{"id":"https://openalex.org/W2594328795","doi":"https://doi.org/10.1021/acs.jcim.6b00754","title":"Chemical Space Mimicry for Drug Discovery","display_name":"Chemical Space Mimicry for Drug Discovery","publication_year":2017,"publication_date":"2017-03-03","ids":{"openalex":"https://openalex.org/W2594328795","doi":"https://doi.org/10.1021/acs.jcim.6b00754","mag":"2594328795","pmid":"https://pubmed.ncbi.nlm.nih.gov/28257191"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.6b00754","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.6b00754","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5802964","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080449859","display_name":"William Yuan","orcid":"https://orcid.org/0000-0002-2682-0416"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["GB","US"],"is_corresponding":true,"raw_author_name":"William Yuan","raw_affiliation_strings":["Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","Trinity\rCollege, University of Oxford, Oxford OX1 3BH, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Trinity\rCollege, University of Oxford, Oxford OX1 3BH, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043864498","display_name":"Dadi Jiang","orcid":"https://orcid.org/0000-0002-0935-3908"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dadi Jiang","raw_affiliation_strings":["Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017221987","display_name":"Dhanya K. Nambiar","orcid":"https://orcid.org/0000-0002-0648-403X"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dhanya K. Nambiar","raw_affiliation_strings":["Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090643688","display_name":"Lydia P. Liew","orcid":"https://orcid.org/0000-0002-9322-2010"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]},{"id":"https://openalex.org/I4210105931","display_name":"Cancer Society of New Zealand","ror":"https://ror.org/01bk8ee93","country_code":"NZ","type":"nonprofit","lineage":["https://openalex.org/I4210105931"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Lydia P. Liew","raw_affiliation_strings":["Auckland\rCancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand"],"affiliations":[{"raw_affiliation_string":"Auckland\rCancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I4210105931","https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067234230","display_name":"Michael P. Hay","orcid":"https://orcid.org/0000-0002-7087-9087"},"institutions":[{"id":"https://openalex.org/I154130895","display_name":"University of Auckland","ror":"https://ror.org/03b94tp07","country_code":"NZ","type":"education","lineage":["https://openalex.org/I154130895"]},{"id":"https://openalex.org/I4210105931","display_name":"Cancer Society of New Zealand","ror":"https://ror.org/01bk8ee93","country_code":"NZ","type":"nonprofit","lineage":["https://openalex.org/I4210105931"]}],"countries":["NZ"],"is_corresponding":false,"raw_author_name":"Michael P. Hay","raw_affiliation_strings":["Auckland\rCancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand"],"affiliations":[{"raw_affiliation_string":"Auckland\rCancer Society Research Centre, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand","institution_ids":["https://openalex.org/I4210105931","https://openalex.org/I154130895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032010200","display_name":"Joshua Bloomstein","orcid":"https://orcid.org/0000-0002-7395-1910"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua Bloomstein","raw_affiliation_strings":["Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003346297","display_name":"Peter L. Lu","orcid":null},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter Lu","raw_affiliation_strings":["Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083327006","display_name":"Brandon E. Turner","orcid":"https://orcid.org/0000-0002-8653-7524"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brandon Turner","raw_affiliation_strings":["Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013860869","display_name":"Quynh\u2010Thu Le","orcid":"https://orcid.org/0000-0002-3682-1439"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Quynh-Thu Le","raw_affiliation_strings":["Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027340494","display_name":"Robert Tibshirani","orcid":"https://orcid.org/0000-0003-0553-5090"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Tibshirani","raw_affiliation_strings":["Department of Statistics, Stanford University, Stanford, California 94305, United States"],"affiliations":[{"raw_affiliation_string":"Department of Statistics, Stanford University, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083763463","display_name":"Purvesh Khatri","orcid":"https://orcid.org/0000-0002-4143-4708"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Purvesh Khatri","raw_affiliation_strings":["Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","Institute