{"id":"https://openalex.org/W2036271007","doi":"https://doi.org/10.1021/ci200017f","title":"Computational Evidence for the Role of <i>Arabidopsis thaliana</i> UVR8 as UV\u2013B Photoreceptor and Identification of Its Chromophore Amino Acids","display_name":"Computational Evidence for the Role of <i>Arabidopsis thaliana</i> UVR8 as UV\u2013B Photoreceptor and Identification of Its Chromophore Amino Acids","publication_year":2011,"publication_date":"2011-05-11","ids":{"openalex":"https://openalex.org/W2036271007","doi":"https://doi.org/10.1021/ci200017f","mag":"2036271007"},"language":"en","primary_location":{"id":"doi:10.1021/ci200017f","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ci200017f","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072606310","display_name":"Min Wu","orcid":"https://orcid.org/0000-0003-0550-5801"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":true,"raw_author_name":"Min Wu","raw_affiliation_strings":["School of Chemistry, National University of Ireland - Galway, Galway, Ireland"],"affiliations":[{"raw_affiliation_string":"School of Chemistry, National University of Ireland - Galway, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079220177","display_name":"E. Grahn","orcid":null},"institutions":[{"id":"https://openalex.org/I26437253","display_name":"\u00d6rebro University","ror":"https://ror.org/05kytsw45","country_code":"SE","type":"education","lineage":["https://openalex.org/I26437253"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Elin Grahn","raw_affiliation_strings":["\u00d6rebro Life Science Center, School of Science and Technology, \u00d6rebro University, 70182 \u00d6rebro, Sweden"],"affiliations":[{"raw_affiliation_string":"\u00d6rebro Life Science Center, School of Science and Technology, \u00d6rebro University, 70182 \u00d6rebro, Sweden","institution_ids":["https://openalex.org/I26437253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001315059","display_name":"Leif A. Eriksson","orcid":"https://orcid.org/0000-0001-5654-3109"},"institutions":[{"id":"https://openalex.org/I188760350","display_name":"Ollscoil na Gaillimhe \u2013 University of Galway","ror":"https://ror.org/03bea9k73","country_code":"IE","type":"education","lineage":["https://openalex.org/I188760350"]}],"countries":["IE"],"is_corresponding":false,"raw_author_name":"Leif A. Eriksson","raw_affiliation_strings":["School of Chemistry, National University of Ireland - Galway, Galway, Ireland"],"affiliations":[{"raw_affiliation_string":"School of Chemistry, National University of Ireland - Galway, Galway, Ireland","institution_ids":["https://openalex.org/I188760350"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065532211","display_name":"\u00c5ke Strid","orcid":"https://orcid.org/0000-0003-3315-8835"},"institutions":[{"id":"https://openalex.org/I26437253","display_name":"\u00d6rebro University","ror":"https://ror.org/05kytsw45","country_code":"SE","type":"education","lineage":["https://openalex.org/I26437253"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"\u00c5ke Strid","raw_affiliation_strings":["\u00d6rebro Life Science Center, School of Science and Technology, \u00d6rebro University, 70182 \u00d6rebro, Sweden"],"affiliations":[{"raw_affiliation_string":"\u00d6rebro Life Science Center, School of Science and Technology, \u00d6rebro University, 70182 \u00d6rebro, Sweden","institution_ids":["https://openalex.org/I26437253"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5072606310"],"corresponding_institution_ids":["https://openalex.org/I188760350"],"apc_list":null,"apc_paid":null,"fwci":6.4255,"has_fulltext":false,"cited_by_count":42,"citation_normalized_percentile":{"value":0.96086999,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"51","issue":"6","first_page":"1287","last_page":"1295"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11268","display_name":"Light effects on plants","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11268","display_name":"Light effects on