{"id":"https://openalex.org/W1970808627","doi":"https://doi.org/10.1021/ci00060a009","title":"Carbon-13 NMR assignments of the bases in oligodeoxynucleotides: an automated procedure using Bayesian statistics","display_name":"Carbon-13 NMR assignments of the bases in oligodeoxynucleotides: an automated procedure using Bayesian statistics","publication_year":1988,"publication_date":"1988-11-01","ids":{"openalex":"https://openalex.org/W1970808627","doi":"https://doi.org/10.1021/ci00060a009","mag":"1970808627","pmid":"https://pubmed.ncbi.nlm.nih.gov/3235474"},"language":"en","primary_location":{"id":"doi:10.1021/ci00060a009","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ci00060a009","pdf_url":null,"source":{"id":"https://openalex.org/S171559003","display_name":"Journal of Chemical Information and Computer Sciences","issn_l":"0095-2338","issn":["0095-2338","1520-5142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Computer Sciences","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065516203","display_name":"Timothy J. Hyman","orcid":null},"institutions":[{"id":"https://openalex.org/I70983195","display_name":"Syracuse University","ror":"https://ror.org/025r5qe02","country_code":"US","type":"education","lineage":["https://openalex.org/I70983195"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy J. Hyman","raw_affiliation_strings":["NIH Research Resource for NMR and Data Processing, Syracuse University, New York 13244-1200","syracuse University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NIH Research Resource for NMR and Data Processing, Syracuse University, New York 13244-1200","institution_ids":["https://openalex.org/I70983195"]},{"raw_affiliation_string":"syracuse University","institution_ids":["https://openalex.org/I70983195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023894034","display_name":"Eilis Boudreau","orcid":null},"institutions":[{"id":"https://openalex.org/I70983195","display_name":"Syracuse University","ror":"https://ror.org/025r5qe02","country_code":"US","type":"education","lineage":["https://openalex.org/I70983195"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eilis A. Boudreau","raw_affiliation_strings":["syracuse University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"syracuse University","institution_ids":["https://openalex.org/I70983195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109930616","display_name":"Gilles G. Martin","orcid":null},"institutions":[{"id":"https://openalex.org/I70983195","display_name":"Syracuse University","ror":"https://ror.org/025r5qe02","country_code":"US","type":"education","lineage":["https://openalex.org/I70983195"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gilles G. Martin","raw_affiliation_strings":["Syracuse University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Syracuse University","institution_ids":["https://openalex.org/I70983195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009295868","display_name":"Beat M. Jucker","orcid":null},"institutions":[{"id":"https://openalex.org/I70983195","display_name":"Syracuse University","ror":"https://ror.org/025r5qe02","country_code":"US","type":"education","lineage":["https://openalex.org/I70983195"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Beat M. Jucker","raw_affiliation_strings":["syracuse University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"syracuse University","institution_ids":["https://openalex.org/I70983195"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108434804","display_name":"Philip N. Borer","orcid":null},"institutions":[{"id":"https://openalex.org/I70983195","display_name":"Syracuse University","ror":"https://ror.org/025r5qe02","country_code":"US","type":"education","lineage":["https://openalex.org/I70983195"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Philip N. Borer","raw_affiliation_strings":["syracuse University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"syracuse University","institution_ids":["https://openalex.org/I70983195"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109855435","display_name":"George C. Levy","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"George C. Levy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.03966189,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"28","issue":"4","first_page":"226","last_page":"230"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9803000092506409,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9803000092506409,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.963699996471405,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9573000073432922,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bayes-theorem","display_name":"Bayes' theorem","score":0.6701071262359619},{"id":"https://openalex.org/keywords/bayesian-probability","display_name":"Bayesian probability","score":0.5676400661468506},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.5324685573577881},{"id":"https://openalex.org/keywords/carbon-fibers","display_name":"Carbon fibers","score":0.5199626684188843},{"id":"https://openalex.org/keywords/class","display_name":"Class (philosophy)","score":0.5152852535247803},{"id":"https://openalex.org/keywords/data-set","display_name":"Data set","score":0.4983677864074707},{"id":"https://openalex.org/keywords/base","display_name":"Base (topology)","score":0.49362409114837646},{"id":"https://openalex.org/keywords/bayes-factor","display_name":"Bayes factor","score":0.49244555830955505},{"id":"https://openalex.org/keywords/oligomer","display_name":"Oligomer","score":0.4671449363231659},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.44570836424827576},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.4364367425441742},{"id":"https://openalex.org/keywords/chemical-shift","display_name":"Chemical shift","score":0.42769432067871094},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.4208643436431885},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.383367121219635},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.35966062545776367},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.3452022671699524},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3346119523048401},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.2883260250091553},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.11180168390274048},{"id":"https://openalex.org/keywords/physical-chemistry","display_name":"Physical