for Immunity, Transplantation, and Infection & Division of Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, United States"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]},{"raw_affiliation_string":"Institute for Immunity, Transplantation, and Infection & Division of Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061350773","display_name":"Mark G. Moloney","orcid":"https://orcid.org/0000-0002-4440-3632"},"institutions":[{"id":"https://openalex.org/I40120149","display_name":"University of Oxford","ror":"https://ror.org/052gg0110","country_code":"GB","type":"education","lineage":["https://openalex.org/I40120149"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Mark G. Moloney","raw_affiliation_strings":["Chemistry\rResearch Laboratory, University of Oxford, Oxford OX1 3TA, United Kingdom"],"affiliations":[{"raw_affiliation_string":"Chemistry\rResearch Laboratory, University of Oxford, Oxford OX1 3TA, United Kingdom","institution_ids":["https://openalex.org/I40120149"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071185138","display_name":"Albert C. Koong","orcid":"https://orcid.org/0000-0001-9824-1643"},"institutions":[{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Albert C. Koong","raw_affiliation_strings":["Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States"],"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California 94305, United States","institution_ids":["https://openalex.org/I97018004"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":13,"corresponding_author_ids":["https://openalex.org/A5080449859"],"corresponding_institution_ids":["https://openalex.org/I40120149","https://openalex.org/I97018004"],"apc_list":null,"apc_paid":null,"fwci":8.5332,"has_fulltext":false,"cited_by_count":112,"citation_normalized_percentile":{"value":0.98145763,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":100},"biblio":{"volume":"57","issue":"4","first_page":"875","last_page":"882"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.9866999983787537,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.978600025177002,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chemical-space","display_name":"Chemical space","score":0.9240651726722717},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.7609128952026367},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.583494246006012},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.5508779883384705},{"id":"https://openalex.org/keywords/mimicry","display_name":"Mimicry","score":0.5142104625701904},{"id":"https://openalex.org/keywords/space","display_name":"Space (punctuation)","score":0.49942660331726074},{"id":"https://openalex.org/keywords/molecular-mimicry","display_name":"Molecular mimicry","score":0.4811733663082123},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.44785597920417786},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.42286744713783264},{"id":"https://openalex.org/keywords/small-molecule","display_name":"Small molecule","score":0.4181406497955322},{"id":"https://openalex.org/keywords/combinatorial-chemistry","display_name":"Combinatorial chemistry","score":0.4029013514518738},{"id":"https://openalex.org/keywords/nanotechnology","display_name":"Nanotechnology","score":0.32072511315345764},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2646377682685852},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.20254594087600708},{"id":"https://openalex.org/keywords/materials-science","display_name":"Materials science","score":0.1613861620426178},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.08143424987792969}],"concepts":[{"id":"https://openalex.org/C99726746","wikidata":"https://www.wikidata.org/wiki/Q906396","display_name":"Chemical space","level":3,"score":0.9240651726722717},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.7609128952026367},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.583494246006012},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5508779883384705},{"id":"https://openalex.org/C7863114","wikidata":"https://www.wikidata.org/wiki/Q192627","display_name":"Mimicry","level":2,"score":0.5142104625701904},{"id":"https://openalex.org/C2778572836","wikidata":"https://www.wikidata.org/wiki/Q380933","display_name":"Space (punctuation)","level":2,"score":0.49942660331726074},{"id":"https://openalex.org/C2777119779","wikidata":"https://www.wikidata.org/wiki/Q963278","display_name":"Molecular mimicry","level":3,"score":0.4811733663082123},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.44785597920417786},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.42286744713783264},{"id":"https://openalex.org/C161624437","wikidata":"https://www.wikidata.org/wiki/Q1988322","display_name":"Small