{"id":"https://openalex.org/W4410707193","doi":"https://doi.org/10.1038/s41746-025-01723-x","title":"Enhanced staging of renal cell carcinoma using tumor morphology features: model development and multi-source validation","display_name":"Enhanced staging of renal cell carcinoma using tumor morphology features: model development and multi-source validation","publication_year":2025,"publication_date":"2025-05-24","ids":{"openalex":"https://openalex.org/W4410707193","doi":"https://doi.org/10.1038/s41746-025-01723-x","pmid":"https://pubmed.ncbi.nlm.nih.gov/40413285"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-025-01723-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01723-x","pdf_url":"https://www.nature.com/articles/s41746-025-01723-x.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-025-01723-x.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012972036","display_name":"Enyu Yuan","orcid":"https://orcid.org/0000-0002-5387-1729"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Enyu Yuan","raw_affiliation_strings":["Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5119103153","display_name":"Yuntian Chen","orcid":"https://orcid.org/0000-0001-8248-312X"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuntian Chen","raw_affiliation_strings":["Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100328602","display_name":"Lei Ye","orcid":null},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Ye","raw_affiliation_strings":["Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102823882","display_name":"Ben He","orcid":"https://orcid.org/0000-0003-4524-225X"},"institutions":[{"id":"https://openalex.org/I4210093384","display_name":"Third People's Hospital of Chengdu","ror":"https://ror.org/00ebdgr24","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093384"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ben He","raw_affiliation_strings":["Department of Urology, The Third People's Hospital of Chengdu/The Affiliated Hospital of Southwest Jiaotong University, Chengdu, 610014, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, The Third People's Hospital of Chengdu/The Affiliated Hospital of Southwest Jiaotong University, Chengdu, 610014, China","institution_ids":["https://openalex.org/I4210093384"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103416343","display_name":"Chunlei He","orcid":"https://orcid.org/0009-0002-2319-0604"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4210134288","display_name":"Sanya Central Hospital","ror":"https://ror.org/03t65z939","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134288"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"ChunLei He","raw_affiliation_strings":["Department of Radiology, Sanya People's Hospital, Sanya, China","Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Sanya People's Hospital, Sanya, China","institution_ids":["https://openalex.org/I4210134288"]},{"raw_affiliation_string":"Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038675945","display_name":"Junchao Ma","orcid":"https://orcid.org/0000-0001-8397-086X"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Junchao Ma","raw_affiliation_strings":["Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102729938","display_name":"Ting Yang","orcid":"https://orcid.org/0000-0002-7835-3899"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ting Yang","raw_affiliation_strings":["Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026006324","display_name":"Hao Zeng","orcid":"https://orcid.org/0000-0002-9944-313X"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hao Zeng","raw_affiliation_strings":["Department of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, West China Hospital, Sichuan University, Chengdu, 610041, China","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101516625","display_name":"Ling Yang","orcid":"https://orcid.org/0000-0001-5674-7347"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ling Yang","raw_affiliation_strings":["Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China. florialinda@163.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China. florialinda@163.com","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113772295","display_name":"Jin Yao","orcid":"https://orcid.org/0009-0003-5414-6427"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jin Yao","raw_affiliation_strings":["Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China. yaojin@wchscu.edu.cn"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China. yaojin@wchscu.edu.cn","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077957037","display_name":"Bin Song","orcid":"https://orcid.org/0000-0002-7269-2101"},"institutions":[{"id":"https://openalex.org/I24185976","display_name":"Sichuan University","ror":"https://ror.org/011ashp19","country_code":"CN","type":"education","lineage":["https://openalex.org/I24185976"]},{"id":"https://openalex.org/I4210089761","display_name":"West China Hospital of Sichuan University","ror":"https://ror.org/007mrxy13","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210089761"]},{"id":"https://openalex.org/I4210134288","display_name":"Sanya Central Hospital","ror":"https://ror.org/03t65z939","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210134288"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bin Song","raw_affiliation_strings":["Department of Radiology, Sanya People's Hospital, Sanya, China. songlab_radiology@163.com","Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China. songlab_radiology@163.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Sanya People's Hospital, Sanya, China. songlab_radiology@163.com","institution_ids":["https://openalex.org/I4210134288"]},{"raw_affiliation_string":"Department of Radiology, West China Hospital, Sichuan University, Chengdu, 610041, China. songlab_radiology@163.com","institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5077957037","https://openalex.org/A5101516625","https://openalex.org/A5113772295"],"corresponding_institution_ids":["https://openalex.org/I24185976","https://openalex.org/I4210089761","https://openalex.org/I4210134288"],"apc_list":{"value":3590,"currency":"USD","value_usd":3590},"apc_paid":{"value":3590,"currency":"USD","value_usd":3590},"fwci":2.8105,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.90545368,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"8","issue":"1","first_page":"305","last_page":"305"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12386","display_name":"Advanced X-ray and CT