{"id":"https://openalex.org/W4415988375","doi":"https://doi.org/10.1038/s41746-025-02035-w","title":"A generalizable 3D framework and model for self-supervised learning in medical imaging","display_name":"A generalizable 3D framework and model for self-supervised learning in medical imaging","publication_year":2025,"publication_date":"2025-11-07","ids":{"openalex":"https://openalex.org/W4415988375","doi":"https://doi.org/10.1038/s41746-025-02035-w","pmid":"https://pubmed.ncbi.nlm.nih.gov/41203891"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-025-02035-w","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-02035-w","pdf_url":"https://www.nature.com/articles/s41746-025-02035-w.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-025-02035-w.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044805857","display_name":"Tony Xu","orcid":"https://orcid.org/0000-0002-9825-1005"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Tony Xu","raw_affiliation_strings":["Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016689213","display_name":"Sepehr Hosseini","orcid":null},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Sepehr Hosseini","raw_affiliation_strings":["Department of Computer Science, University of Toronto, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103476816","display_name":"Chris Anderson","orcid":null},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Chris Anderson","raw_affiliation_strings":["Institute for Aerospace Studies, University of Toronto, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Aerospace Studies, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052573996","display_name":"Anthony Rinaldi","orcid":"https://orcid.org/0000-0003-3686-7485"},"institutions":[{"id":"https://openalex.org/I1323843004","display_name":"Sunnybrook Health Science Centre","ror":"https://ror.org/03wefcv03","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004"]},{"id":"https://openalex.org/I4391768120","display_name":"Sunnybrook Research Institute","ror":"https://ror.org/05n0tzs53","country_code":null,"type":"facility","lineage":["https://openalex.org/I1323843004","https://openalex.org/I185261750","https://openalex.org/I4391768120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Anthony Rinaldi","raw_affiliation_strings":["Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada","institution_ids":["https://openalex.org/I1323843004","https://openalex.org/I4391768120"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073514348","display_name":"Rahul G. Krishnan","orcid":"https://orcid.org/0000-0002-7955-3956"},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4210127509","display_name":"Vector Institute","ror":"https://ror.org/03kqdja62","country_code":"CA","type":"facility","lineage":["https://openalex.org/I4210127509"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Rahul G. Krishnan","raw_affiliation_strings":["Department of Computer Science, University of Toronto, Toronto, ON, Canada","Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada","Vector Institute, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Science, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Vector Institute, Toronto, ON, Canada","institution_ids":["https://openalex.org/I4210127509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029260213","display_name":"Anne L. Martel","orcid":"https://orcid.org/0000-0003-1375-5501"},"institutions":[{"id":"https://openalex.org/I1323843004","display_name":"Sunnybrook Health Science Centre","ror":"https://ror.org/03wefcv03","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I4391768120","display_name":"Sunnybrook Research Institute","ror":"https://ror.org/05n0tzs53","country_code":null,"type":"facility","lineage":["https://openalex.org/I1323843004","https://openalex.org/I185261750","https://openalex.org/I4391768120"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Anne L. Martel","raw_affiliation_strings":["Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada","Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada","institution_ids":["https://openalex.org/I1323843004","https://openalex.org/I4391768120"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056005902","display_name":"Maged Goubran","orcid":"https://orcid.org/0000-0001-5880-0818"},"institutions":[{"id":"https://openalex.org/I1323843004","display_name":"Sunnybrook Health Science Centre","ror":"https://ror.org/03wefcv03","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I1323843004"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2802362269","display_name":"Health Sciences Centre","ror":"https://ror.org/05pr37258","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I110535807","https://openalex.org/I2802362269"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Maged Goubran","raw_affiliation_strings":["Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. maged.goubran@utoronto.ca","Harquail Centre for Neuromodulation, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. maged.goubran@utoronto.ca","Hurvitz Brain Sciences, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. maged.goubran@utoronto.ca","Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada. maged.goubran@utoronto.ca","Harquail Centre for Neuromodulation, Sunnybrook Health Sciences Centre, Toronto, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada. maged.goubran@utoronto.ca","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Harquail