{"id":"https://openalex.org/W3207000571","doi":"https://doi.org/10.1038/s41746-021-00522-4","title":"Optimizing drug selection from a prescription trajectory of one patient","display_name":"Optimizing drug selection from a prescription trajectory of one patient","publication_year":2021,"publication_date":"2021-10-20","ids":{"openalex":"https://openalex.org/W3207000571","doi":"https://doi.org/10.1038/s41746-021-00522-4","mag":"3207000571","pmid":"https://pubmed.ncbi.nlm.nih.gov/34671068"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-021-00522-4","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-021-00522-4","pdf_url":"https://www.nature.com/articles/s41746-021-00522-4.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-021-00522-4.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043842473","display_name":"Alejandro Aguayo\u2010Orozco","orcid":"https://orcid.org/0000-0003-1828-223X"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1320355602","display_name":"Statistics Denmark","ror":"https://ror.org/000f7jy90","country_code":"DK","type":"government","lineage":["https://openalex.org/I1320355602"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]}],"countries":["DK"],"is_corresponding":true,"raw_author_name":"Alejandro Aguayo-Orozco","raw_affiliation_strings":["Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark","Statistics Denmark, 2100, Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0003-1828-223X","affiliations":[{"raw_affiliation_string":"Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2801134892","https://openalex.org/I124055696"]},{"raw_affiliation_string":"Statistics Denmark, 2100, Copenhagen, Denmark","institution_ids":["https://openalex.org/I1320355602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040162100","display_name":"Amalie Dahl Haue","orcid":"https://orcid.org/0000-0001-7656-7976"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]},{"id":"https://openalex.org/I2802567020","display_name":"Copenhagen University Hospital","ror":"https://ror.org/05bpbnx46","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Amalie Dahl Haue","raw_affiliation_strings":["Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark","The Heart Center, Righospitalet, Copenhagen University Hospital, Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0001-7656-7976","affiliations":[{"raw_affiliation_string":"Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2801134892","https://openalex.org/I124055696"]},{"raw_affiliation_string":"The Heart Center, Righospitalet, Copenhagen University Hospital, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2802567020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073867964","display_name":"Isabella Friis J\u00f8rgensen","orcid":"https://orcid.org/0000-0001-5694-4332"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Isabella Friis J\u00f8rgensen","raw_affiliation_strings":["Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0001-5694-4332","affiliations":[{"raw_affiliation_string":"Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2801134892","https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014841854","display_name":"David Westergaard","orcid":"https://orcid.org/0000-0003-0128-8432"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1320355602","display_name":"Statistics Denmark","ror":"https://ror.org/000f7jy90","country_code":"DK","type":"government","lineage":["https://openalex.org/I1320355602"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]},{"id":"https://openalex.org/I2801942218","display_name":"Hvidovre Hospital","ror":"https://ror.org/00edrn755","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801942218","https://openalex.org/I2802567020"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"David Westergaard","raw_affiliation_strings":["Department of Obstetrics and Gynaecology, Amager Hvidovre Hospital, Copenhagen University Hospital, Hvidovre, Denmark","Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark","Statistics Denmark, 2100, Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0003-0128-8432","affiliations":[{"raw_affiliation_string":"Department of Obstetrics and Gynaecology, Amager Hvidovre Hospital, Copenhagen University Hospital, Hvidovre, Denmark","institution_ids":["https://openalex.org/I2801942218"]},{"raw_affiliation_string":"Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2801134892","https://openalex.org/I124055696"]},{"raw_affiliation_string":"Statistics Denmark, 2100, Copenhagen, Denmark","institution_ids":["https://openalex.org/I1320355602"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053705167","display_name":"Pope Moseley","orcid":"https://orcid.org/0000-0002-3723-9950"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Pope Lloyd Moseley","raw_affiliation_strings":["Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2801134892","https://openalex.org/I124055696"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007825736","display_name":"Laust