plants","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":0.9771999716758728,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12180","display_name":"Polar Research and Ecology","score":0.960099995136261,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.5706311464309692},{"id":"https://openalex.org/keywords/amino-acid","display_name":"Amino acid","score":0.5422689318656921},{"id":"https://openalex.org/keywords/arabidopsis-thaliana","display_name":"Arabidopsis thaliana","score":0.5283166766166687},{"id":"https://openalex.org/keywords/stereochemistry","display_name":"Stereochemistry","score":0.47799745202064514},{"id":"https://openalex.org/keywords/homology-modeling","display_name":"Homology modeling","score":0.4635196626186371},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.463421493768692},{"id":"https://openalex.org/keywords/chromophore","display_name":"Chromophore","score":0.4588828980922699},{"id":"https://openalex.org/keywords/arabidopsis","display_name":"Arabidopsis","score":0.45207855105400085},{"id":"https://openalex.org/keywords/amino-acid-residue","display_name":"Amino acid residue","score":0.43020254373550415},{"id":"https://openalex.org/keywords/threonine","display_name":"Threonine","score":0.4240695536136627},{"id":"https://openalex.org/keywords/residue","display_name":"Residue (chemistry)","score":0.4132674038410187},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.34479820728302},{"id":"https://openalex.org/keywords/peptide-sequence","display_name":"Peptide sequence","score":0.32557982206344604},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.32441556453704834},{"id":"https://openalex.org/keywords/serine","display_name":"Serine","score":0.2895313501358032},{"id":"https://openalex.org/keywords/mutant","display_name":"Mutant","score":0.2423611283302307},{"id":"https://openalex.org/keywords/photochemistry","display_name":"Photochemistry","score":0.12999919056892395},{"id":"https://openalex.org/keywords/phosphorylation","display_name":"Phosphorylation","score":0.11072865128517151}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5706311464309692},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.5422689318656921},{"id":"https://openalex.org/C2775988993","wikidata":"https://www.wikidata.org/wiki/Q158695","display_name":"Arabidopsis thaliana","level":4,"score":0.5283166766166687},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.47799745202064514},{"id":"https://openalex.org/C169627665","wikidata":"https://www.wikidata.org/wiki/Q5767913","display_name":"Homology modeling","level":3,"score":0.4635196626186371},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.463421493768692},{"id":"https://openalex.org/C192468462","wikidata":"https://www.wikidata.org/wiki/Q533543","display_name":"Chromophore","level":2,"score":0.4588828980922699},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.45207855105400085},{"id":"https://openalex.org/C2994376932","wikidata":"https://www.wikidata.org/wiki/Q735188","display_name":"Amino acid residue","level":4,"score":0.43020254373550415},{"id":"https://openalex.org/C2775880066","wikidata":"https://www.wikidata.org/wiki/Q186521","display_name":"Threonine","level":4,"score":0.4240695536136627},{"id":"https://openalex.org/C2781338088","wikidata":"https://www.wikidata.org/wiki/Q903495","display_name":"Residue (chemistry)","level":2,"score":0.4132674038410187},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.34479820728302},{"id":"https://openalex.org/C167625842","wikidata":"https://www.wikidata.org/wiki/Q899763","display_name":"Peptide sequence","level":3,"score":0.32557982206344604},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32441556453704834},{"id":"https://openalex.org/C2776414213","wikidata":"https://www.wikidata.org/wiki/Q183290","display_name":"Serine","level":3,"score":0.2895313501358032},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.2423611283302307},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.12999919056892395},{"id":"https://openalex.org/C11960822","wikidata":"https://www.wikidata.org/wiki/Q242736","display_name":"Phosphorylation","level":2,"score":0.11072865128517151},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/ci200017f","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ci200017f","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320311521","display_name":"National