{"id":"https://openalex.org/W4402613109","doi":"https://doi.org/10.1021/acs.jcim.4c01296","title":"MHIPM: Accurate Prediction of Microbe-Host Interactions Using Multiview Features from a Heterogeneous Microbial Network","display_name":"MHIPM: Accurate Prediction of Microbe-Host Interactions Using Multiview Features from a Heterogeneous Microbial Network","publication_year":2024,"publication_date":"2024-09-18","ids":{"openalex":"https://openalex.org/W4402613109","doi":"https://doi.org/10.1021/acs.jcim.4c01296","pmid":"https://pubmed.ncbi.nlm.nih.gov/39289839"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.4c01296","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.4c01296","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064538645","display_name":"Jie Pan","orcid":"https://orcid.org/0000-0002-4993-298X"},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I37802460","display_name":"Northwest University","ror":"https://ror.org/00z3td547","country_code":"CN","type":"education","lineage":["https://openalex.org/I37802460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Pan","raw_affiliation_strings":["Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China","institution_ids":["https://openalex.org/I1327237609","https://openalex.org/I37802460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100334997","display_name":"Guangming Zhang","orcid":"https://orcid.org/0009-0005-7552-2561"},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I37802460","display_name":"Northwest University","ror":"https://ror.org/00z3td547","country_code":"CN","type":"education","lineage":["https://openalex.org/I37802460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guangming Zhang","raw_affiliation_strings":["Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China","institution_ids":["https://openalex.org/I1327237609","https://openalex.org/I37802460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101710557","display_name":"Yong Yang","orcid":"https://orcid.org/0000-0002-6775-1189"},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I37802460","display_name":"Northwest University","ror":"https://ror.org/00z3td547","country_code":"CN","type":"education","lineage":["https://openalex.org/I37802460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yong Yang","raw_affiliation_strings":["Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China","institution_ids":["https://openalex.org/I1327237609","https://openalex.org/I37802460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023755979","display_name":"Wenli Yang","orcid":"https://orcid.org/0000-0002-4885-2531"},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I37802460","display_name":"Northwest University","ror":"https://ror.org/00z3td547","country_code":"CN","type":"education","lineage":["https://openalex.org/I37802460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenli Yang","raw_affiliation_strings":["Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China","institution_ids":["https://openalex.org/I1327237609","https://openalex.org/I37802460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084621992","display_name":"Ning Mao","orcid":null},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I37802460","display_name":"Northwest University","ror":"https://ror.org/00z3td547","country_code":"CN","type":"education","lineage":["https://openalex.org/I37802460"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ning Mao","raw_affiliation_strings":["Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China","institution_ids":["https://openalex.org/I1327237609","https://openalex.org/I37802460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019805735","display_name":"Zhu\u2010Hong You","orcid":"https://orcid.org/0000-0003-1266-2696"},"institutions":[{"id":"https://openalex.org/I17145004","display_name":"Northwestern Polytechnical University","ror":"https://ror.org/01y0j0j86","country_code":"CN","type":"education","lineage":["https://openalex.org/I17145004"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhuhong You","raw_affiliation_strings":["School of Computer Science, Northwestern Polytechnical University, Xi\u2019an 710129, China"],"affiliations":[{"raw_affiliation_string":"School of Computer Science, Northwestern Polytechnical University, Xi\u2019an 710129, China","institution_ids":["https://openalex.org/I17145004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082768846","display_name":"Jie Feng","orcid":"https://orcid.org/0000-0001-5172-6643"},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210124148","display_name":"Microbiology Institute of Shaanxi","ror":"https://ror.org/02wt4jg41","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210124148"]},{"id":"https://openalex.org/I4210134982","display_name":"Institute of Microbiology","ror":"https://ror.org/047yhep71","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210134982"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Feng","raw_affiliation_strings":["State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China"],"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China","institution_ids":["https://openalex.org/I4210124148","https://openalex.org/I4210134982","https://openalex.org/I19820366"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100340278","display_name":"Shiwei