{"id":"https://openalex.org/W4410629193","doi":"https://doi.org/10.1038/s41746-025-01712-0","title":"Multimodal fusion model for prognostic prediction and radiotherapy response assessment in head and neck squamous cell carcinoma","display_name":"Multimodal fusion model for prognostic prediction and radiotherapy response assessment in head and neck squamous cell carcinoma","publication_year":2025,"publication_date":"2025-05-23","ids":{"openalex":"https://openalex.org/W4410629193","doi":"https://doi.org/10.1038/s41746-025-01712-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/40410262"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-025-01712-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01712-0","pdf_url":"https://www.nature.com/articles/s41746-025-01712-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-025-01712-0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068710758","display_name":"Ruxian Tian","orcid":null},"institutions":[{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]},{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ruxian Tian","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014366544","display_name":"Fengsu Hou","orcid":"https://orcid.org/0000-0001-5869-4365"},"institutions":[{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]},{"id":"https://openalex.org/I4210116869","display_name":"Affiliated Hospital of Qingdao University","ror":"https://ror.org/026e9yy16","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210116869"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Feng Hou","raw_affiliation_strings":["Department of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, Affiliated Hospital of Qingdao University, Qingdao, China","institution_ids":["https://openalex.org/I108688024","https://openalex.org/I4210116869"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037386810","display_name":"Haicheng Zhang","orcid":"https://orcid.org/0000-0002-5357-6332"},"institutions":[{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haicheng Zhang","raw_affiliation_strings":["Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an, China","institution_ids":["https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058340142","display_name":"Guohua Yu","orcid":"https://orcid.org/0000-0002-3260-3178"},"institutions":[{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]},{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guohua Yu","raw_affiliation_strings":["Department of Pathology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100681639","display_name":"Ping Yang","orcid":"https://orcid.org/0000-0003-2904-8916"},"institutions":[{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]},{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ping Yang","raw_affiliation_strings":["Department of Pathology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060192502","display_name":"J. Li","orcid":"https://orcid.org/0009-0004-9955-3576"},"institutions":[{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]},{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiaxuan Li","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009144350","display_name":"Ting Yuan","orcid":"https://orcid.org/0000-0002-9895-1677"},"institutions":[{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]},{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ting Yuan","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100330047","display_name":"Xi Chen","orcid":"https://orcid.org/0000-0003-3843-6478"},"institutions":[{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]},{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xi Chen","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028651392","display_name":"Y.-Z. Chen","orcid":null},"institutions":[{"id":"https://openalex.org/I151013683","display_name":"Binzhou University","ror":"https://ror.org/05frpfj73","country_code":"CN","type":"education","lineage":["https://openalex.org/I151013683"]},{"id":"https://openalex.org/I134841294","display_name":"Binzhou Medical University","ror":"https://ror.org/008w1vb37","country_code":"CN","type":"education","lineage":["https://openalex.org/I134841294"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Chen","raw_affiliation_strings":["The Second School of Clinical Medicine of Binzhou Medical University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"The Second School of Clinical Medicine of Binzhou Medical University, Yantai, China","institution_ids":["https://openalex.org/I151013683","https://openalex.org/I134841294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101657315","display_name":"Yan Hao","orcid":"https://orcid.org/0000-0002-1868-3087"},"institutions":[{"id":"https://openalex.org/I134738993","display_name":"Shandong University of Traditional Chinese Medicine","ror":"https://ror.org/0523y5c19","country_code":"CN","type":"education","lineage":["https://openalex.org/I134738993"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Hao","raw_affiliation_strings":["Shandong University of Traditional Chinese Medicine, Jinan, China"],"affiliations":[{"raw_affiliation_string":"Shandong University of Traditional Chinese Medicine, Jinan, China","institution_ids":["https://openalex.org/I134738993"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020298827","display_name":"Yisong