{"id":"https://openalex.org/W4411430064","doi":"https://doi.org/10.1021/acs.jcim.5c00600","title":"Optimal Descriptor Subset Search via Chemical Information and Target Activity-Guided Algorithm for Antimicrobial Peptide Prediction","display_name":"Optimal Descriptor Subset Search via Chemical Information and Target Activity-Guided Algorithm for Antimicrobial Peptide Prediction","publication_year":2025,"publication_date":"2025-06-18","ids":{"openalex":"https://openalex.org/W4411430064","doi":"https://doi.org/10.1021/acs.jcim.5c00600","pmid":"https://pubmed.ncbi.nlm.nih.gov/40528473"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.5c00600","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.5c00600","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1021/acs.jcim.5c00600","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040020151","display_name":"Luis A. Garc\u00eda\u2010Gonz\u00e1lez","orcid":"https://orcid.org/0000-0003-4021-3345"},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Luis A. Garc\u00eda-Gonz\u00e1lez","raw_affiliation_strings":["Centro de Nanociencias y Nanotecnolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Km. 107 Carretera Tijuana-Ensenada, Ensenada, Baja California C. P. 22860, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Centro de Nanociencias y Nanotecnolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Km. 107 Carretera Tijuana-Ensenada, Ensenada, Baja California C. P. 22860, M\u00e9xico","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015398632","display_name":"Yovani Marrero\u2010Ponce","orcid":"https://orcid.org/0000-0003-2721-1142"},"institutions":[{"id":"https://openalex.org/I86613570","display_name":"Universidad Panamericana","ror":"https://ror.org/01n1q0h77","country_code":"MX","type":"education","lineage":["https://openalex.org/I86613570"]},{"id":"https://openalex.org/I69094615","display_name":"Universidad San Francisco de Quito","ror":"https://ror.org/01r2c3v86","country_code":"EC","type":"education","lineage":["https://openalex.org/I69094615"]}],"countries":["EC","MX"],"is_corresponding":false,"raw_author_name":"Yovani Marrero-Ponce","raw_affiliation_strings":["Facultad de Ingenier\u00eda. Universidad Panamericana. Augusto Rodin No. 498, Insurgentes Mixcoac, Benito Ju\u00e1rez, Ciudad de M\u00e9xico 03920, M\u00e9xico","Grupo de Medicina Molecular y Traslacional (MeM&T), Colegio de Ciencias de la Salud (COCSA), Escuela de Medicina, Edificio de Especialidades M\u00e9dicas; Diego de Robles y v\u00eda Interoce\u00e1nica","Universidad San Francisco de Quito (USFQ)"],"affiliations":[{"raw_affiliation_string":"Facultad de Ingenier\u00eda. Universidad Panamericana. Augusto Rodin No. 498, Insurgentes Mixcoac, Benito Ju\u00e1rez, Ciudad de M\u00e9xico 03920, M\u00e9xico","institution_ids":["https://openalex.org/I86613570"]},{"raw_affiliation_string":"Grupo de Medicina Molecular y Traslacional (MeM&T), Colegio de Ciencias de la Salud (COCSA), Escuela de Medicina, Edificio de Especialidades M\u00e9dicas; Diego de Robles y v\u00eda Interoce\u00e1nica","institution_ids":[]},{"raw_affiliation_string":"Universidad San Francisco de Quito (USFQ)","institution_ids":["https://openalex.org/I69094615"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008729002","display_name":"C\u00e9sar R. Garc\u00eda\u2010Jacas","orcid":"https://orcid.org/0000-0002-3962-7658"},"institutions":[{"id":"https://openalex.org/I4210090124","display_name":"Tecnol\u00f3gico Nacional de M\u00e9xico","ror":"https://ror.org/00davry38","country_code":"MX","type":"funder","lineage":["https://openalex.org/I1302736544","https://openalex.org/I4210090124","https://openalex.org/I4413696010"]},{"id":"https://openalex.org/I18524911","display_name":"Instituto Tecnol\u00f3gico de M\u00e9rida","ror":"https://ror.org/01af24v42","country_code":"MX","type":"education","lineage":["https://openalex.org/I18524911"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"C\u00e9sar R. Garc\u00eda-Jacas","raw_affiliation_strings":["Investigador por M\u00e9xico, Secretar\u00eda de Ciencia, Humanidades","Tecnolog\u00eda e Innovaci\u00f3n (Secihti)","Tecnol\u00f3gico Nacional de M\u00e9xico, Instituto Tecnol\u00f3gico de M\u00e9rida, Unidad de Posgrado e Investigaci\u00f3n, Av. Tecnol\u00f3gico, Km. 4.5 S/N, M\u00e9rida 97000, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Investigador por M\u00e9xico, Secretar\u00eda de Ciencia, Humanidades","institution_ids":[]},{"raw_affiliation_string":"Tecnolog\u00eda e Innovaci\u00f3n (Secihti)","institution_ids":[]},{"raw_affiliation_string":"Tecnol\u00f3gico Nacional de M\u00e9xico, Instituto Tecnol\u00f3gico de M\u00e9rida, Unidad de Posgrado e Investigaci\u00f3n, Av. Tecnol\u00f3gico, Km. 4.5 S/N, M\u00e9rida 97000, M\u00e9xico","institution_ids":["https://openalex.org/I18524911","https://openalex.org/I4210090124"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5118334267","display_name":"Sergio A. Aguila