Wang","orcid":"https://orcid.org/0000-0001-8890-9080"},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I37802460","display_name":"Northwest University","ror":"https://ror.org/00z3td547","country_code":"CN","type":"education","lineage":["https://openalex.org/I37802460"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shiwei Wang","raw_affiliation_strings":["Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China","institution_ids":["https://openalex.org/I1327237609","https://openalex.org/I37802460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100834640","display_name":"Yanmei Sun","orcid":null},"institutions":[{"id":"https://openalex.org/I1327237609","display_name":"Ministry of Education of the People's Republic of China","ror":"https://ror.org/01mv9t934","country_code":"CN","type":"government","lineage":["https://openalex.org/I1327237609","https://openalex.org/I4210127390"]},{"id":"https://openalex.org/I37802460","display_name":"Northwest University","ror":"https://ror.org/00z3td547","country_code":"CN","type":"education","lineage":["https://openalex.org/I37802460"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yanmei Sun","raw_affiliation_strings":["Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China"],"affiliations":[{"raw_affiliation_string":"Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, Provincial Key Laboratory of Biotechnology of Shaanxi Province, the College of Life Sciences, Northwest University, Xi\u2019an 710069, China","institution_ids":["https://openalex.org/I1327237609","https://openalex.org/I37802460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5100340278","https://openalex.org/A5100834640"],"corresponding_institution_ids":["https://openalex.org/I1327237609","https://openalex.org/I37802460"],"apc_list":null,"apc_paid":null,"fwci":0.7018,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.70348015,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"64","issue":"19","first_page":"7793","last_page":"7805"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12254","display_name":"Machine Learning in Bioinformatics","score":0.9972000122070312,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9954000115394592,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/host","display_name":"Host (biology)","score":0.7336440086364746},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5764597654342651},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4495689272880554},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.32316774129867554},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1604647934436798},{"id":"https://openalex.org/keywords/ecology","display_name":"Ecology","score":0.10711181163787842}],"concepts":[{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.7336440086364746},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5764597654342651},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4495689272880554},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32316774129867554},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1604647934436798},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.10711181163787842}],"mesh":[{"descriptor_ui":"D000076662","descriptor_name":"Host Microbial Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076662","descriptor_name":"Host Microbial Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000076662","descriptor_name":"Host Microbial Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054884","descriptor_name":"Host-Pathogen Interactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/acs.jcim.4c01296","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acs.jcim.4c01296","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:39289839","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39289839","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G3639475604","display_name":null,"funder_award_id":"62325308","funder_id":"https://openalex.org/F4320336125","funder_display_name":"National Science Fund for Distinguished Young Scholars"},{"id":"https://openalex.org/G8247529839","display_name":null,"funder_award_id":"31770152","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8653513516","display_name":null,"funder_award_id":"2022FY101100","funder_id":"https://openalex.org/F4320321540","funder_display_name":"Ministry of Science and Technology of the People's Republic of China"},{"id":"https://openalex.org/G8748380971","display_name":null,"funder_award_id":"32170114","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G982217546","display_name":null,"funder_award_id":"23JRRM738","funder_id":"https://openalex.org/F4320322880","funder_display_name":"Natural Science Foundation of Gansu Province"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321540","display_name":"Ministry of Science and