Hvas Mortensen","orcid":"https://orcid.org/0000-0002-6399-495X"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I1320355602","display_name":"Statistics Denmark","ror":"https://ror.org/000f7jy90","country_code":"DK","type":"government","lineage":["https://openalex.org/I1320355602"]},{"id":"https://openalex.org/I4210140904","display_name":"DK4","ror":"https://ror.org/041xgzk22","country_code":"DK","type":"other","lineage":["https://openalex.org/I4210140904"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Laust Hvas Mortensen","raw_affiliation_strings":["Section of Epidemiology, Department of Public Health, University of Copenhagen, 1014, Copenhagen, Denmark. lhm@dst.dk","Statistics Denmark, 2100, Copenhagen, Denmark. lhm@dst.dk","Statistics Denmark, 2100, Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-6399-495X","affiliations":[{"raw_affiliation_string":"Section of Epidemiology, Department of Public Health, University of Copenhagen, 1014, Copenhagen, Denmark. lhm@dst.dk","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Statistics Denmark, 2100, Copenhagen, Denmark. lhm@dst.dk","institution_ids":["https://openalex.org/I1320355602","https://openalex.org/I4210140904"]},{"raw_affiliation_string":"Statistics Denmark, 2100, Copenhagen, Denmark","institution_ids":["https://openalex.org/I1320355602"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011862057","display_name":"S\u00f8ren Brunak","orcid":"https://orcid.org/0000-0003-0316-5866"},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801134892","display_name":"Novo Nordisk Foundation","ror":"https://ror.org/04txyc737","country_code":"DK","type":"facility","lineage":["https://openalex.org/I2801134892"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"S\u00f8ren Brunak","raw_affiliation_strings":["Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark. soren.brunak@cpr.ku.dk","Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark"],"raw_orcid":"https://orcid.org/0000-0003-0316-5866","affiliations":[{"raw_affiliation_string":"Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark. soren.brunak@cpr.ku.dk","institution_ids":["https://openalex.org/I2801134892"]},{"raw_affiliation_string":"Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark","institution_ids":["https://openalex.org/I2801134892","https://openalex.org/I124055696"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5043842473"],"corresponding_institution_ids":["https://openalex.org/I124055696","https://openalex.org/I1320355602","https://openalex.org/I2801134892"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":1.6792,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.87193664,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"4","issue":"1","first_page":"150","last_page":"150"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9886999726295471,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9886999726295471,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":0.9876999855041504,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11235","display_name":"Statistical Methods in Clinical Trials","score":0.9836000204086304,"subfield":{"id":"https://openalex.org/subfields/2613","display_name":"Statistics and Probability"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.7113227844238281},{"id":"https://openalex.org/keywords/medical-prescription","display_name":"Medical prescription","score":0.6845536231994629},{"id":"https://openalex.org/keywords/trajectory","display_name":"Trajectory","score":0.5920464396476746},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.5124979019165039},{"id":"https://openalex.org/keywords/prescription-drug","display_name":"Prescription drug","score":0.4487890899181366},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3835754692554474},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.32244163751602173},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.24972322583198547},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.20570337772369385}],"concepts":[{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.7113227844238281},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.6845536231994629},{"id":"https://openalex.org/C13662910","wikidata":"https://www.wikidata.org/wiki/Q193139","display_name":"Trajectory","level":2,"score":0.5920464396476746},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.5124979019165039},{"id":"https://openalex.org/C2778858636","wikidata":"https://www.wikidata.org/wiki/Q1643563","display_name":"Prescription drug","level":3,"score":0.4487890899181366},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3835754692554474},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32244163751602173},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.24972322583198547},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.20570337772369385},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1038/s41746-021-00522-4","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-021-00522-4","pdf_url":"https://www.nature.com/articles/s41746-021-00522-4.