molecule","level":2,"score":0.4181406497955322},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.4029013514518738},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.32072511315345764},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2646377682685852},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20254594087600708},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.1613861620426178},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.08143424987792969},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D040301","descriptor_name":"Vascular Endothelial Growth Factor Receptor-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D040301","descriptor_name":"Vascular Endothelial Growth Factor Receptor-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D040301","descriptor_name":"Vascular Endothelial Growth Factor Receptor-2","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1021/acs.jcim.6b00754","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.6b00754","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:28257191","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28257191","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null},{"id":"pmh:oai:ora.ox.ac.uk:uuid:6e7cbdb8-045b-4c1d-80de-4e2d6f3e3a6b","is_oa":false,"landing_page_url":"https://ora.ox.ac.uk/objects/uuid:6e7cbdb8-045b-4c1d-80de-4e2d6f3e3a6b","pdf_url":null,"source":{"id":"https://openalex.org/S4306402636","display_name":"Oxford University Research Archive (ORA) (University of Oxford)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I40120149","host_organization_name":"University of Oxford","host_organization_lineage":["https://openalex.org/I40120149"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Journal article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5802964","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5802964","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Chem Inf Model","raw_type":"Text"},{"id":"pmh:oai:researchspace.auckland.ac.nz:2292/34379","is_oa":false,"landing_page_url":"https://hdl.handle.net/2292/34379","pdf_url":null,"source":{"id":"https://openalex.org/S7407055463","display_name":"ResearchSpace (University of Auckland)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I154130895","host_organization_name":"University of Auckland","host_organization_lineage":["https://openalex.org/I154130895"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:5802964","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5802964","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Chem Inf Model","raw_type":"Text"},"sustainable_development_goals":[{"score":0.4399999976158142,"display_name":"Quality Education","id":"https://metadata.un.org/sdg/4"}],"awards":[{"id":"https://openalex.org/G3657929139","display_name":null,"funder_award_id":"P01 CA67166","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":12,"referenced_works":["https://openalex.org/W625755886","https://openalex.org/W1982792699","https://openalex.org/W1990670707","https://openalex.org/W2019824588","https://openalex.org/W2032584297","https://openalex.org/W2096864392","https://openalex.org/W2110791536","https://openalex.org/W2128966273","https://openalex.org/W2159887157","https://openalex.org/W2169678694","https://openalex.org/W2197008132","https://openalex.org/W2730223999"],"related_works":["https://openalex.org/W2081926413","https://openalex.org/W2080835595","https://openalex.org/W2973074952","https://openalex.org/W2096139282","https://openalex.org/W4283395020","https://openalex.org/W2043558654","https://openalex.org/W4320732452","https://openalex.org/W135095951","https://openalex.org/W4286980196","https://openalex.org/W4385588199"],"abstract_inverted_index":{"We":[0],"describe":[1],"a":[2,22],"new":[3],"library":[4],"generation":[5],"method,":[6],"Machine-based":[7],"Identification":[8],"of":[9,18,32,50,53,70,79,86],"Molecules":[10],"Inside":[11],"Characterized":[12],"Space":[13],"(MIMICS),":[14],"that":[15],"generates":[16],"sets":[17],"molecules":[19],"inspired":[20],"by":[21],"text-based":[23],"input.":[24],"MIMICS-generated":[25,41],"libraries":[26],"were":[27,43],"found":[28,44],"to":[29,45],"preserve":[30],"distributions":[31],"properties":[33],"while":[34],"simultaneously":[35],"increasing":[36],"structural":[37],"diversity.":[38],"Newly":[39],"identified":[40],"compounds":[42],"be":[46],"bioactive":[47],"as":[48],"inhibitors":[49],"specific":[51],"components":[52],"the":[54,60,68,83],"unfolded":[55],"protein":[56],"response":[57],"(UPR)":[58],"and":[59],"VEGFR2":[61],"pathway":[62],"in":[63],"cell-based":[64],"assays,":[65],"thus":[66],"confirming":[67],"applicability":[69],"this":[71],"methodology":[72],"toward":[73],"drug":[74],"design":[75],"applications.":[76],"Wider":[77],"application":[78],"MIMICS":[80],"could":[81],"facilitate":[82],"efficient":[84],"utilization":[85],"chemical":[87],"space.":[88]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":15},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":21},{"year":2020,"cited_by_count":18},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}