{"id":"https://openalex.org/W2907473220","doi":"https://doi.org/10.1021/acs.jcim.8b00685","title":"Comparative Study of Multitask Toxicity Modeling on a Broad Chemical Space","display_name":"Comparative Study of Multitask Toxicity Modeling on a Broad Chemical Space","publication_year":2018,"publication_date":"2018-12-27","ids":{"openalex":"https://openalex.org/W2907473220","doi":"https://doi.org/10.1021/acs.jcim.8b00685","mag":"2907473220","pmid":"https://pubmed.ncbi.nlm.nih.gov/30589269"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.8b00685","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.8b00685","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1021/acs.jcim.8b00685","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070076249","display_name":"Sergey Sosnin","orcid":"https://orcid.org/0000-0002-3042-7369"},"institutions":[{"id":"https://openalex.org/I125989756","display_name":"Skolkovo Institute of Science and Technology","ror":"https://ror.org/03f9nc143","country_code":"RU","type":"education","lineage":["https://openalex.org/I125989756"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Sergey Sosnin","raw_affiliation_strings":["Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Moscow 143026, Russia"],"raw_orcid":"https://orcid.org/0000-0002-3042-7369","affiliations":[{"raw_affiliation_string":"Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Moscow 143026, Russia","institution_ids":["https://openalex.org/I125989756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013500408","display_name":"Dmitry S. Karlov","orcid":"https://orcid.org/0000-0002-7194-1081"},"institutions":[{"id":"https://openalex.org/I125989756","display_name":"Skolkovo Institute of Science and Technology","ror":"https://ror.org/03f9nc143","country_code":"RU","type":"education","lineage":["https://openalex.org/I125989756"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Dmitry Karlov","raw_affiliation_strings":["Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Moscow 143026, Russia"],"raw_orcid":"https://orcid.org/0000-0002-7194-1081","affiliations":[{"raw_affiliation_string":"Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Moscow 143026, Russia","institution_ids":["https://openalex.org/I125989756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067679577","display_name":"Igor V. Tetko","orcid":"https://orcid.org/0000-0002-6855-0012"},"institutions":[{"id":"https://openalex.org/I3018134672","display_name":"Helmholtz Zentrum M\u00fcnchen","ror":"https://ror.org/00cfam450","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I3018134672"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Igor V. Tetko","raw_affiliation_strings":["Helmholtz Zentrum M\u00fcnchen\u2212Research Center for Environmental Health (GmbH), Institute of Structural Biology and BIGCHEM GmbH, Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany"],"raw_orcid":"https://orcid.org/0000-0002-6855-0012","affiliations":[{"raw_affiliation_string":"Helmholtz Zentrum M\u00fcnchen\u2212Research Center for Environmental Health (GmbH), Institute of Structural Biology and BIGCHEM GmbH, Ingolst\u00e4dter Landstra\u00dfe 1, D-85764 Neuherberg, Germany","institution_ids":["https://openalex.org/I3018134672"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014755535","display_name":"Maxim V. Fedorov","orcid":"https://orcid.org/0000-0003-3901-3565"},"institutions":[{"id":"https://openalex.org/I125989756","display_name":"Skolkovo Institute of Science and Technology","ror":"https://ror.org/03f9nc143","country_code":"RU","type":"education","lineage":["https://openalex.org/I125989756"]},{"id":"https://openalex.org/I181647926","display_name":"University of Strathclyde","ror":"https://ror.org/00n3w3b69","country_code":"GB","type":"education","lineage":["https://openalex.org/I181647926"]}],"countries":["GB","RU"],"is_corresponding":true,"raw_author_name":"Maxim V. Fedorov","raw_affiliation_strings":["Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Moscow 143026, Russia","University of Strathclyde, Department of Physics, John Anderson\rBuilding, 107 Rottenrow East, Glasgow, U.K. G40NG","University of Strathclyde, Department of Physics, John Anderson Building, 107 Rottenrow East, Glasgow, U.K. G40NG"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Skolkovo Institute of Science and Technology, Skolkovo Innovation Center, Moscow 143026, Russia","institution_ids":["https://openalex.org/I125989756"]},{"raw_affiliation_string":"University of Strathclyde, Department of Physics, John Anderson\rBuilding, 107 Rottenrow East, Glasgow, U.K. G40NG","institution_ids":["https://openalex.org/I181647926"]},{"raw_affiliation_string":"University of Strathclyde, Department of Physics, John Anderson Building, 107 Rottenrow