Technology of the People's Republic of China","ror":"https://ror.org/027s68j25"},{"id":"https://openalex.org/F4320322880","display_name":"Natural Science Foundation of Gansu Province","ror":null},{"id":"https://openalex.org/F4320336125","display_name":"National Science Fund for Distinguished Young Scholars","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1678356000","https://openalex.org/W1888005072","https://openalex.org/W1994421736","https://openalex.org/W2041000367","https://openalex.org/W2066151306","https://openalex.org/W2097308346","https://openalex.org/W2119310431","https://openalex.org/W2154851992","https://openalex.org/W2165253681","https://openalex.org/W2167084464","https://openalex.org/W2168637722","https://openalex.org/W2290373888","https://openalex.org/W2393319904","https://openalex.org/W2465613542","https://openalex.org/W2469986620","https://openalex.org/W2472351724","https://openalex.org/W2526946522","https://openalex.org/W2597800471","https://openalex.org/W2795735740","https://openalex.org/W2804078698","https://openalex.org/W2894128290","https://openalex.org/W2911964244","https://openalex.org/W2912290085","https://openalex.org/W2949547296","https://openalex.org/W2954435903","https://openalex.org/W2987653794","https://openalex.org/W2990200213","https://openalex.org/W2999005973","https://openalex.org/W3005685721","https://openalex.org/W3097005383","https://openalex.org/W3104097132","https://openalex.org/W3108760621","https://openalex.org/W3122809531","https://openalex.org/W3127064341","https://openalex.org/W3136154691","https://openalex.org/W3137258609","https://openalex.org/W3202488381","https://openalex.org/W3217319747","https://openalex.org/W4282045748","https://openalex.org/W4294558607","https://openalex.org/W4321483984","https://openalex.org/W4327550249","https://openalex.org/W4387090137","https://openalex.org/W4388979610","https://openalex.org/W4392263494","https://openalex.org/W4396721167","https://openalex.org/W4399893452","https://openalex.org/W4401332220"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052","https://openalex.org/W2382290278","https://openalex.org/W4395014643"],"abstract_inverted_index":{"Current":[0],"studies":[1,184],"have":[2],"demonstrated":[3],"that":[4,100,165],"microbe-host":[5],"interactions":[6,18],"(MHIs)":[7],"play":[8],"important":[9],"roles":[10],"in":[11,209],"human":[12,103,191],"public":[13],"health.":[14],"Therefore,":[15],"identifying":[16],"the":[17,27,30,116,135,151,155,166,195],"between":[19],"microbes":[20,216],"and":[21,32,54,108,122,177,185,206,212],"hosts":[22,63],"is":[23,58,203,221],"beneficial":[24],"to":[25,60,84,133,149],"understanding":[26],"role":[28],"of":[29,46,102,115,197],"microbiome":[31],"their":[33],"underlying":[34],"mechanisms.":[35],"However,":[36],"traditional":[37],"wet-lab":[38],"experimental":[39,70],"approaches":[40,66],"are":[41,51],"insufficient":[42],"for":[43,67,189,217],"large-scale":[44],"exploration":[45],"candidate":[47,215],"microbes,":[48],"as":[49],"they":[50],"costly,":[52],"laborious,":[53],"time-consuming.":[55],"Thus,":[56],"it":[57],"critical":[59],"prioritize":[61],"microbe-interacting":[62],"by":[64,87],"computational":[65],"further":[68,193],"biological":[69,90,218],"validation.":[71],"In":[72,181,200],"this":[73],"work,":[74],"we":[75,93,112],"proposed":[76],"a":[77,96,123,130],"novel":[78],"deep":[79],"learning-based":[80,144],"method":[81,208],"called":[82],"MHIPM,":[83],"predict":[85],"MHIs":[86,211],"utilizing":[88],"multisource":[89],"information.":[91],"Specifically,":[92],"first":[94],"constructed":[95],"heterogeneous":[97,156],"microbial":[98],"network":[99],"consisted":[101],"proteins,":[104],"viruses,":[105],"bacteriophages":[106],"(phages),":[107],"pathogenic":[109],"bacteria.":[110],"Next,":[111],"used":[113,148],"one":[114],"largest":[117],"protein":[118,139],"language":[119],"models,":[120],"ESM-2,":[121],"document":[124],"embedding":[125],"model,":[126,145],"doc2vec,":[127],"combined":[128],"with":[129],"self-attention":[131],"mechanism":[132],"extract":[134],"interview":[136],"features":[137,153],"from":[138,154],"sequences.":[140],"Then,":[141],"an":[142,204],"inductive":[143],"GraphSAGE,":[146],"was":[147],"capture":[150],"intraview":[152],"network.":[157],"Experimental":[158],"results":[159],"on":[160],"three":[161],"prediction":[162],"tasks":[163],"indicated":[164],"MHIPM":[167,202,220],"model":[168],"consistently":[169],"achieved":[170],"better":[171],"performance":[172],"than":[173],"seven":[174],"baseline":[175],"algorithms":[176],"its":[178],"four":[179],"variants.":[180],"addition,":[182],"case":[183],"molecular":[186],"docking":[187],"experiments":[188],"two":[190],"proteins":[192],"confirmed":[194],"effectiveness":[196],"our":[198],"model.":[199],"conclusion,":[201],"efficient":[205],"robust":[207],"predicting":[210],"provides":[213],"plausible":[214],"experiments.":[219],"available":[222],"at":[223],"https://github.com/JIENWU/MHIPM.":[224]},"counts_by_year":[{"year":2025,"cited_by_count":3}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}