{"id":"https://openalex.org/W2961700348","doi":"https://doi.org/10.1038/s41746-019-0140-y","title":"Precision identification of high-risk phenotypes and progression pathways in severe malaria without requiring longitudinal data","display_name":"Precision identification of high-risk phenotypes and progression pathways in severe malaria without requiring longitudinal data","publication_year":2019,"publication_date":"2019-07-10","ids":{"openalex":"https://openalex.org/W2961700348","doi":"https://doi.org/10.1038/s41746-019-0140-y","mag":"2961700348","pmid":"https://pubmed.ncbi.nlm.nih.gov/31312723"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-019-0140-y","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0140-y","pdf_url":"https://www.nature.com/articles/s41746-019-0140-y.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-019-0140-y.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016846029","display_name":"Iain G. Johnston","orcid":"https://orcid.org/0000-0001-8559-3519"},"institutions":[{"id":"https://openalex.org/I125680101","display_name":"Turing Institute","ror":"https://ror.org/02x2mw849","country_code":"GB","type":"facility","lineage":["https://openalex.org/I125680101"]},{"id":"https://openalex.org/I1299528221","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842","country_code":"GB","type":"government","lineage":["https://openalex.org/I1299528221","https://openalex.org/I4210087105"]},{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I4210128584","display_name":"The Alan Turing Institute","ror":"https://ror.org/035dkdb55","country_code":"GB","type":"facility","lineage":["https://openalex.org/I4210128584"]},{"id":"https://openalex.org/I4432739","display_name":"University of Bergen","ror":"https://ror.org/03zga2b32","country_code":"NO","type":"education","lineage":["https://openalex.org/I4432739"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB","NO"],"is_corresponding":true,"raw_author_name":"Iain G. Johnston","raw_affiliation_strings":["1Faculty of Mathematics and Natural Sciences, University of Bergen, Bergen, Norway","2EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","3Alan Turing Institute, London, UK","Alan Turing Institute, London, UK","Faculty of Mathematics and Natural Sciences, University of Bergen, Bergen, Norway","EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Faculty of Mathematics and Natural Sciences, University of Bergen, Bergen, Norway","institution_ids":["https://openalex.org/I4432739"]},{"raw_affiliation_string":"2EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","institution_ids":["https://openalex.org/I153355300"]},{"raw_affiliation_string":"3Alan Turing Institute, London, UK","institution_ids":["https://openalex.org/I125680101","https://openalex.org/I4210128584"]},{"raw_affiliation_string":"Alan Turing Institute, London, UK","institution_ids":["https://openalex.org/I4210128584"]},{"raw_affiliation_string":"Faculty of Mathematics and Natural Sciences, University of Bergen, Bergen, Norway","institution_ids":["https://openalex.org/I4432739"]},{"raw_affiliation_string":"EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","institution_ids":["https://openalex.org/I1299528221","https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067794169","display_name":"Till Hoffmann","orcid":"https://orcid.org/0000-0003-4403-0722"},"institutions":[{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Till Hoffmann","raw_affiliation_strings":["4Department of Mathematics, Imperial College London, London, UK","Department of Mathematics, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"4Department of Mathematics, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Department of Mathematics, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087754264","display_name":"Sam F. Greenbury","orcid":"https://orcid.org/0000-0003-4452-2006"},"institutions":[{"id":"https://openalex.org/I1299528221","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842","country_code":"GB","type":"government","lineage":["https://openalex.org/I1299528221","https://openalex.org/I4210087105"]},{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Sam F. Greenbury","raw_affiliation_strings":["2EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","4Department of Mathematics, Imperial College London, London, UK","Department of Mathematics, Imperial College London, London, UK","EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK"],"raw_orcid":"https://orcid.org/0000-0003-4452-2006","affiliations":[{"raw_affiliation_string":"2EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","institution_ids":["https://openalex.org/I153355300"]},{"raw_affiliation_string":"4Department of Mathematics, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"Department of