder_award_id":"18SFRN34250007","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8643053124","display_name":null,"funder_award_id":"965286","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8767518440","display_name":null,"funder_award_id":"MAESTRIA 965286","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G8944425447","display_name":null,"funder_award_id":"961045","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"},{"id":"https://openalex.org/G8993135685","display_name":null,"funder_award_id":"R01HL092577","funder_id":"https://openalex.org/F4320306230","funder_display_name":"American Heart Association"}],"funders":[{"id":"https://openalex.org/F4320306230","display_name":"American Heart Association","ror":"https://ror.org/013kjyp64"},{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4416691671.pdf","grobid_xml":"https://content.openalex.org/works/W4416691671.grobid-xml"},"referenced_works_count":51,"referenced_works":["https://openalex.org/W1207268963","https://openalex.org/W2045030989","https://openalex.org/W2055181085","https://openalex.org/W2097173178","https://openalex.org/W2102904190","https://openalex.org/W2106421416","https://openalex.org/W2106556258","https://openalex.org/W2112316706","https://openalex.org/W2132432664","https://openalex.org/W2152623033","https://openalex.org/W2161982707","https://openalex.org/W2162586165","https://openalex.org/W2306725801","https://openalex.org/W2395855281","https://openalex.org/W2499224120","https://openalex.org/W2809217674","https://openalex.org/W2869528658","https://openalex.org/W2911834420","https://openalex.org/W2947341597","https://openalex.org/W2949928190","https://openalex.org/W2965520043","https://openalex.org/W2978962447","https://openalex.org/W2997250629","https://openalex.org/W3020992444","https://openalex.org/W3034503810","https://openalex.org/W3035961209","https://openalex.org/W3082188176","https://openalex.org/W3098712771","https://openalex.org/W3107986792","https://openalex.org/W3112118782","https://openalex.org/W3133470659","https://openalex.org/W3196294155","https://openalex.org/W3203526032","https://openalex.org/W3212883348","https://openalex.org/W4212937040","https://openalex.org/W4221077724","https://openalex.org/W4223532457","https://openalex.org/W4283166591","https://openalex.org/W4292280632","https://openalex.org/W4310568840","https://openalex.org/W4317491755","https://openalex.org/W4378838672","https://openalex.org/W4383911793","https://openalex.org/W4386419398","https://openalex.org/W4387381237","https://openalex.org/W4387728496","https://openalex.org/W4389166035","https://openalex.org/W4389617987","https://openalex.org/W4407713188","https://openalex.org/W4409012611","https://openalex.org/W4409483458"],"related_works":[],"abstract_inverted_index":{"Whether":[0],"artificial":[1],"intelligence":[2],"(AI)":[3],"analysis":[4],"of":[5,25,61,93,160],"single-lead":[6],"ECG":[7,36,72],"(1":[8,108],"L":[9,35,75,104,109,153],"ECG)":[10],"can":[11],"predict":[12],"incident":[13,44,100],"AF":[14,45,80,98,101,161],"is":[15],"unknown.":[16],"In":[17,57,88],"the":[18,49,53,89,117],"VITAL-AF":[19,86,91],"trial":[20],"(ClinicalTrials.gov":[21],"NCT03515057,":[22],"registered":[23],"2/24/2021)":[24],"primary":[26],"care":[27],"patients":[28],"aged":[29],"\u226565":[30,149],"years":[31,150],"undergoing":[32],"handheld":[33],"1":[34,103,152],"screening,":[37],"we":[38],"tested":[39],"three":[40],"AI":[41,66],"approaches":[42],"to":[43,52,82,128],"prediction,":[46],"and":[47,158],"compared":[48],"best":[50],"model":[51,67],"CHARGE-AF":[54,129],"risk":[55],"score.":[56],"a":[58,64],"test":[59],"set":[60],"4,221":[62],"individuals,":[63],"published":[65],"trained":[68,84],"using":[69],"single":[70],"standard":[71],"leads":[73],"(\"1":[74],"ECG-AI\")":[76],"provided":[77],"similar":[78],"2-year":[79],"discrimination":[81,114],"models":[83],"with":[85,106],"data.":[87],"full":[90],"sample":[92],"15,694":[94],"individuals":[95],"without":[96],"prevalent":[97],"(2-year":[99],"3.1%),":[102],"ECG-AI":[105,110,154],"age/sex":[107],"AS)":[111],"had":[112],"comparable":[113],"(area":[115],"under":[116],"receiver":[118],"operating":[119],"characteristic":[120],"curve":[121],"[AUROC]":[122],"0.695[0.637-0.742];":[123],"average":[124],"precision":[125],"[AP]":[126],"0.060[0.050-0.078])":[127],"(AUROC":[130],"0.679[0.623-0.730];":[131],"AP":[132,138],"0.062[0.052-0.080],":[133],"AUROC":[134],"p":[135,139],"=":[136,140],"0.46,":[137],"0.92).":[141],"Net":[142],"reclassification":[143],"improvement":[144],"was":[145],"favorable":[146],"versus":[147],"age":[148],"(0.27[0.22-0.32]).":[151],"may":[155],"increase":[156],"efficiency":[157],"reach":[159],"screening.":[162]},"counts_by_year":[{"year":2026,"cited_by_count":4}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-11-27T00:00:00"}