Centre for Neuromodulation, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. maged.goubran@utoronto.ca","institution_ids":["https://openalex.org/I1323843004"]},{"raw_affiliation_string":"Hurvitz Brain Sciences, Sunnybrook Health Sciences Centre, Toronto, ON, Canada. maged.goubran@utoronto.ca","institution_ids":["https://openalex.org/I1323843004"]},{"raw_affiliation_string":"Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada. maged.goubran@utoronto.ca","institution_ids":["https://openalex.org/I1323843004"]},{"raw_affiliation_string":"Harquail Centre for Neuromodulation, Sunnybrook Health Sciences Centre, Toronto, ON, Canada","institution_ids":["https://openalex.org/I1323843004","https://openalex.org/I2802362269"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5056005902"],"corresponding_institution_ids":["https://openalex.org/I1323843004","https://openalex.org/I185261750","https://openalex.org/I2802362269"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":18.5127,"has_fulltext":true,"cited_by_count":13,"citation_normalized_percentile":{"value":0.99183885,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":100},"biblio":{"volume":"8","issue":"1","first_page":"639","last_page":"639"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11307","display_name":"Domain Adaptation and Few-Shot Learning","score":0.6922000050544739,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11307","display_name":"Domain Adaptation and Few-Shot Learning","score":0.6922000050544739,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10036","display_name":"Advanced Neural Network Applications","score":0.05040000006556511,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10719","display_name":"3D Shape Modeling and Analysis","score":0.027000000700354576,"subfield":{"id":"https://openalex.org/subfields/2206","display_name":"Computational Mechanics"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/generalizability-theory","display_name":"Generalizability theory","score":0.7110000252723694},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.6782000064849854},{"id":"https://openalex.org/keywords/limiting","display_name":"Limiting","score":0.4375999867916107},{"id":"https://openalex.org/keywords/pretext","display_name":"Pretext","score":0.4316999912261963},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.3767000138759613},{"id":"https://openalex.org/keywords/medical-diagnosis","display_name":"Medical diagnosis","score":0.37529999017715454}],"concepts":[{"id":"https://openalex.org/C27158222","wikidata":"https://www.wikidata.org/wiki/Q5532422","display_name":"Generalizability theory","level":2,"score":0.7110000252723694},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.6782000064849854},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6089000105857849},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5365999937057495},{"id":"https://openalex.org/C188198153","wikidata":"https://www.wikidata.org/wiki/Q1613840","display_name":"Limiting","level":2,"score":0.4375999867916107},{"id":"https://openalex.org/C2779627259","wikidata":"https://www.wikidata.org/wiki/Q779763","display_name":"Pretext","level":3,"score":0.4316999912261963},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.3767000138759613},{"id":"https://openalex.org/C534262118","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Medical diagnosis","level":2,"score":0.37529999017715454},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.365200012922287},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.32170000672340393},{"id":"https://openalex.org/C108583219","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep learning","level":2,"score":0.3077000081539154},{"id":"https://openalex.org/C2780586882","wikidata":"https://www.wikidata.org/wiki/Q7520643","display_name":"Simple (philosophy)","level":2,"score":0.30250000953674316},{"id":"https://openalex.org/C26517878","wikidata":"https://www.wikidata.org/wiki/Q228039","display_name":"Key (lock)","level":2,"score":0.27950000762939453},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.2653999924659729},{"id":"https://openalex.org/C2780910867","wikidata":"https://www.wikidata.org/wiki/Q1952416","display_name":"Multimodality","level":2,"score":0.2572999894618988}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-025-02035-w","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-02035-w","pdf_url":"https://www.nature.com/articles/s41746-025-02035-w.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:41203891","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/41203891","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:46587fd3b0174bbbbb7d121ec5d8f40b","is_oa":true,"landing_page_url":"https://doaj.org/article/46587fd3b0174bbbbb7d121ec5d8f40b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 8, Iss 1, Pp 1-13 (2025)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:11403795","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12594808","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-025-02035-w","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-02035-w","pdf_url":"https://www.nature.com/articles/s41746-025-02035-w.