Puentes","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sergio A. Aguila Puentes","raw_affiliation_strings":["Centro de Nanociencias y Nanotecnolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Km. 107 Carretera Tijuana-Ensenada, Ensenada, Baja California C. P. 22860, M\u00e9xico"],"affiliations":[{"raw_affiliation_string":"Centro de Nanociencias y Nanotecnolog\u00eda, Universidad Nacional Aut\u00f3noma de M\u00e9xico, Km. 107 Carretera Tijuana-Ensenada, Ensenada, Baja California C. P. 22860, M\u00e9xico","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5040020151"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2582,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.81127709,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"65","issue":"13","first_page":"6621","last_page":"6631"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.9988999962806702,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9943000078201294,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leverage","display_name":"Leverage (statistics)","score":0.7239920496940613},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7066518068313599},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6126605272293091},{"id":"https://openalex.org/keywords/quantitative-structure\u2013activity-relationship","display_name":"Quantitative structure\u2013activity relationship","score":0.5757808685302734},{"id":"https://openalex.org/keywords/discriminative-model","display_name":"Discriminative model","score":0.5663043260574341},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5109935998916626},{"id":"https://openalex.org/keywords/metric","display_name":"Metric (unit)","score":0.5107691287994385},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.4398171305656433},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.42430180311203003},{"id":"https://openalex.org/keywords/curse-of-dimensionality","display_name":"Curse of dimensionality","score":0.42154577374458313},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.35455745458602905},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.08319234848022461}],"concepts":[{"id":"https://openalex.org/C153083717","wikidata":"https://www.wikidata.org/wiki/Q6535263","display_name":"Leverage (statistics)","level":2,"score":0.7239920496940613},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7066518068313599},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6126605272293091},{"id":"https://openalex.org/C164126121","wikidata":"https://www.wikidata.org/wiki/Q766383","display_name":"Quantitative structure\u2013activity relationship","level":2,"score":0.5757808685302734},{"id":"https://openalex.org/C97931131","wikidata":"https://www.wikidata.org/wiki/Q5282087","display_name":"Discriminative model","level":2,"score":0.5663043260574341},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5109935998916626},{"id":"https://openalex.org/C176217482","wikidata":"https://www.wikidata.org/wiki/Q860554","display_name":"Metric (unit)","level":2,"score":0.5107691287994385},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.4398171305656433},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.42430180311203003},{"id":"https://openalex.org/C111030470","wikidata":"https://www.wikidata.org/wiki/Q1430460","display_name":"Curse of dimensionality","level":2,"score":0.42154577374458313},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.35455745458602905},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.08319234848022461},{"id":"https://openalex.org/C21547014","wikidata":"https://www.wikidata.org/wiki/Q1423657","display_name":"Operations management","level":1,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000089882","descriptor_name":"Antimicrobial Peptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000089882","descriptor_name":"Antimicrobial Peptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000089882","descriptor_name":"Antimicrobial Peptides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000089882","descriptor_name":"Antimicrobial Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000089882","descriptor_name":"Antimicrobial Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000089882","descriptor_name":"Antimicrobial Peptides","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D021281","descriptor_name":"Quantitative Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021281","descriptor_name":"Quantitative Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021281","descriptor_name":"Quantitative Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1021/acs.jcim.5c00600","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.5c00600","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:40528473","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40528473","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:12264963","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12264963","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Chem Inf