{"id":"https://openalex.org/W2969628488","doi":"https://doi.org/10.1038/s41746-019-0158-1","title":"Why digital medicine depends on interoperability","display_name":"Why digital medicine depends on interoperability","publication_year":2019,"publication_date":"2019-08-20","ids":{"openalex":"https://openalex.org/W2969628488","doi":"https://doi.org/10.1038/s41746-019-0158-1","mag":"2969628488","pmid":"https://pubmed.ncbi.nlm.nih.gov/31453374"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-019-0158-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0158-1","pdf_url":"https://www.nature.com/articles/s41746-019-0158-1.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-019-0158-1.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017810472","display_name":"Moritz Lehne","orcid":"https://orcid.org/0000-0001-8435-1374"},"institutions":[{"id":"https://openalex.org/I4210139777","display_name":"Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/0493xsw21","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Moritz Lehne","raw_affiliation_strings":["1Berlin Institute of Health (BIH), Berlin, Germany","Berlin Institute of Health (BIH), Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0001-8435-1374","affiliations":[{"raw_affiliation_string":"1Berlin Institute of Health (BIH), Berlin, Germany","institution_ids":["https://openalex.org/I4210139777"]},{"raw_affiliation_string":"Berlin Institute of Health (BIH), Berlin, Germany","institution_ids":["https://openalex.org/I4210139777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029283368","display_name":"Julian Sa\u00df","orcid":"https://orcid.org/0000-0002-2068-7765"},"institutions":[{"id":"https://openalex.org/I4210139777","display_name":"Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/0493xsw21","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Julian Sass","raw_affiliation_strings":["1Berlin Institute of Health (BIH), Berlin, Germany","Berlin Institute of Health (BIH), Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0002-2068-7765","affiliations":[{"raw_affiliation_string":"1Berlin Institute of Health (BIH), Berlin, Germany","institution_ids":["https://openalex.org/I4210139777"]},{"raw_affiliation_string":"Berlin Institute of Health (BIH), Berlin, Germany","institution_ids":["https://openalex.org/I4210139777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075396284","display_name":"Andrea Essenwanger","orcid":"https://orcid.org/0000-0002-0042-8088"},"institutions":[{"id":"https://openalex.org/I4210139777","display_name":"Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/0493xsw21","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andrea Essenwanger","raw_affiliation_strings":["1Berlin Institute of Health (BIH), Berlin, Germany","Berlin Institute of Health (BIH), Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0002-0042-8088","affiliations":[{"raw_affiliation_string":"1Berlin Institute of Health (BIH), Berlin, Germany","institution_ids":["https://openalex.org/I4210139777"]},{"raw_affiliation_string":"Berlin Institute of Health (BIH), Berlin, Germany","institution_ids":["https://openalex.org/I4210139777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055416334","display_name":"Josef Schepers","orcid":"https://orcid.org/0000-0001-7350-2480"},"institutions":[{"id":"https://openalex.org/I4210139777","display_name":"Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/0493xsw21","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Josef Schepers","raw_affiliation_strings":["1Berlin Institute of Health (BIH), Berlin, Germany","Berlin Institute of Health (BIH), Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0001-7350-2480","affiliations":[{"raw_affiliation_string":"1Berlin Institute of Health (BIH), Berlin, Germany","institution_ids":["https://openalex.org/I4210139777"]},{"raw_affiliation_string":"Berlin Institute of Health (BIH), Berlin, Germany","institution_ids":["https://openalex.org/I4210139777"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045196355","display_name":"Sylvia Thun","orcid":"https://orcid.org/0000-0002-3346-6806"},"institutions":[{"id":"https://openalex.org/I4210113269","display_name":"Hochschule Niederrhein","ror":"https://ror.org/027b9qx26","country_code":"DE","type":"education","lineage":["https://openalex.org/I4210113269"]},{"id":"https://openalex.org/I4210139777","display_name":"Berlin Institute of Health at Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/0493xsw21","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210139777","https://openalex.org/I7877124"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 - Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sylvia Thun","raw_affiliation_strings":["1Berlin Institute of Health (BIH), Berlin, Germany","2Charit\u00e9 - Universit\u00e4tsmedizin Berlin, Berlin, Germany","3Hochschule Niederrhein - University of Applied Sciences, Krefeld, Germany","Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Berlin Institute of Health (BIH), Berlin, Germany","institution_ids":["https://openalex.org/I4210139777"]},{"raw_affiliation_string":"2Charit\u00e9 - Universit\u00e4tsmedizin Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]},{"raw_affiliation_string":"3Hochschule Niederrhein - University of Applied Sciences, Krefeld, Germany","institution_ids":["https://openalex.org/I4210113269"]},{"raw_affiliation_string":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Berlin, Germany","institution_ids":["https://openalex.org/I7877124"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5017810472"],"corresponding_institution_ids":["https://openalex.org/I4210139777"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":1053,"currency":"EUR","value_usd":1135},"fwci":11.86,"has_fulltext":true,"cited_by_count":464,"citation_normalized_percentile":{"value":0.98237598,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"2","issue":"1","first_page":"79","last_page":"79"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11396","display_name":"Artificial Intelligence in Healthcare","score":0.9782000184059143,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10350","display_name":"Electronic Health Records Systems","score":0.9668999910354614,"subfield":{"id":"https://openalex.org/subfields/3605","display_name":"Health Information Management"},"field":{"id":"https://openalex.org/fields/36","display_name":"Health Professions"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interoperability","display_name":"Interoperability","score":0.9594686627388},{"id":"https://openalex.org/keywords/big-data","display_name":"Big data","score":0.7249347567558289},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.649326741695404},{"id":"https://openalex.org/keywords/cross-domain-interoperability","display_name":"Cross-domain interoperability","score":0.6060518026351929},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.604341447353363},{"id":"https://openalex.org/keywords/digital-transformation","display_name":"Digital transformation","score":0.5799594521522522},{"id":"https://openalex.org/keywords/data-exchange","display_name":"Data exchange","score":0.5496370792388916},{"id":"https://openalex.org/keywords/digital-health","display_name":"Digital health","score":0.4452725350856781},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.4408408999443054},{"id":"https://openalex.org/keywords/semantic-interoperability","display_name":"Semantic interoperability","score":0.43367835879325867},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.38081201910972595},{"id":"https://openalex.org/keywords/health-care","display_name":"Health care","score":0.19085800647735596},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.15385830402374268},{"id":"https://openalex.org/keywords/political-science","display_name":"Political science","score":0.08963173627853394}],"concepts":[{"id":"https://openalex.org/C20136886","wikidata":"https://www.wikidata.org/wiki/Q749647","display_name":"Interoperability","level":2,"score":0.9594686627388},{"id":"https://openalex.org/C75684735","wikidata":"https://www.wikidata.org/wiki/Q858810","display_name":"Big data","level":2,"score":0.7249347567558289},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.649326741695404},{"id":"https://openalex.org/C26805982","wikidata":"https://www.wikidata.org/wiki/Q17008183","display_name":"Cross-domain interoperability","level":4,"score":0.6060518026351929},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.604341447353363},{"id":"https://openalex.org/C126082660","wikidata":"https://www.wikidata.org/wiki/Q4252370","display_name":"Digital transformation","level":2,"score":0.5799594521522522},{"id":"https://openalex.org/C15845906","wikidata":"https://www.wikidata.org/wiki/Q1172338","display_name":"Data exchange","level":2,"score":0.5496370792388916},{"id":"https://openalex.org/C2780433410","wikidata":"https://www.wikidata.org/wiki/Q5276090","display_name":"Digital health","level":3,"score":0.4452725350856781},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.4408408999443054},{"id":"https://openalex.org/C192800085","wikidata":"https://www.wikidata.org/wiki/Q5258530","display_name":"Semantic interoperability","level":3,"score":0.43367835879325867},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.38081201910972595},{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.19085800647735596},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.15385830402374268},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.08963173627853394},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1038/s41746-019-0158-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0158-1","pdf_url":"https://www.nature.com/articles/s41746-019-0158-1.