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1336222015","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1658616865","display_name":null,"funder_award_id":"1U54MH091657","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1880935189","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320327918","funder_display_name":"H. Lundbeck A/S"},{"id":"https://openalex.org/G2452851128","display_name":null,"funder_award_id":"R01 AG043434","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G2874164972","display_name":null,"funder_award_id":"1U54MH091657","funder_id":"https://openalex.org/F4320334593","funder_display_name":"Natural Sciences and Engineering Research Council of Canada"},{"id":"https://openalex.org/G29951154","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320309697","funder_display_name":"Alzheimer's Disease Neuroimaging Initiative"},{"id":"https://openalex.org/G3553156159","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320307115","funder_display_name":"Bristol-Myers Squibb"},{"id":"https://openalex.org/G3649828873","display_name":null,"funder_award_id":"R01 EB009352","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G3752451908","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320327235","funder_display_name":"Servier"},{"id":"https://openalex.org/G3870774570","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320332193","funder_display_name":"Genentech"},{"id":"https://openalex.org/G3889924253","display_name":null,"funder_award_id":"U54 MH091657","funder_id":"https://openalex.org/F4320337346","funder_display_name":"National Institute of Mental Health"},{"id":"https://openalex.org/G4079001475","display_name":null,"funder_award_id":"U19 AG024904","funder_id":"https://openalex.org/F4320309697","funder_display_name":"Alzheimer's Disease Neuroimaging Initiative"},{"id":"https://openalex.org/G4184131626","display_name":null,"funder_award_id":"CRC-2021-00374","funder_id":"https://openalex.org/F4320320994","funder_display_name":"Canada Research Chairs"},{"id":"https://openalex.org/G4423162591","display_name":null,"funder_award_id":"UL1 TR000448","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G4501223628","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320329118","funder_display_name":"IXICO"},{"id":"https://openalex.org/G5209990037","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320307765","funder_display_name":"Pfizer"},{"id":"https://openalex.org/G5235017436","display_name":null,"funder_award_id":"U19 AG024904","funder_id":"https://openalex.org/F4320306080","funder_display_name":"Foundation for the National Institutes of Health"},{"id":"https://openalex.org/G5654639750","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320310045","funder_display_name":"BioClinica"},{"id":"https://openalex.org/G5740349702","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320309470","funder_display_name":"Meso Scale Diagnostics"},{"id":"https://openalex.org/G6125213735","display_name":null,"funder_award_id":"P01 AG026276","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6371410416","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320308604","funder_display_name":"Biogen"},{"id":"https://openalex.org/G6408348050","display_name":null,"funder_award_id":"02035","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6533576634","display_name":null,"funder_award_id":"U19 AG024904","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6786645331","display_name":null,"funder_award_id":"P01 AG003991","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6847837052","display_name":null,"funder_award_id":"P30 AG066444","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6899163935","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320322148","funder_display_name":"Eisai"},{"id":"https://openalex.org/G7019074589","display_name":null,"funder_award_id":"U19 AG024904","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7414321945","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320306080","funder_display_name":"Foundation for the National Institutes of Health"},{"id":"https://openalex.org/G781725486","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320307758","funder_display_name":"Eli Lilly and Company"},{"id":"https://openalex.org/G8299918676","display_name":null,"funder_award_id":"1U54MH091657","funder_id":"https://openalex.org/F4320332884","funder_display_name":"McDonnell Center for Systems Neuroscience"},{"id":"https://openalex.org/G839208290","display_name":null,"funder_award_id":"AG024904","funder_id":"https://openalex.org/F4320310388","funder_display_name":"Novartis Pharmaceuticals Corporation"},{"id":"https://openalex.org/G851769110","display_name":null,"funder_award_id":"1U54MH091657","funder_id":"https://openalex.org/F4320306080","funder_display_name":"Foundation for the National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306080","display_name":"Foundation for the National Institutes of Health","ror":"https://ror.org/00k86s890"},{"id":"https://openalex.org/F4320306219","display_name":"Alzheimer's Association","ror":"https://ror.org/0375f4d26"},{"id":"https://openalex.org/F4320307115","display_name":"Bristol-Myers Squibb","ror":"https://ror.org/00gtmwv55"},{"id":"https://openalex.org/F4320307758","display_name":"Eli Lilly and Company","ror":"https://ror.org/01qat3289"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320308604","display_name":"Biogen","ror":"https://ror.org/02jqkb192"},{"id":"https://openalex.org/F4320309470","display_name":"Meso Scale Diagnostics","ror":"https://ror.org/05jgy0m16"},{"id":"https://openalex.org/F4320309697","display_name":"Alzheimer's Disease