{"id":"https://openalex.org/W2912812183","doi":"https://doi.org/10.1021/acs.jcim.8b00885","title":"Changes in Microenvironment Modulate the B- to A-DNA Transition","display_name":"Changes in Microenvironment Modulate the B- to A-DNA Transition","publication_year":2019,"publication_date":"2019-02-15","ids":{"openalex":"https://openalex.org/W2912812183","doi":"https://doi.org/10.1021/acs.jcim.8b00885","mag":"2912812183","pmid":"https://pubmed.ncbi.nlm.nih.gov/30767527"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.8b00885","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.8b00885","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080251724","display_name":"Hong Zhang","orcid":"https://orcid.org/0000-0002-3303-5109"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hong Zhang","raw_affiliation_strings":["Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Tianjin 300071, China"],"raw_orcid":"https://orcid.org/0000-0002-3303-5109","affiliations":[{"raw_affiliation_string":"Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Tianjin 300071, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058699852","display_name":"Haohao Fu","orcid":"https://orcid.org/0000-0003-0908-0046"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haohao Fu","raw_affiliation_strings":["Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Tianjin 300071, China"],"raw_orcid":"https://orcid.org/0000-0003-0908-0046","affiliations":[{"raw_affiliation_string":"Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Tianjin 300071, China","institution_ids":["https://openalex.org/I205237279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101639531","display_name":"Xueguang Shao","orcid":"https://orcid.org/0000-0001-5027-4382"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]},{"id":"https://openalex.org/I4210151209","display_name":"Collaborative Innovation Center of Chemical Science and Engineering Tianjin","ror":"https://ror.org/0225a5s12","country_code":"CN","type":"facility","lineage":["https://openalex.org/I162868743","https://openalex.org/I205237279","https://openalex.org/I4210151209"]},{"id":"https://openalex.org/I4210156066","display_name":"State Key Laboratory of Chemical Engineering","ror":"https://ror.org/05803vc71","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210156066"]},{"id":"https://openalex.org/I4391767646","display_name":"State Key Laboratory of Medicinal Chemical Biology","ror":"https://ror.org/032p70522","country_code":null,"type":"facility","lineage":["https://openalex.org/I205237279","https://openalex.org/I4391767646"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xueguang Shao","raw_affiliation_strings":["Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300071, China","Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Tianjin 300071, China","State Key Laboratory of Medicinal Chemical Biology, Tianjin 300071, China"],"raw_orcid":"https://orcid.org/0000-0001-5027-4382","affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300071, China","institution_ids":["https://openalex.org/I4210151209"]},{"raw_affiliation_string":"Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Tianjin 300071, China","institution_ids":["https://openalex.org/I205237279"]},{"raw_affiliation_string":"State Key Laboratory of Medicinal Chemical Biology, Tianjin 300071, China","institution_ids":["https://openalex.org/I4210156066","https://openalex.org/I4391767646"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114377472","display_name":"Fran\u00e7ois Dehez","orcid":"https://orcid.org/0000-0001-8076-6222"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I4387156043","display_name":"Laboratoire de Physique et Chimie Th\u00e9oriques","ror":"https://ror.org/02atkd403","country_code":null,"type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4387156043","https://openalex.org/I90183372"]},{"id":"https://openalex.org/I90183372","display_name":"Universit\u00e9 de Lorraine","ror":"https://ror.org/04vfs2w97","country_code":"FR","type":"education","lineage":["https://openalex.org/I90183372"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"Fran\u00e7ois Dehez","raw_affiliation_strings":["LPCT, UMR 7019 Universit\u00e9 de Lorraine CNRS, Vandoeuvre-l\u00e8s-Nancy F-54500, France","Laboratoire International Associ\u00e9 CNRS and University of Illinois at Urbana\u2212Champaign, Vandoeuvre-l\u00e8s-Nancy F-54506, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LPCT, UMR 7019 Universit\u00e9 de Lorraine CNRS, Vandoeuvre-l\u00e8s-Nancy F-54500, France","institution_ids":["https://openalex.org/I90183372","https://openalex.org/I1294671590","https://openalex.org/I4387156043"]},{"raw_affiliation_string":"Laboratoire International Associ\u00e9 CNRS and