{"id":"https://openalex.org/W4404060993","doi":"https://doi.org/10.1038/s41746-024-01308-0","title":"Artificial intelligence applied to coronary artery calcium scans (AI-CAC) significantly improves cardiovascular events prediction","display_name":"Artificial intelligence applied to coronary artery calcium scans (AI-CAC) significantly improves cardiovascular events prediction","publication_year":2024,"publication_date":"2024-11-05","ids":{"openalex":"https://openalex.org/W4404060993","doi":"https://doi.org/10.1038/s41746-024-01308-0","pmid":"https://pubmed.ncbi.nlm.nih.gov/39501071"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-024-01308-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-024-01308-0","pdf_url":"https://www.nature.com/articles/s41746-024-01308-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-024-01308-0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002861692","display_name":"Morteza Naghavi","orcid":"https://orcid.org/0000-0001-8112-175X"},"institutions":[{"id":"https://openalex.org/I1295876152","display_name":"Houston Methodist","ror":"https://ror.org/027zt9171","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295876152"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Morteza Naghavi","raw_affiliation_strings":["HeartLung.AI, Houston, TX, 77021, USA. mn@vp.org","HeartLung.AI, Houston, TX, 77021, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HeartLung.AI, Houston, TX, 77021, USA. mn@vp.org","institution_ids":["https://openalex.org/I1295876152"]},{"raw_affiliation_string":"HeartLung.AI, Houston, TX, 77021, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060527966","display_name":"Anthony P. Reeves","orcid":"https://orcid.org/0000-0002-1451-3080"},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anthony P. Reeves","raw_affiliation_strings":["Department of Electrical and Computer Engineering, Cornell University, Ithaca, NY, 14853, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, Cornell University, Ithaca, NY, 14853, USA","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091999629","display_name":"K. Atlas","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kyle Atlas","raw_affiliation_strings":["HeartLung.AI, Houston, TX, 77021, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"HeartLung.AI, Houston, TX, 77021, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101962576","display_name":"Chenyu Zhang","orcid":"https://orcid.org/0000-0002-9799-8772"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chenyu Zhang","raw_affiliation_strings":["HeartLung.AI, Houston, TX, 77021, USA"],"raw_orcid":"https://orcid.org/0000-0002-9799-8772","affiliations":[{"raw_affiliation_string":"HeartLung.AI, Houston, TX, 77021, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091999628","display_name":"Thomas Atlas","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Thomas Atlas","raw_affiliation_strings":["Tustin Teleradiology, Tustin, CA, 92780, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tustin Teleradiology, Tustin, CA, 92780, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008905381","display_name":"Claudia I. Henschke","orcid":"https://orcid.org/0000-0002-6085-5305"},"institutions":[{"id":"https://openalex.org/I4210101641","display_name":"Mount Sinai Hospital","ror":"https://ror.org/019jr0130","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210101641","https://openalex.org/I4210149743"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Claudia I. Henschke","raw_affiliation_strings":["Mount Sinai Hospital, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mount Sinai Hospital, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I4210101641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108437389","display_name":"David F. Yankelevitz","orcid":null},"institutions":[{"id":"https://openalex.org/I4210101641","display_name":"Mount Sinai Hospital","ror":"https://ror.org/019jr0130","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210101641","https://openalex.org/I4210149743"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David F. Yankelevitz","raw_affiliation_strings":["Mount Sinai Hospital, New York, NY, 10029, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mount Sinai Hospital, New York, NY, 10029, USA","institution_ids":["https://openalex.org/I4210101641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079665496","display_name":"Matthew J. Budoff","orcid":"https://orcid.org/0000-0002-9616-1946"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Matthew J. Budoff","raw_affiliation_strings":["The Lundquist Institute, Torrance, CA, 90502, USA"],"raw_orcid":"https://orcid.org/0000-0002-9616-1946","affiliations":[{"raw_affiliation_string":"The Lundquist Institute, Torrance, CA, 90502, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100407436","display_name":"Dong Li","orcid":"https://orcid.org/0000-0002-3897-7322"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dong Li","raw_affiliation_strings":["The Lundquist Institute, Torrance, CA, 90502, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Lundquist Institute, Torrance, CA, 90502, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112636975","display_name":"Sion Roy","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sion K. Roy","raw_affiliation_strings":["The Lundquist Institute, Torrance, CA, 90502, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Lundquist Institute, Torrance, CA, 