{"id":"https://openalex.org/W2912652107","doi":"https://doi.org/10.1038/s41746-019-0079-z","title":"The reproducibility crisis in the age of digital medicine","display_name":"The reproducibility crisis in the age of digital medicine","publication_year":2019,"publication_date":"2019-01-29","ids":{"openalex":"https://openalex.org/W2912652107","doi":"https://doi.org/10.1038/s41746-019-0079-z","mag":"2912652107","pmid":"https://pubmed.ncbi.nlm.nih.gov/31304352"},"language":"en","primary_location":{"id":"doi:10.1038/s41746-019-0079-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0079-z","pdf_url":"https://www.nature.com/articles/s41746-019-0079-z.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41746-019-0079-z.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004131103","display_name":"Aaron Stupple","orcid":null},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I1338449461","display_name":"Baystate Medical Center","ror":"https://ror.org/01q2nz307","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1338449461"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Aaron Stupple","raw_affiliation_strings":["1Baystate Medical Center, Springfield, MA USA","2Beth Israel Deaconess Medical Center, Boston, MA USA","Baystate Medical Center, Springfield, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Baystate Medical Center, Springfield, MA USA","institution_ids":["https://openalex.org/I1338449461"]},{"raw_affiliation_string":"2Beth Israel Deaconess Medical Center, Boston, MA USA","institution_ids":["https://openalex.org/I1316535847"]},{"raw_affiliation_string":"Baystate Medical Center, Springfield, MA, USA","institution_ids":["https://openalex.org/I1338449461"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036720440","display_name":"David Singerman","orcid":null},"institutions":[{"id":"https://openalex.org/I51556381","display_name":"University of Virginia","ror":"https://ror.org/0153tk833","country_code":"US","type":"education","lineage":["https://openalex.org/I51556381"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David Singerman","raw_affiliation_strings":["3University of Virginia, Charlottesville, VA USA","University of Virginia, Charlottesville, VA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3University of Virginia, Charlottesville, VA USA","institution_ids":["https://openalex.org/I51556381"]},{"raw_affiliation_string":"University of Virginia, Charlottesville, VA, USA","institution_ids":["https://openalex.org/I51556381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5031401755","display_name":"Leo Anthony Celi","orcid":"https://orcid.org/0000-0001-6712-6626"},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leo Anthony Celi","raw_affiliation_strings":["2Beth Israel Deaconess Medical Center, Boston, MA USA","4Massachusetts Institute of Technology, Cambridge, MA USA","Beth Israel Deaconess Medical Center, Boston, MA, USA"],"raw_orcid":"https://orcid.org/0000-0001-6712-6626","affiliations":[{"raw_affiliation_string":"2Beth Israel Deaconess Medical Center, Boston, MA USA","institution_ids":["https://openalex.org/I1316535847"]},{"raw_affiliation_string":"4Massachusetts Institute of Technology, Cambridge, MA USA","institution_ids":["https://openalex.org/I63966007"]},{"raw_affiliation_string":"Beth Israel Deaconess Medical Center, Boston, MA, USA","institution_ids":["https://openalex.org/I1316535847"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5004131103"],"corresponding_institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I1338449461"],"apc_list":{"value":3060,"currency":"USD","value_usd":3060},"apc_paid":{"value":3060,"currency":"USD","value_usd":3060},"fwci":19.0993,"has_fulltext":true,"cited_by_count":143,"citation_normalized_percentile":{"value":0.99609621,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"2","issue":"1","first_page":"2","last_page":"2"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13953","display_name":"Digital Imaging in Medicine","score":0.9776999950408936,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13953","display_name":"Digital Imaging in Medicine","score":0.9776999950408936,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.977400004863739,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13607","display_name":"Academic Publishing and Open Access","score":0.965399980545044,"subfield":{"id":"https://openalex.org/subfields/1802","display_name":"Information Systems and Management"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/reproducibility","display_name":"Reproducibility","score":0.8556764125823975},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.32959145307540894},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.14795520901679993},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.13887277245521545}],"concepts":[{"id":"https://openalex.org/C9893847","wikidata":"https://www.wikidata.org/wiki/Q1425625","display_name":"Reproducibility","level":2,"score":0.8556764125823975},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32959145307540894},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.14795520901679993},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.13887277245521545}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1038/s41746-019-0079-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0079-z","pdf_url":"https://www.nature.com/articles/s41746-019-0079-z.