{"id":"https://openalex.org/W26606666","doi":"https://doi.org/10.1021/acs.jcim.5b00501","title":"\u4e2d\u8033\u75be\u60a3\u306b\u304a\u3051\u308b\u5185\u8996\u93e1(\u91dd\u72b6\u93e1)\u306e\u4f7f\u7528","display_name":"\u4e2d\u8033\u75be\u60a3\u306b\u304a\u3051\u308b\u5185\u8996\u93e1(\u91dd\u72b6\u93e1)\u306e\u4f7f\u7528","publication_year":1996,"publication_date":"1996-09-05","ids":{"openalex":"https://openalex.org/W26606666","doi":"https://doi.org/10.1021/acs.jcim.5b00501","mag":"26606666"},"language":"en","primary_location":{"id":"mag:26606666","is_oa":false,"landing_page_url":"https://ci.nii.ac.jp/naid/10024561298","pdf_url":null,"source":{"id":"https://openalex.org/S2764932054","display_name":"Otology Japan","issn_l":"0917-2025","issn":["0917-2025"],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/P4353108578","host_organization_name":"Japan Otological Society","host_organization_lineage":["https://openalex.org/P4353108578"],"host_organization_lineage_names":["Japan Otological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Otology Japan","raw_type":null},"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"\u771f\u4e00 \u5b87\u4f50\u7f8e","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u771f\u4e00 \u5b87\u4f50\u7f8e","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081663219","display_name":"\u7e41\u4fca \u85e4\u7530","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u7e41\u4fca \u85e4\u7530","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059263491","display_name":"\u654f\u5149 \u6a4b\u672c","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u654f\u5149 \u6a4b\u672c","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020024586","display_name":"\u732a\u80a1\u4eac \u5de5\u7a70","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u732a\u80a1\u4eac \u5de5\u7a70","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5041690445","display_name":"\u79c0\u4e00 \u65b0\u5ddd","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"\u79c0\u4e00 \u65b0\u5ddd","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00176378,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"4","first_page":"231","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.9840999841690063,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior","score":0.9840999841690063,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11048","display_name":"Bacteriophages and microbial interactions","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11177","display_name":"Spectroscopy and Quantum Chemical Studies","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4964960217475891},{"id":"https://openalex.org/keywords/audiology","display_name":"Audiology","score":0.3212462067604065}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4964960217475891},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.3212462067604065}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:26606666","is_oa":false,"landing_page_url":"https://ci.nii.ac.jp/naid/10024561298","pdf_url":null,"source":{"id":"https://openalex.org/S2764932054","display_name":"Otology Japan","issn_l":"0917-2025","issn":["0917-2025"],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/P4353108578","host_organization_name":"Japan Otological Society","host_organization_lineage":["https://openalex.org/P4353108578"],"host_organization_lineage_names":["Japan Otological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Otology Japan","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":[],"abstract_inverted_index":{"The":[0,122],"physical":[1],"and":[2,23,28,56,77,109,199,252],"chemical":[3],"characterization":[4],"of":[5,9,17,44,80,88,96,111,124,136,149,158,160,249,266],"biological":[6,51,247,267],"membranes":[7,45,135,159,248],"is":[8,53,64],"fundamental":[10],"importance":[11],"for":[12,75,117,140],"understanding":[13],"the":[14,42,50,94,150,258,263],"functional":[15],"role":[16],"lipid":[18,138,152,231],"bilayers":[19,102],"in":[20,62,166],"shaping":[21],"cells":[22],"organelles,":[24],"steering":[25],"vesicle":[26],"trafficking":[27],"promoting":[29],"membrane-protein":[30],"signaling.":[31],"Molecular":[32],"dynamics":[33],"simulations":[34],"stand":[35],"as":[36,115,163,241,253],"a":[37,66,73,229,242,254],"powerful":[38],"tool":[39,244],"to":[40,126,245,257,261],"probe":[41],"properties":[43,265],"at":[46],"atomistic":[47],"level.":[48],"However,":[49],"membrane":[52,113,129,224,268],"highly":[54],"complex,":[55],"closely":[57],"mimicking":[58],"its":[59],"physiological":[60],"constitution":[61],"silico":[63],"not":[65],"straightforward":[67],"task.":[68],"Here,":[69],"we":[70,155],"present":[71],"LipidBuilder,":[72],"framework":[74],"creating":[76],"storing":[78],"models":[79,130,157,225],"biologically":[81],"relevant":[82],"phospholipid":[83],"species":[84],"with":[85],"acyl":[86],"tails":[87],"heterogeneous":[89,161],"composition.":[90],"LipidBuilder":[91,125,240],"also":[92],"enables":[93],"assembly":[95],"these":[97],"database-stored":[98],"lipids":[99],"into":[100],"realistic":[101,223],"featuring":[103],"asymmetric":[104],"distribution":[105],"on":[106],"layer":[107],"leaflets":[108],"concentration":[110],"given":[112],"constituents":[114],"defined,":[116],"example,":[118],"by":[119,133],"lipidomics":[120],"experiments.":[121,237],"ability":[123],"assemble":[127],"robust":[128,255],"was":[131],"validated":[132],"simulating":[134],"homogeneous":[137],"composition":[139,232],"which":[141],"experimental":[142],"data":[143],"are":[144],"available.":[145],"Furthermore,":[146],"taking":[147],"advantage":[148],"extensive":[151],"headgroup":[153],"repertoire,":[154],"assembled":[156],"nature":[162],"naturally":[164],"found":[165],"viral":[167],"(phage":[168],"PRD1),":[169],"bacterial":[170],"(Salmonella":[171],"enterica,":[172],"Laurinavicius":[173],",":[174,178,182,186,192,194,204,208,214,216],"S.":[175],";":[176,180,184,189,206,210],"Kakela":[177],"R.":[179],"Somerharju":[181],"P.":[183],"Bamford":[185],"D.":[187],"H.":[188],"Virology":[190],"2004":[191],"322":[193],"328":[195],"-":[196,218],"336":[197],")":[198,220],"plant":[200],"(Chlorella":[201],"kessleri,":[202],"Rezanka":[203],"T.":[205],"Podojil":[207],"M.":[209],"J.":[211],"Chromatogr.":[212],"1989":[213],"463":[215],"397":[217],"408":[219],"organisms.":[221],"These":[222],"were":[226],"built":[227],"using":[228,269],"near-exact":[230],"revealed":[233],"from":[234],"analytical":[235],"chemistry":[236],"We":[238],"suggest":[239],"useful":[243],"model":[246],"near-biological":[250],"complexity,":[251],"complement":[256],"current":[259],"efforts":[260],"characterize":[262],"biophysical":[264],"molecular":[270],"simulation.":[271]},"counts_by_year":[],"updated_date":"2025-07-23T07:15:27.626105","created_date":"2016-06-24T00:00:00"}