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:34671068","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34671068","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:8839a24dd7514a03bbb3657b5b26b26d","is_oa":true,"landing_page_url":"https://doaj.org/article/8839a24dd7514a03bbb3657b5b26b26d","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 4, Iss 1, Pp 1-9 (2021)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:8528868","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8528868","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/271e0cba-eafe-42f6-bac5-3d4b05f06590","is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/271e0cba-eafe-42f6-bac5-3d4b05f06590","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Aguayo-Orozco , A , Haue , A D , J\u00f8rgensen , I F , Westergaard , D , Moseley , P L , Mortensen , L H & Brunak , S 2021 , ' Optimizing drug selection from a prescription trajectory of one patient ' , npj Digital Medicine , vol. 4 , no. 1 , 150 . https://doi.org/10.1038/s41746-021-00522-4","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41746-021-00522-4","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-021-00522-4","pdf_url":"https://www.nature.com/articles/s41746-021-00522-4.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8199999928474426}],"awards":[{"id":"https://openalex.org/G143460415","display_name":null,"funder_award_id":"NNF17OC0027594","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"},{"id":"https://openalex.org/G5850737185","display_name":null,"funder_award_id":"MC_PC_17228","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G6662978750","display_name":null,"funder_award_id":"NNF14CC0001","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"},{"id":"https://openalex.org/G7548833942","display_name":null,"funder_award_id":"NNF18SA0034956","funder_id":"https://openalex.org/F4320325957","funder_display_name":"Novo Nordisk Fonden"}],"funders":[{"id":"https://openalex.org/F4320325957","display_name":"Novo Nordisk Fonden","ror":"https://ror.org/04txyc737"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3207000571.pdf","grobid_xml":"https://content.openalex.org/works/W3207000571.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W2000445173","https://openalex.org/W2004666175","https://openalex.org/W2004910511","https://openalex.org/W2006183964","https://openalex.org/W2014112647","https://openalex.org/W2021927168","https://openalex.org/W2086632167","https://openalex.org/W2102354326","https://openalex.org/W2102420102","https://openalex.org/W2116224448","https://openalex.org/W2142749836","https://openalex.org/W2273960279","https://openalex.org/W2337789656","https://openalex.org/W2342090630","https://openalex.org/W2480651174","https://openalex.org/W2487757292","https://openalex.org/W2514333907","https://openalex.org/W2724998565","https://openalex.org/W2770922872","https://openalex.org/W2886805531","https://openalex.org/W2928514684","https://openalex.org/W2945850853","https://openalex.org/W2948946498","https://openalex.org/W2951096737","https://openalex.org/W2956091366","https://openalex.org/W2964739309","https://openalex.org/W2966515167","https://openalex.org/W2973359600","https://openalex.org/W2980487785","https://openalex.org/W3020023509","https://openalex.org/W3021406499","https://openalex.org/W3023529892","https://openalex.org/W3048611576","https://openalex.org/W3090765916","https://openalex.org/W3123319961","https://openalex.org/W3149026346","https://openalex.org/W4249344264","https://openalex.org/W4300823542","https://openalex.org/W6675366009","https://openalex.org/W6703362761","https://openalex.org/W6746008930"],"related_works":["https://openalex.org/W2361820086","https://openalex.org/W4388487825","https://openalex.org/W2368224867","https://openalex.org/W3029903131","https://openalex.org/W3111030087","https://openalex.org/W2341334583","https://openalex.org/W2385685139","https://openalex.org/W3151315576","https://openalex.org/W1960377041","https://openalex.org/W2413810328"],"abstract_inverted_index":{").":[0],"Replication":[1],"in":[2],"UK":[3],"Biobank":[4],"data":[5],"showed":[6],"the":[7],"same":[8],"trends.":[9],"Prescription":[10],"trajectories":[11],"can":[12],"provide":[13],"novel":[14],"insights":[15],"into":[16],"how":[17],"individuals'":[18],"drug":[19],"use":[20],"change":[21],"over":[22],"time,":[23],"identify":[24],"suboptimal":[25],"or":[26],"futile":[27],"prescriptions":[28],"and":[29],"suggest":[30],"initial":[31],"treatments":[32],"different":[33],"from":[34],"first":[35],"line":[36],"therapies.":[37],"Observations":[38],"of":[39],"this":[40],"kind":[41],"may":[42],"also":[43],"be":[44],"important":[45],"when":[46],"updating":[47],"treatment":[48],"guidelines.":[49]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3}],"updated_date":"2026-05-06T08:25:59.206177","created_date":"2025-10-10T00:00:00"}
