{"id":"https://openalex.org/W2912444003","doi":"https://doi.org/10.1021/acs.jcim.8b00847","title":"Radical Scavenging Activity of Natural-Based Cassaine Diterpenoid Amides and Amines","display_name":"Radical Scavenging Activity of Natural-Based Cassaine Diterpenoid Amides and Amines","publication_year":2019,"publication_date":"2019-01-25","ids":{"openalex":"https://openalex.org/W2912444003","doi":"https://doi.org/10.1021/acs.jcim.8b00847","mag":"2912444003","pmid":"https://pubmed.ncbi.nlm.nih.gov/30681326"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.8b00847","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.8b00847","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034895983","display_name":"Th\u1ecb Chinh Ngo","orcid":"https://orcid.org/0000-0002-8206-5996"},"institutions":[{"id":"https://openalex.org/I170238339","display_name":"Duy Tan University","ror":"https://ror.org/05ezss144","country_code":"VN","type":"education","lineage":["https://openalex.org/I170238339"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Thi Chinh Ngo","raw_affiliation_strings":["Institute of Research and Development, Duy Tan University, 03 Quang Trung, Danang, 550000, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Research and Development, Duy Tan University, 03 Quang Trung, Danang, 550000, Vietnam","institution_ids":["https://openalex.org/I170238339"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111382126","display_name":"Thi Hau Nguyen","orcid":null},"institutions":[{"id":"https://openalex.org/I170238339","display_name":"Duy Tan University","ror":"https://ror.org/05ezss144","country_code":"VN","type":"education","lineage":["https://openalex.org/I170238339"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Thi Hau Nguyen","raw_affiliation_strings":["Faculty of Pharmacy, Duy Tan University, 03 Quang Trung, Danang, 550000, Vietnam"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, Duy Tan University, 03 Quang Trung, Danang, 550000, Vietnam","institution_ids":["https://openalex.org/I170238339"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082824466","display_name":"Duy Quang Dao","orcid":"https://orcid.org/0000-0003-0896-5168"},"institutions":[{"id":"https://openalex.org/I170238339","display_name":"Duy Tan University","ror":"https://ror.org/05ezss144","country_code":"VN","type":"education","lineage":["https://openalex.org/I170238339"]}],"countries":["VN"],"is_corresponding":true,"raw_author_name":"Duy Quang Dao","raw_affiliation_strings":["Institute of Research and Development, Duy Tan University, 03 Quang Trung, Danang, 550000, Vietnam"],"raw_orcid":"https://orcid.org/0000-0003-0896-5168","affiliations":[{"raw_affiliation_string":"Institute of Research and Development, Duy Tan University, 03 Quang Trung, Danang, 550000, Vietnam","institution_ids":["https://openalex.org/I170238339"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5082824466"],"corresponding_institution_ids":["https://openalex.org/I170238339"],"apc_list":null,"apc_paid":null,"fwci":3.2938,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.91192029,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"59","issue":"2","first_page":"766","last_page":"776"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13921","display_name":"Biological Stains and Phytochemicals","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13921","display_name":"Biological Stains and Phytochemicals","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13013","display_name":"Free Radicals and Antioxidants","score":0.9850000143051147,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.9836999773979187,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.8566367030143738},{"id":"https://openalex.org/keywords/bond-dissociation-energy","display_name":"Bond-dissociation energy","score":0.737494707107544},{"id":"https://openalex.org/keywords/hydrogen-atom-abstraction","display_name":"Hydrogen atom abstraction","score":0.6320372819900513},{"id":"https://openalex.org/keywords/radical","display_name":"Radical","score":0.5407770276069641},{"id":"https://openalex.org/keywords/electron-transfer","display_name":"Electron transfer","score":0.49181845784187317},{"id":"https://openalex.org/keywords/density-functional-theory","display_name":"Density functional theory","score":0.46110305190086365},{"id":"https://openalex.org/keywords/proton-affinity","display_name":"Proton affinity","score":0.4457300305366516},{"id":"https://openalex.org/keywords/adduct","display_name":"Adduct","score":0.4387241303920746},{"id":"https://openalex.org/keywords/hydrogen-bond","display_name":"Hydrogen bond","score":0.4372912049293518},{"id":"https://openalex.org/keywords/computational-chemistry","display_name":"Computational