{"id":"https://openalex.org/W2995028672","doi":"https://doi.org/10.1038/s41746-019-0203-0","title":"Digital clinical trials: creating a vision for the future","display_name":"Digital clinical trials: creating a vision for the future","publication_year":2019,"publication_date":"2019-12-12","ids":{"openalex":"https://openalex.org/W2995028672","doi":"https://doi.org/10.1038/s41746-019-0203-0","mag":"2995028672","pmid":"https://pubmed.ncbi.nlm.nih.gov/31872066"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-019-0203-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0203-0","pdf_url":"https://www.nature.com/articles/s41746-019-0203-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"editorial","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-019-0203-0.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054364960","display_name":"Steven R. Steinhubl","orcid":null},"institutions":[{"id":"https://openalex.org/I123431417","display_name":"Scripps Research Institute","ror":"https://ror.org/02dxx6824","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I123431417"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Steven R. Steinhubl","raw_affiliation_strings":["Scripps Research Translational Institute & Wave Research Center, LaJolla, CA USA","Scripps Research Translational Institute & Wave Research Center, LaJolla, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-9256-7914","affiliations":[{"raw_affiliation_string":"Scripps Research Translational Institute & Wave Research Center, LaJolla, CA USA","institution_ids":["https://openalex.org/I123431417"]},{"raw_affiliation_string":"Scripps Research Translational Institute & Wave Research Center, LaJolla, CA, USA","institution_ids":["https://openalex.org/I123431417"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004653416","display_name":"Dana L. Wolff\u2010Hughes","orcid":"https://orcid.org/0000-0003-3280-9771"},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210091794","display_name":"Office of the Director","ror":"https://ror.org/00fj8a872","country_code":"US","type":"other","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210091794"]},{"id":"https://openalex.org/I4210158265","display_name":"Applied Behavioral Research (United States)","ror":"https://ror.org/0290kkw06","country_code":"US","type":"company","lineage":["https://openalex.org/I4210158265"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dana L. Wolff-Hughes","raw_affiliation_strings":["National Institutes of Health, Office of Behavioral and Social Sciences Research, Bethesda, MD USA","National Institutes of Health, Office of Behavioral and Social Sciences Research, Bethesda, MD, USA"],"raw_orcid":"https://orcid.org/0000-0003-3280-9771","affiliations":[{"raw_affiliation_string":"National Institutes of Health, Office of Behavioral and Social Sciences Research, Bethesda, MD USA","institution_ids":["https://openalex.org/I4210091794","https://openalex.org/I4210158265"]},{"raw_affiliation_string":"National Institutes of Health, Office of Behavioral and Social Sciences Research, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041974884","display_name":"Wendy Nilsen","orcid":"https://orcid.org/0000-0002-2982-0673"},"institutions":[{"id":"https://openalex.org/I1311060795","display_name":"U.S. National Science Foundation","ror":"https://ror.org/021nxhr62","country_code":"US","type":"government","lineage":["https://openalex.org/I1311060795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wendy Nilsen","raw_affiliation_strings":["National Science Foundation, Computer and Information Science and Engineering, Alexandria, VA USA","National Science Foundation, Computer and Information Science and Engineering, Alexandria, VA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Science Foundation, Computer and Information Science and Engineering, Alexandria, VA USA","institution_ids":["https://openalex.org/I1311060795"]},{"raw_affiliation_string":"National Science Foundation, Computer and Information Science and Engineering, Alexandria, VA, USA","institution_ids":["https://openalex.org/I1311060795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009413704","display_name":"Erin Iturriaga","orcid":"https://orcid.org/0000-0002-1032-1428"},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart Lung and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erin Iturriaga","raw_affiliation_strings":["4National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, MD USA","National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, MD USA","institution_ids":["https://openalex.org/I4210106489"]},{"raw_affiliation_string":"National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, MD, USA","institution_ids":["https://openalex.org/I4210106489","https://openalex.org/I1299303238"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5060829829","display_name":"Robert M. Califf","orcid":"https://orcid.org/0000-0003-0231-3724"},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210128969","display_name":"Alphabet (United States)","ror":"https://ror.org/02e9yx751","country_code":"US","type":"company","lineage":["https://openalex.org/I4210128969"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert M. Califf","raw_affiliation_strings":["5Verily Life Sciences, Alphabet Inc, South San Francisco, California, USA and Duke Forge, Duke University School of Medicine, Durham, NC USA","Verily Life Sciences, Alphabet Inc, South San Francisco, California, USA and Duke Forge, Duke University School of Medicine, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5Verily Life Sciences, Alphabet Inc, South San Francisco, California, USA and Duke Forge, Duke University School of Medicine, Durham, NC USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Verily Life Sciences, Alphabet Inc, South San Francisco, California, USA and Duke Forge, Duke University School of Medicine, Durham, NC, USA","institution_ids":["https://openalex.org/I4210128969","https://openalex.org/I170897317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5054364960"],"corresponding_institution_ids":["https://openalex.org/I123431417"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":4.5858,"has_fulltext":true,"cited_by_count":75,"citation_normalized_percentile":{"value":0.95483249,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"2","issue":"1","first_page":"126","last_page":"126"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13280","display_name":"Biomedical and Engineering Education","score":0.9940000176429749,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13280","display_name":"Biomedical and Engineering Education","score":0.9940000176429749,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10582","display_name":"Ethics in Clinical Research","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/optometry","display_name":"Optometry","score":0.3831852078437805},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.38236212730407715},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.32646751403808594},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.28029727935791016}],"concepts":[{"id":"https://openalex.org/C119767625","wikidata":"https://www.wikidata.org/wiki/Q618211","display_name":"Optometry","level":1,"score":0.3831852078437805},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.38236212730407715},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.32646751403808594},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.28029727935791016}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1038/s41746-019-0203-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0203-0","pdf_url":"https://www.nature.com/articles/s41746-019-0203-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:31872066","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31872066","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:e716bcbc8a7e46a1a9f41a6013848baf","is_oa":true,"landing_page_url":"https://doaj.org/article/e716bcbc8a7e46a1a9f41a6013848baf","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 2, Iss 1, Pp 1-3 (2019)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:5876801","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6908600","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-019-0203-0","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0203-0","pdf_url":"https://www.nature.com/articles/s41746-019-0203-0.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2995028672.pdf","grobid_xml":"https://content.openalex.org/works/W2995028672.grobid-xml"},"referenced_works_count":12,"referenced_works":["https://openalex.org/W1562444029","https://openalex.org/W2074048861","https://openalex.org/W2126607392","https://openalex.org/W2219329093","https://openalex.org/W2883478711","https://openalex.org/W2890763753","https://openalex.org/W2896442240","https://openalex.org/W2897034645","https://openalex.org/W2917431061","https://openalex.org/W2921176698","https://openalex.org/W2922933079","https://openalex.org/W2963160463"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W2382290278","https://openalex.org/W2478288626","https://openalex.org/W2350741829","https://openalex.org/W2530322880","https://openalex.org/W1596801655"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":17},{"year":2020,"cited_by_count":13}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2019-12-26T00:00:00"}