Yao","orcid":"https://orcid.org/0009-0000-7593-6979"},"institutions":[{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]},{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yisong Yao","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102226960","display_name":"Hongfei Zhao","orcid":"https://orcid.org/0000-0001-9691-519X"},"institutions":[{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]},{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongfei Zhao","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022606288","display_name":"Pengyi Yu","orcid":null},"institutions":[{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]},{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pengyi Yu","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101774761","display_name":"Fang Han","orcid":"https://orcid.org/0000-0003-4130-3625"},"institutions":[{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]},{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Han Fang","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111258953","display_name":"Liling Song","orcid":null},"institutions":[{"id":"https://openalex.org/I151013683","display_name":"Binzhou University","ror":"https://ror.org/05frpfj73","country_code":"CN","type":"education","lineage":["https://openalex.org/I151013683"]},{"id":"https://openalex.org/I134841294","display_name":"Binzhou Medical University","ror":"https://ror.org/008w1vb37","country_code":"CN","type":"education","lineage":["https://openalex.org/I134841294"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liling Song","raw_affiliation_strings":["The Second School of Clinical Medicine of Binzhou Medical University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"The Second School of Clinical Medicine of Binzhou Medical University, Yantai, China","institution_ids":["https://openalex.org/I151013683","https://openalex.org/I134841294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051319405","display_name":"Anning Li","orcid":"https://orcid.org/0000-0001-6683-943X"},"institutions":[{"id":"https://openalex.org/I4210161528","display_name":"Qilu Hospital of Shandong University","ror":"https://ror.org/056ef9489","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161528"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Anning Li","raw_affiliation_strings":["Department of Radiology, Qilu Hospital of Shandong University, Jinan, China"],"affiliations":[{"raw_affiliation_string":"Department of Radiology, Qilu Hospital of Shandong University, Jinan, China","institution_ids":["https://openalex.org/I4210161528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074739329","display_name":"Zhonglu Liu","orcid":"https://orcid.org/0000-0001-7250-7968"},"institutions":[{"id":"https://openalex.org/I3018397418","display_name":"Yuhuangding Hospital","ror":"https://ror.org/05vawe413","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I3018397418"]},{"id":"https://openalex.org/I108688024","display_name":"Qingdao University","ror":"https://ror.org/021cj6z65","country_code":"CN","type":"education","lineage":["https://openalex.org/I108688024"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhonglu Liu","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China"],"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China","institution_ids":["https://openalex.org/I3018397418","https://openalex.org/I108688024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083808052","display_name":"Huaiqing Lv","orcid":"https://orcid.org/0009-0000-7554-4094"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huaiqing Lv","raw_affiliation_strings":["Linyi People's Hospital Affiliated to Shandong Second Medical University, Linyi, China. lvhuaiqing@126.com"],"affiliations":[{"raw_affiliation_string":"Linyi People's Hospital Affiliated to Shandong Second Medical University, Linyi, China. lvhuaiqing@126.com","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039420381","display_name":"Dexin Yu","orcid":"https://orcid.org/0000-0002-3430-4817"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dexin Yu","raw_affiliation_strings":["Department of Radiology, Qilu Hospital of Shandong University, Jinan, China. yudexin0330@sina.com"],"affiliations":[{"raw_affiliation_string":"Department of Radiology, Qilu Hospital of Shandong University, Jinan, China. yudexin0330@sina.com","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109728181","display_name":"Hongxia Cheng","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hongxia Cheng","raw_affiliation_strings":["Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China. hongxiacheng322@hotmail.com"],"affiliations":[{"raw_affiliation_string":"Department of Pathology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China. hongxiacheng322@hotmail.com","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059531436","display_name":"Ning Mao","orcid":"https://orcid.org/0000-0001-7097-5530"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ning Mao","raw_affiliation_strings":["Big Data and Artificial Intelligence Laboratory, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China. maoning@pku.edu.cn","Department of Radiology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China. maoning@pku.edu.cn"],"affiliations":[{"raw_affiliation_string":"Big Data and Artificial Intelligence Laboratory, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China. maoning@pku.edu.cn","institution_ids":[]},{"raw_affiliation_string":"Department