{"id":"https://openalex.org/W1557797865","doi":"https://doi.org/10.1023/a:1015930031890","title":"Design and synthesis of type-III mimetics of \u03c9-conotoxin GVIA","display_name":"Design and synthesis of type-III mimetics of \u03c9-conotoxin GVIA","publication_year":2001,"publication_date":"2001-12-01","ids":{"openalex":"https://openalex.org/W1557797865","doi":"https://doi.org/10.1023/a:1015930031890","mag":"1557797865","pmid":"https://pubmed.ncbi.nlm.nih.gov/12160094"},"language":"en","primary_location":{"id":"doi:10.1023/a:1015930031890","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1015930031890","pdf_url":null,"source":{"id":"https://openalex.org/S64621741","display_name":"Journal of Computer-Aided Molecular Design","issn_l":"0920-654X","issn":["0920-654X","1573-4951"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Computer-Aided Molecular Design","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040184200","display_name":"Jonathan B. Baell","orcid":"https://orcid.org/0000-0003-2114-8242"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jonathan B. Baell","raw_affiliation_strings":["Biomolecular Research Institute, Parkville, Victoria, Australia. jbaell@wehi.edu.au","Biomolecular Research Institute, Parkville, Victoria, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomolecular Research Institute, Parkville, Victoria, Australia. jbaell@wehi.edu.au","institution_ids":[]},{"raw_affiliation_string":"Biomolecular Research Institute, Parkville, Victoria, Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058651202","display_name":"Stewart A. Forsyth","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stewart A. Forsyth","raw_affiliation_strings":["Biomolecular Research Institute, 343 Royal Parade, Parkville, Victoria, 3052, Australia","Biomolecular Research Institute, Parkville, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomolecular Research Institute, 343 Royal Parade, Parkville, Victoria, 3052, Australia","institution_ids":[]},{"raw_affiliation_string":"Biomolecular Research Institute, Parkville, Australia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069032618","display_name":"Robert W. Gable","orcid":"https://orcid.org/0000-0002-4626-0217"},"institutions":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Robert W. Gable","raw_affiliation_strings":["School of Chemistry, University of Melbourne, Parkville, Victoria, 3052, Australia","School of Chemistry, University of Melbourne,Parkville,Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, University of Melbourne, Parkville, Victoria, 3052, Australia","institution_ids":["https://openalex.org/I165779595"]},{"raw_affiliation_string":"School of Chemistry, University of Melbourne,Parkville,Australia","institution_ids":["https://openalex.org/I165779595"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039797008","display_name":"Raymond S. Norton","orcid":"https://orcid.org/0000-0001-8893-0584"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Raymond S. Norton","raw_affiliation_strings":["Biomolecular Research Institute, 343 Royal Parade, Parkville, Victoria, 3052, Australia","Biomolecular Research Institute, Parkville, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomolecular Research Institute, 343 Royal Parade, Parkville, Victoria, 3052, Australia","institution_ids":[]},{"raw_affiliation_string":"Biomolecular Research Institute, Parkville, Australia","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086369378","display_name":"Roger J. Mulder","orcid":"https://orcid.org/0000-0002-8740-802X"},"institutions":[{"id":"https://openalex.org/I4210154771","display_name":"CSIRO Manufacturing","ror":"https://ror.org/04sx9wp33","country_code":"AU","type":"facility","lineage":["https://openalex.org/I1292875679","https://openalex.org/I2801453606","https://openalex.org/I4210154771","https://openalex.org/I4387156119"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Roger J. Mulder","raw_affiliation_strings":["CSIRO Molecular Science, Bayview Avenue, Clayton, Victoria, 3168, Australia","CSIRO Molecular Science, Clayton, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CSIRO Molecular Science, Bayview Avenue, Clayton, Victoria, 3168, Australia","institution_ids":["https://openalex.org/I4210154771"]},{"raw_affiliation_string":"CSIRO Molecular Science, Clayton, Australia","institution_ids":["https://openalex.org/I4210154771"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5040184200"],"corresponding_institution_ids":[],"apc_list":{"value":3690,"currency":"USD","value_usd":3690},"apc_paid":null,"fwci":0.7825,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.68592896,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"15","issue":"12","first_page":"1119","last_page":"1136"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.9980999827384949,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9925000071525574,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pharmacophore","display_name":"Pharmacophore","score":0.911140501499176},{"id":"https://openalex.org/keywords/rational-design","display_name":"Rational design","score":0.6858958005905151},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.4660106301307678},{"id":"https://openalex.org/keywords/voltage-dependent-calcium-channel","display_name":"Voltage-dependent calcium