{"id":"https://openalex.org/W4406983730","doi":"https://doi.org/10.1038/s41746-025-01441-4","title":"Digital twin driven electrode optimization for wearable bladder monitoring via bioimpedance","display_name":"Digital twin driven electrode optimization for wearable bladder monitoring via bioimpedance","publication_year":2025,"publication_date":"2025-01-30","ids":{"openalex":"https://openalex.org/W4406983730","doi":"https://doi.org/10.1038/s41746-025-01441-4","pmid":"https://pubmed.ncbi.nlm.nih.gov/39885231"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-025-01441-4","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01441-4","pdf_url":null,"source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1038/s41746-025-01441-4","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088732340","display_name":"H. Trask Crane","orcid":"https://orcid.org/0000-0002-1727-402X"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"H. Trask Crane","raw_affiliation_strings":["School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA. hcrane3@gatech.edu"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA. hcrane3@gatech.edu","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102932398","display_name":"John A. Berkebile","orcid":"https://orcid.org/0000-0003-0263-7083"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John A. Berkebile","raw_affiliation_strings":["School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065186117","display_name":"Samer Mabrouk","orcid":"https://orcid.org/0000-0001-9534-6319"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samer Mabrouk","raw_affiliation_strings":["School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA","institution_ids":["https://openalex.org/I130701444"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5116085920","display_name":"Nicholas Riccardelli","orcid":null},"institutions":[{"id":"https://openalex.org/I4210162366","display_name":"Covington and Burling","ror":"https://ror.org/05bhzk792","country_code":"US","type":"other","lineage":["https://openalex.org/I4210162366"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicholas Riccardelli","raw_affiliation_strings":["Urology and Critical Care, BD, Covington, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Urology and Critical Care, BD, Covington, GA, USA","institution_ids":["https://openalex.org/I4210162366"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5076927036","display_name":"Omer T. Inan","orcid":"https://orcid.org/0000-0002-7952-1794"},"institutions":[{"id":"https://openalex.org/I130701444","display_name":"Georgia Institute of Technology","ror":"https://ror.org/01zkghx44","country_code":"US","type":"education","lineage":["https://openalex.org/I130701444"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Omer T. Inan","raw_affiliation_strings":["School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA","institution_ids":["https://openalex.org/I130701444"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5088732340"],"corresponding_institution_ids":[],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":5.0082,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.9367227,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"8","issue":"1","first_page":"73","last_page":"73"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11700","display_name":"Hemodynamic Monitoring and Therapy","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11778","display_name":"Electrical and Bioimpedance Tomography","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12279","display_name":"Body Composition Measurement Techniques","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wearable-computer","display_name":"Wearable computer","score":0.7485681176185608},{"id":"https://openalex.org/keywords/electrode","display_name":"Electrode","score":0.5824042558670044},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5090605616569519},{"id":"https://openalex.org/keywords/biomedical-engineering","display_name":"Biomedical engineering","score":0.4465819299221039},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.2616676092147827},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.23322182893753052},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.17328941822052002}],"concepts":[{"id":"https://openalex.org/C150594956","wikidata":"https://www.wikidata.org/wiki/Q1334829","display_name":"Wearable computer","level":2,"score":0.7485681176185608},{"id":"https://openalex.org/C17525397","wikidata":"https://www.wikidata.org/wiki/Q176140","display_name":"Electrode","level":2,"score":0.5824042558670044},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5090605616569519},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.4465819299221039},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.2616676092147827},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.23322182893753052},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.17328941822052002},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-025-01441-4","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01441-4","pdf_url":null,"source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:39885231","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39885231","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11782588","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11782588","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11782588/pdf/41746_2025_Article_1441.