of Radiology, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China. maoning@pku.edu.cn","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101973434","display_name":"Xicheng Song","orcid":"https://orcid.org/0000-0002-9789-1318"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Xicheng Song","raw_affiliation_strings":["Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China. drxchsong@163.com","Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases, Yantai, China. drxchsong@163.com","Shandong Provincial Key Laboratory of Neuroimmune Interaction and Regulation, Yantai, China. drxchsong@163.com","Yantai Key Laboratory of Otorhinolaryngologic Diseases, Yantai, China. drxchsong@163.com"],"affiliations":[{"raw_affiliation_string":"Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China. drxchsong@163.com","institution_ids":[]},{"raw_affiliation_string":"Shandong Provincial Clinical Research Center for Otorhinolaryngologic Diseases, Yantai, China. drxchsong@163.com","institution_ids":[]},{"raw_affiliation_string":"Shandong Provincial Key Laboratory of Neuroimmune Interaction and Regulation, Yantai, China. drxchsong@163.com","institution_ids":[]},{"raw_affiliation_string":"Yantai Key Laboratory of Otorhinolaryngologic Diseases, Yantai, China. drxchsong@163.com","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":22,"corresponding_author_ids":["https://openalex.org/A5068710758"],"corresponding_institution_ids":["https://openalex.org/I108688024","https://openalex.org/I3018397418"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":15.0583,"has_fulltext":true,"cited_by_count":12,"citation_normalized_percentile":{"value":0.99244349,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"8","issue":"1","first_page":"302","last_page":"302"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10202","display_name":"Lung Cancer Diagnosis and Treatment","score":0.9940000176429749,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9904000163078308,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/head-and-neck-squamous-cell-carcinoma","display_name":"Head and neck squamous-cell carcinoma","score":0.6630783677101135},{"id":"https://openalex.org/keywords/basal-cell","display_name":"Basal cell","score":0.5603569746017456},{"id":"https://openalex.org/keywords/radiation-therapy","display_name":"Radiation therapy","score":0.5560725927352905},{"id":"https://openalex.org/keywords/head-and-neck","display_name":"Head and neck","score":0.5494040846824646},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.5374581813812256},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.5315605998039246},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3973860740661621},{"id":"https://openalex.org/keywords/head-and-neck-cancer","display_name":"Head and neck cancer","score":0.3860552906990051},{"id":"https://openalex.org/keywords/radiology","display_name":"Radiology","score":0.3308027684688568},{"id":"https://openalex.org/keywords/surgery","display_name":"Surgery","score":0.12746143341064453}],"concepts":[{"id":"https://openalex.org/C2776833033","wikidata":"https://www.wikidata.org/wiki/Q1783924","display_name":"Head and neck squamous-cell carcinoma","level":4,"score":0.6630783677101135},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.5603569746017456},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.5560725927352905},{"id":"https://openalex.org/C3018411727","wikidata":"https://www.wikidata.org/wiki/Q3867488","display_name":"Head and neck","level":2,"score":0.5494040846824646},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5374581813812256},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5315605998039246},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3973860740661621},{"id":"https://openalex.org/C2776530083","wikidata":"https://www.wikidata.org/wiki/Q1783924","display_name":"Head and neck cancer","level":3,"score":0.3860552906990051},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3308027684688568},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.12746143341064453}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-025-01712-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01712-0","pdf_url":"https://www.nature.com/articles/s41746-025-01712-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:40410262","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40410262","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:61d4f2ff2c2d4f6d85a82db0668484b2","is_oa":true,"landing_page_url":"https://doaj.org/article/61d4f2ff2c2d4f6d85a82db0668484b2","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 8, Iss 1, Pp 1-14 (2025)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12102330","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12102330","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-025-01712-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01712-0","pdf_url":"https://www.nature.com/articles/s41746-025-01712-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.5199999809265137}],"awards":[{"id":"https://openalex.org/G1231421488","display_name":null,"funder_award_id":"under","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2087396116","display_name":null,"funder_award_id":"China","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2747547793","display_name":null,"funder_award_id":"No.ts20190991","funder_id":"https://openalex.org/F4320326189","funder_display_name":"Taishan