{"id":"https://openalex.org/W4323310554","doi":"https://doi.org/10.1038/s41746-023-00778-y","title":"Wearable device and smartphone data quantify ALS progression and may provide novel outcome measures","display_name":"Wearable device and smartphone data quantify ALS progression and may provide novel outcome measures","publication_year":2023,"publication_date":"2023-03-06","ids":{"openalex":"https://openalex.org/W4323310554","doi":"https://doi.org/10.1038/s41746-023-00778-y","pmid":"https://pubmed.ncbi.nlm.nih.gov/36879025"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-023-00778-y","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-023-00778-y","pdf_url":"https://www.nature.com/articles/s41746-023-00778-y.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-023-00778-y.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055768833","display_name":"Stephen A. Johnson","orcid":"https://orcid.org/0000-0002-9058-4331"},"institutions":[{"id":"https://openalex.org/I4210125099","display_name":"Mayo Clinic in Arizona","ror":"https://ror.org/03jp40720","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210125099"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stephen A. Johnson","raw_affiliation_strings":["Mayo Clinic, Department of Neurology, Scottsdale, AZ, USA. johnson.stephen2@mayo.edu","Mayo Clinic, Department of Neurology, Scottsdale, AZ, USA"],"raw_orcid":"https://orcid.org/0000-0002-9058-4331","affiliations":[{"raw_affiliation_string":"Mayo Clinic, Department of Neurology, Scottsdale, AZ, USA. johnson.stephen2@mayo.edu","institution_ids":["https://openalex.org/I4210125099"]},{"raw_affiliation_string":"Mayo Clinic, Department of Neurology, Scottsdale, AZ, USA","institution_ids":["https://openalex.org/I4210125099"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030351053","display_name":"Marta Karas","orcid":"https://orcid.org/0000-0001-5889-3970"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marta Karas","raw_affiliation_strings":["Harvard T.H. Chan School of Public Health, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0001-5889-3970","affiliations":[{"raw_affiliation_string":"Harvard T.H. Chan School of Public Health, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062824496","display_name":"Katherine M. Burke","orcid":"https://orcid.org/0000-0002-5820-5880"},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210088741","display_name":"Clinical Research Institute","ror":"https://ror.org/009ywjj88","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210088741"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katherine M. Burke","raw_affiliation_strings":["Neurological Clinical Research Institute and Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-5820-5880","affiliations":[{"raw_affiliation_string":"Neurological Clinical Research Institute and Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210088741","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035104412","display_name":"Marcin Str\u0105czkiewicz","orcid":"https://orcid.org/0000-0002-8703-4451"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marcin Straczkiewicz","raw_affiliation_strings":["Harvard T.H. Chan School of Public Health, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0002-8703-4451","affiliations":[{"raw_affiliation_string":"Harvard T.H. Chan School of Public Health, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042186248","display_name":"Zoe A. Scheier","orcid":"https://orcid.org/0000-0003-1250-9368"},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210088741","display_name":"Clinical Research Institute","ror":"https://ror.org/009ywjj88","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210088741"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zoe A. Scheier","raw_affiliation_strings":["Neurological Clinical Research Institute and Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0003-1250-9368","affiliations":[{"raw_affiliation_string":"Neurological Clinical Research Institute and Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210088741","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042621132","display_name":"Alison Clark","orcid":null},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210088741","display_name":"Clinical Research Institute","ror":"https://ror.org/009ywjj88","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210088741"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alison P. Clark","raw_affiliation_strings":["Neurological Clinical Research Institute and Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurological Clinical Research Institute and Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210088741","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085528603","display_name":"Satoshi Iwasaki","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Satoshi Iwasaki","raw_affiliation_strings":["Mitsubishi Tanabe Pharma Holdings America, Inc, Jersey City, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mitsubishi Tanabe Pharma Holdings America, Inc, Jersey City, NJ, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008811655","display_name":"Amir Lahav","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Amir Lahav","raw_affiliation_strings":["Mitsubishi Tanabe Pharma Holdings America, Inc, Jersey City, NJ, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mitsubishi Tanabe Pharma Holdings America, Inc, Jersey City, NJ, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041287297","display_name":"Amrita