chemistry","score":0.10398462414741516}],"concepts":[{"id":"https://openalex.org/C207201462","wikidata":"https://www.wikidata.org/wiki/Q182505","display_name":"Bayes' theorem","level":3,"score":0.6701071262359619},{"id":"https://openalex.org/C107673813","wikidata":"https://www.wikidata.org/wiki/Q812534","display_name":"Bayesian probability","level":2,"score":0.5676400661468506},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.5324685573577881},{"id":"https://openalex.org/C140205800","wikidata":"https://www.wikidata.org/wiki/Q5860","display_name":"Carbon fibers","level":3,"score":0.5199626684188843},{"id":"https://openalex.org/C2777212361","wikidata":"https://www.wikidata.org/wiki/Q5127848","display_name":"Class (philosophy)","level":2,"score":0.5152852535247803},{"id":"https://openalex.org/C58489278","wikidata":"https://www.wikidata.org/wiki/Q1172284","display_name":"Data set","level":2,"score":0.4983677864074707},{"id":"https://openalex.org/C42058472","wikidata":"https://www.wikidata.org/wiki/Q810214","display_name":"Base (topology)","level":2,"score":0.49362409114837646},{"id":"https://openalex.org/C142291917","wikidata":"https://www.wikidata.org/wiki/Q4165283","display_name":"Bayes factor","level":4,"score":0.49244555830955505},{"id":"https://openalex.org/C2780642029","wikidata":"https://www.wikidata.org/wiki/Q726004","display_name":"Oligomer","level":2,"score":0.4671449363231659},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.44570836424827576},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.4364367425441742},{"id":"https://openalex.org/C111429119","wikidata":"https://www.wikidata.org/wiki/Q899127","display_name":"Chemical shift","level":2,"score":0.42769432067871094},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.4208643436431885},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.383367121219635},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35966062545776367},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3452022671699524},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3346119523048401},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2883260250091553},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.11180168390274048},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.10398462414741516},{"id":"https://openalex.org/C104779481","wikidata":"https://www.wikidata.org/wiki/Q50707","display_name":"Composite number","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001499","descriptor_name":"Bayes Theorem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002247","descriptor_name":"Carbon Isotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002247","descriptor_name":"Carbon Isotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002247","descriptor_name":"Carbon Isotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009838","descriptor_name":"Oligodeoxyribonucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009838","descriptor_name":"Oligodeoxyribonucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009838","descriptor_name":"Oligodeoxyribonucleotides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011336","descriptor_name":"Probability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012985","descriptor_name":"Software Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012985","descriptor_name":"Software Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012985","descriptor_name":"Software Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/ci00060a009","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ci00060a009","pdf_url":null,"source":{"id":"https://openalex.org/S171559003","display_name":"Journal of Chemical Information and Computer Sciences","issn_l":"0095-2338","issn":["0095-2338","1520-5142"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Computer Sciences","raw_type":"journal-article"},{"id":"pmid:3235474","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3235474","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and computer sciences","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5799999833106995,"id":"https://metadata.un.org/sdg/16","display_name":"Peace, Justice and strong institutions"},{"score":0.4399999976158142,"id":"https://metadata.un.org/sdg/10","display_name":"Reduced inequalities"}],"awards":[{"id":"https://openalex.org/G8177568117","display_name":null,"funder_award_id":"RR01317","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G8491123729","display_name":null,"funder_award_id":"GM35069","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G917670889","display_name":null,"funder_award_id":"GM32691","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320319990","display_name":"National Institute for Health and Care Research","ror":"https://ror.org/0187kwz08"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3034774545","https://openalex.org/W4390542592","https://openalex.org/W2083677154","https://openalex.org/W4287269571","https://openalex.org/W2188650561","https://openalex.org/W3137735170","https://openalex.org/W2825391699","https://openalex.org/W3104584085","https://openalex.org/W2089519699","https://openalex.org/W4237728685"],"abstract_inverted_index":{"A":[0],"statistical":[1],"method,":[2],"Bayes":[3],"Maximum":[4],"Likelihood,":[5],"has":[6],"been":[7],"applied":[8],"to":[9],"the":[10,39,44,48,52,57,63,72,86],"classification":[11],"of":[12,22,35,76],"base":[13],"13C":[14],"NMR":[15],"resonances":[16],"in":[17,59,85],"DNA":[18],"oligomers.":[19],"An":[20],"accuracy":[21],"100%":[23],"for":[24,30],"carbon":[25,92],"class":[26,93],"discrimination":[27],"was":[28,54],"achieved":[29],"a":[31,68,77],"preliminary":[32],"training":[33,88],"set":[34],"four":[36,41],"oligomers":[37],"using":[38],"following":[40],"parameters:":[42],"(1)":[43],"chemical":[45,60],"shift;":[46],"(2)":[47],"temperature":[49],"at":[50],"which":[51],"spectrum":[53],"obtained;":[55],"(3)":[56],"difference":[58],"shift":[61],"from":[62],"C5":[64],"resonances;":[65],"and":[66,82],"(4)":[67],"sequence":[69],"factor":[70],"representing":[71],"neighboring":[73],"nucleotides.":[74],"Classification":[75],"fifth":[78],"oligomer,":[79],"previously":[80],"assigned":[81],"not":[83],"contained":[84],"original":[87],"set,":[89],"gave":[90],"reasonable":[91],"assignments.":[94]},"counts_by_year":[],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2016-06-24T00:00:00"}