University of Illinois at Urbana\u2212Champaign, Vandoeuvre-l\u00e8s-Nancy F-54506, France","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1294671590"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076283101","display_name":"Christophe Chipot","orcid":"https://orcid.org/0000-0002-9122-1698"},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I157725225","display_name":"University of Illinois Urbana-Champaign","ror":"https://ror.org/047426m28","country_code":"US","type":"education","lineage":["https://openalex.org/I157725225"]},{"id":"https://openalex.org/I4387156043","display_name":"Laboratoire de Physique et Chimie Th\u00e9oriques","ror":"https://ror.org/02atkd403","country_code":null,"type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4387156043","https://openalex.org/I90183372"]},{"id":"https://openalex.org/I90183372","display_name":"Universit\u00e9 de Lorraine","ror":"https://ror.org/04vfs2w97","country_code":"FR","type":"education","lineage":["https://openalex.org/I90183372"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"Christophe Chipot","raw_affiliation_strings":["Department of Physics, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","LPCT, UMR 7019 Universit\u00e9 de Lorraine CNRS, Vandoeuvre-l\u00e8s-Nancy F-54500, France","Laboratoire International Associ\u00e9 CNRS and University of Illinois at Urbana\u2212Champaign, Vandoeuvre-l\u00e8s-Nancy F-54506, France"],"raw_orcid":"https://orcid.org/0000-0002-9122-1698","affiliations":[{"raw_affiliation_string":"Department of Physics, University of Illinois at Urbana\u2212Champaign, Urbana, Illinois 61801, United States","institution_ids":["https://openalex.org/I157725225"]},{"raw_affiliation_string":"LPCT, UMR 7019 Universit\u00e9 de Lorraine CNRS, Vandoeuvre-l\u00e8s-Nancy F-54500, France","institution_ids":["https://openalex.org/I90183372","https://openalex.org/I1294671590","https://openalex.org/I4387156043"]},{"raw_affiliation_string":"Laboratoire International Associ\u00e9 CNRS and University of Illinois at Urbana\u2212Champaign, Vandoeuvre-l\u00e8s-Nancy F-54506, France","institution_ids":["https://openalex.org/I157725225","https://openalex.org/I1294671590"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010656224","display_name":"Wensheng Cai","orcid":"https://orcid.org/0000-0002-6457-7058"},"institutions":[{"id":"https://openalex.org/I205237279","display_name":"Nankai University","ror":"https://ror.org/01y1kjr75","country_code":"CN","type":"education","lineage":["https://openalex.org/I205237279"]},{"id":"https://openalex.org/I4210151209","display_name":"Collaborative Innovation Center of Chemical Science and Engineering Tianjin","ror":"https://ror.org/0225a5s12","country_code":"CN","type":"facility","lineage":["https://openalex.org/I162868743","https://openalex.org/I205237279","https://openalex.org/I4210151209"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wensheng Cai","raw_affiliation_strings":["Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300071, China","Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Tianjin 300071, China"],"raw_orcid":"https://orcid.org/0000-0002-6457-7058","affiliations":[{"raw_affiliation_string":"Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300071, China","institution_ids":["https://openalex.org/I4210151209"]},{"raw_affiliation_string":"Research Center for Analytical Sciences, College of Chemistry, Nankai University, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Tianjin 300071, China","institution_ids":["https://openalex.org/I205237279"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5010656224"],"corresponding_institution_ids":["https://openalex.org/I205237279","https://openalex.org/I4210151209"],"apc_list":null,"apc_paid":null,"fwci":0.8548,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.72098047,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"59","issue":"5","first_page":"2324","last_page":"2330"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9941999912261963,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11582","display_name":"Nanopore and Nanochannel Transport Studies","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.7887845039367676},{"id":"https://openalex.org/keywords/transition","display_name":"Transition (genetics)","score":0.7146047353744507},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.6502659916877747},{"id":"https://openalex.org/keywords/transition-state","display_name":"Transition state","score":0.6106165051460266},{"id":"https://openalex.org/keywords/ethanol","display_name":"Ethanol","score":0.5627881288528442},{"id":"https://openalex.org/keywords/molecule","display_name":"Molecule","score":0.5433185696601868},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.5137466192245483},{"id":"https://openalex.org/keywords/chemical-physics","display_name":"Chemical