{"id":"https://openalex.org/W4401282916","doi":"https://doi.org/10.1021/acs.jcim.4c00796","title":"Connectivity Network Feature Sharing in Single-Cell RNA Sequencing Data Identifies Rare Cells","display_name":"Connectivity Network Feature Sharing in Single-Cell RNA Sequencing Data Identifies Rare Cells","publication_year":2024,"publication_date":"2024-08-03","ids":{"openalex":"https://openalex.org/W4401282916","doi":"https://doi.org/10.1021/acs.jcim.4c00796","pmid":"https://pubmed.ncbi.nlm.nih.gov/39096508"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.4c00796","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1021/acs.jcim.4c00796","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076511286","display_name":"Shudong Wang","orcid":"https://orcid.org/0000-0001-6225-5525"},"institutions":[{"id":"https://openalex.org/I4210128818","display_name":"Institute of Software","ror":"https://ror.org/033dfsn42","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210128818"]},{"id":"https://openalex.org/I4210162190","display_name":"China University of Petroleum, East China","ror":"https://ror.org/05gbn2817","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210162190"]},{"id":"https://openalex.org/I44468530","display_name":"Qingdao University of Technology","ror":"https://ror.org/01qzc0f54","country_code":"CN","type":"education","lineage":["https://openalex.org/I44468530"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shudong Wang","raw_affiliation_strings":["Qingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266580, China","School of Information and Control Engineering, Qingdao University of Technology, Qingdao 266525, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266580, China","institution_ids":["https://openalex.org/I4210128818","https://openalex.org/I4210162190"]},{"raw_affiliation_string":"School of Information and Control Engineering, Qingdao University of Technology, Qingdao 266525, China","institution_ids":["https://openalex.org/I44468530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082780758","display_name":"Hengxiao Li","orcid":"https://orcid.org/0009-0002-9699-7169"},"institutions":[{"id":"https://openalex.org/I4210128818","display_name":"Institute of Software","ror":"https://ror.org/033dfsn42","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210128818"]},{"id":"https://openalex.org/I4210162190","display_name":"China University of Petroleum, East China","ror":"https://ror.org/05gbn2817","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210162190"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hengxiao Li","raw_affiliation_strings":["Qingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266580, China"],"raw_orcid":"https://orcid.org/0009-0002-9699-7169","affiliations":[{"raw_affiliation_string":"Qingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266580, China","institution_ids":["https://openalex.org/I4210128818","https://openalex.org/I4210162190"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100375491","display_name":"Yahui Liu","orcid":"https://orcid.org/0000-0002-0461-8348"},"institutions":[{"id":"https://openalex.org/I4210162190","display_name":"China University of Petroleum, East China","ror":"https://ror.org/05gbn2817","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210162190"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yahui Liu","raw_affiliation_strings":["College of Science, China University of Petroleum (East China), Qingdao 266580, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Science, China University of Petroleum (East China), Qingdao 266580, China","institution_ids":["https://openalex.org/I4210162190"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067844688","display_name":"Shanchen Pang","orcid":"https://orcid.org/0009-0007-5620-0609"},"institutions":[{"id":"https://openalex.org/I4210128818","display_name":"Institute of Software","ror":"https://ror.org/033dfsn42","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210128818"]},{"id":"https://openalex.org/I4210162190","display_name":"China University of Petroleum, East China","ror":"https://ror.org/05gbn2817","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210162190"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shanchen Pang","raw_affiliation_strings":["Qingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266580, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266580, China","institution_ids":["https://openalex.org/I4210128818","https://openalex.org/I4210162190"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062045805","display_name":"Sibo Qiao","orcid":"https://orcid.org/0000-0001-6922-5986"},"institutions":[{"id":"https://openalex.org/I198091727","display_name":"Tiangong University","ror":"https://ror.org/00xsr9m91","country_code":"CN","type":"education","lineage":["https://openalex.org/I198091727"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Sibo Qiao","raw_affiliation_strings":["The College of Software, Tiangong University, Tianjin 300387, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The College of Software, Tiangong University, Tianjin 300387, China","institution_ids":["https://openalex.org/I198091727"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085156744","display_name":"Jionglong Su","orcid":"https://orcid.org/0000-0001-5360-6493"},"institutions":[{"id":"https://openalex.org/I69356397","display_name":"Xi\u2019an