Model","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1021/acs.jcim.5c00600","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.5c00600","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.4099999964237213}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W1500895378","https://openalex.org/W1514048016","https://openalex.org/W1978914444","https://openalex.org/W2008947010","https://openalex.org/W2042675496","https://openalex.org/W2623671274","https://openalex.org/W2899274556","https://openalex.org/W2912109185","https://openalex.org/W2912500072","https://openalex.org/W2914933231","https://openalex.org/W2953705189","https://openalex.org/W2982442538","https://openalex.org/W3038563735","https://openalex.org/W3094421290","https://openalex.org/W3094704314","https://openalex.org/W3134163647","https://openalex.org/W3150808126","https://openalex.org/W3172728545","https://openalex.org/W3178663131","https://openalex.org/W3205595869","https://openalex.org/W3217372366","https://openalex.org/W4213430678","https://openalex.org/W4248072700","https://openalex.org/W4304114151","https://openalex.org/W4315567700","https://openalex.org/W4323654525","https://openalex.org/W4327550249","https://openalex.org/W4386022032","https://openalex.org/W4388885402","https://openalex.org/W4392162030","https://openalex.org/W4392956895","https://openalex.org/W4396560726","https://openalex.org/W4396664948","https://openalex.org/W4399497299","https://openalex.org/W4402965891","https://openalex.org/W4404473617","https://openalex.org/W4406066491"],"related_works":["https://openalex.org/W2382340815","https://openalex.org/W1972650408","https://openalex.org/W2551736466","https://openalex.org/W1997566113","https://openalex.org/W3189652131","https://openalex.org/W2908740012","https://openalex.org/W1967793880","https://openalex.org/W2792066564","https://openalex.org/W1186905254","https://openalex.org/W2898703579"],"abstract_inverted_index":{"Antimicrobial":[0],"peptides":[1],"(AMPs)":[2],"have":[3,24],"emerged":[4],"as":[5,103],"a":[6,204,230],"promising":[7],"alternative":[8],"to":[9,13,35,150,170,196,218,240],"conventional":[10],"drugs":[11],"due":[12],"their":[14],"potential":[15],"applications":[16],"in":[17,173],"combating":[18],"multidrug-resistant":[19],"pathogens.":[20],"Various":[21],"computational":[22,224],"approaches":[23,198],"been":[25,58],"developed":[26],"for":[27,155,226,244],"AMP":[28,64,156,227,249],"prediction,":[29],"ranging":[30],"from":[31,52],"shallow":[32,44,68],"learning":[33,38,45,69],"methods":[34],"advanced":[36],"deep":[37],"techniques.":[39],"Additionally,":[40],"the":[41,61,73,90,112,118,125,146,162,186,219],"performance":[42,62,192],"of":[43,63,75,124,148,221],"models":[46,55,65,130,175,183],"based":[47,66,184],"on":[48,67,72,132,185],"self-learning":[49],"features":[50],"derived":[51,77],"protein":[53],"language":[54],"has":[56],"recently":[57],"studied.":[59],"However,":[60],"strongly":[70],"depends":[71],"quality":[74],"descriptors":[76,135,163,187],"via":[78],"manual":[79],"feature":[80,106],"engineering,":[81],"which":[82],"may":[83],"miss":[84],"crucial":[85],"information":[86,168],"by":[87,117,165,189],"assuming":[88],"that":[89,110,161],"initial":[91],"descriptor":[92,114,153,246],"set":[93,115],"fully":[94],"captures":[95],"relevant":[96],"information.":[97],"The":[98,181],"AExOp-DCS":[99,133,149,166,190],"algorithm":[100],"was":[101],"introduced":[102],"an":[104],"automatic":[105],"domain":[107],"optimization":[108],"method":[109],"identifies":[111],"\"optimal\"":[113],"driven":[116],"chemical":[119],"structure":[120],"and":[121,248],"biological":[122],"activity":[123],"compounds":[126],"under":[127],"study.":[128],"QSAR":[129],"built":[131],"optimized":[134],"outperform":[136],"those":[137,171],"using":[138],"nonoptimized":[139],"sets.":[140],"In":[141],"this":[142,215],"study,":[143],"we":[144],"explore":[145],"use":[147],"identify":[151],"optimal":[152],"subsets":[154],"modeling.":[157],"Experimental":[158],"results":[159],"show":[160],"returned":[164,188],"contain":[167],"comparable":[169,195],"used":[172],"top-performing":[174],"while":[176,199],"exhibiting":[177],"higher":[178],"discriminative":[179],"capacity.":[180],"generated":[182],"achieved":[191],"metric":[193],"values":[194],"state-of-the-art":[197],"utilizing":[200],"fewer":[201],"descriptors,":[202],"suggesting":[203],"more":[205,222],"efficient":[206,223],"modeling":[207],"process.":[208],"By":[209],"reducing":[210],"dimensionality":[211],"without":[212],"sacrificing":[213],"accuracy,":[214],"approach":[216],"contributes":[217],"development":[220],"pipelines":[225],"discovery.":[228],"Finally,":[229],"Java":[231],"software":[232],"called":[233],"AExOp-DCS-SEQ":[234],"is":[235],"freely":[236],"available,":[237],"enabling":[238],"researchers":[239],"leverage":[241],"its":[242],"capabilities":[243],"peptide":[245],"search":[247],"classification":[250],"tasks.":[251]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}