{"id":"https://openalex.org/W4409254995","doi":"https://doi.org/10.1021/acs.jcim.4c02366","title":"Nonequilibrium Self-Assembly Control by the Stochastic Landscape Method","display_name":"Nonequilibrium Self-Assembly Control by the Stochastic Landscape Method","publication_year":2025,"publication_date":"2025-04-08","ids":{"openalex":"https://openalex.org/W4409254995","doi":"https://doi.org/10.1021/acs.jcim.4c02366","pmid":"https://pubmed.ncbi.nlm.nih.gov/40198896"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.4c02366","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.4c02366","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1021/acs.jcim.4c02366","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009307754","display_name":"Michael Faran","orcid":"https://orcid.org/0009-0001-7545-1477"},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Michael Faran","raw_affiliation_strings":["Department of Biomedical Engineering, Faculty of Engineering","Tel Aviv University"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Faculty of Engineering","institution_ids":[]},{"raw_affiliation_string":"Tel Aviv University","institution_ids":["https://openalex.org/I16391192"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5054412919","display_name":"Gili Bisker","orcid":"https://orcid.org/0000-0003-2592-7956"},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]},{"id":"https://openalex.org/I2801304276","display_name":"Center for NanoScience","ror":"https://ror.org/002epp671","country_code":"DE","type":"facility","lineage":["https://openalex.org/I2801304276","https://openalex.org/I8204097"]},{"id":"https://openalex.org/I4210162773","display_name":"Living Systems (United States)","ror":"https://ror.org/05sft7551","country_code":"US","type":"company","lineage":["https://openalex.org/I4210162773"]}],"countries":["DE","IL","US"],"is_corresponding":true,"raw_author_name":"Gili Bisker","raw_affiliation_strings":["Department of Biomedical Engineering, Faculty of Engineering","Tel Aviv University","The Center for Nanoscience and Nanotechnology","The Center for Physics and Chemistry of Living Systems"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Faculty of Engineering","institution_ids":[]},{"raw_affiliation_string":"Tel Aviv University","institution_ids":["https://openalex.org/I16391192"]},{"raw_affiliation_string":"The Center for Nanoscience and Nanotechnology","institution_ids":["https://openalex.org/I2801304276"]},{"raw_affiliation_string":"The Center for Physics and Chemistry of Living Systems","institution_ids":["https://openalex.org/I4210162773"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5054412919"],"corresponding_institution_ids":["https://openalex.org/I16391192","https://openalex.org/I2801304276","https://openalex.org/I4210162773"],"apc_list":null,"apc_paid":null,"fwci":3.321,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.91509036,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":98},"biblio":{"volume":"65","issue":"8","first_page":"4067","last_page":"4080"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12784","display_name":"Modular Robots and Swarm Intelligence","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12784","display_name":"Modular Robots and Swarm Intelligence","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/2210","display_name":"Mechanical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13187","display_name":"Diffusion and Search Dynamics","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11486","display_name":"Micro and Nano Robotics","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/3104","display_name":"Condensed Matter Physics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-equilibrium-thermodynamics","display_name":"Non-equilibrium thermodynamics","score":0.6385562419891357},{"id":"https://openalex.org/keywords/statistical-physics","display_name":"Statistical physics","score":0.4960378110408783},{"id":"https://openalex.org/keywords/control","display_name":"Control (management)","score":0.44481465220451355},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.39385461807250977},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.3588240146636963},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.2602381706237793},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.1716422438621521},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.16854935884475708},{"id":"https://openalex.org/keywords/thermodynamics","display_name":"Thermodynamics","score":0.14971181750297546}],"concepts":[{"id":"https://openalex.org/C74859849","wikidata":"https://www.wikidata.org/wiki/Q2466686","display_name":"Non-equilibrium thermodynamics","level":2,"score":0.6385562419891357},{"id":"https://openalex.org/C121864883","wikidata":"https://www.wikidata.org/wiki/Q677916","display_name":"Statistical