University of Ireland","ror":"https://ror.org/00shsf120"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1565653332","https://openalex.org/W1604830889","https://openalex.org/W1946679520","https://openalex.org/W1989730190","https://openalex.org/W1991667226","https://openalex.org/W2000798385","https://openalex.org/W2015704046","https://openalex.org/W2019364309","https://openalex.org/W2024449122","https://openalex.org/W2036217839","https://openalex.org/W2044355402","https://openalex.org/W2053745008","https://openalex.org/W2053922644","https://openalex.org/W2065874759","https://openalex.org/W2082949074","https://openalex.org/W2097903157","https://openalex.org/W2099099776","https://openalex.org/W2100744249","https://openalex.org/W2100951456","https://openalex.org/W2112850441","https://openalex.org/W2122027991","https://openalex.org/W2126610272","https://openalex.org/W2131057399","https://openalex.org/W2133538560","https://openalex.org/W2134210612","https://openalex.org/W2135959854","https://openalex.org/W2137527519","https://openalex.org/W2141542056","https://openalex.org/W2143981217","https://openalex.org/W2148019935","https://openalex.org/W2148284063","https://openalex.org/W2155481116","https://openalex.org/W2165402269","https://openalex.org/W2167222308","https://openalex.org/W2978747149"],"related_works":["https://openalex.org/W2118668532","https://openalex.org/W2088314087","https://openalex.org/W2170681347","https://openalex.org/W2008627400","https://openalex.org/W2296931932","https://openalex.org/W2026289228","https://openalex.org/W1970032998","https://openalex.org/W2064298333","https://openalex.org/W1996355588","https://openalex.org/W1995371071"],"abstract_inverted_index":{"A":[0],"homology":[1,43],"model":[2,44,85],"of":[3,26,38,48,56,72,77,80,134],"the":[4,23,42,53,57,101,106,113,123,130,155],"Arabidopsis":[5],"thaliana":[6,140],"UV":[7],"resistance":[8],"locus":[9],"8":[10],"(UVR8)":[11],"protein":[12,59],"is":[13],"presented":[14],"herein,":[15],"showing":[16],"a":[17,34,70,82],"seven-bladed":[18],"\u03b2-propeller":[19],"conformation":[20],"similar":[21],"to":[22,157],"globular":[24],"structure":[25],"RCC1.":[27],"The":[28],"UVR8":[29,58,149],"amino":[30],"acid":[31],"sequence":[32],"contains":[33],"very":[35],"high":[36],"amount":[37],"conserved":[39],"tryptophans,":[40],"and":[41,69,91,116],"shows":[45],"that":[46,96,148],"seven":[47],"these":[49,145],"tryptophans":[50,115],"cluster":[51,84,108],"at":[52],"'top":[54],"surface\u2019":[55],"where":[60],"they":[61],"are":[62],"intermixed":[63],"with":[64,122],"positive":[65],"residues":[66,90],"(mainly":[67],"arginines)":[68],"couple":[71],"tyrosines.":[73],"Quantum":[74],"chemical":[75],"calculations":[76],"excitation":[78],"spectra":[79],"both":[81],"large":[83],"involving":[86],"all":[87],"twelve":[88],"above-mentioned":[89],"smaller":[92],"fragments":[93],"thereof":[94],"reveal":[95],"absorption":[97],"maxima":[98],"appearing":[99],"in":[100,137,151,153,162],"280\u2013300":[102],"nm":[103],"range":[104],"for":[105,129],"full":[107],"result":[109],"from":[110],"interactions":[111],"between":[112],"central":[114],"surrounding":[117],"arginines.":[118],"This":[119],"observation":[120],"coincides":[121],"published":[124],"experimentally":[125],"measured":[126],"action":[127],"spectrum":[128],"UVR8-dependent":[131],"UV\u2013B":[132],"stimulation":[133],"HY5":[135],"transcription":[136],"mature":[138],"A.":[139],"leaf":[141],"tissue.":[142],"In":[143],"total":[144],"findings":[146],"suggest":[147],"has":[150],"fact":[152],"itself":[154],"ability":[156],"be":[158],"an":[159],"ultraviolet-B":[160],"photoreceptor":[161],"plants.":[163]},"counts_by_year":[{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":6}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2016-06-24T00:00:00"}