physics","score":0.4628443419933319},{"id":"https://openalex.org/keywords/solvent","display_name":"Solvent","score":0.4540260434150696},{"id":"https://openalex.org/keywords/crystallography","display_name":"Crystallography","score":0.3551587462425232},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.2143213450908661},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.14219513535499573},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.10803309082984924},{"id":"https://openalex.org/keywords/catalysis","display_name":"Catalysis","score":0.0975206196308136}],"concepts":[{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.7887845039367676},{"id":"https://openalex.org/C194232998","wikidata":"https://www.wikidata.org/wiki/Q1606712","display_name":"Transition (genetics)","level":3,"score":0.7146047353744507},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6502659916877747},{"id":"https://openalex.org/C89031862","wikidata":"https://www.wikidata.org/wiki/Q906964","display_name":"Transition state","level":3,"score":0.6106165051460266},{"id":"https://openalex.org/C2780161600","wikidata":"https://www.wikidata.org/wiki/Q153","display_name":"Ethanol","level":2,"score":0.5627881288528442},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.5433185696601868},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5137466192245483},{"id":"https://openalex.org/C159467904","wikidata":"https://www.wikidata.org/wiki/Q2001702","display_name":"Chemical physics","level":1,"score":0.4628443419933319},{"id":"https://openalex.org/C2780471494","wikidata":"https://www.wikidata.org/wiki/Q146505","display_name":"Solvent","level":2,"score":0.4540260434150696},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3551587462425232},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2143213450908661},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.14219513535499573},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.10803309082984924},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0975206196308136},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000431","descriptor_name":"Ethanol","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D009690","descriptor_name":"Nucleic Acid Conformation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D044704","descriptor_name":"DNA, A-Form","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D044704","descriptor_name":"DNA, A-Form","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D044704","descriptor_name":"DNA, A-Form","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D059371","descriptor_name":"DNA, B-Form","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D059371","descriptor_name":"DNA, B-Form","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D059371","descriptor_name":"DNA, B-Form","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1021/acs.jcim.8b00885","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.8b00885","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:30767527","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30767527","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null},{"id":"pmh:oai:HAL:hal-02336347v1","is_oa":false,"landing_page_url":"https://hal.science/hal-02336347","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Chemical Information and Modeling, 2019, 59 (5), pp.2324-2330. ⟨10.1021/acs.jcim.8b00885⟩","raw_type":"Journal articles"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/6","score":0.44999998807907104,"display_name":"Clean water and sanitation"}],"awards":[{"id":"https://openalex.org/G1718626995","display_name":null,"funder_award_id":"18JCYBJC20500","funder_id":"https://openalex.org/F4320323993","funder_display_name":"Natural Science Foundation of Tianjin City"},{"id":"https://openalex.org/G4680215813","display_name":"\u9762\u5411\u8ba1\u7b97\u673a\u8f85\u52a9\u5206\u5b50\u673a\u5668\u8bbe\u8ba1\u7684\u6a21\u62df\u65b9\u6cd5\u548c\u5e94\u7528\u7814\u7a76","funder_award_id":"21773125","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7091379251","display_name":null,"funder_award_id":"201806200074","funder_id":"https://openalex.org/F4320322725","funder_display_name":"China Scholarship Council"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322725","display_name":"China Scholarship Council","ror":"https://ror.org/04atp4p48"},{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"},{"id":"https://openalex.org/F4320323993","display_name":"Natural Science Foundation of Tianjin