90502, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101423613","display_name":"Khurram Nasir","orcid":null},"institutions":[{"id":"https://openalex.org/I4210109259","display_name":"Methodist Hospital","ror":"https://ror.org/01r5p9y80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802827176","https://openalex.org/I4210109259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Khurram Nasir","raw_affiliation_strings":["Houston Methodist Hospital, Houston, TX, 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Houston Methodist Hospital, Houston, TX, 77030, USA","institution_ids":["https://openalex.org/I4210109259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086707068","display_name":"Sabee Molloi","orcid":"https://orcid.org/0000-0003-1852-4913"},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sabee Molloi","raw_affiliation_strings":["Department of Radiology, University of California Irvine, Irvine, CA, 92697, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, University of California Irvine, Irvine, CA, 92697, USA","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089434484","display_name":"Zahi A. Fayad","orcid":"https://orcid.org/0000-0002-3439-7347"},"institutions":[{"id":"https://openalex.org/I4210109259","display_name":"Methodist Hospital","ror":"https://ror.org/01r5p9y80","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802827176","https://openalex.org/I4210109259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zahi Fayad","raw_affiliation_strings":["Houston Methodist Hospital, Houston, TX, 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Houston Methodist Hospital, Houston, TX, 77030, USA","institution_ids":["https://openalex.org/I4210109259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064279763","display_name":"Michael V. McConnell","orcid":"https://orcid.org/0000-0001-8743-0932"},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael V. McConnell","raw_affiliation_strings":["Cardiovascular Medicine, Stanford School of Medicine, Stanford, CA, 94305, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Medicine, Stanford School of Medicine, Stanford, CA, 94305, USA","institution_ids":["https://openalex.org/I4210137306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031773367","display_name":"Ioannis A. Kakadiaris","orcid":"https://orcid.org/0000-0002-0591-1079"},"institutions":[{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ioannis Kakadiaris","raw_affiliation_strings":["The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA","institution_ids":["https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051674313","display_name":"David J. Maron","orcid":"https://orcid.org/0000-0002-4867-8588"},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David J. Maron","raw_affiliation_strings":["Cardiovascular Medicine, Stanford School of Medicine, Stanford, CA, 94305, USA"],"raw_orcid":"https://orcid.org/0000-0002-4867-8588","affiliations":[{"raw_affiliation_string":"Cardiovascular Medicine, Stanford School of Medicine, Stanford, CA, 94305, USA","institution_ids":["https://openalex.org/I4210137306"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000545244","display_name":"Jagat Narula","orcid":"https://orcid.org/0000-0002-0280-3996"},"institutions":[{"id":"https://openalex.org/I919571938","display_name":"The University of Texas Health Science Center at Houston","ror":"https://ror.org/03gds6c39","country_code":"US","type":"education","lineage":["https://openalex.org/I919571938"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jagat Narula","raw_affiliation_strings":["The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA","institution_ids":["https://openalex.org/I919571938"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000965115","display_name":"Kim A. Williams","orcid":"https://orcid.org/0000-0001-9858-5761"},"institutions":[{"id":"https://openalex.org/I142740786","display_name":"University of Louisville","ror":"https://ror.org/01ckdn478","country_code":"US","type":"education","lineage":["https://openalex.org/I142740786"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kim Williams","raw_affiliation_strings":["University of Louisville, Louisville, KY, 40292, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Louisville, Louisville, KY, 40292, USA","institution_ids":["https://openalex.org/I142740786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003094687","display_name":"Prediman K. Shah","orcid":"https://orcid.org/0000-0002-6351-8291"},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prediman K. Shah","raw_affiliation_strings":["Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074117194","display_name":"Daniel Levy","orcid":"https://orcid.org/0000-0003-1843-8724"},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart Lung and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Levy","raw_affiliation_strings":["Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20824, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, 20824, USA","institution_ids":["https://openalex.org/I4210106489","https://openalex.org/I1299303238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086073841","display_name":"Nathan D. Wong","orcid":"https://orcid.org/0000-0003-1102-7324"},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nathan D. Wong","raw_affiliation_strings":["Heart Disease Prevention Program, Division of Cardiology, University of California Irvine, Irvine, CA, 92697, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Heart