{"id":"https://openalex.org/W4411221282","doi":"https://doi.org/10.1038/s41746-025-01664-5","title":"Evaluating sepsis watch generalizability through multisite external validation of a sepsis machine learning model","display_name":"Evaluating sepsis watch generalizability through multisite external validation of a sepsis machine learning model","publication_year":2025,"publication_date":"2025-06-11","ids":{"openalex":"https://openalex.org/W4411221282","doi":"https://doi.org/10.1038/s41746-025-01664-5","pmid":"https://pubmed.ncbi.nlm.nih.gov/40500319"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-025-01664-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01664-5","pdf_url":"https://www.nature.com/articles/s41746-025-01664-5.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-025-01664-5.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032190083","display_name":"Bruno Valan","orcid":"https://orcid.org/0009-0009-6588-7056"},"institutions":[{"id":"https://openalex.org/I4210124077","display_name":"Duke Institute for Health Innovation","ror":"https://ror.org/031n1rn61","country_code":"US","type":"other","lineage":["https://openalex.org/I4210124077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruno Valan","raw_affiliation_strings":["Duke Institute for Health Innovation, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke Institute for Health Innovation, Durham, NC, USA","institution_ids":["https://openalex.org/I4210124077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091337351","display_name":"Anusha Prakash","orcid":"https://orcid.org/0000-0001-7913-9336"},"institutions":[{"id":"https://openalex.org/I4210124077","display_name":"Duke Institute for Health Innovation","ror":"https://ror.org/031n1rn61","country_code":"US","type":"other","lineage":["https://openalex.org/I4210124077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anusha Prakash","raw_affiliation_strings":["Duke Institute for Health Innovation, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke Institute for Health Innovation, Durham, NC, USA","institution_ids":["https://openalex.org/I4210124077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011563355","display_name":"William Ratliff","orcid":"https://orcid.org/0000-0003-4015-3805"},"institutions":[{"id":"https://openalex.org/I4210124077","display_name":"Duke Institute for Health Innovation","ror":"https://ror.org/031n1rn61","country_code":"US","type":"other","lineage":["https://openalex.org/I4210124077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William Ratliff","raw_affiliation_strings":["Duke Institute for Health Innovation, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke Institute for Health Innovation, Durham, NC, USA","institution_ids":["https://openalex.org/I4210124077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033019632","display_name":"Michael Gao","orcid":"https://orcid.org/0000-0003-0534-4403"},"institutions":[{"id":"https://openalex.org/I4210124077","display_name":"Duke Institute for Health Innovation","ror":"https://ror.org/031n1rn61","country_code":"US","type":"other","lineage":["https://openalex.org/I4210124077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Gao","raw_affiliation_strings":["Duke Institute for Health Innovation, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke Institute for Health Innovation, Durham, NC, USA","institution_ids":["https://openalex.org/I4210124077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038006084","display_name":"Srikanth Muthya","orcid":null},"institutions":[{"id":"https://openalex.org/I99978038","display_name":"Core Laboratories (United States)","ror":"https://ror.org/00scjy223","country_code":"US","type":"company","lineage":["https://openalex.org/I99978038"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Srikanth Muthya","raw_affiliation_strings":["Cohere Med Inc, 110 Corcoran St, 5th Floor, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cohere Med Inc, 110 Corcoran St, 5th Floor, Durham, NC, USA","institution_ids":["https://openalex.org/I99978038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110089481","display_name":"Ajit J. Thomas","orcid":null},"institutions":[{"id":"https://openalex.org/I99978038","display_name":"Core Laboratories (United States)","ror":"https://ror.org/00scjy223","country_code":"US","type":"company","lineage":["https://openalex.org/I99978038"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ajit Thomas","raw_affiliation_strings":["Cohere Med Inc, 110 Corcoran St, 5th Floor, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cohere Med Inc, 110 Corcoran St, 5th Floor, Durham, NC, USA","institution_ids":["https://openalex.org/I99978038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023011612","display_name":"Jennifer L. Eaton","orcid":null},"institutions":[{"id":"https://openalex.org/I1294639003","display_name":"Summa Health System","ror":"https://ror.org/03p6fpw74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1294639003"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer L. Eaton","raw_affiliation_strings":["Summa Health Research & Innovation, Akron, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Summa Health Research & Innovation, Akron, OH, USA","institution_ids":["https://openalex.org/I1294639003"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035088083","display_name":"Matt Gardner","orcid":"https://orcid.org/0000-0001-8458-1727"},"institutions":[{"id":"https://openalex.org/I4210124077","display_name":"Duke Institute for Health Innovation","ror":"https://ror.org/031n1rn61","country_code":"US","type":"other","lineage":["https://openalex.org/I4210124077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matt Gardner","raw_affiliation_strings":["Duke Institute for Health Innovation, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke Institute for Health Innovation, Durham, NC, USA","institution_ids":["https://openalex.org/I4210124077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007955926","display_name":"Marshall