Neuroimaging Initiative","ror":"https://ror.org/01j20wc74"},{"id":"https://openalex.org/F4320310045","display_name":"BioClinica","ror":"https://ror.org/03t95yr58"},{"id":"https://openalex.org/F4320310388","display_name":"Novartis Pharmaceuticals Corporation","ror":"https://ror.org/028fhxy95"},{"id":"https://openalex.org/F4320310630","display_name":"University of Ottawa","ror":"https://ror.org/03c4mmv16"},{"id":"https://openalex.org/F4320311526","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29"},{"id":"https://openalex.org/F4320311551","display_name":"Northern California Institute for Research and Education","ror":"https://ror.org/05p48p517"},{"id":"https://openalex.org/F4320314607","display_name":"Government of Ontario","ror":"https://ror.org/015pzp858"},{"id":"https://openalex.org/F4320315043","display_name":"Centre for Addiction and Mental Health Foundation","ror":null},{"id":"https://openalex.org/F4320319206","display_name":"London Health Sciences Foundation","ror":null},{"id":"https://openalex.org/F4320320994","display_name":"Canada Research Chairs","ror":"https://ror.org/0517h6h17"},{"id":"https://openalex.org/F4320321832","display_name":"Queen's University","ror":"https://ror.org/02y72wh86"},{"id":"https://openalex.org/F4320322148","display_name":"Eisai","ror":"https://ror.org/04vvh7p27"},{"id":"https://openalex.org/F4320327235","display_name":"Servier","ror":"https://ror.org/034e7c066"},{"id":"https://openalex.org/F4320327918","display_name":"H. Lundbeck A/S","ror":null},{"id":"https://openalex.org/F4320329118","display_name":"IXICO","ror":"https://ror.org/00paezp73"},{"id":"https://openalex.org/F4320329765","display_name":"Temerty Family Foundation","ror":null},{"id":"https://openalex.org/F4320331257","display_name":"Alliance de recherche num\u00e9rique du Canada","ror":"https://ror.org/010r6td27"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332193","display_name":"Genentech","ror":"https://ror.org/04gndp242"},{"id":"https://openalex.org/F4320332502","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60"},{"id":"https://openalex.org/F4320332884","display_name":"McDonnell Center for Systems Neuroscience","ror":"https://ror.org/01yc7t268"},{"id":"https://openalex.org/F4320334506","display_name":"Canadian Institutes of Health Research","ror":"https://ror.org/01gavpb45"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"},{"id":"https://openalex.org/F4320335109","display_name":"Faculty of Health Sciences, Queen's University","ror":"https://ror.org/02y72wh86"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337346","display_name":"National Institute of Mental Health","ror":"https://ror.org/04xeg9z08"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F747265653","display_name":"Google Research","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4415988375.pdf","grobid_xml":"https://content.openalex.org/works/W4415988375.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1213336605","https://openalex.org/W1901129140","https://openalex.org/W2083927153","https://openalex.org/W2143895814","https://openalex.org/W2563619737","https://openalex.org/W2886281300","https://openalex.org/W2952378269","https://openalex.org/W3007943565","https://openalex.org/W3024107846","https://openalex.org/W3025885500","https://openalex.org/W3033492597","https://openalex.org/W3093394156","https://openalex.org/W3112217930","https://openalex.org/W3126165211","https://openalex.org/W3128830162","https://openalex.org/W3137048919","https://openalex.org/W3137540880","https://openalex.org/W3138516171","https://openalex.org/W3138985726","https://openalex.org/W3139349917","https://openalex.org/W3159019058","https://openalex.org/W3159481202","https://openalex.org/W3161335554","https://openalex.org/W3165693204","https://openalex.org/W3194943434","https://openalex.org/W3197417533","https://openalex.org/W3205076722","https://openalex.org/W4212875960","https://openalex.org/W4283772197","https://openalex.org/W4312200733","https://openalex.org/W4312428231","https://openalex.org/W4313156423","https://openalex.org/W4318833700","https://openalex.org/W4319300504","https://openalex.org/W4385190584","https://openalex.org/W4390874575","https://openalex.org/W4410838785","https://openalex.org/W6902877415","https://openalex.org/W6902994697","https://openalex.org/W6940641214","https://openalex.org/W6977648119"],"related_works":[],"abstract_inverted_index":{"Current":[0],"self-supervised":[1],"learning":[2],"(SSL)":[3],"methods":[4],"for":[5,41],"3D":[6,33,51],"medical":[7,42],"imaging":[8,67],"rely":[9],"on":[10,44,64],"simple":[11],"pretext":[12],"formulations":[13],"and":[14,22,35],"organ-":[15],"or":[16],"modality-specific":[17],"datasets,":[18,34],"limiting":[19],"their":[20],"generalizability":[21],"scalability.":[23],"We":[24,57],"present":[25],"3DINO,":[26],"a":[27,38,45],"cutting-edge":[28],"SSL":[29],"method":[30],"adapted":[31],"to":[32],"pretrain":[36],"3DINO-ViT:":[37],"general-purpose":[39],"model":[40],"imaging,":[43],"ultra-large":[46],"multimodal":[47],"dataset":[48],"of":[49],"~100,000":[50],"scans":[52],"from":[53],"over":[54],"10":[55],"organs.":[56],"show":[58],"3DINO-ViT":[59],"outperforms":[60],"state-of-the-art":[61],"pretrained":[62],"models":[63],"numerous":[65],"downstream":[66],"tasks.":[68]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":1}],"updated_date":"2026-07-08T08:33:18.762332","created_date":"2025-11-07T00:00:00"}