{"id":"https://openalex.org/W2217269832","doi":"https://doi.org/10.1021/acs.jcim.5b00544","title":"Molecular Rift: Virtual Reality for Drug Designers","display_name":"Molecular Rift: Virtual Reality for Drug Designers","publication_year":2015,"publication_date":"2015-11-02","ids":{"openalex":"https://openalex.org/W2217269832","doi":"https://doi.org/10.1021/acs.jcim.5b00544","mag":"2217269832","pmid":"https://pubmed.ncbi.nlm.nih.gov/26558887"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.5b00544","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.5b00544","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003366096","display_name":"Magnus Norrby","orcid":null},"institutions":[{"id":"https://openalex.org/I4210143795","display_name":"AstraZeneca (Sweden)","ror":"https://ror.org/04wwrrg31","country_code":"SE","type":"company","lineage":["https://openalex.org/I105036370","https://openalex.org/I4210143795"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Magnus Norrby","raw_affiliation_strings":["Department\rof Medicinal Chemistry, CVMD iMed, AstraZeneca, S-43183 M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Medicinal Chemistry, CVMD iMed, AstraZeneca, S-43183 M\u00f6lndal, Sweden","institution_ids":["https://openalex.org/I4210143795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042738116","display_name":"Christoph Grebner","orcid":"https://orcid.org/0000-0001-5301-1078"},"institutions":[{"id":"https://openalex.org/I4210143795","display_name":"AstraZeneca (Sweden)","ror":"https://ror.org/04wwrrg31","country_code":"SE","type":"company","lineage":["https://openalex.org/I105036370","https://openalex.org/I4210143795"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Christoph Grebner","raw_affiliation_strings":["Department\rof Medicinal Chemistry, CVMD iMed, AstraZeneca, S-43183 M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Medicinal Chemistry, CVMD iMed, AstraZeneca, S-43183 M\u00f6lndal, Sweden","institution_ids":["https://openalex.org/I4210143795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019634111","display_name":"Joakim Eriksson","orcid":"https://orcid.org/0000-0001-7257-4386"},"institutions":[{"id":"https://openalex.org/I187531555","display_name":"Lund University","ror":"https://ror.org/012a77v79","country_code":"SE","type":"education","lineage":["https://openalex.org/I187531555"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Joakim Eriksson","raw_affiliation_strings":["\u2021 Department of Computer Sciences and \u00a7 Department of Design Sciences, Lund University, S-223 62 Lund, Sweden","Ergonomics and Aerosol Technology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u2021 Department of Computer Sciences and \u00a7 Department of Design Sciences, Lund University, S-223 62 Lund, Sweden","institution_ids":["https://openalex.org/I187531555"]},{"raw_affiliation_string":"Ergonomics and Aerosol Technology","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088965681","display_name":"Jonas Bostr\u00f6m","orcid":"https://orcid.org/0000-0002-9719-9137"},"institutions":[{"id":"https://openalex.org/I4210143795","display_name":"AstraZeneca (Sweden)","ror":"https://ror.org/04wwrrg31","country_code":"SE","type":"company","lineage":["https://openalex.org/I105036370","https://openalex.org/I4210143795"]}],"countries":["SE"],"is_corresponding":true,"raw_author_name":"Jonas Bostr\u00f6m","raw_affiliation_strings":["Department\rof Medicinal Chemistry, CVMD iMed, AstraZeneca, S-43183 M\u00f6lndal, Sweden"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department\rof Medicinal Chemistry, CVMD iMed, AstraZeneca, S-43183 M\u00f6lndal, Sweden","institution_ids":["https://openalex.org/I4210143795"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5088965681"],"corresponding_institution_ids":["https://openalex.org/I4210143795"],"apc_list":null,"apc_paid":null,"fwci":3.1642,"has_fulltext":false,"cited_by_count":111,"citation_normalized_percentile":{"value":0.92611117,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"55","issue":"11","first_page":"2475","last_page":"2484"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.8995000123977661,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.8995000123977661,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12327","display_name":"Various