Disease Prevention Program, Division of Cardiology, University of California Irvine, Irvine, CA, 92697, USA","institution_ids":["https://openalex.org/I204250578"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":21,"corresponding_author_ids":["https://openalex.org/A5002861692"],"corresponding_institution_ids":["https://openalex.org/I1295876152"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":10.108,"has_fulltext":true,"cited_by_count":26,"citation_normalized_percentile":{"value":0.98703486,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"7","issue":"1","first_page":"309","last_page":"309"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.9732000231742859,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coronary-artery-calcium","display_name":"Coronary artery calcium","score":0.7634277939796448},{"id":"https://openalex.org/keywords/cardiology","display_name":"Cardiology","score":0.6357170343399048},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.6279467344284058},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.45433858036994934},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"Coronary artery disease","score":0.39296817779541016}],"concepts":[{"id":"https://openalex.org/C2994533308","wikidata":"https://www.wikidata.org/wiki/Q5629407","display_name":"Coronary artery calcium","level":3,"score":0.7634277939796448},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6357170343399048},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6279467344284058},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45433858036994934},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.39296817779541016}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1038/s41746-024-01308-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-024-01308-0","pdf_url":"https://www.nature.com/articles/s41746-024-01308-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:39501071","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39501071","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:escholarship.org:ark:/13030/qt1fq6z4kq","is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/1fq6z4kq","pdf_url":"https://escholarship.org/content/qt1fq6z4kq/qt1fq6z4kq.pdf","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, vol 7, iss 1","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11538462","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11538462","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11538462/pdf/41746_2024_Article_1308.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"},{"id":"pmh:ark:/13030/qt1fq6z4kq","is_oa":false,"landing_page_url":null,"pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},{"id":"pmh:oai:doaj.org/article:5dcdbca0040f43b1b76088122904b1dd","is_oa":true,"landing_page_url":"https://doaj.org/article/5dcdbca0040f43b1b76088122904b1dd","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 7, Iss 1, Pp 1-9 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41746-024-01308-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-024-01308-0","pdf_url":"https://www.nature.com/articles/s41746-024-01308-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G1269631540","display_name":null,"funder_award_id":"75N92020D00005","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1276754516","display_name":null,"funder_award_id":"N01-HC-95160","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1294553593","display_name":null,"funder_award_id":"N01-HC-95161","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G1412221515","display_name":null,"funder_award_id":"75N92020D00003","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1446319095","display_name":null,"funder_award_id":"UL1-TR-000040","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G1516086731","display_name":null,"funder_award_id":"N01-HC-95159","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G1518934888","display_name":null,"funder_award_id":"R01HL146666","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1539384734","display_name":null,"funder_award_id":"75N92020D00001","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1558725192","display_name":null,"funder_award_id":"N01-HC-95161","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G1657168240","display_name":null,"funder_award_id":"UL1-TR-001420","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1740741465","display_name":null,"funder_award_id":"N01-HC-95168","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G1803853571","display_name":null,"funder_award_id":"75N92020D00006","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1877939937","display_name":null,"funder_award_id":"N01-HC-95161","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1956357178","display_name":null,"funder_award_id":"N01-HC-95169","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G1969827686","display_name":null,"funder_award_id":"N01-HC-95166","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G1983464145","display_name":null,"funder_award_id":"N01-HC-95168","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G2095942735","display_name":null,"funder_award_id":"UL1-TR","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G2238490387","display_name":null,"funder_award_id":"N01-HC-95169","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2435477651","display_name":null,"funder_award_id":"N01-HC-95166","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