Scholar Project of Shandong Province"},{"id":"https://openalex.org/G3317480652","display_name":null,"funder_award_id":"Science","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G391238517","display_name":null,"funder_award_id":", and","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G3999885995","display_name":null,"funder_award_id":"82371933","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4020255992","display_name":null,"funder_award_id":"Project","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4342591437","display_name":null,"funder_award_id":"tsqn202103197","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G561383505","display_name":null,"funder_award_id":"tsqn202103197","funder_id":"https://openalex.org/F4320326189","funder_display_name":"Taishan Scholar Project of Shandong Province"},{"id":"https://openalex.org/G5881942141","display_name":null,"funder_award_id":"202103","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5994120800","display_name":null,"funder_award_id":"Natural","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320326189","display_name":"Taishan Scholar Project of Shandong Province","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4410629193.pdf","grobid_xml":"https://content.openalex.org/works/W4410629193.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W2077964811","https://openalex.org/W2100294110","https://openalex.org/W2164317031","https://openalex.org/W2256501514","https://openalex.org/W2573152477","https://openalex.org/W2753434775","https://openalex.org/W2793831471","https://openalex.org/W2889646458","https://openalex.org/W2895926103","https://openalex.org/W2919115771","https://openalex.org/W2950591923","https://openalex.org/W2977899280","https://openalex.org/W3006104185","https://openalex.org/W3007100994","https://openalex.org/W3043729751","https://openalex.org/W3045639672","https://openalex.org/W3107533236","https://openalex.org/W3109885192","https://openalex.org/W3135900081","https://openalex.org/W3205594709","https://openalex.org/W3209089738","https://openalex.org/W3209900392","https://openalex.org/W4200111739","https://openalex.org/W4200146497","https://openalex.org/W4220949646","https://openalex.org/W4282935147","https://openalex.org/W4283645969","https://openalex.org/W4286217211","https://openalex.org/W4291021272","https://openalex.org/W4294051614","https://openalex.org/W4295067674","https://openalex.org/W4300960603","https://openalex.org/W4308946414","https://openalex.org/W4310639156","https://openalex.org/W4311282814","https://openalex.org/W4313493572","https://openalex.org/W4313585327","https://openalex.org/W4323860365","https://openalex.org/W4385078076","https://openalex.org/W4385460736","https://openalex.org/W4385666904","https://openalex.org/W4386247056","https://openalex.org/W4389132639","https://openalex.org/W4390262730","https://openalex.org/W4390986220","https://openalex.org/W4392543065","https://openalex.org/W4399576112"],"related_works":["https://openalex.org/W2355955825","https://openalex.org/W2056534599","https://openalex.org/W4206801305","https://openalex.org/W2382476776","https://openalex.org/W2383628288","https://openalex.org/W3210497498","https://openalex.org/W2066639416","https://openalex.org/W2147863910","https://openalex.org/W1980398461","https://openalex.org/W1991628107"],"abstract_inverted_index":{"Accurate":[0],"prediction":[1],"of":[2],"prognosis":[3,133],"and":[4,15,34,54,124,134],"postoperative":[5,74,135],"radiotherapy":[6,75,136],"response":[7],"is":[8],"critical":[9],"for":[10,142],"personalized":[11,143],"treatment":[12],"in":[13,49,57,92,116],"head":[14],"neck":[16],"squamous":[17],"cell":[18,126],"carcinoma":[19],"(HNSCC).":[20],"We":[21],"developed":[22],"a":[23,69,99,139],"multimodal":[24],"deep":[25],"learning":[26],"model":[27,110],"(MDLM)":[28],"integrating":[29],"computed":[30],"tomography,":[31],"whole-slide":[32],"images,":[33],"clinical":[35],"features":[36],"from":[37],"1087":[38],"HNSCC":[39,144],"patients":[40,97],"across":[41],"multiple":[42],"centers.":[43],"The":[44],"MDLM":[45,63,130],"exhibited":[46,76],"good":[47],"performance":[48],"predicting":[50],"overall":[51],"survival":[52,56],"(OS)":[53],"disease-free":[55],"external":[58],"test":[59],"cohorts.":[60],"Additionally,":[61],"the":[62,109,117,129],"outperformed":[64],"unimodal":[65],"models.":[66],"Patients":[67],"with":[68,98],"high-risk":[70],"score":[71,101],"who":[72,82],"underwent":[73],"prolonged":[77],"OS":[78,93],"compared":[79],"to":[80,114],"those":[81],"did":[83],"not":[84],"(P":[85,102],"=":[86,103],"0.016),":[87],"whereas":[88],"no":[89],"significant":[90],"improvement":[91],"was":[94],"observed":[95],"among":[96],"low-risk":[100],"0.898).":[104],"Biological":[105],"exploration":[106],"indicated":[107],"that":[108],"may":[111],"be":[112],"related":[113],"changes":[115],"cytochrome":[118],"P450":[119],"metabolic":[120],"pathway,":[121],"tumor":[122],"microenvironment,":[123],"myeloid-derived":[125],"subpopulations.":[127],"Overall,":[128],"effectively":[131],"predicts":[132],"response,":[137],"offering":[138],"promising":[140],"tool":[141],"therapy.":[145]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":4}],"updated_date":"2026-04-15T08:11:43.952461","created_date":"2025-10-10T00:00:00"}