chemistry","score":0.39857515692710876},{"id":"https://openalex.org/keywords/molecule","display_name":"Molecule","score":0.37714385986328125},{"id":"https://openalex.org/keywords/medicinal-chemistry","display_name":"Medicinal chemistry","score":0.37395238876342773},{"id":"https://openalex.org/keywords/photochemistry","display_name":"Photochemistry","score":0.30960559844970703},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.2856276035308838}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.8566367030143738},{"id":"https://openalex.org/C62396407","wikidata":"https://www.wikidata.org/wiki/Q863696","display_name":"Bond-dissociation energy","level":3,"score":0.737494707107544},{"id":"https://openalex.org/C81022585","wikidata":"https://www.wikidata.org/wiki/Q5954884","display_name":"Hydrogen atom abstraction","level":3,"score":0.6320372819900513},{"id":"https://openalex.org/C139066938","wikidata":"https://www.wikidata.org/wiki/Q185056","display_name":"Radical","level":2,"score":0.5407770276069641},{"id":"https://openalex.org/C123669783","wikidata":"https://www.wikidata.org/wiki/Q902898","display_name":"Electron transfer","level":2,"score":0.49181845784187317},{"id":"https://openalex.org/C152365726","wikidata":"https://www.wikidata.org/wiki/Q1048589","display_name":"Density functional theory","level":2,"score":0.46110305190086365},{"id":"https://openalex.org/C53323650","wikidata":"https://www.wikidata.org/wiki/Q1118362","display_name":"Proton affinity","level":4,"score":0.4457300305366516},{"id":"https://openalex.org/C108204754","wikidata":"https://www.wikidata.org/wiki/Q353392","display_name":"Adduct","level":2,"score":0.4387241303920746},{"id":"https://openalex.org/C112887158","wikidata":"https://www.wikidata.org/wiki/Q169324","display_name":"Hydrogen bond","level":3,"score":0.4372912049293518},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.39857515692710876},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.37714385986328125},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.37395238876342773},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.30960559844970703},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2856276035308838},{"id":"https://openalex.org/C145148216","wikidata":"https://www.wikidata.org/wiki/Q36496","display_name":"Ion","level":2,"score":0.0},{"id":"https://openalex.org/C30095370","wikidata":"https://www.wikidata.org/wiki/Q899488","display_name":"Protonation","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000077318","descriptor_name":"Density Functional Theory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077318","descriptor_name":"Density Functional Theory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077318","descriptor_name":"Density Functional Theory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000470","descriptor_name":"Alkaloids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000470","descriptor_name":"Alkaloids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000470","descriptor_name":"Alkaloids","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000577","descriptor_name":"Amides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000577","descriptor_name":"Amides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000577","descriptor_name":"Amides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000588","descriptor_name":"Amines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000588","descriptor_name":"Amines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000588","descriptor_name":"Amines","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004224","descriptor_name":"Diterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004224","descriptor_name":"Diterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004224","descriptor_name":"Diterpenes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016166","descriptor_name":"Free Radical Scavengers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016166","descriptor_name":"Free Radical Scavengers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016166","descriptor_name":"Free Radical Scavengers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D045784","descriptor_name":"Abietanes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D045784","descriptor_name":"Abietanes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D045784","descriptor_name":"Abietanes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/acs.jcim.8b00847","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.8b00847","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:30681326","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30681326","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1024237197","https://openalex.org/W1485256456","https://openalex.org/W1494837992","https://openalex.org/W1974252577","https://openalex.org/W1998162823","https://openalex.org/W2001451174","https://openalex.org/W2008309709","https://openalex.org/W2013