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:c960de284a234bbb95050703ccfa2a7f","is_oa":true,"landing_page_url":"https://doaj.org/article/c960de284a234bbb95050703ccfa2a7f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 8, Iss 1, Pp 1-11 (2025)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41746-025-01441-4","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-025-01441-4","pdf_url":null,"source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Affordable and clean energy","score":0.8199999928474426,"id":"https://metadata.un.org/sdg/7"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320317364","display_name":"BD","ror":"https://ror.org/048vrgr14"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1903804808","https://openalex.org/W2005233497","https://openalex.org/W2015317507","https://openalex.org/W2027118734","https://openalex.org/W2027404616","https://openalex.org/W2053227292","https://openalex.org/W2055280557","https://openalex.org/W2089400477","https://openalex.org/W2110965436","https://openalex.org/W2113761410","https://openalex.org/W2127890285","https://openalex.org/W2135046866","https://openalex.org/W2156515188","https://openalex.org/W2480921134","https://openalex.org/W2485168708","https://openalex.org/W2541795897","https://openalex.org/W2759159382","https://openalex.org/W2789943003","https://openalex.org/W2868763662","https://openalex.org/W2883605219","https://openalex.org/W2885209060","https://openalex.org/W2903905024","https://openalex.org/W2943245334","https://openalex.org/W2960333166","https://openalex.org/W2983327464","https://openalex.org/W3003372094","https://openalex.org/W3010295363","https://openalex.org/W3036641818","https://openalex.org/W3038748011","https://openalex.org/W3043330105","https://openalex.org/W3180285308","https://openalex.org/W3198127988","https://openalex.org/W4200430797","https://openalex.org/W4210541465","https://openalex.org/W4211082352","https://openalex.org/W4289912343","https://openalex.org/W4317625880","https://openalex.org/W4318832769","https://openalex.org/W4323044334","https://openalex.org/W4323307285","https://openalex.org/W4360993894","https://openalex.org/W4362522959","https://openalex.org/W4379233562"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Monitoring":[0],"fluid":[1,17,143],"intake":[2],"and":[3,33,135],"output":[4],"for":[5,101],"congestive":[6],"heart":[7],"failure":[8],"(CHF)":[9],"patients":[10,134],"is":[11],"an":[12,72,79],"essential":[13],"tool":[14],"to":[15,67,99,128],"prevent":[16],"overload,":[18],"a":[19,47,55,112,138],"principal":[20],"cause":[21],"of":[22,43,110,142],"hospital":[23],"admissions.":[24],"Addressing":[25],"this,":[26],"bladder":[27],"volume":[28,82],"measurement":[29,90],"systems":[30],"utilizing":[31],"bioimpedance":[32,120],"electrical":[34],"impedance":[35],"tomography":[36],"have":[37],"been":[38],"proposed,":[39],"with":[40,137],"limited":[41],"exploration":[42],"continuous":[44],"monitoring":[45,124],"within":[46],"wearable":[48],"design.":[49],"Advancing":[50],"this":[51],"format,":[52],"we":[53,63,106,126],"developed":[54],"conductivity":[56],"digital":[57],"twin":[58],"from":[59],"radiological":[60],"data,":[61],"where":[62],"performed":[64],"exhaustive":[65],"simulations":[66],"optimize":[68],"electrode":[69],"sensitivity":[70],"on":[71,118],"individual":[73],"basis.":[74],"Our":[75],"optimized":[76],"placement":[77],"demonstrated":[78],"efficient":[80],"proof-of-concept":[81],"estimation":[83],"that":[84],"required":[85],"as":[86,88],"few":[87],"seven":[89],"frames":[91],"while":[92],"maintaining":[93],"low":[94],"errors":[95],"(CI":[96],"95%":[97],"-1.11%":[98],"1.00%)":[100],"volumes":[102],"\u2265100":[103],"mL.":[104],"Additionally,":[105],"quantify":[107],"the":[108,119],"impact":[109],"ascites,":[111],"common":[113],"confounding":[114],"condition":[115],"in":[116],"CHF,":[117],"signal.":[121],"By":[122],"improving":[123],"technology,":[125],"aim":[127],"reduce":[129],"CHF":[130],"mortality":[131],"by":[132],"empowering":[133],"clinicians":[136],"more":[139],"thorough":[140],"understanding":[141],"status.":[144]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}