physics","level":1,"score":0.4960378110408783},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.44481465220451355},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.39385461807250977},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.3588240146636963},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.2602381706237793},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1716422438621521},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.16854935884475708},{"id":"https://openalex.org/C97355855","wikidata":"https://www.wikidata.org/wiki/Q11473","display_name":"Thermodynamics","level":1,"score":0.14971181750297546}],"mesh":[{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007700","descriptor_name":"Kinetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013269","descriptor_name":"Stochastic Processes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013816","descriptor_name":"Thermodynamics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1021/acs.jcim.4c02366","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.4c02366","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:40198896","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/40198896","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:12042269","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12042269","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Chem Inf Model","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1021/acs.jcim.4c02366","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.4c02366","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.49000000953674316,"display_name":"Climate action","id":"https://metadata.un.org/sdg/13"}],"awards":[{"id":"https://openalex.org/G1247594781","display_name":null,"funder_award_id":"101039127","funder_id":"https://openalex.org/F4320334678","funder_display_name":"European Research Council"},{"id":"https://openalex.org/G3096442006","display_name":null,"funder_award_id":"W911NF-21-1-0101","funder_id":"https://openalex.org/F4320338281","funder_display_name":"Army Research Office"},{"id":"https://openalex.org/G554964189","display_name":null,"funder_award_id":"FA9550-20-1-0426","funder_id":"https://openalex.org/F4320338279","funder_display_name":"Air Force Office of Scientific Research"}],"funders":[{"id":"https://openalex.org/F4320322596","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49"},{"id":"https://openalex.org/F4320334678","display_name":"European Research Council","ror":"https://ror.org/0472cxd90"},{"id":"https://openalex.org/F4320338279","display_name":"Air Force Office of Scientific Research","ror":"https://ror.org/011e9bt93"},{"id":"https://openalex.org/F4320338281","display_name":"Army Research Office","ror":"https://ror.org/05epdh915"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":121,"referenced_works":["https://openalex.org/W954788914","https://openalex.org/W1666636243","https://openalex.org/W1964353449","https://openalex.org/W1965001296","https://openalex.org/W1973096291","https://openalex.org/W1985371657","https://openalex.org/W1987482901","https://openalex.org/W1991279472","https://openalex.org/W1998381903","https://openalex.org/W2007740207","https://openalex.org/W2009739930","https://openalex.org/W2024060531","https://openalex.org/W2027591755","https://openalex.org/W2030886354","https://openalex.org/W2040809566","https://openalex.org/W2042321087","https://openalex.org/W2048938594","https://openalex.org/W2060953134","https://openalex.org/W2069092525","https://openalex.org/W2074616759","https://openalex.org/W2083579241","https://openalex.org/W2084168394","https://openalex.org/W2092144432","https://openalex.org/W2093456062","https://openalex.org/W2095170141","https://openalex.org/W2095921114","https://openalex.org/W2105251006","https://openalex.org/W2118653281","https://openalex.org/W2121563903","https://openalex.org/W2127081697","https://openalex.org/W2139411356","https://openalex.org/W2149984051","https://openalex.org/W2156375046","https://openalex.org/W2162452471","https://openalex.org/W2519267297","https://openalex.org/W2594090905","https://openalex.org/W2598696960","https://openalex.org/W2739312068","https://openalex.org/W2806618391","https://openalex.org/W2898017366","https://openalex.org/W2965689387","https://openalex.org/W3006399194","https://openalex.org/W3007345724","https://openalex.org/W3010993165","https://openalex.org/W3014996331","https://openalex.org/W3017213551","https://openalex.org/W3017827393","https://openalex.org/W3021243098","https://openalex.org/W3024860826","https://openalex.org/W3101307536","https://openalex.org/W3101861338","https://openalex.org/W3107430188","https://openalex.org/W3114425778","https://openalex.org/W3131929255","https://openalex.org/W3134796673","https://openalex.org/W3135486192","https://openalex.org/W3155662795","https://openalex.org/W3207296509","https://openalex.org/W4200081036","https://openalex.org/W4200105953","https://openalex.org/W