Imaging","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/morphology","display_name":"Morphology (biology)","score":0.6263042688369751},{"id":"https://openalex.org/keywords/renal-cell-carcinoma","display_name":"Renal cell carcinoma","score":0.5862448215484619},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.3569469451904297},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.33334678411483765},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.24571123719215393},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.20167654752731323},{"id":"https://openalex.org/keywords/zoology","display_name":"Zoology","score":0.054605692625045776}],"concepts":[{"id":"https://openalex.org/C499950583","wikidata":"https://www.wikidata.org/wiki/Q183252","display_name":"Morphology (biology)","level":2,"score":0.6263042688369751},{"id":"https://openalex.org/C2777472916","wikidata":"https://www.wikidata.org/wiki/Q1164529","display_name":"Renal cell carcinoma","level":2,"score":0.5862448215484619},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3569469451904297},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33334678411483765},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24571123719215393},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20167654752731323},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.054605692625045776}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-025-01723-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01723-x","pdf_url":"https://www.nature.com/articles/s41746-025-01723-x.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:40413285","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40413285","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:b1e9fb161c8d412ca189a0a9e36fd80d","is_oa":true,"landing_page_url":"https://doaj.org/article/b1e9fb161c8d412ca189a0a9e36fd80d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 8, Iss 1, Pp 1-10 (2025)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12103548","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12103548","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-025-01723-x","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01723-x","pdf_url":"https://www.nature.com/articles/s41746-025-01723-x.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.6000000238418579}],"awards":[{"id":"https://openalex.org/G1477959158","display_name":null,"funder_award_id":"ZYAI24048","funder_id":"https://openalex.org/F4320322990","funder_display_name":"Sichuan University"},{"id":"https://openalex.org/G7899741169","display_name":null,"funder_award_id":"1.3.5","funder_id":"https://openalex.org/F4320336042","funder_display_name":"West China Hospital, Sichuan University"}],"funders":[{"id":"https://openalex.org/F4320322990","display_name":"Sichuan University","ror":"https://ror.org/011ashp19"},{"id":"https://openalex.org/F4320336042","display_name":"West China Hospital, Sichuan University","ror":"https://ror.org/007mrxy13"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410707193.pdf","grobid_xml":"https://content.openalex.org/works/W4410707193.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W155107627","https://openalex.org/W2011531785","https://openalex.org/W2026521067","https://openalex.org/W2026616100","https://openalex.org/W2050710943","https://openalex.org/W2060571247","https://openalex.org/W2076926923","https://openalex.org/W2084413241","https://openalex.org/W2102150307","https://openalex.org/W2105572353","https://openalex.org/W2119663496","https://openalex.org/W2127890285","https://openalex.org/W2137364132","https://openalex.org/W2159102520","https://openalex.org/W2328176404","https://openalex.org/W2604162265","https://openalex.org/W2892325025","https://openalex.org/W2980145319","https://openalex.org/W2998789541","https://openalex.org/W3007668496","https://openalex.org/W3012406014","https://openalex.org/W3137421095","https://openalex.org/W3154623945","https://openalex.org/W3165326067","https://openalex.org/W3212398994","https://openalex.org/W4220685687","https://openalex.org/W4286215452","https://openalex.org/W4293179620","https://openalex.org/W4313255244","https://openalex.org/W4315648877","https://openalex.org/W4368342591","https://openalex.org/W4377989430","https://openalex.org/W4385337619","https://openalex.org/W4385808837","https://openalex.org/W4392602935","https://openalex.org/W4400519786","https://openalex.org/W6675354045","https://openalex.org/W6921545207","https://openalex.org/W6940237106","https://openalex.org/W6978342796","https://openalex.org/W6978407276"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Preoperative":[0],"detection":[1],"of":[2],"pT3a":[3,27,133],"invasion":[4,134],"in":[5,87,146],"non-metastatic":[6],"renal":[7],"cell":[8],"carcinoma":[9],"(RCC)":[10],"remains":[11],"challenging":[12],"with":[13,64],"CT.":[14],"This":[15,119],"study":[16,63,120],"developed":[17],"and":[18,33,53,84,93,107,135],"validated":[19,35],"radiomic":[20,124],"models":[21,30],"using":[22],"preoperative":[23,147],"CT":[24],"to":[25],"identify":[26],"invasions.":[28],"Six":[29],"were":[31],"trained":[32],"internally":[34],"via":[36],"nested":[37],"cross-validation":[38],"on":[39],"999":[40],"patients":[41,49,55],"from":[42,50,56],"one":[43],"hospital.":[44],"External":[45],"validation":[46],"included":[47],"313":[48],"two":[51],"hospitals":[52],"204":[54],"four":[57],"TCIA":[58],"datasets.":[59],"A":[60],"multi-reader":[61],"multi-case":[62],"seven":[65],"radiologists":[66],"evaluated":[67],"the":[68,76,127],"model's":[69],"incremental":[70],"value.":[71],"The":[72],"morphology":[73,128],"model":[74],"achieved":[75],"highest":[77],"internal":[78],"AUC":[79],"(0.867,":[80],"95%":[81],"CI:":[82],"0.866-0.869)":[83],"maintained":[85],"performance":[86],"external":[88],"validations":[89],"(AUC":[90],"=":[91],"0.895":[92],"0.842).":[94],"When":[95],"used":[96],"as":[97],"a":[98],"second":[99],"reader,":[100],"it":[101],"significantly":[102],"improved":[103],"junior":[104,140],"radiologists'":[105],"sensitivity":[106],"discrimination":[108],"(AUC:":[109],"0.790":[110],"vs.":[111],"0.831,":[112],"p":[113],"<":[114],"0.001)":[115],"without":[116],"compromising":[117],"specificity.":[118],"demonstrates":[121],"that":[122],"CT-based":[123],"models,":[125],"particularly":[126],"model,":[129],"can":[130],"reliably":[131],"detect":[132],"enhance":[136],"diagnostic":[137],"accuracy":[138],"for":[139],"radiologists,":[141],"offering":[142],"potential":[143],"clinical":[144],"utility":[145],"staging.":[148]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}