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:31453374","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31453374","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:ff2e1dcebf9d416b984ceb3e9535d5b0","is_oa":true,"landing_page_url":"https://doaj.org/article/ff2e1dcebf9d416b984ceb3e9535d5b0","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 2, Iss 1, Pp 1-5 (2019)","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6702215","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6702215","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"NPJ Digit Med","raw_type":"Text"},{"id":"pmh:oai:refubium.fu-berlin.de:fub188/26441","is_oa":true,"landing_page_url":"https://refubium.fu-berlin.de/handle/fub188/26441","pdf_url":null,"source":{"id":"https://openalex.org/S4306402444","display_name":"Refubium (Universit\u00e4tsbibliothek der Freien Universit\u00e4t Berlin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I75951250","host_organization_name":"Freie Universit\u00e4t Berlin","host_organization_lineage":["https://openalex.org/I75951250"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"doc-type:article"},{"id":"doi:10.17169/refubium-26201","is_oa":true,"landing_page_url":"https://doi.org/10.17169/refubium-26201","pdf_url":null,"source":{"id":"https://openalex.org/S7407052913","display_name":"Universit\u00e4tsbibliothek der FU Berlin Hochschulschriftenstelle u. Dokumentenserver","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1038/s41746-019-0158-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0158-1","pdf_url":"https://www.nature.com/articles/s41746-019-0158-1.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/17","score":0.5600000023841858,"display_name":"Partnerships for the goals"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320321526","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2969628488.pdf","grobid_xml":"https://content.openalex.org/works/W2969628488.grobid-xml"},"referenced_works_count":33,"referenced_works":["https://openalex.org/W111228517","https://openalex.org/W1971192989","https://openalex.org/W1981660199","https://openalex.org/W2004910511","https://openalex.org/W2068163455","https://openalex.org/W2082302018","https://openalex.org/W2110185282","https://openalex.org/W2119611042","https://openalex.org/W2136410628","https://openalex.org/W2164572080","https://openalex.org/W2165748167","https://openalex.org/W2168217134","https://openalex.org/W2276530525","https://openalex.org/W2489651338","https://openalex.org/W2525984666","https://openalex.org/W2527360010","https://openalex.org/W2542446037","https://openalex.org/W2557738935","https://openalex.org/W2563625904","https://openalex.org/W2581082771","https://openalex.org/W2584596997","https://openalex.org/W2664267452","https://openalex.org/W2734746729","https://openalex.org/W2759174152","https://openalex.org/W2763496415","https://openalex.org/W2785526886","https://openalex.org/W2792145227","https://openalex.org/W2799605298","https://openalex.org/W2806008746","https://openalex.org/W2907288920","https://openalex.org/W2911462778","https://openalex.org/W2934399013","https://openalex.org/W4251392746"],"related_works":["https://openalex.org/W2109385585","https://openalex.org/W3209454962","https://openalex.org/W2913525168","https://openalex.org/W4367040610","https://openalex.org/W2621382554","https://openalex.org/W939442210","https://openalex.org/W2294923962","https://openalex.org/W3179006481","https://openalex.org/W3036438062","https://openalex.org/W2885367039"],"abstract_inverted_index":{"Digital":[0],"data":[1,12,25,44,49,86],"are":[2,26,90],"anticipated":[3],"to":[4,28,57,119],"transform":[5],"medicine.":[6,78],"However,":[7],"most":[8],"of":[9,125],"today's":[10],"medical":[11,36,100],"lack":[13],"interoperability:":[14],"hidden":[15],"in":[16,116],"isolated":[17],"databases,":[18],"incompatible":[19],"systems":[20,89],"and":[21,31,87,96,104,123],"proprietary":[22],"software,":[23],"the":[24,72,121],"difficult":[27],"exchange,":[29],"analyze,":[30],"interpret.":[32],"This":[33],"slows":[34],"down":[35],"progress,":[37],"as":[38],"technologies":[39],"that":[40,66],"rely":[41],"on":[42,81],"these":[43,117],"-":[45,53],"artificial":[46,94],"intelligence,":[47],"big":[48,97],"or":[50],"mobile":[51],"applications":[52],"cannot":[54],"be":[55],"used":[56],"their":[58],"full":[59],"potential.":[60],"In":[61],"this":[62],"article,":[63],"we":[64],"argue":[65],"interoperability":[67,111],"is":[68],"a":[69],"prerequisite":[70],"for":[71,76],"digital":[73,114],"innovations":[74],"envisioned":[75],"future":[77],"We":[79,108],"focus":[80],"four":[82],"areas":[83,118],"where":[84],"interoperable":[85],"IT":[88],"particularly":[91],"important:":[92],"(1)":[93],"intelligence":[95],"data;":[98],"(2)":[99],"communication;":[101],"(3)":[102],"research;":[103],"(4)":[105],"international":[106],"cooperation.":[107],"discuss":[109],"how":[110],"can":[112],"facilitate":[113],"transformation":[115],"improve":[120],"health":[122],"well-being":[124],"patients":[126],"worldwide.":[127]},"counts_by_year":[{"year":2026,"cited_by_count":20},{"year":2025,"cited_by_count":93},{"year":2024,"cited_by_count":125},{"year":2023,"cited_by_count":70},{"year":2022,"cited_by_count":61},{"year":2021,"cited_by_count":64},{"year":2020,"cited_by_count":29},{"year":2019,"cited_by_count":1}],"updated_date":"2026-04-25T08:17:42.794288","created_date":"2019-08-29T00:00:00"}