Nichols","orcid":"https://orcid.org/0000-0002-0969-1982"},"institutions":[{"id":"https://openalex.org/I4210124077","display_name":"Duke Institute for Health Innovation","ror":"https://ror.org/031n1rn61","country_code":"US","type":"other","lineage":["https://openalex.org/I4210124077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marshall Nichols","raw_affiliation_strings":["Duke Institute for Health Innovation, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke Institute for Health Innovation, Durham, NC, USA","institution_ids":["https://openalex.org/I4210124077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044677056","display_name":"Mike Revoir","orcid":"https://orcid.org/0000-0003-1834-9078"},"institutions":[{"id":"https://openalex.org/I4210124077","display_name":"Duke Institute for Health Innovation","ror":"https://ror.org/031n1rn61","country_code":"US","type":"other","lineage":["https://openalex.org/I4210124077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mike Revoir","raw_affiliation_strings":["Duke Institute for Health Innovation, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke Institute for Health Innovation, Durham, NC, USA","institution_ids":["https://openalex.org/I4210124077"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092240985","display_name":"Dustin Tart","orcid":null},"institutions":[{"id":"https://openalex.org/I4210153043","display_name":"Duke University Hospital","ror":"https://ror.org/04bct7p84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876","https://openalex.org/I4210144876","https://openalex.org/I4210153043"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dustin Tart","raw_affiliation_strings":["Duke University Hospital, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Hospital, Durham, NC, USA","institution_ids":["https://openalex.org/I4210153043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058800474","display_name":"Cara O\u2019Brien","orcid":"https://orcid.org/0000-0002-5519-7344"},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210153043","display_name":"Duke University Hospital","ror":"https://ror.org/04bct7p84","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876","https://openalex.org/I4210144876","https://openalex.org/I4210153043"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cara O\u2019Brien","raw_affiliation_strings":["Department of Medicine, Duke University School of Medicine, Durham, NC, USA","Duke University Hospital, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Duke University School of Medicine, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Duke University Hospital, Durham, NC, USA","institution_ids":["https://openalex.org/I4210153043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014777482","display_name":"Manesh R. Patel","orcid":"https://orcid.org/0000-0002-2393-0855"},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Manesh Patel","raw_affiliation_strings":["Department of Medicine, Duke University School of Medicine, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Duke University School of Medicine, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009455981","display_name":"Suresh Balu","orcid":"https://orcid.org/0000-0003-4929-9130"},"institutions":[{"id":"https://openalex.org/I4210124077","display_name":"Duke Institute for Health Innovation","ror":"https://ror.org/031n1rn61","country_code":"US","type":"other","lineage":["https://openalex.org/I4210124077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suresh Balu","raw_affiliation_strings":["Duke Institute for Health Innovation, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke Institute for Health Innovation, Durham, NC, USA","institution_ids":["https://openalex.org/I4210124077"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089062751","display_name":"Mark Sendak","orcid":"https://orcid.org/0000-0001-5828-4497"},"institutions":[{"id":"https://openalex.org/I4210124077","display_name":"Duke Institute for Health Innovation","ror":"https://ror.org/031n1rn61","country_code":"US","type":"other","lineage":["https://openalex.org/I4210124077"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark Sendak","raw_affiliation_strings":["Duke Institute for Health Innovation, Durham, NC, USA. mark.sendak@duke.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke Institute for Health Innovation, Durham, NC, USA. mark.sendak@duke.edu","institution_ids":["https://openalex.org/I4210124077"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5089062751"],"corresponding_institution_ids":["https://openalex.org/I4210124077"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":10.3389,"has_fulltext":true,"cited_by_count":11,"citation_normalized_percentile":{"value":0.98591812,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"8","issue":"1","first_page":"350","last_page":"350"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9915000200271606,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.9768999814987183,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/generalizability-theory","display_name":"Generalizability theory","score":0.9661521315574646},{"id":"https://openalex.org/keywords/sepsis","display_name":"Sepsis","score":0.6344798803329468},{"id":"https://openalex.org/keywords/external-validity","display_name":"External validity","score":0.5863461494445801},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.49771764874458313},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4764443039894104},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.42071765661239624},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.3634059429168701},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3568611145019531},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.133966326713562},{"id":"https://openalex.org/keywords/social-psychology","display_name":"Social psychology","score":0.0946577787399292},{"id":"https://openalex.org/keywords/developmental-psychology","display_name":"Developmental