City","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":60,"referenced_works":["https://openalex.org/W1963835420","https://openalex.org/W1964428307","https://openalex.org/W1971919524","https://openalex.org/W1974030600","https://openalex.org/W1977482735","https://openalex.org/W1978330227","https://openalex.org/W1978482484","https://openalex.org/W1979150783","https://openalex.org/W1981482769","https://openalex.org/W1983194324","https://openalex.org/W1989906072","https://openalex.org/W1990779594","https://openalex.org/W1996075279","https://openalex.org/W2004518911","https://openalex.org/W2017835622","https://openalex.org/W2019251428","https://openalex.org/W2020933397","https://openalex.org/W2027796930","https://openalex.org/W2029667189","https://openalex.org/W2030338243","https://openalex.org/W2032820551","https://openalex.org/W2033231433","https://openalex.org/W2035157039","https://openalex.org/W2035816279","https://openalex.org/W2038758364","https://openalex.org/W2038988936","https://openalex.org/W2039822621","https://openalex.org/W2050333027","https://openalex.org/W2051536237","https://openalex.org/W2052329232","https://openalex.org/W2053937805","https://openalex.org/W2054913898","https://openalex.org/W2057765314","https://openalex.org/W2058971275","https://openalex.org/W2060872117","https://openalex.org/W2063037211","https://openalex.org/W2067174909","https://openalex.org/W2074395696","https://openalex.org/W2084901693","https://openalex.org/W2090220808","https://openalex.org/W2090237155","https://openalex.org/W2090858729","https://openalex.org/W2095302421","https://openalex.org/W2100380699","https://openalex.org/W2103945336","https://openalex.org/W2106140689","https://openalex.org/W2128175348","https://openalex.org/W2150981663","https://openalex.org/W2151819925","https://openalex.org/W2204959575","https://openalex.org/W2288206553","https://openalex.org/W2322945905","https://openalex.org/W2329575826","https://openalex.org/W2346187388","https://openalex.org/W2575964962","https://openalex.org/W2620139211","https://openalex.org/W2775301394","https://openalex.org/W2885128148","https://openalex.org/W2887623770","https://openalex.org/W2887833678"],"related_works":["https://openalex.org/W4586748","https://openalex.org/W2520868764","https://openalex.org/W2415483592","https://openalex.org/W2441055957","https://openalex.org/W2334800703","https://openalex.org/W2112985449","https://openalex.org/W2040384028","https://openalex.org/W2066701252","https://openalex.org/W2419488332","https://openalex.org/W2556749675"],"abstract_inverted_index":{"B-":[0,77,109,130],"to":[1,6,9,40,63,78,110,153,173],"A-DNA":[2,79],"transition":[3,27,54,80,128],"is":[4,61,124],"known":[5],"be":[7],"sensitive":[8],"the":[10,14,48,70,76,82,96,100,108,135,142,147,156,164,189,195],"macroscopic":[11],"properties":[12],"of":[13,36,51,84,98,104,134,144,160,184,188,191],"solution,":[15],"such":[16,66],"as":[17],"salt":[18],"and":[19,81,131,158,167,187],"ethanol":[20,93,145],"concentrations.":[21,94],"Microenvironmental":[22],"effects":[23],"on":[24],"DNA":[25,38,53,105,138,185],"conformational":[26,196],"have":[28],"been":[29],"broadly":[30],"studied.":[31],"Providing":[32],"an":[33],"intuitive":[34],"picture":[35],"how":[37],"responds":[39],"environmental":[41],"changes":[42,106],"is,":[43],"however,":[44],"still":[45],"needed.":[46],"Analyzing":[47],"chemical":[49,122],"equilibrium":[50,123],"B-to-A":[52,175],"at":[55],"critical":[56],"concentrations,":[57],"employing":[58],"explicit-solvent":[59],"simulations,":[60],"envisioned":[62],"help":[64],"understand":[65],"microenvironmental":[67],"effects.":[68],"In":[69,118],"present":[71,178],"study,":[72],"free-energy":[73,182],"calculations":[74],"characterizing":[75],"distribution":[83],"cations":[85,148],"were":[86],"carried":[87],"out":[88],"in":[89,112,194],"solvents":[90],"with":[91,114,141],"different":[92],"With":[95],"addition":[97],"ethanol,":[99,120],"most":[101],"stable":[102],"structure":[103],"from":[107],"A-form,":[111],"agreement":[113],"previous":[115],"experimental":[116],"observation.":[117],"60%":[119],"a":[121,150,174,181],"found,":[125],"showing":[126],"reversible":[127],"between":[129],"A-DNA.":[132],"Analysis":[133],"microenvironment":[136,186],"around":[137,163],"suggests":[139],"that":[140],"increase":[143],"concentration,":[146],"exhibit":[149],"significant":[151],"tendency":[152],"move":[154],"toward":[155],"backbone,":[157],"mobility":[159],"water":[161],"molecules":[162],"major":[165],"groove":[166],"backbone":[168],"decreases":[169],"gradually,":[170],"leading":[171],"eventually":[172],"transition.":[176,197],"The":[177],"results":[179],"provide":[180],"view":[183],"role":[190],"cation":[192],"motion":[193]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3}],"updated_date":"2026-06-06T09:05:17.133730","created_date":"2025-10-10T00:00:00"}