East, Glasgow, U.K. G40NG","institution_ids":["https://openalex.org/I181647926"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5014755535","https://openalex.org/A5067679577"],"corresponding_institution_ids":["https://openalex.org/I125989756","https://openalex.org/I181647926","https://openalex.org/I3018134672"],"apc_list":null,"apc_paid":null,"fwci":9.2669,"has_fulltext":false,"cited_by_count":109,"citation_normalized_percentile":{"value":0.98420969,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"59","issue":"3","first_page":"1062","last_page":"1072"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11948","display_name":"Machine Learning in Materials Science","score":0.9800999760627747,"subfield":{"id":"https://openalex.org/subfields/2505","display_name":"Materials Chemistry"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.9739999771118164,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemical-space","display_name":"Chemical space","score":0.7754929065704346},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6521990299224854},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.6039156317710876},{"id":"https://openalex.org/keywords/multi-task-learning","display_name":"Multi-task learning","score":0.5407164096832275},{"id":"https://openalex.org/keywords/license","display_name":"License","score":0.4935835599899292},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.47768694162368774},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.4241161346435547},{"id":"https://openalex.org/keywords/transfer-of-learning","display_name":"Transfer of learning","score":0.4225567579269409},{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.40562647581100464},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.1555369794368744},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.149149090051651},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13440468907356262},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.09734848141670227}],"concepts":[{"id":"https://openalex.org/C99726746","wikidata":"https://www.wikidata.org/wiki/Q906396","display_name":"Chemical space","level":3,"score":0.7754929065704346},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6521990299224854},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.6039156317710876},{"id":"https://openalex.org/C28006648","wikidata":"https://www.wikidata.org/wiki/Q6934509","display_name":"Multi-task learning","level":3,"score":0.5407164096832275},{"id":"https://openalex.org/C2780560020","wikidata":"https://www.wikidata.org/wiki/Q79719","display_name":"License","level":2,"score":0.4935835599899292},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.47768694162368774},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.4241161346435547},{"id":"https://openalex.org/C150899416","wikidata":"https://www.wikidata.org/wiki/Q1820378","display_name":"Transfer of learning","level":2,"score":0.4225567579269409},{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.40562647581100464},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.1555369794368744},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.149149090051651},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13440468907356262},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.09734848141670227},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008962","descriptor_name":"Models, Theoretical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023381","descriptor_name":"Endpoint Determination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023381","descriptor_name":"Endpoint Determination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023381","descriptor_name":"Endpoint Determination","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023382","descriptor_name":"Toxicity Tests, Acute","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023382","descriptor_name":"Toxicity Tests, Acute","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D023382","descriptor_name":"Toxicity Tests, Acute","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1021/acs.jcim.8b00685","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.8b00685","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:30589269","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30589269","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null},{"id":"pmh:oai:opus-zb.helmholtz-muenchen.de:55347","is_oa":true,"landing_page_url":"https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=55347","pdf_url":null,"source":{"id":"https://openalex.org/S4377196115","display_name":"Site cant be reached","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J. Chem. Inf. Model. 59, 1062-1072 (2019)","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:push-zb.helmholtz-munich.de:55347","is_oa":false,"landing_page_url":"https://push-zb.helmholtz-munich.de/frontdoor.php?source_opus=55347","pdf_url":null,"source":{"id":"https://openalex.org/S7407055352","display_name":"PuSH - Publication Server of Helmholtz Zentrum M\u00fcnchen","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J. Chem. Inf. Model. 