psychology","score":0.07417473196983337}],"concepts":[{"id":"https://openalex.org/C27158222","wikidata":"https://www.wikidata.org/wiki/Q5532422","display_name":"Generalizability theory","level":2,"score":0.9661521315574646},{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.6344798803329468},{"id":"https://openalex.org/C174106493","wikidata":"https://www.wikidata.org/wiki/Q1057880","display_name":"External validity","level":2,"score":0.5863461494445801},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.49771764874458313},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4764443039894104},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.42071765661239624},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3634059429168701},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3568611145019531},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.133966326713562},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.0946577787399292},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.07417473196983337}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-025-01664-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01664-5","pdf_url":"https://www.nature.com/articles/s41746-025-01664-5.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:40500319","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40500319","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:8201502c15d045d7abbb23ab561b87ac","is_oa":true,"landing_page_url":"https://doaj.org/article/8201502c15d045d7abbb23ab561b87ac","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 8, Iss 1, Pp 1-10 (2025)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12159134","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12159134","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-025-01664-5","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01664-5","pdf_url":"https://www.nature.com/articles/s41746-025-01664-5.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1959398708","display_name":null,"funder_award_id":"R42 GM144999-03","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8969635935","display_name":null,"funder_award_id":"R42 GM144999","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4411221282.pdf","grobid_xml":"https://content.openalex.org/works/W4411221282.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1943063538","https://openalex.org/W1969760843","https://openalex.org/W1993397663","https://openalex.org/W2024683287","https://openalex.org/W2039251546","https://openalex.org/W2073316020","https://openalex.org/W2087203965","https://openalex.org/W2145889332","https://openalex.org/W2523834880","https://openalex.org/W2599245417","https://openalex.org/W2604972438","https://openalex.org/W2728189178","https://openalex.org/W2745765770","https://openalex.org/W2768083064","https://openalex.org/W2782117851","https://openalex.org/W2883566781","https://openalex.org/W2895072154","https://openalex.org/W2912904466","https://openalex.org/W2945543078","https://openalex.org/W2968919852","https://openalex.org/W2972915925","https://openalex.org/W2998524378","https://openalex.org/W2998853022","https://openalex.org/W3005410610","https://openalex.org/W3005797804","https://openalex.org/W3015460073","https://openalex.org/W3016555942","https://openalex.org/W3087893815","https://openalex.org/W3129441165","https://openalex.org/W3154702719","https://openalex.org/W3159623667","https://openalex.org/W3174786846","https://openalex.org/W3189244054","https://openalex.org/W3194087995","https://openalex.org/W4200202919","https://openalex.org/W4221070183","https://openalex.org/W4226042058","https://openalex.org/W4282960414","https://openalex.org/W4286489697","https://openalex.org/W4290852327","https://openalex.org/W4362506020","https://openalex.org/W4385762558","https://openalex.org/W4393086261"],"related_works":["https://openalex.org/W2035068594","https://openalex.org/W2486564388","https://openalex.org/W4386122788","https://openalex.org/W2961085424","https://openalex.org/W4306674287","https://openalex.org/W1501673046","https://openalex.org/W4206380735","https://openalex.org/W4387369504","https://openalex.org/W4394896187","https://openalex.org/W3170094116"],"abstract_inverted_index":{"Sepsis":[0,23,117],"accounts":[1],"for":[2],"a":[3,28,59,121],"substantial":[4],"portion":[5],"of":[6,14,61,115],"global":[7],"deaths":[8],"and":[9,33,37,63,72,85,100,129,132,137],"healthcare":[10,31],"costs.":[11],"The":[12,49,93],"objective":[13],"this":[15],"reproducibility":[16,114],"study":[17,50],"is":[18],"to":[19,55,98,106],"validate":[20],"Duke":[21],"Health's":[22,46],"Watch":[24,118],"ML":[25],"model,":[26],"in":[27,40,120],"new":[29],"community":[30,122],"setting":[32,125],"assess":[34],"its":[35,127],"performance":[36,131],"clinical":[38],"utility":[39],"early":[41],"sepsis":[42,57],"detection":[43],"at":[44],"Summa":[45],"emergency":[47],"departments.":[48],"analyzed":[51],"the":[52,86,101,109,113,116],"model's":[53],"ability":[54],"predict":[56],"using":[58,67],"combination":[60],"static":[62],"dynamic":[64],"patient":[65],"data":[66],"205,005":[68],"encounters":[69],"between":[70],"2020":[71],"2021":[73],"from":[74,96,104],"101,584":[75],"unique":[76],"patients.":[77],"54.7%":[78],"(n":[79],"=":[80],"112,223)":[81],"patients":[82],"were":[83],"female":[84],"average":[87],"age":[88],"was":[89],"50":[90],"(IQR":[91],"[38,71]).":[92],"AUROC":[94],"ranged":[95,103],"0.906":[97],"0.960,":[99],"AUPRC":[102],"0.177":[105],"0.252":[107],"across":[108,134],"four":[110],"sites.":[111],"Ultimately,":[112],"model":[119],"health":[123],"system":[124],"confirmed":[126],"strong":[128],"robust":[130],"portability":[133],"different":[135],"geographical":[136],"demographic":[138],"contexts":[139],"with":[140],"little":[141],"variation.":[142]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":3}],"updated_date":"2026-06-24T13:16:06.693445","created_date":"2025-10-10T00:00:00"}