Iyer","orcid":null},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210088741","display_name":"Clinical Research Institute","ror":"https://ror.org/009ywjj88","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210088741"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amrita S. Iyer","raw_affiliation_strings":["Neurological Clinical Research Institute and Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurological Clinical Research Institute and Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210088741","https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041695925","display_name":"Jukka\u2010Pekka Onnela","orcid":"https://orcid.org/0000-0001-6613-8668"},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jukka-Pekka Onnela","raw_affiliation_strings":["Harvard T.H. Chan School of Public Health, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Harvard T.H. Chan School of Public Health, Boston, MA, USA","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036652104","display_name":"James D. Berry","orcid":"https://orcid.org/0000-0003-0898-6081"},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I4210088741","display_name":"Clinical Research Institute","ror":"https://ror.org/009ywjj88","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210088741"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James D. Berry","raw_affiliation_strings":["Neurological Clinical Research Institute and Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0003-0898-6081","affiliations":[{"raw_affiliation_string":"Neurological Clinical Research Institute and Sean M. Healey & AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210088741","https://openalex.org/I4210087915"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5055768833"],"corresponding_institution_ids":["https://openalex.org/I4210125099"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":9.6259,"has_fulltext":true,"cited_by_count":48,"citation_normalized_percentile":{"value":0.98584704,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"6","issue":"1","first_page":"34","last_page":"34"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12400","display_name":"Neurogenetic and Muscular Disorders Research","score":0.9467999935150146,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rasch-model","display_name":"Rasch model","score":0.6259337067604065},{"id":"https://openalex.org/keywords/rating-scale","display_name":"Rating scale","score":0.604305624961853},{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"Amyotrophic lateral sclerosis","score":0.5806028842926025},{"id":"https://openalex.org/keywords/wearable-computer","display_name":"Wearable computer","score":0.5537885427474976},{"id":"https://openalex.org/keywords/physical-medicine-and-rehabilitation","display_name":"Physical medicine and rehabilitation","score":0.5451197028160095},{"id":"https://openalex.org/keywords/data-collection","display_name":"Data collection","score":0.5288276076316833},{"id":"https://openalex.org/keywords/activities-of-daily-living","display_name":"Activities of daily living","score":0.471027672290802},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.44408443570137024},{"id":"https://openalex.org/keywords/physical-therapy","display_name":"Physical therapy","score":0.42060983180999756},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.3240126967430115},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3140910267829895},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.16285118460655212},{"id":"https://openalex.org/keywords/embedded-system","display_name":"Embedded system","score":0.1122046411037445}],"concepts":[{"id":"https://openalex.org/C101266164","wikidata":"https://www.wikidata.org/wiki/Q2131821","display_name":"Rasch model","level":2,"score":0.6259337067604065},{"id":"https://openalex.org/C83849319","wikidata":"https://www.wikidata.org/wiki/Q7295720","display_name":"Rating scale","level":2,"score":0.604305624961853},{"id":"https://openalex.org/C2780596555","wikidata":"https://www.wikidata.org/wiki/Q206901","display_name":"Amyotrophic lateral sclerosis","level":3,"score":0.5806028842926025},{"id":"https://openalex.org/C150594956","wikidata":"https://www.wikidata.org/wiki/Q1334829","display_name":"Wearable computer","level":2,"score":0.5537885427474976},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.5451197028160095},{"id":"https://openalex.org/C133462117","wikidata":"https://www.wikidata.org/wiki/Q4929239","display_name":"Data collection","level":2,"score":0.5288276076316833},{"id":"https://openalex.org/C79544238","wikidata":"https://www.wikidata.org/wiki/Q423243","display_name":"Activities of daily living","level":2,"score":0.471027672290802},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44408443570137024},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.42060983180999756},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3240126967430115},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3140910267829895},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.16285118460655212},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.1122046411037445},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-023-00778-y","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-023-00778-y","pdf_url":"https://www.nature.com/articles/s41746-023-00778-y.