G2580996367","display_name":null,"funder_award_id":"75N92020D00007","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2623405628","display_name":null,"funder_award_id":"N01-HC-95166","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2639998763","display_name":null,"funder_award_id":"N01-HC-95165","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2726417417","display_name":null,"funder_award_id":"N01-HC-95162","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G2750540916","display_name":null,"funder_award_id":"N01-HC-95164","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G2769513335","display_name":null,"funder_award_id":"2R42AR070713","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G2779429302","display_name":null,"funder_award_id":"N01-HC-95160","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G3161396180","display_name":null,"funder_award_id":"N01-HC-95164","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G3252259982","display_name":null,"funder_award_id":"N01-HC-95162","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G3359243492","display_name":null,"funder_award_id":"UL1-TR-001420","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3570589137","display_name":null,"funder_award_id":"75N92020D00002","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3575057044","display_name":null,"funder_award_id":"UL1-TR-001079","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3595232572","display_name":null,"funder_award_id":"N01-HC-95159","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G3676546685","display_name":null,"funder_award_id":"75N92020D00006","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3826568287","display_name":null,"funder_award_id":"N01-HC-95165","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3982441736","display_name":null,"funder_award_id":"N01-HC-95167","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G3983070977","display_name":null,"funder_award_id":"UL1-TR-001079","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G4036023366","display_name":null,"funder_award_id":"N01-HC-95167","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G4101536646","display_name":null,"funder_award_id":"N01-HC-95159","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4118980254","display_name":null,"funder_award_id":"HHSN268201500003I","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G4146420730","display_name":null,"funder_award_id":"UL1-TR-000040","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4186273061","display_name":null,"funder_award_id":"N01-HC-95165","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G4266184307","display_name":null,"funder_award_id":"N01-HC-95163","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4309390892","display_name":null,"funder_award_id":"N01-HC-95160","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G4563812999","display_name":null,"funder_award_id":"75N92020D00005","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4590187187","display_name":null,"funder_award_id":"HHSN268201500003I","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G4842175797","display_name":null,"funder_award_id":"UL1-TR-000040","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G4986157935","display_name":null,"funder_award_id":"N01-HC-95166","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G5075046117","display_name":null,"funder_award_id":"N01-HC-95169","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G5138253846","display_name":null,"funder_award_id":"N01-HC-95168","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G514410172","display_name":null,"funder_award_id":"75N92020D00003","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G535872069","display_name":null,"funder_award_id":"N01-HC-95164","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5439146981","display_name":null,"funder_award_id":"UL1-TR-001079","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G5493479587","display_name":null,"funder_award_id":"UL1-TR-001420","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G5653954166","display_name":null,"funder_award_id":"N01-HC-95163","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G575289800","display_name":null,"funder_award_id":"N01-HC-95163","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6522400586","display_name":null,"funder_award_id":"UL1-TR-001420","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G6742279884","display_name":null,"funder_award_id":"HHSN268201500003I","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6789189252","display_name":null,"funder_award_id":"N01-HC-95168","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6798586005","display_name":null,"funder_award_id":"75N92020D00004","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6855506055","display_name":null,"funder_award_id":"N01-HC-95162","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6856766826","display_name":null,"funder_award_id":"N01-HC-95167","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G6899060999","display_name":null,"funder_award_id":"UL1-TR-001079","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G6951716892","display_name":null,"funder_award_id":"N01-HC-95160","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7062576961","display_name":null,"funder_award_id":"N01-HC-95159","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7166352866","display_name":null,"funder_award_id":"N01