channel","score":0.4190948009490967},{"id":"https://openalex.org/keywords/stereochemistry","display_name":"Stereochemistry","score":0.36790281534194946},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.32752525806427},{"id":"https://openalex.org/keywords/calcium","display_name":"Calcium","score":0.29471030831336975},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.21513503789901733},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.21175441145896912}],"concepts":[{"id":"https://openalex.org/C56173144","wikidata":"https://www.wikidata.org/wiki/Q1539893","display_name":"Pharmacophore","level":2,"score":0.911140501499176},{"id":"https://openalex.org/C53105671","wikidata":"https://www.wikidata.org/wiki/Q14777816","display_name":"Rational design","level":2,"score":0.6858958005905151},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4660106301307678},{"id":"https://openalex.org/C18699975","wikidata":"https://www.wikidata.org/wiki/Q14905735","display_name":"Voltage-dependent calcium channel","level":3,"score":0.4190948009490967},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.36790281534194946},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32752525806427},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.29471030831336975},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.21513503789901733},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.21175441145896912},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000700","descriptor_name":"Analgesics","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D000700","descriptor_name":"Analgesics","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D000700","descriptor_name":"Analgesics","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D000700","descriptor_name":"Analgesics","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000700","descriptor_name":"Analgesics","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000700","descriptor_name":"Analgesics","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000138","qualifier_name":"chemical synthesis","is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002121","descriptor_name":"Calcium Channel Blockers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018360","descriptor_name":"Crystallography, X-Ray","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018716","descriptor_name":"Molecular Mimicry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018716","descriptor_name":"Molecular Mimicry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018716","descriptor_name":"Molecular Mimicry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020864","descriptor_name":"Calcium Channels, N-Type","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020864","descriptor_name":"Calcium Channels, N-Type","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020864","descriptor_name":"Calcium Channels, N-Type","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D020864","descriptor_name":"Calcium Channels, N-Type","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020864","descriptor_name":"Calcium Channels, N-Type","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020864","descriptor_name":"Calcium Channels, N-Type","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020866","descriptor_name":"omega-Conotoxin GVIA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020866","descriptor_name":"omega-Conotoxin GVIA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020866","descriptor_name":"omega-Conotoxin GVIA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1023/a:1015930031890","is_oa":false,"landing_page_url":"https://doi.org/10.1023/a:1015930031890","pdf_url":null,"source":{"id":"https://openalex.org/S64621741","display_name":"Journal of Computer-Aided Molecular Design","issn_l":"0920-654X","issn":["0920-654X","1573-4951"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Computer-Aided Molecular Design","raw_type":"journal-article"},{"id":"pmid:12160094","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12160094","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of computer-aided molecular design","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W1524020507","https://openalex.org/W1559023027","https://openalex.org/W1682432998","https://openalex.org/W1757122036","https://openalex.org/W1964007399","https://openalex.org/W1976311113","https://openalex.org/W1980353405","https://openalex.org/W1987934686","https://openalex.org/W1989897116","https://openalex.org/W1992927105","https://openalex.org/W1995096415","https://openalex.org/W1995628404","https://openalex.org/W1998295767","https://openalex.org/W1999903020","https://openalex.org/W2006546086","https://openalex.org/W2010143056","https://openalex.org/W2014985938","https://openalex.org/W2035349592","https://openalex.org/W2036015954","https://openalex.org/W2051710717","https://openalex.org/W2058527555","https://openalex.org/W2061761037","https://openalex.org/W2065489607","https://openalex.org/W2070622053","https://openalex.org/W2071579644","https://openalex.org/W2076089746","https://openalex.org/W2081544730","https://openalex.org/W2081992461","https://openalex.org/W2093531044","https://openalex.org/W2107399000","https://openalex.org/W2126208045","https://openalex.org/W2128327963","https://openalex.org/W2144843461","https://openalex.org/W2161612482","https://openalex.org/W2470665108","https://openalex.org/W2953075186","https://openalex.org/W3012644729","https://openalex.org/W4234267701","https://openalex.org/W4253658821"],"related_works":["https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W3186149425","https://openalex.org/W1973585853","https://openalex.org/W2035635611","https://openalex.org/W2800612750","https://openalex.org/W2318181632","https://openalex.org/W2288574192","https://openalex.org/W1557797865","https://openalex.org/W2129396168"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":7}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}