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:36879025","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36879025","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:9987377","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9987377","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC9987377/pdf/41746_2023_Article_778.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:02887f47e22d43be9f4f4f7017ac6466","is_oa":true,"landing_page_url":"https://doaj.org/article/02887f47e22d43be9f4f4f7017ac6466","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 6, Iss 1, Pp 1-10 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41746-023-00778-y","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-023-00778-y","pdf_url":"https://www.nature.com/articles/s41746-023-00778-y.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306232","display_name":"ALS Association","ror":"https://ror.org/00mwp5989"},{"id":"https://openalex.org/F4320327566","display_name":"Mitsubishi Tanabe Pharma Corporation","ror":"https://ror.org/038ehsm73"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4323310554.pdf"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W1964177214","https://openalex.org/W1978158409","https://openalex.org/W2019655958","https://openalex.org/W2020279151","https://openalex.org/W2026980091","https://openalex.org/W2031638761","https://openalex.org/W2060444352","https://openalex.org/W2074076764","https://openalex.org/W2108381339","https://openalex.org/W2120336810","https://openalex.org/W2120449849","https://openalex.org/W2124951474","https://openalex.org/W2139560421","https://openalex.org/W2142064395","https://openalex.org/W2161938104","https://openalex.org/W2202842799","https://openalex.org/W2279300874","https://openalex.org/W2319548482","https://openalex.org/W2329483624","https://openalex.org/W2593921287","https://openalex.org/W2616124858","https://openalex.org/W2621292042","https://openalex.org/W2752316606","https://openalex.org/W2796393639","https://openalex.org/W2889263571","https://openalex.org/W2905538201","https://openalex.org/W2928494154","https://openalex.org/W2951697757","https://openalex.org/W2975072425","https://openalex.org/W2976945409","https://openalex.org/W2991360048","https://openalex.org/W2998055001","https://openalex.org/W3010508592","https://openalex.org/W3015372504","https://openalex.org/W3024769299","https://openalex.org/W3026401112","https://openalex.org/W3032946898","https://openalex.org/W3043096756","https://openalex.org/W3048923369","https://openalex.org/W3081121745","https://openalex.org/W3082122716","https://openalex.org/W3095995605","https://openalex.org/W3097060684","https://openalex.org/W3110175868","https://openalex.org/W3115439136","https://openalex.org/W3127377019","https://openalex.org/W3136226618","https://openalex.org/W3181959214","https://openalex.org/W3194791349","https://openalex.org/W3204546967","https://openalex.org/W4200567269","https://openalex.org/W4210743933","https://openalex.org/W4220676470","https://openalex.org/W4220833172","https://openalex.org/W4223999556","https://openalex.org/W4226055277","https://openalex.org/W4229079125","https://openalex.org/W4285393688","https://openalex.org/W4288535515"],"related_works":["https://openalex.org/W3120506548","https://openalex.org/W3206395481","https://openalex.org/W2590918987","https://openalex.org/W3007856887","https://openalex.org/W1958255983","https://openalex.org/W57193340","https://openalex.org/W1530834522","https://openalex.org/W2137150530","https://openalex.org/W4387877515","https://openalex.org/W2423146792"],"abstract_inverted_index":{"Amyotrophic":[0],"lateral":[1],"sclerosis":[2],"(ALS)":[3],"therapeutic":[4],"development":[5],"has":[6],"largely":[7],"relied":[8],"on":[9],"staff-administered":[10],"functional":[11,64],"rating":[12,65],"scales":[13],"to":[14,20,32,59],"determine":[15,21],"treatment":[16],"efficacy.":[17],"We":[18],"sought":[19],"if":[22],"mobile":[23],"applications":[24],"(apps)":[25],"and":[26,40,68,101,125,129,132],"wearable":[27,113],"devices":[28],"can":[29],"be":[30],"used":[31,58,82],"quantify":[33],"ALS":[34,49,63,72,141],"disease":[35],"progression":[36],"through":[37],"active":[38],"(surveys)":[39],"passive":[41,133],"(sensors)":[42],"data":[43,114,135],"collection.":[44],"Forty":[45],"ambulatory":[46],"adults":[47],"with":[48,110,127],"were":[50,105],"followed":[51],"for":[52,139],"6-months.":[53],"The":[54],"Beiwe":[55],"app":[56,102],"was":[57],"administer":[60],"the":[61,69],"self-entry":[62],"scale-revised":[66],"(ALSFRS-RSE)":[67],"Rasch":[70],"Overall":[71],"Disability":[73],"Scale":[74],"(ROADS)":[75],"surveys":[76],"every":[77],"2-4":[78],"weeks.":[79],"Each":[80],"participant":[81],"a":[83],"wrist-worn":[84],"activity":[85,93,117],"monitor":[86,94],"(ActiGraph":[87],"Insight":[88],"Watch)":[89],"or":[90],"an":[91],"ankle-worn":[92],"(Modus":[95],"StepWatch)":[96],"continuously.":[97],"Wearable":[98],"device":[99],"wear":[100],"survey":[103],"compliance":[104],"adequate.":[106],"ALSFRS-R":[107],"highly":[108],"correlated":[109],"ALSFRS-RSE.":[111],"Several":[112],"daily":[115],"physical":[116],"measures":[118],"demonstrated":[119],"statistically":[120],"significant":[121],"change":[122],"over":[123],"time":[124],"associations":[126],"ALSFRS-RSE":[128],"ROADS.":[130],"Active":[131],"digital":[134],"collection":[136],"hold":[137],"promise":[138],"novel":[140],"trial":[142],"outcome":[143],"measure":[144],"development.":[145]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":16},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":3}],"updated_date":"2026-02-03T23:48:18.283914","created_date":"2025-10-10T00:00:00"}