-HC-95165","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G7462069030","display_name":null,"funder_award_id":"75N92020D00007","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7610800535","display_name":null,"funder_award_id":"N01-HC-95167","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7826153973","display_name":null,"funder_award_id":"75N92020D00001","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G7886706545","display_name":null,"funder_award_id":"N01-HC-95161","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G7924587209","display_name":null,"funder_award_id":"N01-HC-95163","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G797182136","display_name":null,"funder_award_id":"UL1-TR-000040","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G8068815734","display_name":null,"funder_award_id":"N01-HC-95162","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8086875265","display_name":null,"funder_award_id":"2R42AR070713","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8145863542","display_name":null,"funder_award_id":"N01-HC-95164","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G842756795","display_name":null,"funder_award_id":"75N92020D00002","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G8714546325","display_name":null,"funder_award_id":"HHSN268201500003I","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8733954309","display_name":null,"funder_award_id":"N01-HC-95169","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G8761005068","display_name":null,"funder_award_id":"75N92020D00004","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8852914737","display_name":null,"funder_award_id":"UL1-TR-","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4404060993.pdf"},"referenced_works_count":37,"referenced_works":["https://openalex.org/W2014951154","https://openalex.org/W2036868481","https://openalex.org/W2048987052","https://openalex.org/W2064993645","https://openalex.org/W2093352601","https://openalex.org/W2105836437","https://openalex.org/W2112316706","https://openalex.org/W2115752970","https://openalex.org/W2120579447","https://openalex.org/W2130289472","https://openalex.org/W2153785016","https://openalex.org/W2156097706","https://openalex.org/W2159449917","https://openalex.org/W2167830562","https://openalex.org/W2168536722","https://openalex.org/W2468136027","https://openalex.org/W2482739936","https://openalex.org/W2562439620","https://openalex.org/W2604847258","https://openalex.org/W2899921784","https://openalex.org/W2900034165","https://openalex.org/W3001764054","https://openalex.org/W3014974815","https://openalex.org/W3112701542","https://openalex.org/W3129818723","https://openalex.org/W3201699736","https://openalex.org/W3207446686","https://openalex.org/W3217183692","https://openalex.org/W4291238401","https://openalex.org/W4311243826","https://openalex.org/W4383218413","https://openalex.org/W4384945213","https://openalex.org/W4392503039","https://openalex.org/W4395045053","https://openalex.org/W4395085091","https://openalex.org/W4400066362","https://openalex.org/W4404359539"],"related_works":["https://openalex.org/W3183948672","https://openalex.org/W3173606202","https://openalex.org/W3110381201","https://openalex.org/W2899084033","https://openalex.org/W2778153218","https://openalex.org/W2748952813","https://openalex.org/W1531601525","https://openalex.org/W2417866357","https://openalex.org/W4285736944","https://openalex.org/W3142553016"],"abstract_inverted_index":{"Coronary":[0],"artery":[1],"calcium":[2],"(CAC)":[3],"scans":[4,33,58],"contain":[5],"valuable":[6],"information":[7],"beyond":[8],"the":[9,72,136,146],"Agatston":[10,98,141,147],"Score":[11],"which":[12],"is":[13],"currently":[14],"reported":[15],"for":[16,95,117,149],"predicting":[17,150],"coronary":[18],"heart":[19,39],"disease":[20],"(CHD)":[21],"only.":[22],"We":[23,45],"examined":[24],"whether":[25],"new":[26],"artificial":[27],"intelligence":[28],"(AI)":[29],"applied":[30,46],"to":[31,56],"CAC":[32,57,137],"can":[34],"predict":[35],"non-CHD":[36],"events,":[37],"including":[38,123],"failure,":[40],"atrial":[41],"fibrillation,":[42],"and":[43,52,92,110],"stroke.":[44],"AI-enabled":[47],"automated":[48],"cardiac":[49],"chambers":[50],"volumetry":[51],"calcified":[53],"plaque":[54,121],"characterization":[55],"(AI-CAC)":[59],"of":[60,75,80,129],"5830":[61],"asymptomatic":[62],"individuals":[63],"(52.2%":[64],"women,":[65],"age":[66],"61.7":[67],"\u00b1":[68],"10.2":[69],"years)":[70],"in":[71,135],"multi-ethnic":[73],"study":[74],"atherosclerosis":[76],"during":[77],"15":[78],"years":[79],"follow-up,":[81],"1773":[82],"CVD":[83,152],"events":[84],"accrued.":[85],"The":[86],"AUC":[87],"at":[88],"1-,":[89],"5-,":[90],"10-,":[91],"15-year":[93],"follow-up":[94],"AI-CAC":[96,120,143],"vs.":[97,102,105,108,112,140],"score":[99,148],"was":[100],"(0.784":[101],"0.701),":[103],"(0.771":[104],"0.709),":[106],"(0.789":[107],"0.712)":[109],"(0.816":[111],"0.729)":[113],"(p":[114],"<":[115],"0.0001":[116],"all),":[118],"respectively.":[119],"characteristics,":[122],"number,":[124],"location,":[125],"density,":[126],"plus":[127],"number":[128],"vessels,":[130],"significantly":[131,144],"improved":[132,145],"CHD":[133],"prediction":[134],"1-100":[138],"cohort":[139],"Score.":[142],"all":[151],"events.":[153]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":2}],"updated_date":"2026-05-08T15:41:06.802602","created_date":"2025-10-10T00:00:00"}