Mathematics, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","institution_ids":["https://openalex.org/I1299528221","https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048790165","display_name":"Ornella Cominetti","orcid":"https://orcid.org/0000-0001-8564-1963"},"institutions":[{"id":"https://openalex.org/I2252230247","display_name":"Institute for Work and Health","ror":"https://ror.org/02rycsd19","country_code":"CH","type":"facility","lineage":["https://openalex.org/I2252230247"]},{"id":"https://openalex.org/I4210112383","display_name":"Nestl\u00e9 (Switzerland)","ror":"https://ror.org/01v5xwf23","country_code":"CH","type":"company","lineage":["https://openalex.org/I4210112383"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Ornella Cominetti","raw_affiliation_strings":["5Nestl\u00e9 Institute of Health Sciences, Lausanne, Switzerland","Nestl\u00e9 Institute of Health Sciences, Lausanne, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"5Nestl\u00e9 Institute of Health Sciences, Lausanne, Switzerland","institution_ids":["https://openalex.org/I2252230247"]},{"raw_affiliation_string":"Nestl\u00e9 Institute of Health Sciences, Lausanne, Switzerland","institution_ids":["https://openalex.org/I4210112383"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112707020","display_name":"Muminatou Jallow","orcid":"https://orcid.org/0009-0007-8122-4557"},"institutions":[{"id":"https://openalex.org/I4210116687","display_name":"MRC Unit the Gambia","ror":"https://ror.org/025wfj672","country_code":"GM","type":"facility","lineage":["https://openalex.org/I124357947","https://openalex.org/I4210087105","https://openalex.org/I4210089966","https://openalex.org/I4210116687","https://openalex.org/I90344618"]}],"countries":["GM"],"is_corresponding":false,"raw_author_name":"Muminatou Jallow","raw_affiliation_strings":["6Medical Research Council Unit, The Gambia, Fajara, P.O. Box 273, Banjul, The Gambia","Medical Research Council Unit, The Gambia, Fajara, P.O. Box 273, Banjul, The Gambia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"6Medical Research Council Unit, The Gambia, Fajara, P.O. Box 273, Banjul, The Gambia","institution_ids":["https://openalex.org/I4210116687"]},{"raw_affiliation_string":"Medical Research Council Unit, The Gambia, Fajara, P.O. Box 273, Banjul, The Gambia","institution_ids":["https://openalex.org/I4210116687"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077751896","display_name":"Dominic Kwiatkowski","orcid":"https://orcid.org/0000-0002-5023-0176"},"institutions":[{"id":"https://openalex.org/I1336263701","display_name":"Centre for Human Genetics","ror":"https://ror.org/01rjnta51","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1336263701","https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Dominic Kwiatkowski","raw_affiliation_strings":["7Wellcome Trust Centre for Human Genetics, Oxford, UK","Wellcome Trust Centre for Human Genetics, Oxford, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"7Wellcome Trust Centre for Human Genetics, Oxford, UK","institution_ids":["https://openalex.org/I1336263701"]},{"raw_affiliation_string":"Wellcome Trust Centre for Human Genetics, Oxford, UK","institution_ids":["https://openalex.org/I1336263701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058010593","display_name":"Mauricio Barahona","orcid":"https://orcid.org/0000-0002-1089-5675"},"institutions":[{"id":"https://openalex.org/I1299528221","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842","country_code":"GB","type":"government","lineage":["https://openalex.org/I1299528221","https://openalex.org/I4210087105"]},{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mauricio Barahona","raw_affiliation_strings":["2EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","4Department of Mathematics, Imperial College London, London, UK","EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","Department of Mathematics, Imperial College London, London, UK"],"raw_orcid":"https://orcid.org/0000-0002-1089-5675","affiliations":[{"raw_affiliation_string":"2EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","institution_ids":["https://openalex.org/I153355300"]},{"raw_affiliation_string":"4Department of Mathematics, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","institution_ids":["https://openalex.org/I1299528221","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Department of Mathematics, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021607726","display_name":"Nick S. Jones","orcid":"https://orcid.org/0000-0002-4083-972X"},"institutions":[{"id":"https://openalex.org/I1299528221","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842","country_code":"GB","type":"government","lineage":["https://openalex.org/I1299528221","https://openalex.org/I4210087105"]},{"id":"https://openalex.org/I153355300","display_name":"Imperial