59, 1062-1072 (2019)","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1021/acs.jcim.8b00685","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.8b00685","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4699999988079071,"id":"https://metadata.un.org/sdg/4","display_name":"Quality Education"}],"awards":[{"id":"https://openalex.org/G8848312115","display_name":null,"funder_award_id":"14-43-00024","funder_id":"https://openalex.org/F4320324099","funder_display_name":"Russian Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320324099","display_name":"Russian Science Foundation","ror":"https://ror.org/03y2gwe85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":54,"referenced_works":["https://openalex.org/W1185153672","https://openalex.org/W1541037889","https://openalex.org/W1972156862","https://openalex.org/W1975875968","https://openalex.org/W1977287658","https://openalex.org/W1981801253","https://openalex.org/W1982597534","https://openalex.org/W1984639110","https://openalex.org/W1986063539","https://openalex.org/W1988037271","https://openalex.org/W1988195734","https://openalex.org/W1990302994","https://openalex.org/W1990399577","https://openalex.org/W1997355076","https://openalex.org/W2002097322","https://openalex.org/W2003554223","https://openalex.org/W2016436902","https://openalex.org/W2016752740","https://openalex.org/W2028720862","https://openalex.org/W2044834685","https://openalex.org/W2051160906","https://openalex.org/W2057563786","https://openalex.org/W2061069282","https://openalex.org/W2064176611","https://openalex.org/W2065509841","https://openalex.org/W2076727577","https://openalex.org/W2077582053","https://openalex.org/W2087661061","https://openalex.org/W2094836090","https://openalex.org/W2095705004","https://openalex.org/W2104742871","https://openalex.org/W2128879247","https://openalex.org/W2129269041","https://openalex.org/W2132201383","https://openalex.org/W2147479689","https://openalex.org/W2148797284","https://openalex.org/W2149914376","https://openalex.org/W2171830166","https://openalex.org/W2177317049","https://openalex.org/W2187089797","https://openalex.org/W2342596260","https://openalex.org/W2478815458","https://openalex.org/W2556851635","https://openalex.org/W2612060048","https://openalex.org/W2747416722","https://openalex.org/W2751756351","https://openalex.org/W2769198893","https://openalex.org/W2789816271","https://openalex.org/W2790282224","https://openalex.org/W2793572928","https://openalex.org/W2809634777","https://openalex.org/W2903198840","https://openalex.org/W2911964244","https://openalex.org/W2949117887"],"related_works":["https://openalex.org/W2821676139","https://openalex.org/W3043695725","https://openalex.org/W4382138864","https://openalex.org/W4387770285","https://openalex.org/W3022215768","https://openalex.org/W3135975972","https://openalex.org/W3016888008","https://openalex.org/W4385864216","https://openalex.org/W4387183713","https://openalex.org/W4403518771"],"abstract_inverted_index":{"Acute":[0],"toxicity":[1,24,66,85,131],"is":[2,47,56],"one":[3],"of":[4,42,63,92,95,129,140],"the":[5,50,90,127,138],"most":[6],"challenging":[7],"properties":[8],"to":[9,16,20,125],"predict":[10],"purely":[11],"with":[12],"computational":[13],"methods":[14],"due":[15],"its":[17],"direct":[18],"relationship":[19],"biological":[21],"interactions.":[22],"Moreover,":[23],"can":[25,33,121],"be":[26,34,122],"represented":[27],"by":[28],"different":[29,37,40,73],"end":[30,54],"points:":[31],"it":[32,46],"measured":[35],"for":[36,67,82,143],"species":[38],"using":[39,72],"types":[41],"administration,":[43],"etc.,":[44],"and":[45,75,78,110,133],"questionable":[48],"if":[49],"knowledge":[51],"transfer":[52],"between":[53],"points":[55],"possible.":[57],"We":[58,99],"performed":[59],"a":[60,68,83,135],"comparative":[61],"study":[62],"prediction":[64],"multitask":[65,80,102,119,141],"broad":[69],"chemical":[70],"space":[71],"descriptors":[74],"modeling":[76,103,132],"algorithms":[77],"applied":[79],"learning":[81,113,120],"large":[84],"data":[86],"set":[87],"extracted":[88],"from":[89],"Registry":[91],"Toxic":[93],"Effects":[94],"Chemical":[96],"Substances":[97],"(RTECS).":[98],"demonstrated":[100],"that":[101,118],"provides":[104],"significant":[105],"improvement":[106],"over":[107],"single-output":[108],"models":[109,148],"other":[111],"machine":[112],"methods.":[114],"Our":[115,146],"research":[116],"reveals":[117],"very":[123],"useful":[124],"improve":[126],"quality":[128],"acute":[130],"raises":[134],"discussion":[136],"about":[137],"usage":[139],"approaches":[142],"regulation":[144],"purposes.":[145],"MultiTox":[147],"are":[149],"freely":[150],"available":[151],"in":[152],"OCHEM":[153],"platform":[154],"(":[155],"ochem.eu/multitox":[156],")":[157],"under":[158],"CC-BY-NC":[159],"license.":[160]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":21},{"year":2022,"cited_by_count":14},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":1}],"updated_date":"2026-07-02T09:51:11.867554","created_date":"2025-10-10T00:00:00"}