038381","https://openalex.org/W2016887717","https://openalex.org/W2023271753","https://openalex.org/W2024361025","https://openalex.org/W2025624195","https://openalex.org/W2027262166","https://openalex.org/W2032429883","https://openalex.org/W2033952216","https://openalex.org/W2035196826","https://openalex.org/W2037459593","https://openalex.org/W2038083805","https://openalex.org/W2041888376","https://openalex.org/W2043701535","https://openalex.org/W2057980421","https://openalex.org/W2064262385","https://openalex.org/W2078899588","https://openalex.org/W2079746465","https://openalex.org/W2081643670","https://openalex.org/W2086957099","https://openalex.org/W2092678853","https://openalex.org/W2093765535","https://openalex.org/W2094449844","https://openalex.org/W2148975481","https://openalex.org/W2156279367","https://openalex.org/W2169898152","https://openalex.org/W2294310069","https://openalex.org/W2298561124","https://openalex.org/W2319007075","https://openalex.org/W2337231561","https://openalex.org/W2583515733","https://openalex.org/W2589803797","https://openalex.org/W2610734702","https://openalex.org/W2745413701","https://openalex.org/W2759140496","https://openalex.org/W2760279121","https://openalex.org/W2788175003","https://openalex.org/W2888803049","https://openalex.org/W4249841422"],"related_works":["https://openalex.org/W1970814444","https://openalex.org/W2025375659","https://openalex.org/W1963524585","https://openalex.org/W1966795621","https://openalex.org/W2093206225","https://openalex.org/W2151436003","https://openalex.org/W1983890844","https://openalex.org/W2802153411","https://openalex.org/W1949300421","https://openalex.org/W2047624477"],"abstract_inverted_index":{"The":[0,134,152,231],"radical":[1,96,113],"scavenging":[2],"capacities":[3],"of":[4,47,50,86,91,234],"four":[5,25],"new":[6,26],"cassaine":[7,27,92],"diterpenoid":[8,28],"amides":[9],"including":[10,67,97],"3\u03b2-hydroxydinorerythrosuamide":[11],"(1),":[12],"3\u03b2-acetoxydinorerythrosuamide":[13],"(2),":[14],"3\u03b2-tigloyloxydinorerythrosuamide":[15],"(3),":[16],"and":[17,24,39,75,121,132,138,144,184,188,217,247],"6\u03b1-hydroxydinorcassamide":[18],"(4)":[19],"present":[20,160],"in":[21,44,127,195],"leaf":[22],"extract":[23,46],"amines":[29],"namely":[30],"erythroformine":[31,34],"A":[32],"(5),":[33],"B":[35],"(6),":[36],"6\u03b1-hydroxy-nor-cassamine":[37],"(7),":[38],"nor-erythrosuamine":[40],"(8)":[41],"recently":[42],"identified":[43],"the":[45,48,83,128,142,157,199,204],"bark":[49],"Erythrophleum":[51],"fordii":[52],"were":[53,80,125,147],"elucidated":[54],"using":[55],"density":[56],"functional":[57],"theory":[58],"(DFT)":[59],"method.":[60],"Different":[61],"thermochemical":[62],"properties":[63],"characterizing":[64],"antioxidant":[65,162],"potential":[66,78,135],"bond":[68],"dissociation":[69],"enthalpy":[70],"(BDE),":[71],"proton":[72,108,122],"affinity":[73],"(PA),":[74],"adiabatic":[76],"ionization":[77],"(IP)":[79],"calculated":[81,148],"at":[82,149,212,222],"B3LYP/6-311G(d,p)":[84],"level":[85],"theory.":[87],"Scavenging":[88],"reaction":[89],"mechanisms":[90],"diterpenes":[93],"toward":[94],"HOO\u2022":[95],"formal":[98],"hydrogen":[99,103],"transfer":[100,105,111,119,123],"(FHT;":[101],"either":[102],"atom":[104],"(HAT)":[106],"or":[107],"coupled":[109],"electron":[110,118],"(PCET)),":[112],"adduct":[114],"formation":[115],"(RAF),":[116],"single":[117],"(SET),":[120],"(PT)":[124],"studied":[126,158,200],"gas":[129],"phase,":[130],"water,":[131],"benzene.":[133],"energy":[136],"profiles":[137],"kinetic":[139],"calculations":[140],"for":[141,209,218],"FHT":[143],"RAF":[145,185,219],"reactions":[146,190,236],"298.15":[150],"K.":[151],"results":[153],"showed":[154],"that":[155],"all":[156],"compounds":[159],"strong":[161],"activity":[163],"via":[164],"HAT":[165,183,210],"mechanism":[166],"with":[167,240],"BDEs":[168],"varying":[169],"from":[170],"69.4":[171],"to":[172,193],"77.9":[173],"kcal/mol.":[174],"While":[175],"solvents":[176],"have":[177],"only":[178],"a":[179],"slight":[180],"effect":[181],"on":[182],"mechanisms,":[186],"SET":[187],"PT":[189],"are":[191,237],"likely":[192],"occur":[194],"polar":[196],"media.":[197],"Among":[198],"compounds,":[201],"3":[202],"is":[203],"most":[205],"reactive":[206],"one":[207],"both":[208],"(H-abstraction":[211],"C7,":[213],"\u0394H":[214,227],"\u221211.3":[215],"kcal/mol)":[216,229],"(radical":[220],"addition":[221],"C13":[223],"=":[224],"C15":[225],"bond,":[226],"\u22125.2":[228],"reactions.":[230],"rate":[232],"constants":[233],"these":[235],"also":[238],"comparable":[239],"several":[241],"referenced":[242],"antioxidants":[243],"such":[244],"as":[245],"Trolox":[246],"ascorbic":[248],"acid.":[249]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":4}],"updated_date":"2026-05-23T08:51:43.019350","created_date":"2025-10-10T00:00:00"}