College Healthcare NHS Trust","ror":"https://ror.org/056ffv270","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I153355300"]},{"id":"https://openalex.org/I47508984","display_name":"Imperial College London","ror":"https://ror.org/041kmwe10","country_code":"GB","type":"education","lineage":["https://openalex.org/I47508984"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Nick S. Jones","raw_affiliation_strings":["2EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","4Department of Mathematics, Imperial College London, London, UK","EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","Department of Mathematics, Imperial College London, London, UK"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","institution_ids":["https://openalex.org/I153355300"]},{"raw_affiliation_string":"4Department of Mathematics, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]},{"raw_affiliation_string":"EPSRC Centre for the Mathematics of Precision Healthcare, Imperial College London, London, UK","institution_ids":["https://openalex.org/I1299528221","https://openalex.org/I47508984"]},{"raw_affiliation_string":"Department of Mathematics, Imperial College London, London, UK","institution_ids":["https://openalex.org/I47508984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021718985","display_name":"Climent Casals\u2010Pascual","orcid":"https://orcid.org/0000-0002-0867-8954"},"institutions":[{"id":"https://openalex.org/I1336263701","display_name":"Centre for Human Genetics","ror":"https://ror.org/01rjnta51","country_code":"GB","type":"facility","lineage":["https://openalex.org/I1336263701","https://openalex.org/I40120149"]},{"id":"https://openalex.org/I4210115097","display_name":"Hospital Cl\u00ednic de Barcelona","ror":"https://ror.org/02a2kzf50","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210115097"]},{"id":"https://openalex.org/I4210148332","display_name":"Barcelona Institute for Global Health","ror":"https://ror.org/03hjgt059","country_code":"ES","type":"healthcare","lineage":["https://openalex.org/I4210148332","https://openalex.org/I4387153040"]}],"countries":["ES","GB"],"is_corresponding":false,"raw_author_name":"Climent Casals-Pascual","raw_affiliation_strings":["7Wellcome Trust Centre for Human Genetics, Oxford, UK","Hospital Clinic i Provincial de Barcelona, CDB and ISGlobal, Barcelona, Spain","Wellcome Trust Centre for Human Genetics, Oxford, UK"],"raw_orcid":"https://orcid.org/0000-0002-0867-8954","affiliations":[{"raw_affiliation_string":"7Wellcome Trust Centre for Human Genetics, Oxford, UK","institution_ids":["https://openalex.org/I1336263701"]},{"raw_affiliation_string":"Hospital Clinic i Provincial de Barcelona, CDB and ISGlobal, Barcelona, Spain","institution_ids":["https://openalex.org/I4210115097","https://openalex.org/I4210148332"]},{"raw_affiliation_string":"Wellcome Trust Centre for Human Genetics, Oxford, UK","institution_ids":["https://openalex.org/I1336263701"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5016846029"],"corresponding_institution_ids":["https://openalex.org/I125680101","https://openalex.org/I1299528221","https://openalex.org/I153355300","https://openalex.org/I4210128584","https://openalex.org/I4432739","https://openalex.org/I47508984"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":1.5546,"has_fulltext":true,"cited_by_count":21,"citation_normalized_percentile":{"value":0.83360204,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"2","issue":"1","first_page":"63","last_page":"63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10091","display_name":"Malaria Research and Control","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9943000078201294,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.9621999859809875,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.6676091551780701},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.6593854427337646},{"id":"https://openalex.org/keywords/malaria","display_name":"Malaria","score":0.5152881145477295},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.47509872913360596},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.44298967719078064},{"id":"https://openalex.org/keywords/longitudinal-data","display_name":"Longitudinal data","score":0.4152255654335022},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.31584084033966064},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.23689821362495422},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.22447386384010315},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.15500971674919128},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.13771966099739075},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.08017575740814209}],"concepts":[{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.6676091551780701},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.6593854427337646},{"id":"https://openalex.org/C2778048844","wikidata":"https://www.wikidata.org/wiki/Q12156","display_name":"Malaria","level":2,"score":0.5152881145477295},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.47509872913360596},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.44298967719078064},{"id":"https://openalex.org/C3020672099","wikidata":"https://www.wikidata.org/wiki/Q857354","display_name":"Longitudinal