Chemistry Research Topics","score":0.8532999753952026,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10636","display_name":"Innovative Teaching and Learning Methods","score":0.7936000227928162,"subfield":{"id":"https://openalex.org/subfields/3204","display_name":"Developmental and Educational Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cheminformatics","display_name":"Cheminformatics","score":0.841171145439148},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6876384019851685},{"id":"https://openalex.org/keywords/usability","display_name":"Usability","score":0.678551435470581},{"id":"https://openalex.org/keywords/virtual-reality","display_name":"Virtual reality","score":0.6471259593963623},{"id":"https://openalex.org/keywords/virtual-screening","display_name":"Virtual screening","score":0.6169297099113464},{"id":"https://openalex.org/keywords/human\u2013computer-interaction","display_name":"Human\u2013computer interaction","score":0.5690405964851379},{"id":"https://openalex.org/keywords/focus","display_name":"Focus (optics)","score":0.4305300712585449},{"id":"https://openalex.org/keywords/gesture","display_name":"Gesture","score":0.41661351919174194},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.41291409730911255},{"id":"https://openalex.org/keywords/world-wide-web","display_name":"World Wide Web","score":0.3692837655544281},{"id":"https://openalex.org/keywords/computer-graphics","display_name":"Computer graphics (images)","score":0.3206122815608978},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.25636136531829834},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.20360156893730164}],"concepts":[{"id":"https://openalex.org/C68762167","wikidata":"https://www.wikidata.org/wiki/Q910164","display_name":"Cheminformatics","level":2,"score":0.841171145439148},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6876384019851685},{"id":"https://openalex.org/C170130773","wikidata":"https://www.wikidata.org/wiki/Q216378","display_name":"Usability","level":2,"score":0.678551435470581},{"id":"https://openalex.org/C194969405","wikidata":"https://www.wikidata.org/wiki/Q170519","display_name":"Virtual reality","level":2,"score":0.6471259593963623},{"id":"https://openalex.org/C103697762","wikidata":"https://www.wikidata.org/wiki/Q4112105","display_name":"Virtual screening","level":3,"score":0.6169297099113464},{"id":"https://openalex.org/C107457646","wikidata":"https://www.wikidata.org/wiki/Q207434","display_name":"Human\u2013computer interaction","level":1,"score":0.5690405964851379},{"id":"https://openalex.org/C192209626","wikidata":"https://www.wikidata.org/wiki/Q190909","display_name":"Focus (optics)","level":2,"score":0.4305300712585449},{"id":"https://openalex.org/C207347870","wikidata":"https://www.wikidata.org/wiki/Q371174","display_name":"Gesture","level":2,"score":0.41661351919174194},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.41291409730911255},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.3692837655544281},{"id":"https://openalex.org/C121684516","wikidata":"https://www.wikidata.org/wiki/Q7600677","display_name":"Computer graphics (images)","level":1,"score":0.3206122815608978},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.25636136531829834},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.20360156893730164},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C147597530","wikidata":"https://www.wikidata.org/wiki/Q369472","display_name":"Computational chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005868","descriptor_name":"Gestures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005868","descriptor_name":"Gestures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005868","descriptor_name":"Gestures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014584","descriptor_name":"User-Computer Interface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015195","descriptor_name":"Drug Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017076","descriptor_name":"Computer-Aided Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017076","descriptor_name":"Computer-Aided Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017076","descriptor_name":"Computer-Aided