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},{"id":"pmid:31304352","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31304352","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"NPJ digital medicine","raw_type":null},{"id":"pmh:oai:doaj.org/article:cfea61d287b04b948a63ee29d44538dd","is_oa":true,"landing_page_url":"https://doaj.org/article/cfea61d287b04b948a63ee29d44538dd","pdf_url":null,"source":{"id":"https://openalex.org/S112646816","display_name":"SHILAP Revista de lepidopterolog\u00eda","issn_l":"0300-5267","issn":["0300-5267","2340-4078"],"is_oa":true,"is_in_doaj":true,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"npj Digital Medicine, Vol 2, Iss 1, Pp 1-3 (2019)","raw_type":"article"},{"id":"pmh:oai:dspace.mit.edu:1721.1/124903","is_oa":true,"landing_page_url":"https://hdl.handle.net/1721.1/124903","pdf_url":null,"source":{"id":"https://openalex.org/S4306400425","display_name":"DSpace@MIT (Massachusetts Institute of Technology)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I63966007","host_organization_name":"Massachusetts Institute of Technology","host_organization_lineage":["https://openalex.org/I63966007"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature","raw_type":"http://purl.org/eprint/type/JournalArticle"},{"id":"pmh:oai:europepmc.org:5586866","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6550262","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1038/s41746-019-0079-z","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41746-019-0079-z","pdf_url":"https://www.nature.com/articles/s41746-019-0079-z.pdf","source":{"id":"https://openalex.org/S4210195431","display_name":"npj Digital Medicine","issn_l":"2398-6352","issn":["2398-6352"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"npj Digital Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.6499999761581421,"id":"https://metadata.un.org/sdg/5","display_name":"Gender equality"}],"awards":[{"id":"https://openalex.org/G7597440964","display_name":null,"funder_award_id":"EB017205","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"}],"funders":[{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2912652107.pdf","grobid_xml":"https://content.openalex.org/works/W2912652107.grobid-xml"},"referenced_works_count":16,"referenced_works":["https://openalex.org/W1869963300","https://openalex.org/W1897139626","https://openalex.org/W2059813502","https://openalex.org/W2160453617","https://openalex.org/W2161498332","https://openalex.org/W2171059877","https://openalex.org/W2172129432","https://openalex.org/W2263593861","https://openalex.org/W2335400770","https://openalex.org/W2339294314","https://openalex.org/W2406493898","https://openalex.org/W2414283705","https://openalex.org/W2584547955","https://openalex.org/W2891367027","https://openalex.org/W2904730732","https://openalex.org/W2909137243"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W3031052312","https://openalex.org/W4389568370","https://openalex.org/W3032375762","https://openalex.org/W1995515455","https://openalex.org/W2080531066","https://openalex.org/W2586801360","https://openalex.org/W3108674512","https://openalex.org/W1506200166","https://openalex.org/W1489783725"],"abstract_inverted_index":{"If":[0],"anyone":[1],"doubts":[2],"the":[3,22,34,43,50,72],"explosive":[4],"growth":[5],"of":[6,38,45,52],"interest":[7],"in":[8,17,65],"digital":[9],"medicine,":[10],"consider":[11],"a":[12,59,66],"recent":[13],"conference":[14],"and":[15,28,36,61,63],"workshop":[16],"Beijing,":[18],"jointly":[19],"organized":[20],"by":[21],"People\u2019s":[23],"Liberation":[24],"Army":[25],"General":[26],"Hospital":[27],"MIT":[29],"Critical":[30],"Data":[31],"to":[32,42,76],"showcase":[33],"opportunities":[35],"challenges":[37],"applying":[39],"machine":[40],"learning":[41],"kind":[44],"data":[46,68],"routinely":[47],"collected":[48],"during":[49],"provision":[51],"care.1":[53],"In":[54],"person,":[55],"500":[56],"attendees":[57],"heard":[58],"keynote":[60],"panels":[62],"participated":[64],"health":[67],"hackathon.":[69],"Online,":[70],"however,":[71],"event":[73],"was":[74],"streamed":[75],"more":[77],"than":[78],"one":[79],"million":[80],"unique":[81],"viewers.":[82],"\u00a92020":[83],"[First":[84],"paragraph]":[85]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":18},{"year":2023,"cited_by_count":27},{"year":2022,"cited_by_count":28},{"year":2021,"cited_by_count":26},{"year":2020,"cited_by_count":20},{"year":2019,"cited_by_count":12}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}