data","level":2,"score":0.4152255654335022},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.31584084033966064},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.23689821362495422},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22447386384010315},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.15500971674919128},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.13771966099739075},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08017575740814209},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":9,"locations":[{"id":"doi:10.1038/s41746-019-0140-y","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0140-y","pdf_url":"https://www.nature.com/articles/s41746-019-0140-y.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:31312723","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31312723","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:diposit.ub.edu:2445/138980","is_oa":true,"landing_page_url":"https://hdl.handle.net/2445/138980","pdf_url":null,"source":{"id":"https://openalex.org/S4306401653","display_name":"Dip\u00f2sit Digital de la Universitat de Barcelona (Universitat de Barcelona)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I71999127","host_organization_name":"Universitat de Barcelona","host_organization_lineage":["https://openalex.org/I71999127"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Articles publicats en revistes (ISGlobal)","raw_type":"info:eu-repo/semantics/publishedVersion"},{"id":"pmh:oai:bora.uib.no:1956/23515","is_oa":true,"landing_page_url":"https://hdl.handle.net/1956/23515","pdf_url":null,"source":{"id":"https://openalex.org/S4306400085","display_name":"Bergen Open Research Archive (BORA) (University of Bergen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4432739","host_organization_name":"University of Bergen","host_organization_lineage":["https://openalex.org/I4432739"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine","raw_type":"info:eu-repo/semantics/other"},{"id":"pmh:oai:doaj.org/article:b2b589f58928401bb258345fb06ba0de","is_oa":true,"landing_page_url":"https://doaj.org/article/b2b589f58928401bb258345fb06ba0de","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 2, Iss 1, Pp 1-9 (2019)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:5593280","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6620311","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:ora.ox.ac.uk:uuid:c1a87cb8-d23c-4b5a-ae8a-19c1d65ef282","is_oa":true,"landing_page_url":"https://ora.ox.ac.uk/objects/uuid:c1a87cb8-d23c-4b5a-ae8a-19c1d65ef282","pdf_url":null,"source":{"id":"https://openalex.org/S4306402636","display_name":"Oxford University Research Archive (ORA) (University of Oxford)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I40120149","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/I40120149"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal article"},{"id":"pmh:oai:recercat.cat:2072/361081","is_oa":true,"landing_page_url":"http://hdl.handle.net/2445/138980","pdf_url":null,"source":{"id":"https://openalex.org/S4306402147","display_name":"RECERCAT (Consorci de Serveis Universitaris de Catalunya)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210090028","host_organization_name":"Consorci de Serveis Universitaris de Catalunya","host_organization_lineage":["https://openalex.org/I4210090028"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:spiral.imperial.ac.uk:10044/1/71535","is_oa":true,"landing_page_url":"http://hdl.handle.net/10044/1/71535","pdf_url":null,"source":{"id":"https://openalex.org/S4306401396","display_name":"Spiral (Imperial College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I47508984","host_organization_name":"Imperial College London","host_organization_lineage":["https://openalex.org/I47508984"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1038/s41746-019-0140-y","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0140-y","pdf_url":"https://www.nature.com/articles/s41746-019-0140-y.