{"id":"https://openalex.org/W4405022898","doi":"https://doi.org/10.1021/acs.jcim.4c00789","title":"SmartGraph API: Programmatic Knowledge Mining in Network-Pharmacology Setting","display_name":"SmartGraph API: Programmatic Knowledge Mining in Network-Pharmacology Setting","publication_year":2024,"publication_date":"2024-12-04","ids":{"openalex":"https://openalex.org/W4405022898","doi":"https://doi.org/10.1021/acs.jcim.4c00789","pmid":"https://pubmed.ncbi.nlm.nih.gov/39630926"},"language":"en","primary_location":{"id":"doi:10.1021/acs.jcim.4c00789","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.4c00789","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1021/acs.jcim.4c00789","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026017430","display_name":"Gergely Zahor\u00e1nszky-K\u00f6halmi","orcid":"https://orcid.org/0000-0002-2534-8770"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Gergely Zahor\u00e1nszky-K\u0151halmi","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042450149","display_name":"Brandon Walker","orcid":null},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brandon Walker","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103271522","display_name":"Nathan Miller","orcid":"https://orcid.org/0000-0002-8934-7857"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nathan Miller","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112896874","display_name":"Brett Yang","orcid":null},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brett Yang","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111113544","display_name":"Dhatri V. L. Penna","orcid":null},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dhatri V. L. Penna","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114998973","display_name":"Jessica Maine","orcid":null},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica Maine","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058858658","display_name":"Timothy Sheils","orcid":"https://orcid.org/0000-0002-9987-3738"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy Sheils","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000391539","display_name":"Ke Will Wang","orcid":"https://orcid.org/0009-0009-8317-8106"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ke Wang","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080554929","display_name":"Jennifer King","orcid":"https://orcid.org/0009-0002-3794-5828"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer King","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044137956","display_name":"Hythem Sidky","orcid":"https://orcid.org/0000-0003-3532-4809"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hythem Sidky","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093731786","display_name":"Sridhar Vuyyuru","orcid":null},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sridhar Vuyyuru","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093731787","display_name":"Jeyaraman Soundarajan","orcid":null},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeyaraman Soundarajan","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018114066","display_name":"Michael D. Samuel","orcid":"https://orcid.org/0000-0002-4267-2724"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Samuel G. Michael","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036949252","display_name":"Alexander G. Godfrey","orcid":"https://orcid.org/0000-0003-3386-537X"},"institutions":[{"id":"https://openalex.org/I4210148682","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210148682"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexander G. Godfrey","raw_affiliation_strings":["National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States"],"affiliations":[{"raw_affiliation_string":"National Center for Advancing Translational Sciences (NCATS/NIH), 9800 Medical Center Dr., Rockville, Maryland 20850, United States","institution_ids":["https://openalex.org/I4210148682"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061685157","display_name":"Tudor I. Oprea","orcid":"https://orcid.org/0000-0002-6195-6976"},"institutions":[{"id":"https://openalex.org/I169521973","display_name":"University of New Mexico","ror":"https://ror.org/05fs6jp91","country_code":"US","type":"education","lineage":["https://openalex.org/I169521973"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tudor I. Oprea","raw_affiliation_strings":["Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131, United States","Expert Systems Inc., 12730 High Bluff Drive, Suite 100, San Diego, California 92130, United States"],"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131, United States","institution_ids":["https://openalex.org/I169521973"]},{"raw_affiliation_string":"Expert Systems Inc., 12730 High Bluff Drive, Suite 100, San Diego, California 92130, United States","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5026017430"],"corresponding_institution_ids":["https://openalex.org/I4210148682"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.26154229,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"64","issue":"24","first_page":"9021","last_page":"9026"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9865000247955322,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.8784810304641724},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7610371112823486},{"id":"https://openalex.org/keywords/analytics","display_name":"Analytics","score":0.5952271819114685},{"id":"https://openalex.org/keywords/application-programming-interface","display_name":"Application programming interface","score":0.5560669302940369},{"id":"https://openalex.org/keywords/interface","display_name":"Interface (matter)","score":0.4698841869831085},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.45408135652542114},{"id":"https://openalex.org/keywords/software-engineering","display_name":"Software engineering","score":0.42799103260040283},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.4157021939754486},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.2900071144104004},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.23219230771064758},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.1617303192615509},{"id":"https://openalex.org/keywords/operating-system","display_name":"Operating system","score":0.1297963559627533}],"concepts":[{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.8784810304641724},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7610371112823486},{"id":"https://openalex.org/C79158427","wikidata":"https://www.wikidata.org/wiki/Q485396","display_name":"Analytics","level":2,"score":0.5952271819114685},{"id":"https://openalex.org/C99613125","wikidata":"https://www.wikidata.org/wiki/Q165194","display_name":"Application programming interface","level":2,"score":0.5560669302940369},{"id":"https://openalex.org/C113843644","wikidata":"https://www.wikidata.org/wiki/Q901882","display_name":"Interface (matter)","level":4,"score":0.4698841869831085},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.45408135652542114},{"id":"https://openalex.org/C115903868","wikidata":"https://www.wikidata.org/wiki/Q80993","display_name":"Software engineering","level":1,"score":0.42799103260040283},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.4157021939754486},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.2900071144104004},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.23219230771064758},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.1617303192615509},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.1297963559627533},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C129307140","wikidata":"https://www.wikidata.org/wiki/Q6795880","display_name":"Maximum bubble pressure method","level":3,"score":0.0},{"id":"https://openalex.org/C157915830","wikidata":"https://www.wikidata.org/wiki/Q2928001","display_name":"Bubble","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086382","descriptor_name":"COVID-19","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000086402","descriptor_name":"SARS-CoV-2","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D000091484","descriptor_name":"Network Pharmacology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000091484","descriptor_name":"Network Pharmacology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000091484","descriptor_name":"Network Pharmacology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000091484","descriptor_name":"Network Pharmacology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012984","descriptor_name":"Software","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016208","descriptor_name":"Databases, Factual","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D055808","descriptor_name":"Drug Discovery","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057188","descriptor_name":"Workflow","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D057225","descriptor_name":"Data Mining","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1021/acs.jcim.4c00789","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.4c00789","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},{"id":"pmid:39630926","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39630926","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of chemical information and modeling","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:11683868","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11683868","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11683868/pdf/ci4c00789.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"J Chem Inf Model","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1021/acs.jcim.4c00789","is_oa":true,"landing_page_url":"https://doi.org/10.1021/acs.jcim.4c00789","pdf_url":null,"source":{"id":"https://openalex.org/S167262187","display_name":"Journal of Chemical Information and Modeling","issn_l":"1549-9596","issn":["1549-9596","1549-960X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Chemical Information and Modeling","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4099999964237213,"id":"https://metadata.un.org/sdg/9","display_name":"Industry, innovation and infrastructure"}],"awards":[{"id":"https://openalex.org/G2131148316","display_name":null,"funder_award_id":"ZIC TR000410-05","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"},{"id":"https://openalex.org/G2789588635","display_name":null,"funder_award_id":"NCATS","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3458986460","display_name":null,"funder_award_id":"TR000410-05","funder_id":"https://openalex.org/F4320337472","funder_display_name":"National Center for Advancing Translational Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337472","display_name":"National Center for Advancing Translational Sciences","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1956024495","https://openalex.org/W2060531713","https://openalex.org/W2062584010","https://openalex.org/W2087563523","https://openalex.org/W2096541451","https://openalex.org/W2096560421","https://openalex.org/W2132022337","https://openalex.org/W2159675211","https://openalex.org/W2170146596","https://openalex.org/W2539985226","https://openalex.org/W2558366645","https://openalex.org/W2558999090","https://openalex.org/W2767891136","https://openalex.org/W2899292521","https://openalex.org/W2900569176","https://openalex.org/W2949311246","https://openalex.org/W2957193018","https://openalex.org/W2998400169","https://openalex.org/W3013783109","https://openalex.org/W3094762523","https://openalex.org/W4220819463","https://openalex.org/W4294216483","https://openalex.org/W4294576509","https://openalex.org/W4307468223","https://openalex.org/W4308955036","https://openalex.org/W4309506674","https://openalex.org/W4310240482"],"related_works":["https://openalex.org/W1981780420","https://openalex.org/W2182707996","https://openalex.org/W45233828","https://openalex.org/W2964988449","https://openalex.org/W2397952901","https://openalex.org/W2029380707","https://openalex.org/W188202134","https://openalex.org/W4255934811","https://openalex.org/W2465382974","https://openalex.org/W2019038080"],"abstract_inverted_index":{"The":[0,108],"recent":[1],"SmartGraph":[2,81,112],"platform":[3,76],"facilitates":[4],"the":[5,14,19,26,29,55,58,64,74,80,88,95,100,111,119],"execution":[6],"of":[7,21,31,57,66,73,110,122],"complex":[8],"drug-discovery":[9],"workflows":[10],"with":[11],"ease":[12],"in":[13,46],"network-pharmacology":[15],"paradigm.":[16],"However,":[17],"at":[18,54],"time":[20,56],"its":[22],"publication":[23],"we":[24],"identified":[25],"need":[27,51],"for":[28],"development":[30],"an":[32,47,68],"Application":[33],"Programming":[34],"Interface":[35],"(API)":[36],"that":[37,85],"could":[38],"promote":[39],"biomedical":[40],"data":[41],"integration":[42,121],"and":[43,126,133],"hypothesis":[44],"generation":[45],"automated":[48,106],"manner.":[49],"This":[50,61],"was":[52],"magnified":[53],"COVID-19":[59],"pandemic.":[60],"study":[62],"addresses":[63],"absence":[65],"such":[67],"API.":[69,82],"Accordingly,":[70],"most":[71],"functionalities":[72,132],"original":[75,96],"were":[77],"implemented":[78],"within":[79],"We":[83],"demonstrate":[84],"by":[86],"using":[87],"API":[89,113],"it":[90],"is":[91],"possible":[92],"to":[93,103,118],"transform":[94],"semiautomated":[97],"workflow":[98],"behind":[99],"Neo4COVID19":[101],"database":[102],"a":[104,115],"fully":[105],"one.":[107],"availability":[109],"lends":[114],"significant":[116],"improvement":[117],"programmatic":[120],"network-pharmacology-oriented":[123],"knowledge":[124],"graphs":[125],"analytics,":[127],"as":[128,130],"well":[129],"predictive":[131],"workflows.":[134]},"counts_by_year":[],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}