4200208102","https://openalex.org/W4200633438","https://openalex.org/W4205457840","https://openalex.org/W4206057716","https://openalex.org/W4206944861","https://openalex.org/W4214893343","https://openalex.org/W4220670930","https://openalex.org/W4225426745","https://openalex.org/W4226257619","https://openalex.org/W4283079372","https://openalex.org/W4296240589","https://openalex.org/W4305071863","https://openalex.org/W4306247960","https://openalex.org/W4311086337","https://openalex.org/W4311284745","https://openalex.org/W4312077276","https://openalex.org/W4313294036","https://openalex.org/W4313528453","https://openalex.org/W4315476272","https://openalex.org/W4317213371","https://openalex.org/W4318323589","https://openalex.org/W4321764526","https://openalex.org/W4323024810","https://openalex.org/W4323037693","https://openalex.org/W4323310463","https://openalex.org/W4361302539","https://openalex.org/W4365444228","https://openalex.org/W4375811867","https://openalex.org/W4378071595","https://openalex.org/W4382936365","https://openalex.org/W4383186842","https://openalex.org/W4384519408","https://openalex.org/W4385841635","https://openalex.org/W4386201376","https://openalex.org/W4386316361","https://openalex.org/W4388729179","https://openalex.org/W4388814000","https://openalex.org/W4388851181","https://openalex.org/W4389300168","https://openalex.org/W4389459215","https://openalex.org/W4390940873","https://openalex.org/W4393899201","https://openalex.org/W4393941651","https://openalex.org/W4394973335","https://openalex.org/W4398143222","https://openalex.org/W4399169414","https://openalex.org/W4399295242","https://openalex.org/W4399550303","https://openalex.org/W4399818284","https://openalex.org/W4399985538","https://openalex.org/W4400035244","https://openalex.org/W4400444125","https://openalex.org/W4400583283","https://openalex.org/W4400779025","https://openalex.org/W4401413739","https://openalex.org/W4401820240","https://openalex.org/W4402399502","https://openalex.org/W4403114776","https://openalex.org/W4403539677","https://openalex.org/W4405995773","https://openalex.org/W4406930352"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W1987477346","https://openalex.org/W2207589738","https://openalex.org/W2963608419","https://openalex.org/W2002507860","https://openalex.org/W2212137565","https://openalex.org/W2032833281","https://openalex.org/W2137556991","https://openalex.org/W3122576246","https://openalex.org/W2068452861"],"abstract_inverted_index":{"Self-assembly":[0],"of":[1,20,31,42,78,171],"building":[2],"blocks":[3],"is":[4],"a":[5,60,97,146],"fundamental":[6],"process":[7],"in":[8,45,69,88,175],"nanotechnology,":[9],"materials":[10,164],"science,":[11],"and":[12,22,40,55,114,136,162,177],"biological":[13,176],"systems,":[14],"offering":[15],"pathways":[16],"to":[17,84,103,117],"the":[18,29,38,75,93,111,124],"formation":[19],"complex":[21],"functional":[23],"structures":[24],"through":[25],"local":[26],"interactions.":[27],"However,":[28],"lack":[30],"effective":[32],"error":[33],"correction":[34],"mechanisms":[35],"often":[36],"limits":[37],"efficiency":[39],"precision":[41,160],"assembly,":[43],"particularly":[44],"systems":[46],"with":[47,156],"strong":[48],"binding":[49],"energies.":[50],"Inspired":[51],"by":[52],"cellular":[53],"processes":[54],"stochastic":[56,94],"resetting,":[57],"we":[58],"present":[59],"closed-loop":[61],"feedback":[62],"control":[63,119],"method":[64],"that":[65,123],"employs":[66],"transient":[67,125],"modulations":[68],"interaction":[70],"energies,":[71],"mimicking,":[72],"for":[73,151,159],"instance,":[74],"global":[76],"effect":[77],"pH":[79],"changes":[80],"as":[81],"nonequilibrium":[82,153],"drives":[83],"optimize":[85],"assembly":[86,134,138,154,174],"outcomes":[87],"real":[89],"time.":[90],"By":[91],"leveraging":[92],"landscape":[95],"method,":[96],"framework":[98,150],"using":[99],"energy":[100,115,126],"trend-based":[101],"segmentation":[102],"predict":[104],"self-assembly":[105],"behavior,":[106],"our":[107,169],"approach":[108],"dynamically":[109],"analyzes":[110],"system's":[112],"state":[113],"trends":[116],"guide":[118],"actions.":[120],"We":[121],"show":[122],"modulation":[127],"during":[128],"kinetic":[129],"trapping":[130],"conditions":[131],"substantially":[132],"enhances":[133],"yields":[135],"reduces":[137],"times":[139],"across":[140],"diverse":[141],"scenarios.":[142],"This":[143],"strategy":[144],"provides":[145],"broadly":[147],"applicable,":[148],"data-driven":[149],"optimizing":[152],"processes,":[155],"potential":[157],"implications":[158],"manufacturing":[161],"responsive":[163],"design,":[165],"while":[166],"also":[167],"advancing":[168],"understanding":[170],"controlled":[172],"molecular":[173],"synthetic":[178],"contexts.":[179]},"counts_by_year":[{"year":2025,"cited_by_count":5}],"updated_date":"2026-04-14T08:04:32.555800","created_date":"2025-10-10T00:00:00"}