Design","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021621","descriptor_name":"Imaging, Three-Dimensional","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1021/acs.jcim.5b00544","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.5b00544","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:26558887","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26558887","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null},{"id":"pmh:oai:lup.lub.lu.se:eb899e8f-b0e7-4739-9026-f033d77a4bbb","is_oa":false,"landing_page_url":"https://lup.lub.lu.se/record/8539728","pdf_url":null,"source":{"id":"https://openalex.org/S4306400536","display_name":"Lund University Publications (Lund University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I187531555","host_organization_name":"Lund University","host_organization_lineage":["https://openalex.org/I187531555"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ISSN: 1549-960X","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1516459493","https://openalex.org/W1572961809","https://openalex.org/W1975447903","https://openalex.org/W1985854865","https://openalex.org/W2016277862","https://openalex.org/W2026258231","https://openalex.org/W2029667189","https://openalex.org/W2030841140","https://openalex.org/W2058284855","https://openalex.org/W2064965882","https://openalex.org/W2113808486","https://openalex.org/W2122399640","https://openalex.org/W2126466006","https://openalex.org/W2130479394","https://openalex.org/W2132629607","https://openalex.org/W2161040595","https://openalex.org/W2169678694","https://openalex.org/W2502955410","https://openalex.org/W4242662831"],"related_works":["https://openalex.org/W4362464865","https://openalex.org/W2098840560","https://openalex.org/W4302604134","https://openalex.org/W2768880727","https://openalex.org/W2059230675","https://openalex.org/W1964657534","https://openalex.org/W2376003823","https://openalex.org/W2621548818","https://openalex.org/W2113146994","https://openalex.org/W2073081213"],"abstract_inverted_index":{"Recent":[0],"advances":[1],"in":[2,26,136],"interaction":[3],"design":[4],"have":[5,53],"created":[6],"new":[7],"ways":[8],"to":[9,17,35,44,76,107,110],"use":[10],"computers.":[11],"One":[12],"example":[13],"is":[14,33,74,83,142],"the":[15,27,78,88,95],"ability":[16],"create":[18,77],"enhanced":[19],"3D":[20],"environments":[21],"that":[22],"simulate":[23],"physical":[24],"presence":[25],"real":[28],"world--a":[29],"virtual":[30,62,79,132],"reality.":[31],"This":[32],"relevant":[34],"drug":[36],"discovery":[37],"since":[38],"molecular":[39],"models":[40],"are":[41],"frequently":[42],"used":[43,75],"obtain":[45],"deeper":[46],"understandings":[47],"of,":[48],"say,":[49],"ligand-protein":[50],"complexes.":[51],"We":[52,127],"developed":[54,117],"a":[55,61,71,119],"tool":[56],"(Molecular":[57],"Rift),":[58],"which":[59],"creates":[60],"reality":[63],"environment":[64],"steered":[65],"with":[66,118,129],"hand":[67],"movements.":[68],"Oculus":[69],"Rift,":[70],"head-mounted":[72],"display,":[73],"settings.":[80],"The":[81,101],"program":[82],"controlled":[84],"by":[85],"gesture-recognition,":[86],"using":[87],"gaming":[89],"sensor":[90],"MS":[91],"Kinect":[92],"v2,":[93],"eliminating":[94],"need":[96],"for":[97],"standard":[98],"input":[99],"devices.":[100],"Open":[102],"Babel":[103],"toolkit":[104],"was":[105,116],"integrated":[106],"provide":[108],"access":[109],"powerful":[111],"cheminformatics":[112],"functions.":[113],"Molecular":[114,140],"Rift":[115,141],"focus":[120],"on":[121,131],"usability,":[122],"including":[123],"iterative":[124],"test-group":[125],"evaluations.":[126],"conclude":[128],"reflections":[130],"reality's":[133],"future":[134],"capabilities":[135],"chemistry":[137],"and":[138,145],"education.":[139],"open":[143],"source":[144],"can":[146],"be":[147],"downloaded":[148],"from":[149],"GitHub.":[150]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":16},{"year":2020,"cited_by_count":17},{"year":2019,"cited_by_count":17},{"year":2018,"cited_by_count":13},{"year":2017,"cited_by_count":5},{"year":2016,"cited_by_count":5}],"updated_date":"2026-08-12T21:12:35.861297","created_date":"2025-10-10T00:00:00"}