Jiaotong-Liverpool University","ror":"https://ror.org/03zmrmn05","country_code":"CN","type":"education","lineage":["https://openalex.org/I69356397"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jionglong Su","raw_affiliation_strings":["School of AI and Advanced Computing, XJTLU Entrepreneur College (Taicang), Xi\u2019an Jiaotong-Liverpool University, Suzhou 215123, Jiangsu, China","School of AI and Advanced Computing, XJTLU Entrepreneur College (Taicang), Xi'an Jiaotong-Liverpool University, Suzhou 215123, Jiangsu, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of AI and Advanced Computing, XJTLU Entrepreneur College (Taicang), Xi\u2019an Jiaotong-Liverpool University, Suzhou 215123, Jiangsu, China","institution_ids":["https://openalex.org/I69356397"]},{"raw_affiliation_string":"School of AI and Advanced Computing, XJTLU Entrepreneur College (Taicang), Xi'an Jiaotong-Liverpool University, Suzhou 215123, Jiangsu, China","institution_ids":["https://openalex.org/I69356397"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025438179","display_name":"Shaoqiang Wang","orcid":"https://orcid.org/0000-0002-4111-6689"},"institutions":[{"id":"https://openalex.org/I4210128818","display_name":"Institute of Software","ror":"https://ror.org/033dfsn42","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210128818"]},{"id":"https://openalex.org/I4210162190","display_name":"China University of Petroleum, East China","ror":"https://ror.org/05gbn2817","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210162190"]},{"id":"https://openalex.org/I44468530","display_name":"Qingdao University of Technology","ror":"https://ror.org/01qzc0f54","country_code":"CN","type":"education","lineage":["https://openalex.org/I44468530"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shaoqiang Wang","raw_affiliation_strings":["Qingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266580, China","School of Information and Control Engineering, Qingdao University of Technology, Qingdao 266525, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Qingdao Institute of Software, College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266580, China","institution_ids":["https://openalex.org/I4210128818","https://openalex.org/I4210162190"]},{"raw_affiliation_string":"School of Information and Control Engineering, Qingdao University of Technology, Qingdao 266525, China","institution_ids":["https://openalex.org/I44468530"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004783206","display_name":"Yulin Zhang","orcid":"https://orcid.org/0000-0002-9125-5273"},"institutions":[{"id":"https://openalex.org/I80143920","display_name":"Shandong University of Science and Technology","ror":"https://ror.org/04gtjhw98","country_code":"CN","type":"education","lineage":["https://openalex.org/I80143920"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yulin Zhang","raw_affiliation_strings":["College of Mathematics and Systems Science, Shandong University of Science and Technology, Qingdao 266590, China"],"raw_orcid":"https://orcid.org/0000-0002-9125-5273","affiliations":[{"raw_affiliation_string":"College of Mathematics and Systems Science, Shandong University of Science and Technology, Qingdao 266590, China","institution_ids":["https://openalex.org/I80143920"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5004783206","https://openalex.org/A5067844688"],"corresponding_institution_ids":["https://openalex.org/I4210128818","https://openalex.org/I4210162190","https://openalex.org/I80143920"],"apc_list":null,"apc_paid":null,"fwci":0.1646,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.48649748,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"64","issue":"16","first_page":"6596","last_page":"6609"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.9749000072479248,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.9438999891281128,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6296454071998596},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.5642267465591431},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.49953317642211914},{"id":"https://openalex.org/keywords/cell","display_name":"Cell","score":0.4660784900188446},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4562065303325653},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4362727701663971},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4164281189441681},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.25351935625076294},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2020280659198761}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6296454071998596},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.5642267465591431},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.49953317642211914},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4660784900188446},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4562065303325653},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4362727701663971},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4164281189441681},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.25351935625076294},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2020280659198761},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D059010","descriptor_name":"Single-Cell Analysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1021/acs.jcim.4c00796","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1021/acs.jcim.4c00796","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:39096508","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39096508","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G4037382368","display_name":null,"funder_award_id":"ZR2020MH208","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G5881903318","display_name":null,"funder_award_id":"2021YFA1000103","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G6940641828","display_name":null,"funder_award_id":"ZR2021MH104","funder_id":"https://openalex.org/F4320324174","funder_display_name":"Natural Science Foundation of Shandong Province"},{"id":"https://openalex.org/G7895523656","display_name":null,"funder_award_id":"2021YFA1000102","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320324174","display_name":"Natural Science Foundation of Shandong Province","ror":null},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":63,"referenced_works":["https://openalex.org/W1563425389","https://openalex.org/W1974913955","https://openalex.org/W1982679982","https://openalex.org/W1999114171","https://openalex.org/W2010653277","https://openalex.org/W2015851881","https://openalex.org/W2035444281","https://openalex.org/W2043313845","https://openalex.org/W2056645762","https://openalex.org/W2057249739","https://openalex.org/W2060245619","https://openalex.org/W2079812792","https://openalex.org/W2088252378","https://openalex.org/W2104639807","https://openalex.org/W2110940238","https://openalex.org/W2131929474","https://openalex.org/W2139935404","https://openalex.org/W2150576367","https://openalex.org/W2154039449","https://openalex.org/W2161517578","https://openalex.org/W2330212410","https://openalex.org/W2465528287","https://openalex.org/W2737082469","https://openalex.org/W2767394894","https://openalex.org/W2793937297","https://openalex.org/W2794480084","https://openalex.org/W2800392236","https://openalex.org/W2804847416","https://openalex.org/W2805410771","https://openalex.org/W2886347923","https://openalex.org/W2897249806","https://openalex.org/W2900387735","https://openalex.org/W2902652978","https://openalex.org/W2907783748","https://openalex.org/W2921437380","https://openalex.org/W2951506174","https://openalex.org/W2956840440","https://openalex.org/W2999309192","https://openalex.org/W3009302866","https://openalex.org/W3038417586","https://openalex.org/W3103700416","https://openalex.org/W3106188259","https://openalex.org/W3118728054","https://openalex.org/W3134557264","https://openalex.org/W3150828794","https://openalex.org/W3156068899","https://openalex.org/W3180192281","https://openalex.org/W3213709307","https://openalex.org/W3216622453","https://openalex.org/W4210932541","https://openalex.org/W4221065117","https://openalex.org/W4225598893","https://openalex.org/W4289335819","https://openalex.org/W4312067472","https://openalex.org/W4313255490","https://openalex.org/W4362521490","https://openalex.org/W4376870967","https://openalex.org/W4376871315","https://openalex.org/W4386547575","https://openalex.org/W4387125037","https://openalex.org/W4390206253","https://openalex.org/W4390562578","https://openalex.org/W4390636271"],"related_works":["https://openalex.org/W2770593030","https://openalex.org/W3154990682","https://openalex.org/W2560201613","https://openalex.org/W2171975302","https://openalex.org/W2022352247","https://openalex.org/W4312219546","https://openalex.org/W2377538627","https://openalex.org/W2107220315","https://openalex.org/W1589637664","https://openalex.org/W4281727072"],"abstract_inverted_index":{"Single-cell":[0],"RNA":[1,54],"sequencing":[2],"is":[3,18,25],"a":[4,56,73,97],"valuable":[5],"technique":[6],"for":[7,129],"identifying":[8],"diverse":[9],"cell":[10,80,145],"subtypes.":[11],"A":[12],"key":[13],"challenge":[14],"in":[15,52,68,108,124,135],"this":[16],"process":[17],"that":[19,59],"the":[20],"detection":[21],"of":[22,38],"rare":[23,61,94,110,132,144],"cells":[24,62,111],"often":[26],"missed":[27],"by":[28,63],"conventional":[29],"methods":[30],"due":[31],"to":[32,82,88,93,100,121],"low":[33],"abundance":[34],"and":[35,134],"subtle":[36],"features":[37,65],"these":[39,69],"cells.":[40,70],"To":[41],"overcome":[42],"this,":[43],"we":[44],"developed":[45],"SCLCNF":[46,71],"(Local":[47],"Connectivity":[48],"Network":[49],"Feature":[50],"Sharing":[51],"Single-Cell":[53],"sequencing),":[55],"novel":[57],"approach":[58],"identifies":[60],"analyzing":[64],"uniquely":[66],"expressed":[67],"creates":[72],"cellular":[74],"connectivity":[75],"network,":[76],"considering":[77],"how":[78],"each":[79],"relates":[81],"its":[83],"neighbors.":[84],"This":[85],"network":[86],"helps":[87],"pinpoint":[89],"coexpression":[90],"patterns":[91],"unique":[92],"cells,":[95,133],"utilizing":[96],"rarity":[98],"score":[99],"confirm":[101],"their":[102],"presence.":[103],"Our":[104],"method":[105],"performs":[106],"better":[107],"detecting":[109],"than":[112],"existing":[113],"techniques,":[114],"offering":[115],"enhanced":[116],"robustness.":[117],"It":[118],"has":[119],"proven":[120],"be":[122],"effective":[123],"human":[125],"gastrula":[126],"data":[127,137],"sets":[128,138],"accurately":[130],"pinpointing":[131],"sepsis":[136],"where":[139],"it":[140],"uncovers":[141],"previously":[142],"unidentified":[143],"populations.":[146]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-07-22T07:51:19.307946","created_date":"2025-10-10T00:00:00"}