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8700000047683716,"display_name":"Good health and well-being"}],"awards":[{"id":"https://openalex.org/G1201428007","display_name":null,"funder_award_id":"MR/M006212/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G2004511894","display_name":null,"funder_award_id":"G0701885","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"},{"id":"https://openalex.org/G2453345397","display_name":null,"funder_award_id":"EP/N014529/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G3074060134","display_name":null,"funder_award_id":"G070188","funder_id":"https://openalex.org/F4320338126","funder_display_name":"Medical Research Foundation"},{"id":"https://openalex.org/G7417950124","display_name":"EPSRC Centre for Mathematics of Precision Healthcare","funder_award_id":"EP/N014529/1","funder_id":"https://openalex.org/F4320334627","funder_display_name":"Engineering and Physical Sciences Research Council"},{"id":"https://openalex.org/G8618014225","display_name":null,"funder_award_id":"077383/Z/05/Z","funder_id":"https://openalex.org/F4320311904","funder_display_name":"Wellcome Trust"}],"funders":[{"id":"https://openalex.org/F4320306080","display_name":"Foundation for the National Institutes of Health","ror":"https://ror.org/00k86s890"},{"id":"https://openalex.org/F4320306137","display_name":"Bill and Melinda Gates Foundation","ror":"https://ror.org/0456r8d26"},{"id":"https://openalex.org/F4320311904","display_name":"Wellcome Trust","ror":"https://ror.org/029chgv08"},{"id":"https://openalex.org/F4320313467","display_name":"Alan Turing Institute","ror":"https://ror.org/035dkdb55"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"},{"id":"https://openalex.org/F4320334627","display_name":"Engineering and Physical Sciences Research Council","ror":"https://ror.org/0439y7842"},{"id":"https://openalex.org/F4320338126","display_name":"Medical Research Foundation","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2961700348.pdf","grobid_xml":"https://content.openalex.org/works/W2961700348.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W1928373920","https://openalex.org/W1965418384","https://openalex.org/W1965627045","https://openalex.org/W1999933038","https://openalex.org/W2019411299","https://openalex.org/W2026014108","https://openalex.org/W2069196178","https://openalex.org/W2078099795","https://openalex.org/W2091134111","https://openalex.org/W2093400784","https://openalex.org/W2096883458","https://openalex.org/W2121044470","https://openalex.org/W2280923288","https://openalex.org/W2322213143","https://openalex.org/W2553595002","https://openalex.org/W2594022964","https://openalex.org/W2963341094","https://openalex.org/W3016210511","https://openalex.org/W3017143921","https://openalex.org/W4211010162","https://openalex.org/W4254196027","https://openalex.org/W4300875451"],"related_works":["https://openalex.org/W2115261803","https://openalex.org/W4367362025","https://openalex.org/W2108574175","https://openalex.org/W2347627655","https://openalex.org/W1477123016","https://openalex.org/W2386208584","https://openalex.org/W2226154164","https://openalex.org/W2368864186","https://openalex.org/W3122661184","https://openalex.org/W2371118503"],"abstract_inverted_index":{"More":[0],"than":[1],"400,000":[2],"deaths":[3],"from":[4,47],"severe":[5],"malaria":[6,138],"(SM)":[7],"are":[8],"reported":[9],"every":[10],"year,":[11],"mainly":[12],"in":[13,27,61,69],"African":[14],"children.":[15],"The":[16],"diversity":[17],"of":[18,38,63,86,94,105,135],"clinical":[19,36,64,148],"presentations":[20],"associated":[21,66],"with":[22,67,76,129],"SM":[23,39,68,95],"indicates":[24],"important":[25],"differences":[26],"disease":[28],"pathogenesis":[29],"that":[30,124],"require":[31],"specific":[32],"treatment,":[33],"and":[34,50,57,90,130],"this":[35,125],"heterogeneity":[37,60],"remains":[40],"poorly":[41],"understood.":[42],"Here,":[43],"we":[44,122],"apply":[45],"tools":[46],"machine":[48],"learning":[49],"model-based":[51],"inference":[52,104],"to":[53,74,114],"harness":[54],"large-scale":[55],"data":[56],"dissect":[58],"the":[59,84,91,132],"patterns":[62],"features":[65,82],"2904":[70],"Gambian":[71],"children":[72],"admitted":[73],"hospital":[75],"malaria.":[77],"This":[78],"quantitative":[79,111],"analysis":[80],"reveals":[81],"predicting":[83,147],"severity":[85],"individual":[87,115],"patient":[88],"outcomes,":[89],"dynamic":[92],"pathways":[93,107],"progression,":[96,139],"notably":[97],"inferred":[98],"without":[99],"requiring":[100],"longitudinal":[101],"observations.":[102],"Bayesian":[103],"these":[106],"allows":[108],"us":[109],"assign":[110],"mortality":[112],"risks":[113],"patients.":[116],"By":[117],"independently":[118],"surveying":[119],"expert":[120],"practitioners,":[121],"show":[123],"data-driven":[126],"approach":[127],"agrees":[128],"expands":[131],"current":[133],"state":[134],"knowledge":[136],"on":[137],"while":[140],"simultaneously":[141],"providing":[142],"a":[143],"data-supported":[144],"framework":[145],"for":[146],"risk.":[149]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":8},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}